| Entry |
|
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| Name |
Aztreonam (JP18/USP/INN);
Azactam (TN) |
|---|
| Product |
|
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| Generic |
|
|---|
| Formula |
C13H17N5O8S2
|
|---|
| Exact mass |
435.0519
|
|---|
| Mol weight |
435.4328
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Therapeutic category: | 6122 |
| Product (DG00589): | D00240<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Disease |
Urinary tract infections [DS: H01176] |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DF Monobactams
J01DF01 Aztreonam
D00240 Aztreonam (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Antibacterials, Other
Aztreonam
D00240 Aztreonam (JP18/USP/INN)
Respiratory Tract/Pulmonary Agents
Cystic Fibrosis Agents
Inhaled Anti-infectives
Aztreonam
D00240 Aztreonam (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
612 Acting mainly on gram-negative bacteria
6122 Monobactams
D00240 Aztreonam (JP18/USP/INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01454 Monobactam
DG00589 Aztreonam
D00240 Aztreonam
DG01804 Oxyimino beta-lactam
DG00589 Aztreonam
D00240 Aztreonam
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Monobactam
D00240 Aztreonam (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00240 Aztreonam
D00240 Aztreonam for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01454 Monobactam
DG00589 Aztreonam
DG01804 Oxyimino beta-lactam
DG00589 Aztreonam
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Monobactam
DG00589 Aztreonam
|
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| Other DBs |
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| KCF data |
ATOM 28
1 C2c C 15.4000 -22.4000
2 C5a C 16.6124 -23.1000
3 C8y C 14.1876 -23.1000
4 N1b N 17.8079 -22.4096
5 C1y C 18.9953 -23.0951
6 O5a O 16.6125 -24.4998
7 C8x C 13.0547 -22.3092
8 S2x S 11.9564 -23.1439
9 C8y C 12.4109 -24.4464
10 N5x N 13.7900 -24.4167
11 N1a N 11.6135 -25.5950 #+
12 N2b N 15.4000 -21.0000
13 O2a O 16.6124 -20.3000
14 C5x C 18.9535 -24.4990
15 N1y N 20.3512 -24.4712
16 C1y C 20.3934 -23.0735
17 S4a S 21.3599 -25.4900
18 O5x O 17.9666 -25.4763
19 C1a C 21.3655 -22.1157
20 O1d O 22.3498 -24.5001
21 O1d O 20.3699 -26.4800
22 O1d O 22.4099 -26.4700 #-
23 C1d C 16.6124 -18.9000
24 C1a C 16.6124 -17.5000
25 C1a C 15.2124 -18.9000
26 C6a C 17.9900 -18.9000
27 O6a O 18.6900 -20.1124
28 O6a O 18.6900 -17.6876
BOND 29
1 1 2 1
2 1 3 1
3 2 4 1
4 5 4 1 #Up
5 2 6 2
6 3 7 2
7 7 8 1
8 8 9 1
9 9 10 2
10 3 10 1
11 9 11 1
12 1 12 2
13 12 13 1
14 5 14 1
15 14 15 1
16 15 16 1
17 5 16 1
18 15 17 1
19 14 18 2
20 16 19 1 #Down
21 17 20 2
22 17 21 2
23 17 22 1
24 13 23 1
25 23 24 1
26 23 25 1
27 23 26 1
28 26 27 2
29 26 28 1
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