KEGG   COMPOUND: C00037
Entry
C00037                      Compound                               

Name
Glycine;
Aminoacetic acid;
Gly
Formula
C2H5NO2
Exact mass
75.032
Mol weight
75.0666
Structure
Remark
Same as: D00011
Reaction
Pathway
map00120  Primary bile acid biosynthesis
map00230  Purine metabolism
map00260  Glycine, serine and threonine metabolism
map00310  Lysine degradation
map00440  Phosphonate and phosphinate metabolism
map00460  Cyanoamino acid metabolism
map00480  Glutathione metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00680  Methane metabolism
map00730  Thiamine metabolism
map00860  Porphyrin and chlorophyll metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01502  Vancomycin resistance
map02010  ABC transporters
map02026  Biofilm formation - Escherichia coli
map04080  Neuroactive ligand-receptor interaction
map04721  Synaptic vesicle cycle
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00346  Formaldehyde assimilation, serine pathway
M00532  Photorespiration
M00868  Heme biosynthesis, animals and fungi, glycine => heme
M00895  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP
M00896  Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
M00897  Thiamine biosynthesis, plants, AIR (+ NAD+) => TMP/thiamine/TPP
M00898  Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
Enzyme
1.4.1.1         1.4.1.10        1.4.1.27        1.4.2.1         
1.4.3.3         1.4.3.19        1.4.4.2         1.4.99.5        
1.5.1.22        1.5.3.1         1.5.8.3         1.13.11.78      
1.21.4.2        2.1.1.20        2.1.1.156       2.1.1.162       
2.1.2.1         2.1.2.4         2.1.4.1         2.3.1.13        
2.3.1.29        2.3.1.37        2.3.1.65        2.3.1.71        
2.3.1.192       2.3.1.-         2.3.2.15        2.3.2.-         
2.4.2.59        2.4.2.60        2.6.1.4         2.6.1.35        
2.6.1.44        2.6.1.45        2.6.1.60        2.6.1.63        
2.6.1.73        2.6.1.96        2.6.1.112       3.4.11.1        
3.4.11.2        3.4.11.23       3.4.13.23       3.4.13.-        
3.5.1.24        3.5.1.32        3.5.1.58        3.5.1.71        
3.5.3.2         4.1.2.5         4.1.2.26        4.1.2.42        
4.1.2.48        4.1.2.49        4.1.2.-         4.1.3.14        
4.1.3.41        6.1.1.14        6.3.2.3         6.3.4.13
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00037  Glycine (Gly)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00037  Glycine
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CX Other irrigating solutions
     B05CX03 Glycine
      D00011  Glycine (JP17/USP) <US>
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Glycine
    D00011  Glycine (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00011  Glycine
Other DBs
CAS: 56-40-6
PubChem: 3339
ChEBI: 15428
ChEMBL: CHEMBL773
KNApSAcK: C00001361
PDB-CCD: GLY[PDBj]
3DMET: B01136
NIKKAJI: J1.163K
KCF data

ATOM        5
            1   C6a C    24.9184  -17.1304
            2   C1b C    26.0707  -17.8870
            3   O6a O    23.6903  -17.8231
            4   O6a O    24.9418  -15.7279
            5   N1a N    27.2837  -17.2772
BOND        4
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1

» Japanese version

KEGG   COMPOUND: C00041
Entry
C00041                      Compound                               

Name
L-Alanine;
L-2-Aminopropionic acid;
L-alpha-Alanine
Formula
C3H7NO2
Exact mass
89.0477
Mol weight
89.0932
Structure
Remark
Same as: D00012
Reaction
Pathway
map00250  Alanine, aspartate and glutamate metabolism
map00270  Cysteine and methionine metabolism
map00430  Taurine and hypotaurine metabolism
map00450  Selenocompound metabolism
map00473  D-Alanine metabolism
map00710  Carbon fixation in photosynthetic organisms
map00970  Aminoacyl-tRNA biosynthesis
map00998  Biosynthesis of various secondary metabolites - part 2
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01230  Biosynthesis of amino acids
map01502  Vancomycin resistance
map02010  ABC transporters
map04122  Sulfur relay system
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00901  Fumiquinazoline biosynthesis, tryptophan + alanine + anthranilate => fumiquinazoline
Enzyme
1.4.1.1         1.5.1.17        2.3.1.47        2.6.1.2         
2.6.1.12        2.6.1.15        2.6.1.18        2.6.1.30        
2.6.1.37        2.6.1.40        2.6.1.41        2.6.1.43        
2.6.1.44        2.6.1.46        2.6.1.47        2.6.1.51        
2.6.1.56        2.6.1.58        2.6.1.66        2.6.1.71        
2.6.1.77        2.6.1.84        2.6.1.96        2.6.1.99        
2.6.1.108       2.6.1.113       2.6.1.115       2.6.1.119       
2.8.1.7         2.8.1.9         3.5.1.28        3.7.1.3         
4.1.1.12        4.1.1.64        4.4.1.16        5.1.1.1         
6.1.1.7         6.3.2.8         6.3.2.49        6.3.2.-
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00041  Alanine (Ala)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Alanine
    D00012  Alanine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00012  L-Alanine
Other DBs
CAS: 56-41-7
PubChem: 3343
ChEBI: 16977
ChEMBL: CHEMBL279597
KNApSAcK: C00001332
PDB-CCD: ALA[PDBj]
3DMET: B00011
NIKKAJI: J9.168E
KCF data

ATOM        6
            1   O6a O    22.7503  -15.7507
            2   C6a C    23.9627  -15.0506
            3   C1c C    25.1753  -15.7507
            4   C1a C    26.3878  -15.0506
            5   O6a O    23.9627  -13.6508
            6   N1a N    25.1753  -17.1506
BOND        5
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     2   5 2
            5     3   6 1 #Down

» Japanese version

KEGG   COMPOUND: C00183
Entry
C00183                      Compound                               

Name
L-Valine;
2-Amino-3-methylbutyric acid
Formula
C5H11NO2
Exact mass
117.079
Mol weight
117.1463
Structure
Remark
Same as: D00039
Reaction
Pathway
map00280  Valine, leucine and isoleucine degradation
map00290  Valine, leucine and isoleucine biosynthesis
map00311  Penicillin and cephalosporin biosynthesis
map00460  Cyanoamino acid metabolism
map00770  Pantothenate and CoA biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00672  Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Enzyme
1.4.1.8         1.4.1.9         1.4.1.23        1.14.14.38      
1.14.14.39      2.6.1.6         2.6.1.32        2.6.1.42        
2.6.1.66        4.1.1.14        6.1.1.9         6.3.2.26        
6.3.2.47
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00183  Valine (Val)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Valine
    D00039  Valine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00039  L-Valine
Other DBs
CAS: 72-18-4
PubChem: 3483
ChEBI: 16414
ChEMBL: CHEMBL43068
KNApSAcK: C00001398
PDB-CCD: VAL[PDBj]
3DMET: B00054
NIKKAJI: J9.179K
KCF data

ATOM        8
            1   C1c C    24.8500  -19.0764
            2   C1c C    26.0666  -18.3804
            3   C6a C    23.6334  -18.3629
            4   N1a N    24.8442  -20.4802
            5   C1a C    27.2716  -19.0881
            6   C1a C    26.0725  -16.9825
            7   O6a O    22.4226  -19.0589
            8   O6a O    23.6392  -16.9707
BOND        7
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 2

» Japanese version

KEGG   COMPOUND: C00123
Entry
C00123                      Compound                               

Name
L-Leucine;
2-Amino-4-methylvaleric acid;
(2S)-alpha-2-Amino-4-methylvaleric acid;
(2S)-alpha-Leucine
Formula
C6H13NO2
Exact mass
131.0946
Mol weight
131.1729
Structure
Remark
Same as: D00030
Reaction
Pathway
map00280  Valine, leucine and isoleucine degradation
map00290  Valine, leucine and isoleucine biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04150  mTOR signaling pathway
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05131  Shigellosis
map05230  Central carbon metabolism in cancer
Module
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Enzyme
1.4.1.9         1.14.13.-       2.3.1.66        2.6.1.6         
2.6.1.42        2.6.1.67        3.5.1.64        5.4.3.7         
6.1.1.4         6.3.2.47
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00123  Leucine (Leu)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Leucine
    D00030  Leucine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00030  L-Leucine
Other DBs
CAS: 61-90-5
PubChem: 3423
ChEBI: 15603
ChEMBL: CHEMBL291962
KNApSAcK: C00001377
PDB-CCD: LEU[PDBj]
3DMET: B00034
NIKKAJI: J1.167C
KCF data

ATOM        9
            1   C1c C    25.0761  -19.4138
            2   C1b C    26.2633  -18.6769
            3   C6a C    23.8420  -18.7586
            4   N1a N    25.1229  -20.8173
            5   C1c C    27.4974  -19.3377
            6   O6a O    22.6841  -19.5483
            7   O6a O    23.8654  -17.3551
            8   C1a C    28.6846  -18.6007
            9   C1a C    27.5442  -20.7356
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     5   9 1

» Japanese version

KEGG   COMPOUND: C00073
Entry
C00073                      Compound                               

Name
L-Methionine;
Methionine;
L-2-Amino-4methylthiobutyric acid
Formula
C5H11NO2S
Exact mass
149.051
Mol weight
149.2113
Structure
Remark
Same as: D00019
Reaction
Pathway
map00270  Cysteine and methionine metabolism
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01523  Antifolate resistance
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00017  Methionine biosynthesis, apartate => homoserine => methionine
M00034  Methionine salvage pathway
M00035  Methionine degradation
M00368  Ethylene biosynthesis, methionine => ethylene
M00609  Cysteine biosynthesis, methionine => cysteine
Enzyme
1.1.98.7        1.1.99.38       1.3.98.3        1.3.98.6        
1.4.3.2         1.8.4.11        1.8.4.13        1.8.4.14        
1.17.98.2       1.21.98.1       1.21.98.3       1.21.98.4       
1.97.1.4        2.1.1.3         2.1.1.5         2.1.1.10        
2.1.1.12        2.1.1.13        2.1.1.14        2.1.1.280       
2.1.1.308       2.1.1.326       2.1.1.342       2.1.1.350       
2.1.1.-         2.4.99.17       2.5.1.6         2.5.1.49        
2.5.1.63        2.5.1.94        2.5.1.120       2.5.1.147       
2.6.1.5         2.6.1.57        2.6.1.73        2.6.1.88        
2.6.1.117       2.6.1.-         2.8.1.6         2.8.1.8         
2.8.4.3         2.8.4.4         2.8.4.5         3.4.13.12       
3.5.1.31        3.13.1.8        4.1.1.57        4.1.3.44        
4.1.99.17       4.1.99.19       4.1.99.22       4.1.99.23       
4.3.1.30        4.3.1.32        4.4.1.11        4.7.1.1         
5.1.1.2         6.1.1.10
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00073  Methionine (Met)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AB Antidotes
     V03AB26 Methionine
      D00019  Methionine (USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Methionine
    D00019  Methionine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00019  L-Methionine
Other DBs
CAS: 63-68-3
PubChem: 3373
ChEBI: 16643
ChEMBL: CHEMBL42336
KNApSAcK: C00001379
PDB-CCD: MET[PDBj]
3DMET: B01148
NIKKAJI: J9.174J
KCF data

ATOM        9
            1   C1c C    24.5047  -19.4197
            2   C6a C    23.3598  -18.6719
            3   C1b C    25.7313  -18.7361
            4   N1a N    24.5455  -20.8273
            5   O6a O    22.1332  -19.3553
            6   O6a O    23.3772  -17.2641
            7   C1b C    26.9405  -19.4546
            8   S2a S    28.1672  -18.7712
            9   C1a C    29.3647  -19.4896
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     7   8 1
            8     8   9 1

» Japanese version

KEGG   COMPOUND: C00407
Entry
C00407                      Compound                               

Name
L-Isoleucine;
2-Amino-3-methylvaleric acid
Formula
C6H13NO2
Exact mass
131.0946
Mol weight
131.1729
Structure
Remark
Same as: D00065
Reaction
Pathway
map00280  Valine, leucine and isoleucine degradation
map00290  Valine, leucine and isoleucine biosynthesis
map00460  Cyanoamino acid metabolism
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05131  Shigellosis
map05230  Central carbon metabolism in cancer
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Enzyme
1.4.1.9         1.4.3.2         1.14.11.45      1.14.11.74      
1.14.14.38      1.14.14.39      2.6.1.32        2.6.1.42        
5.1.1.21        6.1.1.5         6.3.2.47        6.3.2.50
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00407  Isoleucine (Ile)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Isoleucine
    D00065  Isoleucine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00065  L-Isoleucine
Other DBs
CAS: 73-32-5
PubChem: 3697
ChEBI: 17191
ChEMBL: CHEMBL1233584 CHEMBL1869615
KNApSAcK: C00001374
PDB-CCD: ILE[PDBj]
3DMET: B01236
NIKKAJI: J2.818E
KCF data

ATOM        9
            1   C1c C    22.4922  -17.1397
            2   C1c C    23.6796  -16.4029
            3   C6a C    21.2581  -16.4789
            4   N1a N    22.5391  -18.5377
            5   C1b C    24.9137  -17.0637
            6   C1a C    23.6387  -15.0049
            7   O6a O    20.1001  -17.2742
            8   O6a O    21.2815  -15.0809
            9   C1a C    26.1069  -16.3268
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     5   9 1

» Japanese version

KEGG   COMPOUND: C00148
Entry
C00148                      Compound                               

Name
L-Proline;
2-Pyrrolidinecarboxylic acid
Formula
C5H9NO2
Exact mass
115.0633
Mol weight
115.1305
Structure
Remark
Same as: D00035
Reaction
Pathway
map00330  Arginine and proline metabolism
map00332  Carbapenem biosynthesis
map00333  Prodigiosin biosynthesis
map00401  Novobiocin biosynthesis
map00404  Staurosporine biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00015  Proline biosynthesis, glutamate => proline
M00786  Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Enzyme
1.5.1.1         1.5.1.2         1.5.1.21        1.5.1.49        
1.5.5.2         1.5.-.-         1.14.11.2       1.14.11.28      
1.14.11.56      1.14.11.57      3.4.11.5        3.5.1.101       
4.3.1.12        5.1.1.4         6.1.1.15        6.2.1.53        
6.2.1.62
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00148  Proline (Pro)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00035  L-Proline
Other DBs
CAS: 147-85-3
PubChem: 3448
ChEBI: 17203
ChEMBL: CHEMBL54922
KNApSAcK: C00001388
PDB-CCD: PRO[PDBj]
3DMET: B01173
NIKKAJI: J9.117K
KCF data

ATOM        8
            1   C1x C    10.0100  -19.3900
            2   C1x C    10.4300  -20.6500
            3   C1x C    11.8300  -20.6500
            4   C1y C    12.2500  -19.3200
            5   N1x N    11.1300  -18.4800
            6   C6a C    13.4400  -18.6200
            7   O6a O    14.7000  -19.3200
            8   O6a O    13.4400  -17.2200
BOND        8
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     4   6 1 #Down
            7     6   7 1
            8     6   8 2

» Japanese version

KEGG   COMPOUND: C00079
Entry
C00079                      Compound                               

Name
L-Phenylalanine;
(S)-alpha-Amino-beta-phenylpropionic acid
Formula
C9H11NO2
Exact mass
165.079
Mol weight
165.1891
Structure
Remark
Same as: D00021
Reaction
Pathway
map00360  Phenylalanine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00460  Cyanoamino acid metabolism
map00940  Phenylpropanoid biosynthesis
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00998  Biosynthesis of various secondary metabolites - part 2
map01060  Biosynthesis of plant secondary metabolites
map01061  Biosynthesis of phenylpropanoids
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00024  Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00137  Flavanone biosynthesis, phenylalanine => naringenin
M00891  Ditryptophenaline biosynthesis, tryptophan + phenylalanine => ditryptophenaline
M00910  Phenylalanine biosynthesis, chorismate => arogenate => phenylalanine
Enzyme
1.4.1.20        1.4.3.2         1.11.1.21       1.13.12.9       
1.14.14.40      1.14.16.1       1.14.16.7       2.3.1.53        
2.6.1.1         2.6.1.5         2.6.1.9         2.6.1.28        
2.6.1.57        2.6.1.58        2.6.1.64        2.6.1.70        
2.6.1.-         3.4.17.23       4.1.1.28        4.1.1.53        
4.1.1.109       4.2.1.51        4.2.1.91        4.3.1.24        
4.3.1.25        5.1.1.11        5.4.3.10        5.4.3.11        
6.1.1.20        6.3.2.40        6.3.2.-
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00079  Phenylalanine (Phe)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Phenylalanine
    D00021  Phenylalanine (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00021  L-Phenylalanine
Other DBs
CAS: 63-91-2
PubChem: 3379
ChEBI: 17295
ChEMBL: CHEMBL301523
KNApSAcK: C00001386
PDB-CCD: PHE[PDBj]
3DMET: B01151
NIKKAJI: J9.175H
KCF data

ATOM        12
            1   C8y C    25.3400  -16.0300
            2   C8x C    25.3400  -17.5000
            3   C8x C    24.0800  -18.2000
            4   C8x C    22.8900  -17.5000
            5   C8x C    22.8900  -16.0300
            6   C8x C    24.0800  -15.3300
            7   C1b C    26.5300  -15.3300
            8   C1c C    27.7200  -16.0300
            9   C6a C    28.9100  -15.3300
            10  O6a O    30.1000  -16.0300
            11  O6a O    28.9100  -13.9300
            12  N1a N    27.7200  -17.5000
BOND        12
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    9  11 2
            12    8  12 1 #Up

» Japanese version

KEGG   COMPOUND: C00078
Entry
C00078                      Compound                               

Name
L-Tryptophan;
Tryptophan;
(S)-alpha-Amino-beta-(3-indolyl)-propionic acid
Formula
C11H12N2O2
Exact mass
204.0899
Mol weight
204.2252
Structure
Remark
Same as: D00020
Reaction
Pathway
map00260  Glycine, serine and threonine metabolism
map00380  Tryptophan metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00404  Staurosporine biosynthesis
map00901  Indole alkaloid biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00998  Biosynthesis of various secondary metabolites - part 2
map01060  Biosynthesis of plant secondary metabolites
map01061  Biosynthesis of phenylpropanoids
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map04361  Axon regeneration
map04726  Serotonergic synapse
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05143  African trypanosomiasis
map05230  Central carbon metabolism in cancer
Module
M00023  Tryptophan biosynthesis, chorismate => tryptophan
M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin
M00786  Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
M00789  Rebeccamycin biosynthesis, tryptophan => rebeccamycin
M00790  Pyrrolnitrin biosynthesis, tryptophan => pyrrolnitrin
M00805  Staurosporine biosynthesis, tryptophan => staurosporine
M00808  Violacein biosynthesis, tryptophan => violacein
M00891  Ditryptophenaline biosynthesis, tryptophan + phenylalanine => ditryptophenaline
M00901  Fumiquinazoline biosynthesis, tryptophan + alanine + anthranilate => fumiquinazoline
M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
M00936  Melatonin biosynthesis, plants, tryptophan => serotonin => melatonin
Enzyme
1.3.3.10        1.4.1.19        1.4.3.2         1.4.3.-         
1.13.11.11      1.13.11.52      1.13.12.3       1.13.99.3       
1.14.14.156     1.14.16.4       1.14.19.9       1.14.19.58      
1.14.19.59      2.1.1.106       2.5.1.34        2.5.1.80        
2.6.1.27        2.6.1.28        2.6.1.99        2.6.1.-         
3.5.1.57        4.1.1.28        4.1.1.105       4.1.99.1        
4.1.99.25       4.2.1.20        4.2.1.122       4.3.1.31        
6.1.1.2         6.3.2.-
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00078  Tryptophan (Trp)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX02 Tryptophan
      D00020  Tryptophan (USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Tryptophan
    D00020  Tryptophan (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00020  L-Tryptophan
Other DBs
CAS: 73-22-3
PubChem: 3378
ChEBI: 16828
ChEMBL: CHEMBL54976
KNApSAcK: C00001396
PDB-CCD: TRP[PDBj]
3DMET: B01150
NIKKAJI: J9.181B
KCF data

ATOM        15
            1   C8y C    17.0958  -16.0419
            2   C8y C    18.4268  -16.3221
            3   C8y C    16.3953  -17.2327
            4   C8x C    16.3953  -14.7810
            5   C1b C    19.4775  -15.4815
            6   N4x N    17.2359  -18.2835
            7   C8x C    14.9243  -17.2327
            8   C8x C    14.9943  -14.7810
            9   C1c C    20.7384  -16.1120
            10  C8x C    14.2238  -16.0419
            11  N1a N    20.7384  -17.5830
            12  C6a C    21.9292  -15.4815
            13  O6a O    23.1201  -16.1820
            14  O6a O    21.9292  -14.0805
            15  C8x C    18.4268  -17.7221
BOND        16
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     7  10 2
            10    9  11 1 #Up
            11    9  12 1
            12   12  13 1
            13   12  14 2
            14    8  10 1
            15    2  15 2
            16   15   6 1

» Japanese version

KEGG   COMPOUND: C00065
Entry
C00065                      Compound                               

Name
L-Serine;
L-2-Amino-3-hydroxypropionic acid;
L-3-Hydroxy-alanine;
Serine
Formula
C3H7NO3
Exact mass
105.0426
Mol weight
105.0926
Structure
Remark
Same as: D00016
Reaction
Pathway
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00270  Cysteine and methionine metabolism
map00460  Cyanoamino acid metabolism
map00600  Sphingolipid metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00680  Methane metabolism
map00920  Sulfur metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01502  Vancomycin resistance
map02010  ABC transporters
map04071  Sphingolipid signaling pathway
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00020  Serine biosynthesis, glycerate-3P => serine
M00021  Cysteine biosynthesis, serine => cysteine
M00035  Methionine degradation
M00094  Ceramide biosynthesis
M00338  Cysteine biosynthesis, homocysteine + serine => cysteine
M00346  Formaldehyde assimilation, serine pathway
M00532  Photorespiration
M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
M00875  Staphyloferrin B biosynthesis, L-serine => staphyloferrin B
Enzyme
1.1.1.276       1.1.1.387       1.4.1.7         2.1.2.1         
2.3.1.30        2.3.1.50        2.6.1.45        2.6.1.51        
2.7.1.80        2.7.1.225       2.7.1.226       2.7.8.4         
2.7.8.8         2.7.8.29        2.7.8.38        2.8.1.4         
3.1.3.3         3.1.4.13        3.5.1.61        4.2.1.20        
4.2.1.22        4.2.1.50        4.2.1.122       4.3.1.17        
4.3.1.19        5.1.1.10        5.1.1.18        6.1.1.11        
6.3.2.14
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00065  Serine (Ser)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00016  L-Serine
Other DBs
CAS: 56-45-1
PubChem: 3365
ChEBI: 17115
ChEMBL: CHEMBL11298
KNApSAcK: C00001393
PDB-CCD: SER[PDBj]
3DMET: B01145
NIKKAJI: J1.195I
KCF data

ATOM        7
            1   C1c C    23.5961  -17.5357
            2   C6a C    22.4445  -16.7873
            3   C1b C    24.8238  -16.8518
            4   N1a N    23.6370  -18.9388
            5   O6a O    21.2226  -17.4714
            6   O6a O    22.4677  -15.3785
            7   O1a O    26.0339  -17.5708
BOND        6
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 2
            6     3   7 1

» Japanese version

KEGG   COMPOUND: C00188
Entry
C00188                      Compound                               

Name
L-Threonine;
2-Amino-3-hydroxybutyric acid
Formula
C4H9NO3
Exact mass
119.0582
Mol weight
119.1192
Structure
Remark
Same as: D00041
Reaction
Pathway
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00290  Valine, leucine and isoleucine biosynthesis
map00860  Porphyrin and chlorophyll metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map04978  Mineral absorption
Module
M00018  Threonine biosynthesis, aspartate => homoserine => threonine
M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Enzyme
1.1.1.103       2.2.1.8         2.7.1.177       2.7.7.87        
3.4.-.-         4.1.2.5         4.1.2.48        4.2.3.1         
4.3.1.19        5.1.1.6         6.1.1.3         6.3.2.-
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00188  Threonine (Thr)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Threonine
    D00041  Threonine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00041  L-Threonine
Other DBs
CAS: 72-19-5
PubChem: 3488
ChEBI: 16857
ChEMBL: CHEMBL291747
KNApSAcK: C00001394
PDB-CCD: THR[PDBj]
3DMET: B01182
NIKKAJI: J21.883I
KCF data

ATOM        8
            1   O6a O    22.5407  -18.2704
            2   C6a C    23.7531  -17.5704
            3   C1c C    24.9657  -18.2704
            4   C1c C    26.1781  -17.5704
            5   C1a C    27.3906  -18.2704
            6   O6a O    23.7531  -16.1705
            7   N1a N    24.9657  -19.6703
            8   O1a O    26.1781  -16.1703
BOND        7
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     2   6 2
            6     3   7 1 #Down
            7     4   8 1 #Down

» Japanese version

KEGG   COMPOUND: C00152
Entry
C00152                      Compound                               

Name
L-Asparagine;
2-Aminosuccinamic acid
Formula
C4H8N2O3
Exact mass
132.0535
Mol weight
132.1179
Structure
Remark
Drug group: DG01672
Reaction
Pathway
map00250  Alanine, aspartate and glutamate metabolism
map00460  Cyanoamino acid metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Enzyme
1.14.11.39      2.3.2.7         2.6.1.14        3.2.2.11        
3.5.1.1         3.5.1.38        3.5.5.4         4.2.1.65        
6.1.1.22        6.3.1.1         6.3.1.4         6.3.5.4
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00152  Asparagine (Asn)
Other DBs
CAS: 70-47-3
PubChem: 3452
ChEBI: 17196
ChEMBL: CHEMBL58832
KNApSAcK: C00001341 C00034027
PDB-CCD: 41Q[PDBj] ASN[PDBj]
3DMET: B00043
NIKKAJI: J9.178B
KCF data

ATOM        9
            1   C1c C    17.9993  -16.4694
            2   C1b C    19.1857  -15.8412
            3   C5a C    20.3722  -16.4694
            4   N1a N    21.6983  -15.8412
            5   O5a O    20.3720  -17.9349
            6   C6a C    16.8128  -15.8412
            7   O6a O    15.6264  -16.5390
            8   O6a O    16.8128  -14.4454
            9   N1a N    17.9993  -17.9349
BOND        8
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 2
            5     1   6 1
            6     6   7 1
            7     6   8 2
            8     1   9 1 #Down

» Japanese version

KEGG   COMPOUND: C00064
Entry
C00064                      Compound                               

Name
L-Glutamine;
L-2-Aminoglutaramic acid
Formula
C5H10N2O3
Exact mass
146.0691
Mol weight
146.1445
Structure
Remark
Same as: D00015
Reaction
Pathway
map00220  Arginine biosynthesis
map00230  Purine metabolism
map00240  Pyrimidine metabolism
map00250  Alanine, aspartate and glutamate metabolism
map00471  D-Glutamine and D-glutamate metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00750  Vitamin B6 metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
M00051  Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
M00916  Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
Enzyme
1.4.1.13        1.4.1.14        1.4.7.1         2.3.1.14        
2.3.1.68        2.3.2.1         2.3.2.14        2.4.2.14        
2.6.1.15        2.6.1.16        2.6.1.50        2.6.1.64        
2.6.1.85        2.6.1.86        2.6.1.100       2.6.1.101       
2.6.1.117       2.7.3.13        3.5.1.2         3.5.1.38        
3.5.1.133       4.1.3.27        4.3.2.10        4.3.3.6         
5.1.1.10        6.1.1.18        6.3.1.2         6.3.4.2         
6.3.5.1         6.3.5.2         6.3.5.3         6.3.5.4         
6.3.5.5         6.3.5.6         6.3.5.7         6.3.5.9         
6.3.5.10        6.3.5.11        6.3.5.12        6.3.5.13        
6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00064  Glutamine (Gln)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AA Amino acids and derivatives
     A16AA03 Glutamine
      D00015  Glutamine (USP) <JP/US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Gastrointestinal Agents, Other
   Short Bowel Syndrome Agents
    Glutamine
     D00015  Glutamine (USP)
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Glutamine
   D00015  Glutamine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2322  Glutamines
     D00015  Glutamine (USP); L-Glutamine (JP17)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Glutamine
    D00015  Glutamine (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00015  L-Glutamine
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00015
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00015
Other DBs
CAS: 56-85-9
PubChem: 3364
ChEBI: 18050
ChEMBL: CHEMBL930
KNApSAcK: C00001359
PDB-CCD: GLN[PDBj]
3DMET: B00017
NIKKAJI: J9.170G
KCF data

ATOM        10
            1   C1c C    23.8378  -17.4606
            2   C1b C    25.0254  -16.7178
            3   C6a C    22.6035  -16.7995
            4   N1a N    23.8787  -18.8587
            5   C1b C    26.2597  -17.3787
            6   O6a O    21.4451  -17.5952
            7   O6a O    22.6209  -15.4015
            8   C5a C    27.4472  -16.6416
            9   N1a N    28.6814  -17.3027
            10  O5a O    27.4704  -15.2435
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

» Japanese version

KEGG   COMPOUND: C00062
Entry
C00062                      Compound                               

Name
L-Arginine;
(S)-2-Amino-5-guanidinovaleric acid;
L-Arg
Formula
C6H14N4O2
Exact mass
174.1117
Mol weight
174.201
Structure
Remark
Same as: D02982
Reaction
Pathway
map00220  Arginine biosynthesis
map00261  Monobactam biosynthesis
map00330  Arginine and proline metabolism
map00331  Clavulanic acid biosynthesis
map00472  D-Arginine and D-ornithine metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04150  mTOR signaling pathway
map04974  Protein digestion and absorption
map05014  Amyotrophic lateral sclerosis
map05022  Pathways of neurodegeneration - multiple diseases
map05142  Chagas disease
map05146  Amoebiasis
map05230  Central carbon metabolism in cancer
Module
M00029  Urea cycle
M00047  Creatine pathway
M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
M00134  Polyamine biosynthesis, arginine => ornithine => putrescine
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
M00844  Arginine biosynthesis, ornithine => arginine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00879  Arginine succinyltransferase pathway, arginine => glutamate
Enzyme
1.4.1.25        1.4.3.25        1.5.1.11        1.5.1.19        
1.13.12.1       1.14.11.41      1.14.13.39      1.14.14.47      
1.14.20.7       2.1.4.1         2.1.4.2         2.1.4.3         
2.3.1.109       2.5.1.66        2.6.1.84        2.7.3.3         
3.2.2.19        3.5.3.1         3.5.3.6         4.1.1.19        
4.3.2.1         5.1.1.9         6.1.1.19        6.2.1.63        
6.3.2.11        6.3.2.24        6.3.2.30        6.3.2.48
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00062  Arginine (Arg)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Arginine
    D02982  Arginine (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02982  L-Arginine
Other DBs
CAS: 74-79-3
PubChem: 3362
ChEBI: 16467
ChEMBL: CHEMBL1485
KNApSAcK: C00001340
PDB-CCD: ARG[PDBj] GND[PDBj]
3DMET: B01143
NIKKAJI: J9.182K
KCF data

ATOM        12
            1   C1b C    24.1085  -18.0306
            2   C1b C    25.3110  -18.7488
            3   C1c C    22.8766  -18.7137
            4   C1b C    26.5369  -18.0657
            5   C6a C    21.7324  -17.9664
            6   N1a N    22.9232  -20.1148
            7   N1b N    27.7453  -18.7779
            8   O6a O    20.5065  -18.6494
            9   O6a O    21.6856  -16.5596
            10  C2c C    28.9714  -18.1007
            11  N1a N    30.1739  -18.8129
            12  N2a N    28.9888  -16.6938
BOND        11
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1 #Down
            6     4   7 1
            7     5   8 1
            8     5   9 2
            9     7  10 1
            10   10  11 1
            11   10  12 2

» Japanese version

KEGG   COMPOUND: C00135
Entry
C00135                      Compound                               

Name
L-Histidine;
(S)-alpha-Amino-1H-imidazole-4-propionic acid
Formula
C6H9N3O2
Exact mass
155.0695
Mol weight
155.1546
Structure
Remark
Same as: D00032
Reaction
Pathway
map00340  Histidine metabolism
map00404  Staurosporine biosynthesis
map00410  beta-Alanine metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map05230  Central carbon metabolism in cancer
Module
M00026  Histidine biosynthesis, PRPP => histidine
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
Enzyme
1.1.1.23        1.14.99.52      2.1.1.44        2.1.1.-         
2.3.1.33        2.6.1.38        3.4.13.18       3.4.13.20       
4.1.1.22        4.3.1.3         5.1.1.24        6.1.1.21        
6.3.2.11        6.3.2.-
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00135  Histidine (His)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Histidine
    D00032  Histidine (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00032  L-Histidine
  D00032  L-Histidine hydrochloride hydrate
Other DBs
CAS: 71-00-1
PubChem: 3435
ChEBI: 15971
ChEMBL: CHEMBL17962
KNApSAcK: C00001363
PDB-CCD: HIS[PDBj]
3DMET: B01171
NIKKAJI: J4.881J
KCF data

ATOM        11
            1   C8x C    24.1997  -18.0246
            2   N5x N    24.6612  -19.3463
            3   C8y C    26.0609  -19.3157
            4   C8x C    26.4644  -17.9751
            5   N4x N    25.3141  -17.1771
            6   C1b C    27.2524  -20.0200
            7   C1c C    28.4649  -19.3200
            8   C6a C    29.6773  -20.0200
            9   O6a O    30.8897  -19.3200
            10  O6a O    29.6773  -21.4200
            11  N1a N    28.4649  -17.9202
BOND        11
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     1   5 1
            6     3   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    8  10 2
            11    7  11 1 #Down

» Japanese version

KEGG   COMPOUND: C00047
Entry
C00047                      Compound                               

Name
L-Lysine;
Lysine acid;
2,6-Diaminohexanoic acid
Formula
C6H14N2O2
Exact mass
146.1055
Mol weight
146.1876
Structure
Remark
Same as: D02304
Reaction
Pathway
map00300  Lysine biosynthesis
map00310  Lysine degradation
map00780  Biotin metabolism
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
M00906  Ethynylserine biosynthesis, lysine => ethynylserine
M00918  Aerobactin biosynthesis, lysine => aerobactin
Enzyme
1.4.1.15        1.4.1.18        1.4.3.14        1.4.3.20        
1.5.1.7         1.5.1.8         1.5.1.16        1.5.3.4         
1.13.12.2       1.14.13.59      1.14.20.-       2.1.3.8         
2.1.4.3         2.3.1.32        2.3.1.-         2.6.1.36        
2.6.1.71        2.6.1.105       3.4.13.4        3.4.14.13       
3.5.1.12        3.5.1.17        3.5.1.130       3.5.1.-         
3.5.2.11        3.5.-.-         4.1.1.18        4.1.1.20        
4.3.1.28        4.3.2.8         5.1.1.5         5.1.1.9         
5.4.3.2         5.4.99.58       6.1.1.6         6.3.2.7         
6.3.2.11        6.3.2.20        6.3.2.-         6.3.4.19
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00047  Lysine (Lys)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05X I.V. SOLUTION ADDITIVES
    B05XB Amino acids
     B05XB03 Lysine
      D02304  Lysine (USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Lysine
    D02304  Lysine (USAN/INN)
Other DBs
CAS: 56-87-1
PubChem: 3349
ChEBI: 18019
ChEMBL: CHEMBL8085
KNApSAcK: C00001378
PDB-CCD: LYS[PDBj]
3DMET: B00013
NIKKAJI: J9.176F
KCF data

ATOM        10
            1   C1c C    29.3300  -16.8700
            2   C1b C    28.1400  -16.1700
            3   C6a C    30.5200  -16.1000
            4   N1a N    29.3300  -18.2700
            5   C1b C    26.9500  -16.8700
            6   O6a O    31.7100  -16.8000
            7   O6a O    30.5200  -14.7000
            8   C1b C    25.6900  -16.2400
            9   C1b C    24.5000  -16.9400
            10  N1a N    23.2400  -16.2400
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     9  10 1

» Japanese version

KEGG   COMPOUND: C00049
Entry
C00049                      Compound                               

Name
L-Aspartate;
L-Aspartic acid;
2-Aminosuccinic acid;
L-Asp
Formula
C4H7NO4
Exact mass
133.0375
Mol weight
133.1027
Structure
Remark
Same as: D00013
Reaction
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00270  Cysteine and methionine metabolism
map00300  Lysine biosynthesis
map00340  Histidine metabolism
map00410  beta-Alanine metabolism
map00460  Cyanoamino acid metabolism
map00710  Carbon fixation in photosynthetic organisms
map00760  Nicotinate and nicotinamide metabolism
map00770  Pantothenate and CoA biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01070  Biosynthesis of plant hormones
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map02030  Bacterial chemotaxis
map04080  Neuroactive ligand-receptor interaction
map04974  Protein digestion and absorption
map05230  Central carbon metabolism in cancer
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00017  Methionine biosynthesis, apartate => homoserine => methionine
M00018  Threonine biosynthesis, aspartate => homoserine => threonine
M00029  Urea cycle
M00033  Ectoine biosynthesis, aspartate => ectoine
M00115  NAD biosynthesis, aspartate => quinolinate => NAD
M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00170  C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
M00844  Arginine biosynthesis, ornithine => arginine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00919  Ectoine degradation, ectoine => aspartate
Enzyme
1.2.1.-         1.4.1.21        1.4.3.2         1.4.3.16        
2.1.3.2         2.3.1.17        2.6.1.1         2.6.1.12        
2.6.1.31        2.6.1.35        2.6.1.57        2.6.1.70        
2.6.1.78        2.6.1.-         2.7.2.4         3.5.1.1         
3.5.1.7         3.5.1.8         3.5.1.15        3.5.1.26        
3.5.1.38        3.5.1.134       3.5.3.14        3.5.5.4         
4.1.1.11        4.1.1.12        4.1.1.15        4.3.1.1         
5.1.1.13        6.1.1.12        6.1.1.23        6.3.1.1         
6.3.1.4         6.3.2.6         6.3.2.29        6.3.4.4         
6.3.4.5         6.3.5.4
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00049  Aspartic acid (Asp)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00049  Aspartate
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Aspartic acid
    D00013  Aspartic acid (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00013  L-Aspartic acid
Other DBs
CAS: 56-84-8
PubChem: 3351
ChEBI: 17053
ChEMBL: CHEMBL274323
KNApSAcK: C00001342
PDB-CCD: ASP[PDBj] IAS[PDBj]
3DMET: B00015
NIKKAJI: J9.169C
KCF data

ATOM        9
            1   O6a O    29.0500  -17.5000
            2   C6a C    30.2400  -16.8000
            3   C1c C    31.5000  -17.5000
            4   C1b C    32.6900  -16.8000
            5   C6a C    33.8800  -17.5000
            6   O6a O    35.1400  -16.8000
            7   O6a O    30.2400  -15.4000
            8   N1a N    31.5000  -18.9000
            9   O6a O    33.8800  -18.9000
BOND        8
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     2   7 2
            7     3   8 1 #Down
            8     5   9 2

» Japanese version

KEGG   COMPOUND: C00025
Entry
C00025                      Compound                               

Name
L-Glutamate;
L-Glutamic acid;
L-Glutaminic acid;
Glutamate
Formula
C5H9NO4
Exact mass
147.0532
Mol weight
147.1293
Structure
Remark
Same as: D00007
Reaction
R00021 R00093 R00114 R00239 R00243 R00245 R00248 R00250
R00251 R00253 R00254 R00256 R00257 R00258 R00259 R00260
R00261 R00262 R00263 R00355 R00372 R00411 R00457 R00494
R00525 R00573 R00575 R00578 R00609 R00667 R00668 R00684
R00694 R00707 R00708 R00734 R00768 R00894 R00895 R00908
R00942 R00986 R01072 R01090 R01155 R01161 R01214 R01231
R01339 R01585 R01586 R01648 R01654 R01684 R01716 R01939
R01956 R02040 R02077 R02199 R02237 R02274 R02282 R02283
R02285 R02287 R02313 R02315 R02433 R02619 R02700 R02772
R02773 R02929 R02930 R03053 R03120 R03189 R03207 R03243
 » show all
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00330  Arginine and proline metabolism
map00332  Carbapenem biosynthesis
map00340  Histidine metabolism
map00430  Taurine and hypotaurine metabolism
map00471  D-Glutamine and D-glutamate metabolism
map00480  Glutathione metabolism
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00860  Porphyrin and chlorophyll metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various secondary metabolites - part 3
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map04068  FoxO signaling pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04216  Ferroptosis
map04540  Gap junction
map04713  Circadian entrainment
map04720  Long-term potentiation
map04721  Synaptic vesicle cycle
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05033  Nicotine addiction
map05034  Alcoholism
map05230  Central carbon metabolism in cancer
Module
M00015  Proline biosynthesis, glutamate => proline
M00027  GABA (gamma-Aminobutyrate) shunt
M00028  Ornithine biosynthesis, glutamate => ornithine
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
M00118  Glutathione biosynthesis, glutamate => glutathione
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00532  Photorespiration
M00740  Methylaspartate cycle
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00879  Arginine succinyltransferase pathway, arginine => glutamate
Enzyme
1.2.1.88        1.4.1.2         1.4.1.3         1.4.1.4         
1.4.1.13        1.4.1.14        1.4.3.11        1.4.7.1         
1.5.1.9         1.5.1.10        1.5.3.18        1.5.99.5        
1.14.11.76      2.1.1.21        2.1.2.5         2.3.1.1         
2.3.1.14        2.3.1.35        2.3.2.2         2.3.2.-         
2.4.2.14        2.5.1.140       2.6.1.1         2.6.1.2         
2.6.1.3         2.6.1.4         2.6.1.5         2.6.1.6         
2.6.1.7         2.6.1.8         2.6.1.9         2.6.1.11        
2.6.1.13        2.6.1.16        2.6.1.17        2.6.1.19        
2.6.1.22        2.6.1.23        2.6.1.24        2.6.1.26        
2.6.1.27        2.6.1.29        2.6.1.33        2.6.1.34        
2.6.1.36        2.6.1.38        2.6.1.39        2.6.1.40        
2.6.1.42        2.6.1.44        2.6.1.48        2.6.1.49        
2.6.1.52        2.6.1.55        2.6.1.57        2.6.1.59        
2.6.1.65        2.6.1.67        2.6.1.72        2.6.1.75        
2.6.1.76        2.6.1.79        2.6.1.80        2.6.1.81        
2.6.1.82        2.6.1.83        2.6.1.85        2.6.1.86        
2.6.1.87        2.6.1.89        2.6.1.90        2.6.1.92        
2.6.1.93        2.6.1.94        2.6.1.95        2.6.1.98        
2.6.1.102       2.6.1.103       2.6.1.104       2.6.1.106       
2.6.1.107       2.6.1.109       2.6.1.110       2.6.1.111       
2.6.1.114       2.6.1.116       2.6.1.118       2.6.1.-         
2.7.2.11        3.4.17.21       3.4.19.9        3.4.19.13       
3.4.19.14       3.4.19.16       3.5.1.2         3.5.1.38        
3.5.1.55        3.5.1.65        3.5.1.68        3.5.1.87        
3.5.1.94        3.5.1.96        3.5.1.118       3.5.1.123       
3.5.1.129       3.5.2.9         3.5.3.8         4.1.1.15        
4.1.3.27        4.2.1.168       4.3.2.10        4.3.3.6         
5.1.1.3         5.4.3.9         5.4.99.1        6.1.1.17        
6.1.1.24        6.2.1.39        6.3.1.2         6.3.1.6         
6.3.1.11        6.3.1.17        6.3.1.18        6.3.2.2         
6.3.2.12        6.3.2.17        6.3.2.18        6.3.2.31        
6.3.2.32        6.3.2.33        6.3.2.34        6.3.2.41        
6.3.2.42        6.3.2.53        6.3.2.-         6.3.4.2         
6.3.4.12        6.3.4.24        6.3.5.1         6.3.5.2         
6.3.5.3         6.3.5.4         6.3.5.5         6.3.5.6         
6.3.5.7         6.3.5.9         6.3.5.10        6.3.5.11        
6.3.5.12        6.3.5.13        6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00025  Glutamic acid (Glu)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00025  Glutamate
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Glutamic acid
    D00007  Glutamic acid (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00007  L-Glutamic acid
Other DBs
CAS: 56-86-0
PubChem: 3327
ChEBI: 16015
ChEMBL: CHEMBL575060
KNApSAcK: C00001358
PDB-CCD: GGL[PDBj] GLU[PDBj]
3DMET: B00007
NIKKAJI: J9.171E
KCF data

ATOM        10
            1   C1c C    23.8372  -17.4608
            2   C1b C    25.0252  -16.7233
            3   C6a C    22.6023  -16.7994
            4   N1a N    23.8781  -18.8595
            5   C1b C    26.2601  -17.3788
            6   O6a O    21.4434  -17.5954
            7   O6a O    22.6198  -15.4007
            8   C6a C    27.4482  -16.6414
            9   O6a O    28.6830  -17.3028
            10  O6a O    27.4714  -15.2426
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

» Japanese version

KEGG   COMPOUND: C00082
Entry
C00082                      Compound                               

Name
L-Tyrosine;
(S)-3-(p-Hydroxyphenyl)alanine;
(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid;
Tyrosine
Formula
C9H11NO3
Exact mass
181.0739
Mol weight
181.1885
Structure
Remark
Same as: D00022
Reaction
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map00261  Monobactam biosynthesis
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00401  Novobiocin biosynthesis
map00460  Cyanoamino acid metabolism
map00680  Methane metabolism
map00730  Thiamine metabolism
map00940  Phenylpropanoid biosynthesis
map00950  Isoquinoline alkaloid biosynthesis
map00965  Betalain biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00998  Biosynthesis of various secondary metabolites - part 2
map01055  Biosynthesis of vancomycin group antibiotics
map01059  Biosynthesis of enediyne antibiotics
map01060  Biosynthesis of plant secondary metabolites
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map04728  Dopaminergic synapse
map04916  Melanogenesis
map04917  Prolactin signaling pathway
map04974  Protein digestion and absorption
map05012  Parkinson disease
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05034  Alcoholism
map05230  Central carbon metabolism in cancer
Module
M00025  Tyrosine biosynthesis, chorismate => HPP => tyrosine
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00040  Tyrosine biosynthesis, chorismate => arogenate => tyrosine
M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
M00044  Tyrosine degradation, tyrosine => homogentisate
M00127  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
M00827  C-1027 beta-amino acid moiety biosynthesis, tyrosine => 3-chloro-4,5-dihydroxy-beta-phenylalanyl-PCP
M00828  Maduropeptin beta-hydroxy acid moiety biosynthesis, tyrosine => 3-(4-hydroxyphenyl)-3-oxopropanoyl-PCP
M00889  Puromycin biosynthesis, ATP => puromycin
M00935  Methanofuran biosynthesis
Enzyme
1.2.1.101       1.3.1.43        1.3.1.78        1.3.1.79        
1.4.1.20        1.4.3.2         1.10.3.1        1.11.1.8        
1.11.2.6        1.14.14.36      1.14.16.1       1.14.16.2       
1.14.18.1       1.21.1.1        2.1.1.304       2.5.1.122       
2.5.1.147       2.6.1.1         2.6.1.5         2.6.1.9         
2.6.1.57        2.6.1.58        2.6.1.103       4.1.1.25        
4.1.1.28        4.1.1.108       4.1.99.2        4.1.99.19       
4.1.99.24       4.3.1.23        4.3.1.25        5.4.3.6         
6.1.1.1         6.3.2.24        6.3.2.25
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00082  Tyrosine (Tyr)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00022  L-Tyrosine
Other DBs
CAS: 60-18-4
PubChem: 3382
ChEBI: 17895
ChEMBL: CHEMBL925
KNApSAcK: C00001397
PDB-CCD: TYR[PDBj]
3DMET: B01154
NIKKAJI: J9.173A
KCF data

ATOM        13
            1   C8y C    25.0600  -15.8200
            2   C8x C    25.0600  -17.2200
            3   C8x C    23.8700  -17.9200
            4   C8y C    22.6800  -17.2200
            5   C8x C    22.6800  -15.8200
            6   C8x C    23.8700  -15.1200
            7   C1b C    26.3200  -15.1200
            8   O1a O    21.4200  -17.9900
            9   C1c C    27.5100  -15.8200
            10  C6a C    28.7000  -15.1200
            11  O6a O    29.8900  -15.8200
            12  O6a O    28.7000  -13.7200
            13  N1a N    27.5100  -17.2200
BOND        13
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     4   8 1
            9     7   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 2
            13    9  13 1 #Up

» Japanese version

KEGG   COMPOUND: C00097
Entry
C00097                      Compound                               

Name
L-Cysteine;
L-2-Amino-3-mercaptopropionic acid
Formula
C3H7NO2S
Exact mass
121.0197
Mol weight
121.1582
Structure
Remark
Same as: D00026
Reaction
Pathway
map00260  Glycine, serine and threonine metabolism
map00270  Cysteine and methionine metabolism
map00311  Penicillin and cephalosporin biosynthesis
map00332  Carbapenem biosynthesis
map00430  Taurine and hypotaurine metabolism
map00460  Cyanoamino acid metabolism
map00480  Glutathione metabolism
map00730  Thiamine metabolism
map00770  Pantothenate and CoA biosynthesis
map00920  Sulfur metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map04122  Sulfur relay system
map04216  Ferroptosis
map04974  Protein digestion and absorption
map05230  Central carbon metabolism in cancer
Module
M00021  Cysteine biosynthesis, serine => cysteine
M00338  Cysteine biosynthesis, homocysteine + serine => cysteine
M00609  Cysteine biosynthesis, methionine => cysteine
M00672  Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Enzyme
1.8.1.6         1.8.1.9         1.8.1.10        1.8.3.5         
1.8.3.6         1.8.4.3         1.8.4.4         1.13.11.20      
1.14.14.43      1.14.14.45      1.14.99.51      1.14.99.52      
1.14.-.-        2.5.1.47        2.5.1.48        2.5.1.49        
2.5.1.65        2.6.1.1         2.6.1.3         2.8.1.4         
2.8.1.7         2.8.1.9         3.4.11.1        3.4.11.2        
3.4.11.23       3.4.13.-        3.13.1.6        4.2.1.22        
4.3.2.9         4.4.1.1         4.4.1.9         4.4.1.10        
4.4.1.13        4.4.1.28        5.1.1.10        6.1.1.16        
6.3.1.13        6.3.2.2         6.3.2.5         6.3.2.26        
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00097  Cysteine (Cys)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D00026  L-Cysteine (JP17)
Classification of Japanese OTC drugs [BR:br08313]
 Nourishing tonics and health supplements
  45 Protein and amino acid based drugs
   D00026  L-Cysteine (JP17)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Cysteine
    D00026  L-Cysteine (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00026  L-Cysteine
Other DBs
CAS: 52-90-4
PubChem: 3397
ChEBI: 17561
ChEMBL: CHEMBL863
KNApSAcK: C00001351
PDB-CCD: CYS[PDBj]
3DMET: B01159
NIKKAJI: J9.167G
KCF data

ATOM        7
            1   C1c C    24.5141  -15.4370
            2   C6a C    23.3459  -14.6895
            3   C1b C    25.7289  -14.7361
            4   N1a N    24.5609  -16.8388
            5   O6a O    22.1311  -15.3436
            6   O6a O    23.3459  -13.2877
            7   S1a S    26.9438  -15.4838
BOND        6
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 2
            6     3   7 1

» Japanese version

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