KEGG   ENZYME: 2.7.4.32Help
Entry
EC 2.7.4.32                 Enzyme                                 

Name
farnesyl phosphate kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
BRITE hierarchy
Sysname
CTP:(2E,6E)-farnesyl-phosphate phosphotransferase
Reaction(IUBMB)
CTP + (2E,6E)-farnesyl phosphate = CDP + (2E,6E)-farnesyl diphosphate [RN:R09850]
Reaction(KEGG)
Substrate
CTP [CPD:C00063];
(2E,6E)-farnesyl phosphate [CPD:C20121]
Product
CDP [CPD:C00112];
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Comment
The enzyme, found in plants and animals, is specific for CTP as phosphate donor. It does not use farnesol as substrate (cf. EC 2.7.1.216, farnesol kinase).
History
EC 2.7.4.32 created 2017
Pathway
ec00900  Terpenoid backbone biosynthesis
ec01130  Biosynthesis of antibiotics
Reference
1  [PMID:9606952]
  Authors
Bentinger M, Grunler J, Peterson E, Swiezewska E, Dallner G
  Title
Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase.
  Journal
Arch Biochem Biophys 353:191-8 (1998)
DOI:10.1006/abbi.1998.0611
Reference
2  [PMID:21395888]
  Authors
Fitzpatrick AH, Bhandari J, Crowell DN.
  Title
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
  Journal
Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x
Other DBs
ExplorEnz - The Enzyme Database: 2.7.4.32
IUBMB Enzyme Nomenclature: 2.7.4.32
ExPASy - ENZYME nomenclature database: 2.7.4.32
BRENDA, the Enzyme Database: 2.7.4.32

KEGG   REACTION: R09850Help
Entry
R09850                      Reaction                               

Name
CTP:farnesyl-phosphate phosphotransferase
Definition
trans,trans-Farnesyl phosphate + CTP <=> trans,trans-Farnesyl diphosphate + CDP
Equation
Comment
enzyme not yet characterized
Reaction class
RC00002  C00063_C00112  C00448_C20121
Enzyme
Pathway
rn00900  Terpenoid backbone biosynthesis
rn01130  Biosynthesis of antibiotics
Other DBs
RHEA: 51687

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