KEGG   ENZYME: 2.7.3.5
Entry
EC 2.7.3.5                  Enzyme                                 

Name
lombricine kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a nitrogenous group as acceptor
Sysname
ATP:lombricine N-phosphotransferase
Reaction(IUBMB)
ATP + lombricine = ADP + N-phospholombricine [RN:R06976]
Reaction(KEGG)
R06976;
(other) R03691
Substrate
ATP [CPD:C00002];
lombricine [CPD:C14177]
Product
ADP [CPD:C00008];
N-phospholombricine [CPD:C14178]
Comment
Also acts on methylated lombricines such as thalassemine; the specificity varies with the source species.
History
EC 2.7.3.5 created 1965, modified 1976
Pathway
ec00260  Glycine, serine and threonine metabolism
Reference
1  [PMID:5832288]
  Authors
Gaffney TJ, Rosenberg H, Ennor AH.
  Title
The purification and properties of adenosine triphosphate-lombricine phosphotransferase.
  Journal
Biochem J 90:170-6 (1964)
DOI:10.1042/bj0900170
Reference
2  [PMID:5840960]
  Authors
Kassab R, Pradel LA, Nguyen Van Thoai.
  Title
[ATP:taurocyamine and ATP:lombricine phosphotransferases. Purification and study of SH groups]
  Journal
Biochim Biophys Acta 99:397-405 (1965)
Reference
3  [PMID:14430183]
  Authors
PANT R.
  Title
Isolation of lombricine and its enzymic phosphorylation.
  Journal
Biochem J 73:30-3 (1959)
DOI:10.1042/bj0730030
Reference
4  [PMID:5079888]
  Authors
van Thoai N, Robin Y, Guillou Y.
  Title
A new phosphagen, N'-phosphorylguanidinoethylphospho-O-( -N,N-dimethyl)serine (phosphothalassemine).
  Journal
Biochemistry 11:3890-5 (1972)
DOI:10.1021/bi00771a009
Other DBs
ExplorEnz - The Enzyme Database: 2.7.3.5
IUBMB Enzyme Nomenclature: 2.7.3.5
ExPASy - ENZYME nomenclature database: 2.7.3.5
BRENDA, the Enzyme Database: 2.7.3.5
CAS: 9026-53-3

KEGG   REACTION: R03691
Entry
R03691                      Reaction                               

Name
ATP:lombricine N-phosphotransferase
Definition
ATP + D-Lombricine <=> ADP + N-Phospho-D-lombricine
Equation
Reaction class
RC00002  C00002_C00008
RC00203  C01726_C02855
Enzyme
Pathway
rn00260  Glycine, serine and threonine metabolism

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