 | | DRUG: Cisatracurium besylate | |
| Entry |
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| Name |
Cisatracurium besylate (USP);
Cisatracurium besilate (INN);
Nimbex (TN) |
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| Product |
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| Generic |
CISATRACURIUM (Fresenius Kabi USA), CISATRACURIUM BESYLATE (Caplin Steriles Limited), CISATRACURIUM BESYLATE (Civica), CISATRACURIUM BESYLATE (Civica), CISATRACURIUM BESYLATE (Eugia US LLC), CISATRACURIUM BESYLATE (Hikma Pharmaceuticals USA), CISATRACURIUM BESYLATE (Hikma Pharmaceuticals USA), CISATRACURIUM BESYLATE (Hospira), CISATRACURIUM BESYLATE (Hospira), CISATRACURIUM BESYLATE (Meitheal Pharmaceuticals), CISATRACURIUM BESYLATE (Meitheal Pharmaceuticals), CISATRACURIUM BESYLATE (Meitheal Pharmaceuticals), CISATRACURIUM BESYLATE (PIRAMAL CRITICAL CARE), CISATRACURIUM BESYLATE (Piramal Healthcare UK Limited), CISATRACURIUM BESYLATE (Sagent Pharmaceuticals), CISATRACURIUM BESYLATE (Sandoz), CISATRACURIUM BESYLATE (Sandoz), CISATRACURIUM BESYLATE (Somerset Therapeutics), CISATRACURIUM BESYLATE (Somerset Therapeutics), CISATRACURIUM BESYLATE (Teva Parenteral Medicines), CISATRACURIUM BESYLATE (Zydus Lifesciences Limited), CISATRACURIUM BESYLATE (Zydus Lifesciences Limited), CISATRACURIUM BESYLATE (Zydus Pharmaceuticals USA), CISATRACURIUM BESYLATE (Zydus Pharmaceuticals USA) |
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| Formula |
C53H72N2O12. (C6H5O3S)2
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| Exact mass |
1242.5004
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| Mol weight |
1243.4792
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| Structure |
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| Simcomp |
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| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
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| Remark |
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| Efficacy |
Anesthetic (adjunct), Neuromuscular blocking agent |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AC Other quaternary ammonium compounds
M03AC11 Cisatracurium
D00759 Cisatracurium besylate (USP) <US>
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
D00759 Cisatracurium besylate
DG01742 Quaternary ammonium compound type muscle relaxant
D00759 Cisatracurium besylate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D00759 Cisatracurium besylate (USP) <US>
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| Other DBs |
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| KCF data |
ATOM 87
1 C8y C 14.0067 -16.1755
2 C1y C 15.2186 -16.8828
3 C8y C 14.0157 -14.7779
4 C8x C 12.8040 -16.8741
5 N2y N 16.4388 -16.1932 #+
6 C1b C 15.2186 -18.2714
7 C8x C 12.8040 -14.0706
8 C1x C 15.2362 -14.0793
9 C8y C 11.5834 -16.1755
10 C1x C 16.4478 -14.7869
11 C1b C 17.6505 -15.4765
12 C8y C 16.4301 -18.9700
13 C8y C 11.5834 -14.7779
14 O2a O 10.3806 -16.8741
15 C1b C 18.8621 -16.1755
16 C8x C 17.6328 -18.2627
17 C8x C 16.4301 -20.3673
18 O2a O 10.3806 -14.0706
19 C1a C 9.1690 -16.1755
20 C7a C 20.0739 -15.4765
21 C8y C 18.8444 -18.9613
22 C8x C 17.6418 -21.0573
23 C1a C 9.1690 -14.7692
24 O7a O 21.2765 -16.1755
25 O6a O 20.0649 -14.0706
26 C8y C 18.8534 -20.3586
27 O2a O 20.0562 -18.2537
28 C1b C 22.4882 -15.4678
29 O2a O 20.0562 -21.0486
30 C1a C 21.2589 -18.9523
31 C1b C 23.7001 -16.1665
32 C1a C 21.2589 -20.3496
33 C1b C 24.9116 -15.4588
34 C1b C 26.1232 -16.1578
35 C1b C 27.3349 -15.4501
36 O7a O 28.5465 -16.1488
37 C7a C 29.7580 -15.4414
38 C1b C 30.9697 -16.1401
39 O6a O 29.7493 -14.0439
40 C1b C 32.1813 -15.4414
41 N2y N 33.3931 -16.1401 #+
42 C1y C 34.6047 -16.8387
43 C1x C 33.3931 -14.7338
44 C1a C 32.1726 -16.8297
45 C8y C 35.8163 -16.1401
46 C1b C 34.6047 -18.2273
47 C1x C 34.6047 -14.0352
48 C8y C 35.8163 -14.7425
49 C8x C 37.0280 -16.8297
50 C8y C 33.3931 -18.9259
51 C8x C 37.0369 -14.0439
52 C8y C 38.2395 -16.1401
53 C8x C 32.1726 -18.2273
54 C8x C 33.3931 -20.3319
55 C8y C 38.2395 -14.7425
56 O2a O 39.4424 -16.8387
57 C8y C 30.9520 -18.9346
58 C8x C 32.1813 -21.0309
59 O2a O 39.4424 -14.0352
60 C1a C 40.6540 -16.1401
61 C8y C 30.9609 -20.3409
62 O2a O 29.7403 -18.2273
63 C1a C 40.6540 -14.7338
64 O2a O 29.7403 -21.0309
65 C1a C 28.5378 -18.9259
66 C1a C 28.5378 -20.3319
67 C1a C 17.6415 -16.8693
68 C8y C 12.4644 -20.8155
69 C8x C 11.2438 -21.5142
70 C8x C 13.6761 -21.5142
71 S4a S 12.4467 -19.4092
72 C8x C 11.2438 -22.9204
73 C8x C 13.6761 -22.9204
74 O1d O 11.0404 -19.4004
75 O1d O 13.8530 -19.4092
76 O1d O 12.4378 -18.0030 #-
77 C8x C 12.4644 -23.6189
78 C8y C 37.6462 -20.8936
79 C8x C 36.4257 -21.6011
80 C8x C 38.8578 -21.6011
81 S4a S 37.6285 -19.4961
82 C8x C 36.4257 -23.0074
83 C8x C 38.8578 -23.0074
84 O1d O 36.2223 -19.5574
85 O1d O 39.0348 -19.4961
86 O1d O 37.6898 -18.0901 #-
87 C8x C 37.6462 -23.6971
BOND 92
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1 #Down
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 5 11 1 #Down
11 6 12 1
12 7 13 2
13 9 14 1
14 11 15 1
15 12 16 2
16 12 17 1
17 13 18 1
18 14 19 1
19 15 20 1
20 16 21 1
21 17 22 2
22 18 23 1
23 20 24 1
24 20 25 2
25 21 26 2
26 21 27 1
27 24 28 1
28 26 29 1
29 27 30 1
30 28 31 1
31 29 32 1
32 31 33 1
33 33 34 1
34 34 35 1
35 35 36 1
36 36 37 1
37 37 38 1
38 37 39 2
39 38 40 1
40 41 40 1 #Up
41 41 42 1
42 41 43 1
43 41 44 1
44 42 45 1
45 42 46 1 #Up
46 43 47 1
47 45 48 2
48 45 49 1
49 46 50 1
50 48 51 1
51 49 52 2
52 50 53 2
53 50 54 1
54 51 55 2
55 52 56 1
56 53 57 1
57 54 58 2
58 55 59 1
59 56 60 1
60 57 61 2
61 57 62 1
62 59 63 1
63 61 64 1
64 62 65 1
65 64 66 1
66 8 10 1
67 9 13 1
68 22 26 1
69 47 48 1
70 52 55 1
71 58 61 1
72 67 5 1
73 68 69 1
74 68 70 2
75 68 71 1
76 69 72 2
77 70 73 1
78 71 74 2
79 71 75 2
80 71 76 1
81 72 77 1
82 73 77 2
83 78 79 1
84 78 80 2
85 78 81 1
86 79 82 2
87 80 83 1
88 81 84 2
89 81 85 2
90 81 86 1
91 82 87 1
92 83 87 2
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