KEGG   COMPOUND: C05349Help
Entry
C05349                      Compound                               

Name
Ciprofloxacin
Formula
C17H18FN3O3
Exact mass
331.1332
Mol weight
331.3415
Structure
Mol fileKCF fileDB search
Remark
Same as: D00186
Pathway
map02010  ABC transporters
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA02 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE03 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN) <JP/US>
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA15 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA07 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Ciprofloxacin
    D00186  Ciprofloxacin (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D00186  Ciprofloxacin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00186  Ciprofloxacin
Antiinfectives [br08350.html]
 Antibacterials
  D00186
BRITE hierarchy
Other DBs
CAS: 85721-33-1
PubChem: 7727
ChEBI: 100241
ChEMBL: CHEMBL8
PDB-CCD: CPF[PDBj]
NIKKAJI: J21.732H
KCF data Show

ATOM        24
            1   C8y C    23.1552  -17.6571
            2   C8y C    23.1552  -19.0610
            3   C8x C    24.3486  -19.7630
            4   C8y C    25.6121  -19.0610
            5   C8y C    25.6121  -17.6571
            6   C8x C    24.3486  -16.9551
            7   N4y N    26.8054  -19.7630
            8   C8x C    27.9988  -19.0610
            9   C8y C    27.9988  -17.6571
            10  C8y C    26.8054  -16.9551
            11  N1y N    21.9619  -19.7630
            12  C1x C    20.7685  -19.0610
            13  C1x C    19.5050  -19.7630
            14  N1x N    19.5050  -21.1669
            15  C1x C    20.6983  -21.8689
            16  C1x C    21.9619  -21.1669
            17  X   F    21.9619  -16.9551
            18  O5x O    26.8054  -15.5512
            19  C6a C    29.1921  -16.9551
            20  O6a O    30.3855  -17.6571
            21  O6a O    29.1921  -15.5512
            22  C1y C    26.8054  -21.1669
            23  C1x C    27.5074  -22.3603
            24  C1x C    26.1035  -22.3603
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    2  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   11  16 1
            19    1  17 1
            20   10  18 2
            21    9  19 1
            22   19  20 1
            23   19  21 2
            24    7  22 1
            25   22  23 1
            26   22  24 1
            27   23  24 1

» Japanese version

KEGG   COMPOUND: C06687Help
Entry
C06687                      Compound                               

Name
Norfloxacin
Formula
C16H18FN3O3
Exact mass
319.1332
Mol weight
319.3308
Structure
Mol fileKCF fileDB search
Remark
Same as: D00210
Pathway
map02010  ABC transporters
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Quinolones
   Fluoroquinolones
    C06687  Norfloxacin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA06 Norfloxacin
      D00210  Norfloxacin (JP17/USP/INN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE02 Norfloxacin
      D00210  Norfloxacin (JP17/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00210  Norfloxacin (JP17/USP/INN)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D00210  Norfloxacin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00210  Norfloxacin
Antiinfectives [br08350.html]
 Antibacterials
  D00210
Animal drugs in Japan [BR:br08331]
 97  Agents against pathogenic micro-organisms and parasites (except biological products and disinfectants)
  973  Synthetic antimicrobials
   9734  Quinolone, derivatives and preparations
    C06687  Norfloxacin
BRITE hierarchy
Other DBs
CAS: 70458-96-7
PubChem: 8912
ChEBI: 100246
ChEMBL: CHEMBL9
NIKKAJI: J1.144D
KCF data Show

ATOM        23
            1   C8y C    22.6983  -16.5436
            2   C8y C    22.6983  -15.1538
            3   N4y N    23.9247  -17.2386
            4   C8x C    21.4721  -17.2386
            5   C8y C    23.9247  -14.4530
            6   C8x C    21.4721  -14.4530
            7   C8x C    25.1509  -16.5436
            8   C1b C    23.9188  -18.6458
            9   C8y C    20.2516  -16.5436
            10  C8y C    25.1509  -15.1538
            11  O5x O    23.9188  -13.0399
            12  C8y C    20.2516  -15.1538
            13  C1a C    22.7042  -19.3349
            14  N1y N    19.0428  -17.2210
            15  C6a C    26.3654  -14.4414
            16  X   F    19.0428  -14.4707
            17  C1x C    17.8398  -16.5202
            18  C1x C    19.0428  -18.6050
            19  O6a O    27.5859  -15.1421
            20  O6a O    26.3597  -13.0283
            21  C1x C    16.6370  -17.2210
            22  C1x C    17.8457  -19.2998
            23  N1x N    16.6370  -18.6108
BOND        25
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12    8  13 1
            13    9  14 1
            14   10  15 1
            15   12  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 1
            19   15  20 2
            20   17  21 1
            21   18  22 1
            22   21  23 1
            23    7  10 2
            24    9  12 1
            25   22  23 1

» Japanese version

KEGG   COMPOUND: C07663Help
Entry
C07663                      Compound                               

Name
Moxifloxacin
Formula
C21H24FN3O4
Exact mass
401.1751
Mol weight
401.4314
Structure
Mol fileKCF fileDB search
Remark
Same as: D08237
Pathway
map02010  ABC transporters
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA14 Moxifloxacin
      D08237  Moxifloxacin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE07 Moxifloxacin
      D08237  Moxifloxacin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Moxifloxacin
    D08237  Moxifloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 151096-09-2
PubChem: 9865
ChEBI: 63611
NIKKAJI: J1.495.215B
KCF data Show

ATOM        29
            1   C8y C    26.7434  -17.1440
            2   N4y N    27.9595  -17.8397
            3   C8y C    25.5333  -17.8456
            4   C8y C    26.7376  -15.7466
            5   C1y C    27.9478  -19.2429
            6   C8x C    29.1638  -17.1323
            7   C8y C    24.3231  -17.1440
            8   O2a O    25.5216  -19.2429
            9   C8y C    27.9478  -15.0393
            10  C8x C    25.5333  -15.0451
            11  C1x C    28.6377  -20.4589
            12  C1x C    27.2346  -20.4414
            13  C8y C    29.1581  -15.7349
            14  N1y N    23.1363  -18.0386
            15  C8y C    24.3231  -15.7466
            16  C1a C    24.3055  -19.9445
            17  O5x O    27.9302  -13.6478
            18  C6a C    30.3624  -15.0393
            19  C1x C    22.3002  -16.9101
            20  C1x C    22.3236  -19.1786
            21  X   F    23.1069  -15.0510
            22  O6a O    31.5668  -15.7466
            23  O6a O    30.3566  -13.6421
            24  C1y C    20.9730  -17.3604
            25  C1y C    20.9847  -18.7517
            26  C1x C    19.7628  -16.6705
            27  N1x N    19.7862  -19.4533
            28  C1x C    18.5643  -17.3778
            29  C1x C    18.5760  -18.7693
BOND        33
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 2
            10    5  11 1
            11    5  12 1
            12    6  13 2
            13    7  14 1
            14    7  15 2
            15    8  16 1
            16    9  17 2
            17   13  18 1
            18   14  19 1
            19   14  20 1
            20   15  21 1
            21   18  22 1
            22   18  23 2
            23   19  24 1
            24   20  25 1
            25   24  26 1
            26   25  27 1
            27   26  28 1
            28   27  29 1
            29    9  13 1
            30   10  15 1
            31   11  12 1
            32   24  25 1
            33   28  29 1

» Japanese version

KEGG   COMPOUND: C07662Help
Entry
C07662                      Compound                               

Name
Sparfloxacin;
cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Formula
C19H22F2N4O3
Exact mass
392.166
Mol weight
392.3998
Structure
Mol fileKCF fileDB search
Remark
Same as: D00590
Pathway
map02010  ABC transporters
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA09 Sparfloxacin
      D00590  Sparfloxacin (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 110871-86-8
PubChem: 9864
ChEBI: 9212
ChEMBL: CHEMBL850
NIKKAJI: J324.247A
KCF data Show

ATOM        28
            1   C8y C    26.0745  -16.6053
            2   C8y C    26.0745  -15.2064
            3   N4y N    27.2868  -17.3048
            4   C8y C    24.8620  -17.3048
            5   C8y C    27.2402  -14.5069
            6   C8y C    24.8620  -14.5069
            7   C1y C    27.2868  -18.7037
            8   C8x C    28.4992  -16.5587
            9   C8y C    23.6496  -16.6053
            10  X   F    24.8620  -18.7037
            11  C8y C    28.4992  -15.1598
            12  O5x O    27.2402  -13.1080
            13  C8y C    23.6496  -15.2064
            14  N1a N    24.8620  -13.1080
            15  C1x C    27.9863  -19.9162
            16  C1x C    26.5407  -19.8695
            17  C6a C    29.6650  -14.4603
            18  X   F    22.4372  -14.5069
            19  O6a O    30.8774  -15.2064
            20  O6a O    29.6650  -13.0614
            21  N1y N    22.4372  -17.3048
            22  C1x C    21.2248  -16.6053
            23  C1y C    20.0124  -17.3048
            24  N1x N    20.0124  -18.7037
            25  C1y C    21.2248  -19.4032
            26  C1x C    22.4372  -18.7037
            27  C1a C    21.2714  -20.8021
            28  C1a C    18.8000  -16.6053
BOND        31
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 2
            12    6  13 2
            13    6  14 1
            14    7  15 1
            15    7  16 1
            16   11  17 1
            17   13  18 1
            18   17  19 1
            19   17  20 2
            20    8  11 2
            21    9  13 1
            22   15  16 1
            23    9  21 1
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   21  26 1
            30   25  27 1 #Up
            31   23  28 1 #Up

» Japanese version

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