| Entry |
|
|---|
| Name |
Scopolamine (INN);
Transderm scop (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C17H21NO4
|
|---|
| Exact mass |
303.1471
|
|---|
| Mol weight |
303.3529
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Atropa belladonna [TAX: 33113]
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01762 Antiemetic
|
|---|
| Remark |
| Product (DG00065): | D00138<US> D02071<JP> |
|
|---|
| Efficacy |
Antiemetic, Mydriatic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A04 ANTIEMETICS AND ANTINAUSEANTS
A04A ANTIEMETICS AND ANTINAUSEANTS
A04AD Other antiemetics
A04AD01 Scopolamine
D00138 Scopolamine (INN) <US>
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CM Other hypnotics and sedatives
N05CM05 Scopolamine
D00138 Scopolamine (INN) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA02 Scopolamine
D00138 Scopolamine (INN) <US>
USP drug classification [BR:br08302]
Antiemetics
Antiemetics, Other
Scopolamine
D00138 Scopolamine (INN)
Gastrointestinal Agents
Antispasmodics, Gastrointestinal
Scopolamine
D00138 Scopolamine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Scopolamine
D00138 Scopolamine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00065 Scopolamine
D00138 Scopolamine
Gastrointestinal agent
DG01762 Antiemetic
DG00065 Scopolamine
D00138 Scopolamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00138 Scopolamine (INN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00065 Scopolamine
Gastrointestinal agent
DG01762 Antiemetic
DG00065 Scopolamine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C1y C 27.2691 -18.1297
2 C1y C 27.5838 -16.9522
3 C1y C 28.4522 -17.8207
4 O2x O 26.2433 -16.7249
5 C1y C 28.7612 -16.6375
6 N1y N 27.5314 -15.3494
7 C1x C 30.3057 -17.8264
8 C1x C 30.0493 -16.6433
9 C1a C 27.4790 -13.9915
10 C1y C 31.3199 -18.3685
11 O7a O 32.3631 -19.2836
12 C7a C 33.7631 -19.2836
13 O6a O 34.4427 -20.4609
14 C1c C 34.4721 -18.0566
15 C8y C 35.8400 -18.0572
16 C8x C 36.5407 -19.2720
17 C8x C 37.9407 -19.2726
18 C8x C 38.6412 -18.0604
19 C8x C 37.9405 -16.8456
20 C8x C 36.5405 -16.8451
21 C1b C 33.7664 -16.8327
22 O1a O 34.4744 -15.6081
BOND 25
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 1
7 5 8 1
8 6 9 1
9 7 10 1
10 10 11 1 #Down
11 2 4 1
12 5 6 1
13 8 10 1
14 11 12 1
15 12 13 2
16 12 14 1
17 14 15 1
18 15 16 2
19 16 17 1
20 17 18 2
21 18 19 1
22 19 20 2
23 15 20 1
24 14 21 1 #Down
25 21 22 1
|
|---|
