KEGG   COMPOUND: C00082
Entry
C00082                      Compound                               
Name
L-Tyrosine;
(S)-3-(p-Hydroxyphenyl)alanine;
(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid;
Tyrosine
Formula
C9H11NO3
Exact mass
181.0739
Mol weight
181.19
Structure
Remark
Same as: D00022
Reaction
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map00261  Monobactam biosynthesis
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00401  Novobiocin biosynthesis
map00460  Cyanoamino acid metabolism
map00680  Methane metabolism
map00730  Thiamine metabolism
map00940  Phenylpropanoid biosynthesis
map00950  Isoquinoline alkaloid biosynthesis
map00965  Betalain biosynthesis
map00966  Glucosinolate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various other secondary metabolites
map00998  Biosynthesis of various antibiotics
map00999  Biosynthesis of various plant secondary metabolites
map01055  Biosynthesis of vancomycin group antibiotics
map01059  Biosynthesis of enediyne antibiotics
map01060  Biosynthesis of plant secondary metabolites
map01063  Biosynthesis of alkaloids derived from shikimate pathway
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map04728  Dopaminergic synapse
map04916  Melanogenesis
map04917  Prolactin signaling pathway
map04974  Protein digestion and absorption
map05012  Parkinson disease
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05034  Alcoholism
map05230  Central carbon metabolism in cancer
Module
M00025  Tyrosine biosynthesis, chorismate => HPP => tyrosine
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00040  Tyrosine biosynthesis, chorismate => arogenate => tyrosine
M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
M00044  Tyrosine degradation, tyrosine => homogentisate
M00127  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
M00827  C-1027 beta-amino acid moiety biosynthesis, tyrosine => 3-chloro-4,5-dihydroxy-beta-phenylalanyl-PCP
M00828  Maduropeptin beta-hydroxy acid moiety biosynthesis, tyrosine => 3-(4-hydroxyphenyl)-3-oxopropanoyl-PCP
M00889  Puromycin biosynthesis, ATP => puromycin
M00935  Methanofuran biosynthesis
M00961  Betacyanin biosynthesis, L-tyrosine => amaranthin
Network
nt06016  Phenylalanine and tyrosine metabolism
nt06028  Dopamine and serotonin metabolism
nt06322  TRH-TSH-TH signaling
nt06463  Parkinson disease
Enzyme
1.2.1.101       1.3.1.43        1.3.1.78        1.3.1.79        
1.4.1.20        1.4.3.2         1.10.3.1        1.11.1.8        
1.11.2.6        1.14.14.36      1.14.16.1       1.14.16.2       
1.14.18.1       1.14.-.-        1.21.1.1        2.1.1.304       
2.5.1.122       2.5.1.147       2.6.1.1         2.6.1.5         
2.6.1.9         2.6.1.57        2.6.1.58        2.6.1.103       
4.1.1.25        4.1.1.28        4.1.1.108       4.1.99.2        
4.1.99.19       4.1.99.24       4.3.1.23        4.3.1.25        
5.4.3.6         6.1.1.1         6.3.2.24        6.3.2.25
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00082  Tyrosine (Tyr)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00022  L-Tyrosine
Other DBs
CAS: 60-18-4
PubChem: 3382
ChEBI: 17895
KNApSAcK: C00001397
PDB-CCD: TYR[PDBj]
NIKKAJI: J9.173A
KCF data

ATOM        13
            1   C8y C    25.0600  -15.8200
            2   C8x C    25.0600  -17.2200
            3   C8x C    23.8700  -17.9200
            4   C8y C    22.6800  -17.2200
            5   C8x C    22.6800  -15.8200
            6   C8x C    23.8700  -15.1200
            7   C1b C    26.3200  -15.1200
            8   O1a O    21.4200  -17.9900
            9   C1c C    27.5100  -15.8200
            10  C6a C    28.7000  -15.1200
            11  O6a O    29.8900  -15.8200
            12  O6a O    28.7000  -13.7200
            13  N1a N    27.5100  -17.2200
BOND        13
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     4   8 1
            9     7   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 2
            13    9  13 1 #Up

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