KEGG   DRUG: ChlordiazepoxideHelp
Entry
D00267                      Drug                                   

Name
Chlordiazepoxide (JP17/USP/INN);
Libritabs (TN)
Formula
C16H14ClN3O
Exact mass
299.0825
Mol weight
299.7549
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01567  GABA-A receptor agonist
 DG01914  Anxiolytics, benzodiazepine derivatives
Remark
Therapeutic category: 1124
ATC code: N05BA02
Chemical structure group: DG00908
Product (DG00908): D00267<JP> D00693<US>
Product (mixture): D10207<US>
Efficacy
Antianxiety, Minor tranquilizer, Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Drug interaction
Structure map
map07030  Anxiolytics
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA02 Chlordiazepoxide
      D00267  Chlordiazepoxide (JP17/USP/INN) <JP>
USP drug classification [BR:br08302]
 Anxiolytics
  Benzodiazepines
   Chlordiazepoxide
    D00267  Chlordiazepoxide (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D00267  Chlordiazepoxide (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00267  Chlordiazepoxide (JP17/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00267  Chlordiazepoxide
  D00267  Chlordiazepoxide tablets
  D00267  Chlordiazepoxide powder
Drug classes of therapeutic agents [br08360.html]
 Psychiatric agents
  D00267
BRITE hierarchy
Other DBs
CAS: 58-25-3
PubChem: 7847333
ChEBI: 3611
ChEMBL: CHEMBL451
DrugBank: DB00475
LigandBox: D00267
NIKKAJI: J2.332I
KCF data Show

ATOM        21
            1   C2y C    15.8134  -15.8294
            2   C8y C    14.9713  -14.7198
            3   C8y C    15.3065  -13.3630
            4   N2x N    16.5675  -12.7849
            5   N2y N    17.2192  -15.8546 #+
            6   C2y C    17.8211  -13.4072
            7   C1x C    18.1076  -14.7759
            8   C8x C    14.2994  -12.3946
            9   C8x C    12.9574  -12.7827
            10  C8y C    12.6222  -14.1395
            11  C8x C    13.6293  -15.1076
            12  C1a C    20.1966  -12.9099
            13  N1b N    18.8652  -12.4728
            14  X   Cl   11.2574  -14.5339
            15  C8y C    15.1789  -17.0791
            16  C8x C    13.7773  -17.0791
            17  O3a O    17.7925  -17.0976 #-
            18  C8x C    13.0773  -18.2916
            19  C8x C    13.7773  -19.5040
            20  C8x C    15.1789  -19.5040
            21  C8x C    15.8789  -18.2916
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 2
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13   12  13 1
            14    6  13 1
            15   10  14 1
            16    1  15 1
            17   15  16 1
            18    5  17 1
            19   16  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   15  21 2

» Japanese version   » Back

KEGG   DRUG: Chlordiazepoxide hydrochlorideHelp
Entry
D00693                      Drug                                   

Name
Chlordiazepoxide hydrochloride (JAN/USP);
Librium (TN)
Product
  Generic
CHLORDIAZEPOXIDE (DIRECT RX), CHLORDIAZEPOXIDE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CHLORDIAZEPOXIDE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CHLORDIAZEPOXIDE HYDROCHLORIDE (AvKARE), CHLORDIAZEPOXIDE HYDROCHLORIDE (Bryant Ranch Prepack), CHLORDIAZEPOXIDE HYDROCHLORIDE (Bryant Ranch Prepack), CHLORDIAZEPOXIDE HYDROCHLORIDE (Cardinal Health), CHLORDIAZEPOXIDE HYDROCHLORIDE (Clinical Solutions Wholesale), CHLORDIAZEPOXIDE HYDROCHLORIDE (Contract Pharmacy Services-PA), CHLORDIAZEPOXIDE HYDROCHLORIDE (Contract Pharmacy Services-PA), CHLORDIAZEPOXIDE HYDROCHLORIDE (Contract Pharmacy Services-PA), CHLORDIAZEPOXIDE HYDROCHLORIDE (Golden State Medical Supply), CHLORDIAZEPOXIDE HYDROCHLORIDE (Mylan Institutional), CHLORDIAZEPOXIDE HYDROCHLORIDE (NuCare Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (NuCare Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (NuCare Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (REMEDYREPACK), CHLORDIAZEPOXIDE HYDROCHLORIDE (REMEDYREPACK), CHLORDIAZEPOXIDE HYDROCHLORIDE (REMEDYREPACK), CHLORDIAZEPOXIDE HYDROCHLORIDE (Solco Healthcare US LLC), CHLORDIAZEPOXIDE HYDROCHLORIDE (TYA Pharmaceuticals), CHLORDIAZEPOXIDE HYDROCHLORIDE (Teva Pharmaceuticals USA)
Formula
C16H14ClN3O. HCl
Exact mass
335.0592
Mol weight
336.2158
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01567  GABA-A receptor agonist
 DG01914  Anxiolytics, benzodiazepine derivatives
Remark
ATC code: N05BA02
Chemical structure group: DG00908
Product (DG00908): D00267<JP> D00693<US>
Product (mixture): D10247<US>
Efficacy
Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Drug interaction
Structure map
map07030  Anxiolytics
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA02 Chlordiazepoxide
      D00693  Chlordiazepoxide hydrochloride (JAN/USP) <US>
USP drug classification [BR:br08302]
 Anxiolytics
  Benzodiazepines
   Chlordiazepoxide
    D00693  Chlordiazepoxide hydrochloride (JAN/USP)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00693  Chlordiazepoxide hydrochloride (JAN/USP) <US>
Drug classes of therapeutic agents [br08360.html]
 Psychiatric agents
  D00693
BRITE hierarchy
Other DBs
CAS: 438-41-5
PubChem: 7847758
ChEBI: 3612
ChEMBL: CHEMBL1200703
DrugBank: DB00475
LigandBox: D00693
NIKKAJI: J221.151C
KCF data Show

ATOM        22
            1   C2y C    27.1723  -15.8483
            2   C8y C    26.3292  -14.7374
            3   C8y C    26.6648  -13.3790
            4   N2x N    27.9273  -12.8002
            5   N2y N    28.5798  -15.8036 #+
            6   C2y C    29.1824  -13.4232
            7   C1x C    29.4693  -14.7936
            8   C8x C    25.6565  -12.4094
            9   C8x C    24.3129  -12.7980
            10  C8y C    23.9773  -14.1564
            11  C8x C    24.9856  -15.1257
            12  C1a C    31.5608  -12.9254
            13  N1b N    30.2278  -12.4877
            14  X   Cl   22.6109  -14.5513
            15  C8y C    26.5371  -17.0995
            16  C8x C    25.1338  -17.0995
            17  O3a O    29.1538  -17.1181 #-
            18  C8x C    24.4330  -18.3135
            19  C8x C    25.1338  -19.5273
            20  C8x C    26.5371  -19.5273
            21  C8x C    27.2379  -18.3135
            22  X   Cl   31.4300  -19.0400
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 2
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13   12  13 1
            14    6  13 1
            15   10  14 1
            16    1  15 1
            17   15  16 1
            18    5  17 1
            19   16  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   15  21 2

» Japanese version   » Back

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