KEGG   ENZYME: 1.4.3.7
Entry
EC 1.4.3.7                  Enzyme                                 

Name
D-glutamate oxidase;
D-glutamic oxidase;
D-glutamic acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Sysname
D-glutamate:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2 [RN:R00279]
Reaction(KEGG)
R00279;
(other) R06124
Substrate
D-glutamate [CPD:C00217];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
2-oxoglutarate [CPD:C00026];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
History
EC 1.4.3.7 created 1972
Pathway
ec00471  D-Glutamine and D-glutamate metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:13583997]
  Authors
ROCCA E, GHIRETTI F.
  Title
Purification and properties of D-glutamic acid oxidase from Octopus vulgaris Lam.
  Journal
Arch Biochem Biophys 77:336-49 (1958)
DOI:10.1016/0003-9861(58)90081-X
Reference
2  [PMID:4387700]
  Authors
Urich K.
  Title
[D-Glutamate oxidase from the antennal gland of the crayfish Oronectes limosus: purification and characterization]
  Journal
Z Naturforsch B 23:1508-11 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.7
IUBMB Enzyme Nomenclature: 1.4.3.7
ExPASy - ENZYME nomenclature database: 1.4.3.7
BRENDA, the Enzyme Database: 1.4.3.7
CAS: 37255-41-7

KEGG   ENZYME: 1.4.3.15
Entry
EC 1.4.3.15                 Enzyme                                 

Name
D-glutamate(D-aspartate) oxidase;
D-glutamic-aspartic oxidase;
D-monoaminodicarboxylic acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Sysname
D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
(1) D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2 [RN:R00279];
(2) D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
Reaction(KEGG)
R00279;
(other) R00359
Substrate
D-glutamate [CPD:C00217];
H2O [CPD:C00001];
O2 [CPD:C00007];
D-aspartate [CPD:C00402]
Product
2-oxoglutarate [CPD:C00026];
NH3 [CPD:C00014];
H2O2 [CPD:C00027];
oxaloacetate [CPD:C00036]
Comment
A flavoprotein (FAD). D-Glutamate and D-aspartate are oxidized at the same rate. Other D-monoaminodicarboxylates, and other D- and L-amino acids, are not oxidized. cf. EC 1.4.3.7, D-glutamate oxidase and EC 1.4.3.1, D-aspartate oxidase.
History
EC 1.4.3.15 created 1983, modified 2012
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec00471  D-Glutamine and D-glutamate metabolism
ec01100  Metabolic pathways
Reference
1
  Authors
Mizushima, S.
  Title
Purified D-glutamic-aspartic oxidase of Aspergillus ustus.
  Journal
J Gen Appl Microbiol 3:233-239 (1957)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.15
IUBMB Enzyme Nomenclature: 1.4.3.15
ExPASy - ENZYME nomenclature database: 1.4.3.15
BRENDA, the Enzyme Database: 1.4.3.15
CAS: 9029-20-3

KEGG   REACTION: R00279
Entry
R00279                      Reaction                               

Name
D-Glutamate:oxygen oxidoreductase (deaminating)
Definition
D-Glutamate + H2O + Oxygen <=> 2-Oxoglutarate + Ammonia + Hydrogen peroxide
Equation
Reaction class
RC00006  C00026_C00217
RC02755  C00007_C00027
Enzyme
1.4.3.7         1.4.3.15
Pathway
rn00471  D-Glutamine and D-glutamate metabolism
rn01100  Metabolic pathways
Other DBs
RHEA: 10031

DBGET integrated database retrieval system