KEGG   ENZYME: 4.1.2.32
Entry
EC 4.1.2.32                 Enzyme                                 

Name
trimethylamine-oxide aldolase;
trimethylamine N-oxide formaldehyde-lyase;
trimethylamine N-oxide aldolase;
trimethylamine N-oxide demethylase;
trimethylamine-N-oxide formaldehyde-lyase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
Sysname
trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)
Reaction(IUBMB)
trimethylamine N-oxide = dimethylamine + formaldehyde [RN:R02512]
Reaction(KEGG)
R02512
Substrate
trimethylamine N-oxide [CPD:C01104]
Product
dimethylamine [CPD:C00543];
formaldehyde [CPD:C00067]
History
EC 4.1.2.32 created 1978
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:11946146]
  Authors
Large PJ.
  Title
Non-oxidative demethylation of trimethylamine N-oxide by Pseudomonas aminovorans.
  Journal
FEBS Lett 18:297-300 (1971)
DOI:10.1016/0014-5793(71)80470-2
Reference
2  [PMID:5116524]
  Authors
Myers PA, Zatman LJ.
  Title
The metabolism of trimethylamine N-oxide by Bacillus PM6.
  Journal
Biochem J 121:10P (1971)
DOI:10.1042/bj1210010pa
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.32
IUBMB Enzyme Nomenclature: 4.1.2.32
ExPASy - ENZYME nomenclature database: 4.1.2.32
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.2.32
BRENDA, the Enzyme Database: 4.1.2.32
CAS: 72561-08-1

  All links  
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Protein sequence (40)   
   UniProt (2)   
   RefSeq(pep) (38)   
DNA sequence (59)   
   RefSeq(nuc) (50)   
   GenBank (5)   
   EMBL (4)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (112)   

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KEGG   REACTION: R02512
Entry
R02512                      Reaction                               

Name
Trimethylamine-N-oxide formaldehyde-lyase
Definition
Trimethylamine N-oxide <=> Dimethylamine + Formaldehyde
Equation
Reaction class
RC00733  C00067_C01104
RC00734  C00543_C01104
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Other DBs
RHEA: 20220

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   UMBBD-RN (1)   
All databases (14)   

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