KEGG   DRUG: CefmetazoleHelp
Entry
D00910                      Drug                                   

Name
Cefmetazole (USP/INN);
CMZ
Formula
C15H17N7O5S3
Exact mass
471.0453
Mol weight
471.5344
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01775  Second-generation cephalosporin
Remark
Same as: C08103
ATC code: J01DC09
Chemical structure group: DG00565
Product (DG00565): D00911<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC09 Cefmetazole
      D00910  Cefmetazole (USP/INN)
BRITE hierarchy
Other DBs
CAS: 56796-20-4
PubChem: 7847973
ChEBI: 3489
ChEMBL: CHEMBL1201195
DrugBank: DB00274
PDB-CCD: 4KO[PDBj]
LigandBox: D00910
NIKKAJI: J14.542D
KCF data Show

ATOM        30
            1   C1y C    27.9019  -15.3572
            2   N1y N    27.9019  -16.7261
            3   C2y C    29.0874  -17.4103
            4   C2y C    30.2729  -16.7261
            5   C1x C    30.2729  -15.3572
            6   S2x S    29.0874  -14.6728
            7   C1z C    26.5330  -15.3572
            8   C5x C    26.5330  -16.7261
            9   N1b N    25.3477  -14.6728
            10  C5a C    24.1622  -15.3572
            11  O5a O    24.1622  -16.7261
            12  O5x O    25.3477  -17.4103
            13  C1b C    22.9768  -14.6728
            14  C1b C    31.4764  -17.4213
            15  C6a C    29.0874  -18.7790
            16  O6a O    27.8854  -19.4731
            17  O6a O    30.2562  -19.4539
            18  S2a S    21.7722  -15.3687
            19  C1b C    20.5882  -14.6850
            20  S2a S    32.6666  -16.7343
            21  C8y C    33.8518  -17.4188
            22  N5x N    34.3167  -18.7051
            23  N5x N    35.6858  -18.6634
            24  N5x N    36.0695  -17.3486
            25  N4y N    34.9374  -16.5776
            26  O2a O    26.5330  -13.1666
            27  C1a C    27.7159  -12.4836
            28  C1a C    34.9374  -15.1836
            29  C3b C    19.3707  -15.3877
            30  N3a N    18.1623  -16.0853
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   14  20 1
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   21  25 1
            28    7  26 1 #Down
            29   26  27 1
            30   25  28 1
            31   19  29 1
            32   29  30 3

» Japanese version   » Back

KEGG   DRUG: Cefmetazole sodiumHelp
Entry
D00911                      Drug                                   

Name
Cefmetazole sodium (JP17/USP);
CMZ;
Zefazone (TN)
Formula
C15H16N7O5S3. Na
Exact mass
493.0273
Mol weight
493.5162
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01775  Second-generation cephalosporin
Remark
Same as: C08104
Therapeutic category: 6132
ATC code: J01DC09
Chemical structure group: DG00565
Product (DG00565): D00911<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC09 Cefmetazole
      D00911  Cefmetazole sodium (JP17/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00911  Cefmetazole sodium (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00911  Cefmetazole sodium
  D00911  Cefmetazole sodium for injection
Antiinfectives [br08350.html]
 Antibacterials
  D00911
BRITE hierarchy
Other DBs
CAS: 56796-39-5
PubChem: 7847974
ChEBI: 3490
ChEMBL: CHEMBL1201118
DrugBank: DB00274
LigandBox: D00911
NIKKAJI: J67.779E
KCF data Show

ATOM        31
            1   C1y C    27.8724  -15.3095
            2   N1y N    27.8724  -16.6804
            3   C2y C    29.0596  -17.3656
            4   C2y C    30.2468  -16.6804
            5   C1x C    30.2468  -15.3095
            6   S2x S    29.0596  -14.6241
            7   C1z C    26.5015  -15.3095
            8   C5x C    26.5015  -16.6804
            9   N1b N    25.3145  -14.6241
            10  C5a C    24.1273  -15.3095
            11  O5a O    24.1273  -16.6804
            12  O5x O    25.3145  -17.3656
            13  C1b C    22.9402  -14.6241
            14  C1b C    31.4521  -17.3766
            15  C6a C    29.0596  -18.7363
            16  O6a O    27.8559  -19.4314
            17  O6a O    30.2301  -19.4121 #-
            18  S2a S    21.7338  -15.3210
            19  C1b C    20.5481  -14.6363
            20  S2a S    32.6440  -16.6886
            21  C8y C    33.8309  -17.3741
            22  N5x N    34.2965  -18.6623
            23  N5x N    35.6676  -18.6905
            24  N5x N    36.0519  -17.3038
            25  N4y N    34.9181  -16.5317
            26  O2a O    26.5015  -13.1157
            27  C1a C    27.6861  -12.4317
            28  C1a C    34.9181  -15.1356
            29  C3b C    19.3288  -15.3400
            30  N3a N    18.1187  -16.0386
            31  Z   Na   31.7800  -19.3900 #+
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   14  20 1
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   21  25 1
            28    7  26 1 #Down
            29   26  27 1
            30   25  28 1
            31   19  29 1
            32   29  30 3

» Japanese version   » Back

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