| Entry |
|
|---|
| Name |
Desipramine hydrochloride (JAN/USP);
Norpramin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C18H22N2. HCl
|
|---|
| Exact mass |
302.155
|
|---|
| Mol weight |
302.8416
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
|---|
| Remark |
| Product (DG00927): | D00812<US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA01 Desipramine
D00812 Desipramine hydrochloride (JAN/USP) <US>
USP drug classification [BR:br08302]
Antidepressants
Tricyclics
Desipramine
D00812 Desipramine hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
D00812 Desipramine hydrochloride
DG01728 Tricyclic antidepressant
DG00927 Desipramine
D00812 Desipramine hydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
D00812 Desipramine hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D00812 Desipramine hydrochloride (JAN/USP) <US>
SLC6A4 (HTT)
D00812 Desipramine hydrochloride (JAN/USP) <US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00812
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00927 Desipramine
DG01728 Tricyclic antidepressant
DG00927 Desipramine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C1x C 12.5108 -18.1831
2 C8y C 11.6661 -17.0701
3 C8y C 12.0023 -15.7092
4 N1y N 13.2672 -15.1293
5 C1x C 13.9209 -18.2084
6 C8y C 14.5246 -15.7535
7 C8y C 14.8120 -17.1264
8 C8x C 10.9921 -14.7378
9 C8x C 9.6460 -15.1271
10 C8x C 9.3098 -16.4880
11 C8x C 10.3200 -17.4591
12 C8x C 16.1472 -17.5648
13 C8x C 17.1946 -16.6276
14 C8x C 16.9074 -15.2547
15 C8x C 15.5719 -14.8162
16 C1b C 13.2889 -13.7502
17 C1b C 14.5167 -13.0670
18 C1b C 15.6886 -13.7686
19 N1b N 16.9145 -13.0865
20 C1a C 18.1530 -13.8273
21 X Cl 20.1707 -16.3481
BOND 22
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
|
|---|
