KEGG   ENZYME: 2.1.1.40
Entry
EC 2.1.1.40                 Enzyme                                 

Name
inositol 1-methyltransferase;
inositol D-1-methyltransferase;
S-adenosylmethionine:myo-inositol 3-methyltransferase;
myo-inositol 3-O-methyltransferase;
inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering);
S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-1-O-methyl-myo-inositol [RN:R01188]
Reaction(KEGG)
R01188
Substrate
S-adenosyl-L-methionine [CPD:C00019];
myo-inositol [CPD:C00137]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
1D-1-O-methyl-myo-inositol [CPD:C03659]
History
EC 2.1.1.40 created 1972, modified 2002
Pathway
ec00562  Inositol phosphate metabolism
Reference
1  [PMID:5362620]
  Authors
Wagner I, Hofmann H, Hoffmann-Ostenhof O.
  Title
[Biosynthesis of cyclitols. 23. A soluble enzyme from pea seedlings methylating myo-inositol to D-bornesitol]
  Journal
Hoppe Seylers Z Physiol Chem 350:1460-4 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.40
IUBMB Enzyme Nomenclature: 2.1.1.40
ExPASy - ENZYME nomenclature database: 2.1.1.40
BRENDA, the Enzyme Database: 2.1.1.40
CAS: 37257-06-0

KEGG   REACTION: R01188
Entry
R01188                      Reaction                               

Name
S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase
Definition
S-Adenosyl-L-methionine + myo-Inositol <=> S-Adenosyl-L-homocysteine + D-Bornesitol
Equation
Comment
formerly called "myo-Inositol 3-O-methyltransferase" on old nomenclature system of inositol numbering
Reaction class
RC00003  C00019_C00021
RC00466  C00137_C03659
Enzyme
Pathway
rn00562  Inositol phosphate metabolism
Other DBs
RHEA: 17568

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