KEGG   ENZYME: 4.2.1.146
Entry
EC 4.2.1.146                Enzyme                                 
Name
L-galactonate dehydratase;
LGD1
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)
Reaction(IUBMB)
L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O [RN:R10532]
Reaction(KEGG)
R10532
Substrate
L-galactonate [CPD:C15930]
Product
2-dehydro-3-deoxy-L-galactonate [CPD:C20680];
H2O [CPD:C00001]
Comment
The enzyme takes part in a D-galacturonate degradation pathway in the fungi Trichoderma reesei (Hypocrea jecorina) and Aspergillus niger.
History
EC 4.2.1.146 created 2013
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18102  L-galactonate dehydratase
Genes
PGU: PGUG_05189
CTEN: 18249897(PSN45_000413)
PPA: PAS_chr4_0572
SLB: AWJ20_3253 AWJ20_3295
NCR: NCU07064
NTE: NEUTE1DRAFT131658(NEUTE1DRAFT_131658)
SMP: 10805217(SMAC4_03881)
PAN: PODANSg3017
PBEL: QC761_408390(LGD1)
PPSD: 87910200(LGD1)
PPSP: QC763_408390(LGD1)
PPSA: QC764_408390(LGD1)
TTT: THITE_2153466
MTM: MYCTH_2064932 MYCTH_82505
CTHR: CTHT_0042160
RTHE: 98126834(VTJ83DRAFT_5575)
MGR: MGG_01300
PPEI: PpBr36_00810
PGRI: PgNI_04224
TMN: UCRPA7_2751 UCRPA7_4700
SSCK: SPSK_00800 SPSK_03340 SPSK_06299
FGR: FGSG_09257
FPU: FPSE_09649
FPOA: FPOAC1_012439(LGD1)
FVN: FVRRES_13523
FVR: FVEG_03852 FVEG_12512 FVEG_12549
FOX: FOXG_05984 FOXG_15221 FOXG_17432
NHE: NECHADRAFT_56323 NECHADRAFT_66837
FFC: NCS54_00305100 NCS54_00875300
FKR: NCS57_00300500 NCS57_01447900
FMU: J7337_003423(LGD1_1) J7337_003862(LGD1_2) J7337_007844
TRE: TRIREDRAFT_104599 TRIREDRAFT_66662
TRR: M419DRAFT_11053 M419DRAFT_73300
TATV: 25783197(TrAtP1_012155) 25783628(TrAtP1_003853)
TASP: 36607139(LGD1_1) 36611155(LGD1_2)
MAW: 19247715(LGD1_1)
MAJ: MAA_02004
MBRN: 26239597(lgd1)
PCHM: VFPPC_09660 VFPPC_10154 VFPPC_14026 VFPPC_15420
UVI: 66061425(UV8b_00647)
CMT: CCM_00320
AMUS: LMH87_000566
PLJ: 28886244(PLICBS_007730) 28889812(PLICBS_008771)
PTKZ: JDV02_004411(LGD1)
DCON: 63714414(DCS_01771)
VAL: VDBG_08188
VDA: VDAG_10081
CFJ: CFIO01_10120
CLUP: CLUP02_16470
CHIG: CH63R_14134
CDET: 87947706(CDEST_11206)
SAPO: SAPIO_CDS5438 SAPIO_CDS6402
ELA: UCREL1_8211
PFY: PFICI_14149
SSL: SS1G_12905
BFU: BCIN_01g09450(Bclgd1)
MBE: MBM_09691
PSCO: LY89DRAFT_610683
GLZ: GLAREA_00035
ANI: ANIA_06035
AFM: AFUA_2G09810
ACT: ACLA_068890
NFI: NFIA_085260
AOR: AO090011000654
ANG: An16g05390
AFV: AFLA_008058
ALUC: AKAW2_70451A(LGD1)
ACHE: ACHE_40955S(LGD1)
APUU: APUU_11124A(LGD1)
PCS: N7525_004390 N7525_011616
PDP: PDIP_64950
POU: POX_f07869
PPSF: 300786780(PFLUO_LOCUS1294) 300789511(PFLUO_LOCUS3752) 300793234(PFLUO_LOCUS7103) 300795153(PFLUO_LOCUS8831)
TMF: EYB26_004761
TRG: TRUGW13939_01876 TRUGW13939_04485
ABE: ARB_05174
TVE: TRV_03587
PNO: SNOG_13604
PTE: PTT_15544
PTRR: 6349555(PtrM4_071580)
BZE: COCCADRAFT_3106
BSC: COCSADRAFT_180831
BOR: COCMIDRAFT_2503
AALT: CC77DRAFT_1017550
ADAC: 96081371(ACET3X_001049)
ARAB: EKO05_0010953
ZTR: MYCGRDRAFT_71623
PFJ: MYCFIDRAFT_37783
FFU: CLAFUR5_08447
CBET: CB0940_04302
BCOM: BAUCODRAFT_37158
NPA: UCRNP2_9857
TML: GSTUM_00012245001
KDJ: 28971260(I303_107551)
KBI: 30212121(I302_108584)
KER: 91102215(V865_003411)
KBO: 90014468(L199_003484)
TMS: TREMEDRAFT_30567 TREMEDRAFT_58672
TASA: A1Q1_01111
 » show all
Reference
1  [PMID:16879654]
  Authors
Kuorelahti S, Jouhten P, Maaheimo H, Penttila M, Richard P
  Title
L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism.
  Journal
Mol Microbiol 61:1060-8 (2006)
DOI:10.1111/j.1365-2958.2006.05294.x
  Sequence
[tre:TRIREDRAFT_104599]
Reference
2  [PMID:18768163]
  Authors
Martens-Uzunova ES, Schaap PJ
  Title
An evolutionary conserved d-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation.
  Journal
Fungal Genet Biol 45:1449-57 (2008)
DOI:10.1016/j.fgb.2008.08.002
  Sequence
[ang:An16g05390]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.146
IUBMB Enzyme Nomenclature: 4.2.1.146
ExPASy - ENZYME nomenclature database: 4.2.1.146
BRENDA, the Enzyme Database: 4.2.1.146

  All links  
Gene (53)   
   MGENES (7)   
   RefGene (46)   
Protein sequence (3)   
   UniProt (2)   
   SWISS-PROT (1)   
DNA sequence (8)   
   GenBank (5)   
   EMBL (3)   
All databases (64)   

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