KEGG   ENZYME: 1.13.12.1
Entry
EC 1.13.12.1                Enzyme                                 

Name
arginine 2-monooxygenase;
arginine monooxygenase;
arginine decarboxylase (incorrect);
arginine oxygenase (decarboxylating);
arginine decarboxy-oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
Sysname
L-arginine:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O [RN:R00559]
Reaction(KEGG)
R00559
Substrate
L-arginine [CPD:C00062];
O2 [CPD:C00007]
Product
4-guanidinobutanamide [CPD:C03078];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A flavoprotein. Also acts on canavanine and homoarginine.
History
EC 1.13.12.1 created 1972
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:4295160]
  Authors
Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV.
  Title
[Arginine oxygenase (decarboxylating). V. Purification and flavin nature]
  Journal
Biochim Biophys Acta 151:353-66 (1968)
DOI:10.1016/0005-2744(68)90102-2
Reference
2  [PMID:14479405]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. I. Characteristics and nature of the enzyme].
  Journal
Biochim Biophys Acta 59:533-44 (1962)
DOI:10.1016/0006-3002(62)90631-5
Reference
3  [PMID:14479406]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. II. Oxidation of canavanine and homoarginine to beta-guanidoxy-propionamide and delta-guanidovaleramide].
  Journal
Biochim Biophys Acta 59:545-52 (1962)
DOI:10.1016/0006-3002(62)90632-7
Other DBs
ExplorEnz - The Enzyme Database: 1.13.12.1
IUBMB Enzyme Nomenclature: 1.13.12.1
ExPASy - ENZYME nomenclature database: 1.13.12.1
BRENDA, the Enzyme Database: 1.13.12.1
CAS: 9027-36-5

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Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
All databases (13)   

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KEGG   REACTION: R00559
Entry
R00559                      Reaction                               

Name
L-Arginine:oxygen 2-oxidoreductase (decarboxylating)
Definition
L-Arginine + Oxygen <=> 4-Guanidinobutanamide + CO2 + H2O
Equation
Reaction class
RC00213  C00062_C03078
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Other DBs
RHEA: 10551

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
All databases (12)   

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