KEGG   COMPOUND: C00744Help
Entry
C00744                      Compound                               

Name
Macrocin;
Tylosin C
Formula
C45H75NO17
Exact mass
901.5035
Mol weight
902.0735
Structure
Mol fileKCF fileDB search
Sequence
0 Mtk  1 Mtd  2 Mtd  3 Man  4 Mte  5 Etk  6 Mtk  7 Man
  Gene
0-2 tylG [UP:O33954]; 3 tylG [UP:O33955]; 4-5 tylG [UP:O33956];
6 tylG [UP:O33957]; 7 tylG [UP:O33958]
  Organism
Streptomyces fradiae
  Type
PK
Reaction
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01130  Biosynthesis of antibiotics
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Enzyme
2.1.1.101       2.1.1.102
Brite
Lipids [BR:br08002]
 PK  Polyketides
  PK04 Macrolides and lactone polyketides
   C00744  Macrocin
BRITE hierarchy
Other DBs
CAS: 11049-15-3
PubChem: 4006
ChEBI: 17371
ChEMBL: CHEMBL263259
KNApSAcK: C00018716
PDB-CCD: 3ZP[PDBj]
3DMET: B01321
NIKKAJI: J147.592D
KCF data Show

ATOM        63
            1   C1y C    28.4971  -18.4932
            2   C1y C    29.6061  -19.1409
            3   O2a O    27.4932  -19.7538
            4   C1y C    28.4971  -17.2149
            5   C1y C    30.7209  -18.4932
            6   N1c N    29.6061  -20.4192
            7   C1y C    25.8764  -21.0087
            8   O2x O    29.6061  -16.5729
            9   C1a C    27.3940  -16.5729
            10  C1y C    30.7209  -17.2149
            11  O1a O    31.8356  -19.1409
            12  C1a C    28.4563  -21.5339
            13  C1a C    30.9192  -21.6858
            14  C1x C    25.8764  -22.2868
            15  O2x O    24.7500  -20.3725
            16  O2a O    32.6645  -15.2772
            17  C1z C    24.7500  -22.9347
            18  C1y C    23.6410  -21.0087
            19  C1y C    30.6741  -12.7848
            20  C1y C    23.6410  -22.2868
            21  C1a C    25.6897  -23.9444
            22  O1a O    23.8978  -24.0495
            23  C1a C    22.5437  -20.3725
            24  C1y C    30.6625  -11.4775
            25  C1y C    29.5418  -13.4561
            26  O1a O    22.5437  -22.9347
            27  C1x C    29.5243  -10.8414
            28  C1b C    31.7715  -10.8297
            29  C1y C    29.5477  -14.7752
            30  C1a C    28.5205  -12.5633
            31  C1y C    29.5243   -9.5398
            32  C4a C    32.8862  -11.4600
            33  C1x C    28.4037  -15.4348
            34  O1a O    30.6625  -15.4114
            35  C5x C    28.3979   -8.9094
            36  C1a C    30.6333   -8.9035
            37  O4a O    33.9893  -10.8121
            38  C7x C    27.2713  -14.7344
            39  C2x C    27.2889   -9.5398
            40  O5x O    28.3979   -7.6195
            41  O7x O    26.1332  -15.3938
            42  O6a O    27.3298  -13.5144
            43  C2x C    27.2889  -10.8414
            44  C1y C    25.0244  -14.7168
            45  C2y C    26.0866  -11.4775
            46  C1y C    25.0068  -13.4268
            47  C1b C    23.8803  -15.3764
            48  C2x C    26.1391  -12.7674
            49  C1a C    25.0477  -10.8414
            50  C1b C    23.8920  -12.7791
            51  C1a C    23.8746  -16.6604
            52  O2a O    22.3687  -13.9055
            53  C1y C    20.5593  -15.3121
            54  C1y C    20.5593  -16.5903
            55  O2x O    19.4505  -14.6701
            56  C1y C    19.4505  -17.2383
            57  O2a O    21.6800  -17.2383
            58  C1y C    18.3355  -15.3121
            59  C1y C    18.3355  -16.5903
            60  O1a O    19.4505  -18.5163
            61  C1a C    22.4562  -18.5106
            62  C1a C    17.2325  -14.6701
            63  O1a O    17.2325  -17.2383
BOND        66
            1     1   2 1
            2     1   3 1 #Down
            3     1   4 1
            4     2   5 1
            5     2   6 1 #Up
            6     7   3 1 #Up
            7     4   8 1
            8     4   9 1 #Up
            9     5  10 1
            10    5  11 1 #Down
            11    6  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 1
            15   10  16 1 #Up
            16   14  17 1
            17   15  18 1
            18   19  16 1 #Down
            19   17  20 1
            20   17  21 1 #Down
            21   17  22 1 #Up
            22   18  23 1 #Down
            23   19  24 1
            24   19  25 1
            25   20  26 1 #Up
            26   24  27 1
            27   24  28 1 #Down
            28   25  29 1
            29   25  30 1 #Down
            30   27  31 1
            31   28  32 1
            32   29  33 1
            33   29  34 1 #Down
            34   31  35 1
            35   31  36 1 #Down
            36   32  37 2
            37   33  38 1
            38   35  39 1
            39   35  40 2
            40   38  41 1
            41   38  42 2
            42   39  43 2
            43   41  44 1
            44   43  45 1
            45   44  46 1
            46   44  47 1 #Down
            47   45  48 2
            48   45  49 1
            49   46  50 1 #Up
            50   47  51 1
            51   50  52 1
            52   53  52 1 #Up
            53   53  54 1
            54   53  55 1
            55   54  56 1
            56   54  57 1 #Down
            57   55  58 1
            58   56  59 1
            59   56  60 1 #Down
            60   57  61 1
            61   58  62 1 #Up
            62   59  63 1 #Down
            63    8  10 1
            64   18  20 1
            65   46  48 1
            66   58  59 1

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