KEGG   COMPOUND: C00047Help
Entry
C00047                      Compound                               

Name
L-Lysine;
Lysine acid;
2,6-Diaminohexanoic acid
Formula
C6H14N2O2
Exact mass
146.1055
Mol weight
146.1876
Structure
Mol fileKCF fileDB search
Remark
Same as: D02304
Reaction
Pathway
map00300  Lysine biosynthesis
map00310  Lysine degradation
map00780  Biotin metabolism
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01130  Biosynthesis of antibiotics
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
Module
M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Enzyme
1.4.1.15        1.4.1.18        1.4.3.14        1.4.3.20        
1.5.1.7         1.5.1.8         1.5.1.16        1.5.3.4         
1.13.12.2       1.14.13.59      2.1.3.8         2.3.1.32        
2.3.1.-         2.6.1.36        2.6.1.71        2.6.1.105       
3.4.13.4        3.4.14.13       3.5.1.12        3.5.1.17        
3.5.1.-         3.5.2.11        3.5.-.-         4.1.1.18        
4.1.1.20        4.3.1.28        4.3.2.8         5.1.1.5         
5.1.1.9         5.4.3.2         5.4.99.58       6.1.1.6         
6.3.2.7         6.3.2.11        6.3.2.20        6.3.4.19
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00047  Lysine (Lys)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05X I.V. SOLUTION ADDITIVES
    B05XB Amino acids
     B05XB03 Lysine
      D02304  Lysine (USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Lysine
    D02304  Lysine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 56-87-1
PubChem: 3349
ChEBI: 18019
ChEMBL: CHEMBL8085
KNApSAcK: C00001378
PDB-CCD: LYS[PDBj]
3DMET: B00013
NIKKAJI: J9.176F
KCF data Show

ATOM        10
            1   C1c C    29.3300  -16.8700
            2   C1b C    28.1400  -16.1700
            3   C6a C    30.5200  -16.1000
            4   N1a N    29.3300  -18.2700
            5   C1b C    26.9500  -16.8700
            6   O6a O    31.7100  -16.8000
            7   O6a O    30.5200  -14.7000
            8   C1b C    25.6900  -16.2400
            9   C1b C    24.5000  -16.9400
            10  N1a N    23.2400  -16.2400
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     9  10 1

» Japanese version

KEGG   COMPOUND: C00062Help
Entry
C00062                      Compound                               

Name
L-Arginine;
(S)-2-Amino-5-guanidinovaleric acid;
L-Arg
Formula
C6H14N4O2
Exact mass
174.1117
Mol weight
174.201
Structure
Mol fileKCF fileDB search
Remark
Same as: D02982
Reaction
Pathway
map00220  Arginine biosynthesis
map00261  Monobactam biosynthesis
map00330  Arginine and proline metabolism
map00331  Clavulanic acid biosynthesis
map00472  D-Arginine and D-ornithine metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00999  Biosynthesis of secondary metabolites - unclassified
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01130  Biosynthesis of antibiotics
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04150  mTOR signaling pathway
map04974  Protein digestion and absorption
map05014  Amyotrophic lateral sclerosis (ALS)
map05132  Salmonella infection
map05142  Chagas disease (American trypanosomiasis)
map05146  Amoebiasis
map05230  Central carbon metabolism in cancer
Module
M00029  Urea cycle
M00047  Creatine pathway
M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
M00134  Polyamine biosynthesis, arginine => ornithine => putrescine
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
M00844  Arginine biosynthesis, ornithine => arginine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
Enzyme
1.4.1.25        1.4.3.25        1.5.1.11        1.5.1.19        
1.13.12.1       1.14.11.41      1.14.13.39      1.14.14.47      
1.14.20.7       2.1.4.1         2.1.4.2         2.3.1.109       
2.5.1.66        2.6.1.84        2.7.3.3         3.2.2.19        
3.5.3.1         3.5.3.6         4.1.1.19        4.3.2.1         
5.1.1.9         6.1.1.19        6.3.2.11        6.3.2.24        
6.3.2.30        6.3.2.48
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00062  Arginine (Arg)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Arginine
    D02982  Arginine (USP/INN)
Pharmaceutical additives in Japan [BR:br08316]
 Stabilizing agent
  D02982  [003610] L-Arginine
 Solubilizing agent
  D02982  [003610] L-Arginine
 Buffering agent
  D02982  [003610] L-Arginine
 Solubilization agent
  D02982  [003610] L-Arginine
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02982  L-Arginine
BRITE hierarchy
Other DBs
CAS: 74-79-3
PubChem: 3362
ChEBI: 16467
ChEMBL: CHEMBL1485
KNApSAcK: C00001340
PDB-CCD: ARG[PDBj] GND[PDBj]
3DMET: B01143
NIKKAJI: J9.182K
KCF data Show

ATOM        12
            1   C1b C    24.1085  -18.0306
            2   C1b C    25.3110  -18.7488
            3   C1c C    22.8766  -18.7137
            4   C1b C    26.5369  -18.0657
            5   C6a C    21.7324  -17.9664
            6   N1a N    22.9232  -20.1148
            7   N1b N    27.7453  -18.7779
            8   O6a O    20.5065  -18.6494
            9   O6a O    21.6856  -16.5596
            10  C2c C    28.9714  -18.1007
            11  N1a N    30.1739  -18.8129
            12  N2a N    28.9888  -16.6938
BOND        11
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1 #Down
            6     4   7 1
            7     5   8 1
            8     5   9 2
            9     7  10 1
            10   10  11 1
            11   10  12 2

» Japanese version

KEGG   COMPOUND: C00077Help
Entry
C00077                      Compound                               

Name
L-Ornithine;
(S)-2,5-Diaminovaleric acid;
(S)-2,5-Diaminopentanoic acid;
(S)-2,5-Diaminopentanoate
Formula
C5H12N2O2
Exact mass
132.0899
Mol weight
132.161
Structure
Mol fileKCF fileDB search
Remark
Same as: D08302
Reaction
Pathway
map00220  Arginine biosynthesis
map00330  Arginine and proline metabolism
map00472  D-Arginine and D-ornithine metabolism
map00480  Glutathione metabolism
map00999  Biosynthesis of secondary metabolites - unclassified
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01130  Biosynthesis of antibiotics
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map02010  ABC transporters
Module
M00028  Ornithine biosynthesis, glutamate => ornithine
M00029  Urea cycle
M00134  Polyamine biosynthesis, arginine => ornithine => putrescine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
M00844  Arginine biosynthesis, ornithine => arginine
Enzyme
1.5.1.24        1.14.13.195     1.14.13.196     2.1.3.3         
2.1.4.1         2.1.4.2         2.3.1.35        2.3.1.127       
2.3.2.30        2.6.1.13        3.5.1.14        3.5.1.16        
3.5.1.20        3.5.3.1         3.5.3.25        4.1.1.17        
4.3.1.12        5.1.1.9         5.1.1.10        5.1.1.12
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Other amino acids
    C00077  L-Ornithine
BRITE hierarchy
Other DBs
CAS: 70-26-8
PubChem: 3377
ChEBI: 15729
ChEMBL: CHEMBL446143
KNApSAcK: C00001384
PDB-CCD: ORN[PDBj]
3DMET: B00020
NIKKAJI: J9.177D
KCF data Show

ATOM        9
            1   C1c C    24.3902  -16.1988
            2   C6a C    23.1783  -15.5055
            3   C1b C    25.6019  -15.5055
            4   N1a N    24.3902  -17.6028
            5   O6a O    21.9609  -16.1988
            6   O6a O    23.1783  -14.1015
            7   C1b C    26.8196  -16.1988
            8   C1b C    28.0315  -15.5055
            9   N1a N    29.2491  -16.1988
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     7   8 1
            8     8   9 1

» Japanese version

KEGG   COMPOUND: C00135Help
Entry
C00135                      Compound                               

Name
L-Histidine;
(S)-alpha-Amino-1H-imidazole-4-propionic acid
Formula
C6H9N3O2
Exact mass
155.0695
Mol weight
155.1546
Structure
Mol fileKCF fileDB search
Remark
Same as: D00032
Reaction
Pathway
map00340  Histidine metabolism
map00410  beta-Alanine metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01065  Biosynthesis of alkaloids derived from histidine and purine
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
map02010  ABC transporters
map04974  Protein digestion and absorption
map05230  Central carbon metabolism in cancer
Module
M00026  Histidine biosynthesis, PRPP => histidine
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
Enzyme
1.1.1.23        1.14.99.52      2.1.1.44        2.1.1.-         
2.3.1.33        2.6.1.38        3.4.13.18       3.4.13.20       
4.1.1.22        4.3.1.3         5.1.1.24        6.1.1.21        
6.3.2.11
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00135  Histidine (His)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Histidine
    D00032  Histidine (USP/INN)
Pharmaceutical additives in Japan [BR:br08316]
 Stabilizing agent
  D00032  [003617] L-Histidine
 Buffering agent
  D00032  [003617] L-Histidine
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00032  L-Histidine
  D00032  L-Histidine hydrochloride hydrate
BRITE hierarchy
Other DBs
CAS: 71-00-1
PubChem: 3435
ChEBI: 15971
ChEMBL: CHEMBL17962
KNApSAcK: C00001363
PDB-CCD: HIS[PDBj]
3DMET: B01171
NIKKAJI: J4.881J
KCF data Show

ATOM        11
            1   C8x C    24.1997  -18.0246
            2   N5x N    24.6612  -19.3463
            3   C8y C    26.0609  -19.3157
            4   C8x C    26.4644  -17.9751
            5   N4x N    25.3141  -17.1771
            6   C1b C    27.2524  -20.0200
            7   C1c C    28.4649  -19.3200
            8   C6a C    29.6773  -20.0200
            9   O6a O    30.8897  -19.3200
            10  O6a O    29.6773  -21.4200
            11  N1a N    28.4649  -17.9202
BOND        11
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     1   5 1
            6     3   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    8  10 2
            11    7  11 1 #Down

» Japanese version

KEGG   COMPOUND: C04137Help
Entry
C04137                      Compound                               

Name
D-Octopine;
N2-(D-1-Carboxyethyl)-L-arginine;
N2-(1-Carboxyethyl)-L-arginine;
Arginine, N2-(1-carboxyethyl)-, L-;
D-(+)-Octopine;
L-Arginine, N2-(1-carboxyethyl)-, (R)-;
L-Arginine, N2-[(1R)-1-carboxyethyl]-;
Octopine
Formula
C9H18N4O4
Exact mass
246.1328
Mol weight
246.2636
Structure
Mol fileKCF fileDB search
Reaction
Pathway
map00330  Arginine and proline metabolism
map02010  ABC transporters
Enzyme
Other DBs
CAS: 34522-32-2
PubChem: 6823
ChEBI: 15805
KNApSAcK: C00001549
3DMET: B04929
NIKKAJI: J18.376H
KCF data Show

ATOM        17
            1   O6a O    19.8100  -27.5100
            2   C6a C    21.0224  -26.8100
            3   C1c C    22.2349  -27.5100
            4   C1b C    23.4473  -26.8100
            5   C1b C    24.6597  -27.5100
            6   C1b C    25.8722  -26.8100
            7   N1b N    27.0846  -27.5100
            8   C2c C    28.2970  -26.8100
            9   N1a N    29.5095  -27.5100
            10  N2a N    28.2970  -25.4101
            11  O6a O    21.0224  -25.4102
            12  N1b N    22.2349  -29.4698
            13  C1c C    21.0413  -30.1590
            14  C6a C    19.8552  -29.4742
            15  O6a O    18.6633  -30.1625
            16  C1a C    21.0411  -31.5697
            17  O6a O    19.8550  -28.4902
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 1
            8     8   9 1
            9     8  10 2
            10    2  11 2
            11    3  12 1 #Down
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   13  16 1
            16   14  17 2

» Japanese version

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