 | | DRUG: 塩酸ドキセピン | |
| エントリ |
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| 一般名 |
塩酸ドキセピン;
Doxepin hydrochloride (USP) |
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| 米国の商品 |
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| 後発品 |
DOXEPIN (Actavis Pharma), DOXEPIN (Archis Pharma LLC), DOXEPIN (Marlex Pharmaceuticals), DOXEPIN (North Star Rx LLC), DOXEPIN (REMEDYREPACK), DOXEPIN (Strides Pharma Science Limited), DOXEPIN (Zydus Lifesciences Limited), DOXEPIN (Zydus Pharmaceuticals USA), DOXEPIN HCL (Direct_Rx), DOXEPIN HCL (Direct_Rx), DOXEPIN HCL (Direct_Rx), DOXEPIN HYDROCHLORIDE (A-S Medication Solutions), DOXEPIN HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), DOXEPIN HYDROCHLORIDE (Ajanta Pharma USA), DOXEPIN HYDROCHLORIDE (Alembic Pharmaceuticals Limited), DOXEPIN HYDROCHLORIDE (Alembic Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), DOXEPIN HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), DOXEPIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), DOXEPIN HYDROCHLORIDE (Appco Pharma LLC), DOXEPIN HYDROCHLORIDE (Aurobindo Pharma Limited), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Bryant Ranch Prepack), DOXEPIN HYDROCHLORIDE (Chartwell RX), DOXEPIN HYDROCHLORIDE (Contract Pharmacal Corp.), DOXEPIN HYDROCHLORIDE (Currax Pharmaceuticals LLC dba Cypress), DOXEPIN HYDROCHLORIDE (Edenbridge Pharmaceuticals LLC.), DOXEPIN HYDROCHLORIDE (Epic Pharma), DOXEPIN HYDROCHLORIDE (First Nation Group), DOXEPIN HYDROCHLORIDE (Florida Pharmaceutical Products), DOXEPIN HYDROCHLORIDE (Golden State Medical Supply), DOXEPIN HYDROCHLORIDE (Golden State Medical Supply), DOXEPIN HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), DOXEPIN HYDROCHLORIDE (JUBILANT CADISTA PHARMACEUTICALS), DOXEPIN HYDROCHLORIDE (Lannett Company), DOXEPIN HYDROCHLORIDE (Lannett Company), DOXEPIN HYDROCHLORIDE (Leading Pharma), DOXEPIN HYDROCHLORIDE (Leading Pharma), DOXEPIN HYDROCHLORIDE (Lifestar Pharma LLC), DOXEPIN HYDROCHLORIDE (Major Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Medsource Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Medsource Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Micro Labs Limited), DOXEPIN HYDROCHLORIDE (Mylan Institutional), DOXEPIN HYDROCHLORIDE (Mylan Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Mylan Pharmaceuticals), DOXEPIN HYDROCHLORIDE (Mylan Pharmaceuticals), DOXEPIN HYDROCHLORIDE (NORTHSTAR RX LLC), DOXEPIN HYDROCHLORIDE (Novadoz Pharmaceuticals LLC), DOXEPIN HYDROCHLORIDE (Novadoz Pharmaceuticals LLC), DOXEPIN HYDROCHLORIDE (NuCare Pharmaceuticals), DOXEPIN HYDROCHLORIDE (NuCare Pharmaceuticals), DOXEPIN HYDROCHLORIDE (NuCare Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), DOXEPIN HYDROCHLORIDE (PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS), DOXEPIN HYDROCHLORIDE (Par Pharmaceutical), DOXEPIN HYDROCHLORIDE (Proficient Rx LP), DOXEPIN HYDROCHLORIDE (Proficient Rx LP), DOXEPIN HYDROCHLORIDE (Proficient Rx LP), DOXEPIN HYDROCHLORIDE (Proficient Rx LP), DOXEPIN HYDROCHLORIDE (Proficient Rx LP), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (REMEDYREPACK), DOXEPIN HYDROCHLORIDE (Rising Pharma Holdings), DOXEPIN HYDROCHLORIDE (Taro Pharmaceuticals U.S.A.), DOXEPIN HYDROCHLORIDE (Teva Pharmaceuticals USA), DOXEPIN HYDROCHLORIDE (direct rx), DOXEPIN HYDROCHLORIDE (medsource pharmaceuticals) |
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| 組成式 |
C19H21NO. HCl
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| 質量 |
315.139
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| 分子量 |
315.8371
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| 構造式 |
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| Simcomp |
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| クラス |
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| コード |
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| 効能 |
抗うつ薬, ヒスタミン受容体拮抗薬, セロトニン・ノルアドレナリン再取り込み阻害薬 |
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| ターゲット |
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| パスウェイ |
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| 代謝 |
Enzyme: CYP2C19 [HSA: 1557], CYP2D6 [HSA: 1565]; CYP1A2 [HSA: 1544], CYP2C9 [HSA: 1559]
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| 相互作用 |
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| 階層分類 |
医療用医薬品のATC分類 [BR:jp08303]
D 皮膚科用薬
D04 鎮痒薬、抗ヒスタミン薬・麻酔薬等を含む
D04A 鎮痒薬、抗ヒスタミン薬・麻酔薬等を含む
D04AX その他の鎮痒薬
D04AX01 ドキセピン
D00814 塩酸ドキセピン <US>
N 神経系
N06 精神賦活薬
N06A 抗うつ薬
N06AA 非選択的モノアミン再取り込み阻害薬
N06AA12 ドキセピン
D00814 塩酸ドキセピン <US>
医療用医薬品のUSP分類 [BR:jp08302]
抗うつ薬
三環系抗うつ薬
ドキセピン
D00814 塩酸ドキセピン
抗不安薬
抗不安薬, その他
ドキセピン
D00814 塩酸ドキセピン
皮膚科用薬
皮膚炎・そう痒治療薬
皮膚炎・そう痒治療薬, その他
ドキセピン
D00814 塩酸ドキセピン
睡眠障害治療薬
睡眠促進薬
ドキセピン
D00814 塩酸ドキセピン
医薬品グループ [BR:jp08330]
精神神経系用薬
DG01730 非選択的モノアミン再取り込み阻害薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
DG01728 三環系抗うつ薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
代謝酵素基質薬
DG01892 CYP1A2基質薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
DG01642 CYP2C9基質薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
DG01639 CYP2C19基質薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
DG01644 CYP2D6基質薬
DG00937 ドキセピン
D00814 塩酸ドキセピン
ターゲットに基づく医薬品分類 [BR:jp08310]
Gタンパク質共役受容体
ロドプシンファミリー
ヒスタミン
HRH1
D00814 塩酸ドキセピン <US>
トランスポーター
SLC ファミリー
SLC6
SLC6A2 (NAT1)
D00814 塩酸ドキセピン <US>
SLC6A4 (HTT)
D00814 塩酸ドキセピン <US>
薬物代謝酵素とトランスポーター [jp08309.html]
薬物代謝酵素
D00814
ゲノムバイオマーカー [jp08341.html]
医薬品応答に影響を与える多型と変異
D00814
医薬品グループ [BR:jp08330]
精神神経系用薬
DG01730 非選択的モノアミン再取り込み阻害薬
DG00937 ドキセピン
DG01728 三環系抗うつ薬
DG00937 ドキセピン
代謝酵素基質薬
DG01892 CYP1A2基質薬
DG00937 ドキセピン
DG01642 CYP2C9基質薬
DG00937 ドキセピン
DG01639 CYP2C19基質薬
DG00937 ドキセピン
DG01644 CYP2D6基質薬
DG00937 ドキセピン
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