| Entry |
|
|---|
| Name |
Pipamperone hydrochloride (JAN) |
|---|
| Formula |
C21H30FN3O2. 2HCl
|
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| Exact mass |
447.1856
|
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| Mol weight |
448.4021
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
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| Remark |
| Therapeutic category: | 1179 |
| Product (DG00889): | D01482<JP> |
|
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| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Butyrophenone derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07031 | Antipsychotics - butyrophenones |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD05 Pipamperone
D01482 Pipamperone hydrochloride (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D01482 Pipamperone hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00889 Pipamperone
D01482 Pipamperone hydrochloride
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00889 Pipamperone
D01482 Pipamperone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01482 Pipamperone hydrochloride (JAN) <JP>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00889 Pipamperone
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00889 Pipamperone
|
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| Other DBs |
|
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| KCF data |
ATOM 29
1 C1z C 36.3403 -17.0162
2 C1x C 35.1498 -16.3160
3 C1x C 33.8893 -17.0162
4 N1y N 33.8893 -18.4168
5 C1x C 35.1498 -19.1171
6 C1x C 36.3403 -18.4168
7 C1b C 32.6989 -19.1171
8 C1b C 31.5084 -18.4168
9 C1b C 30.2479 -19.1171
10 C5a C 29.0574 -18.4168
11 C8y C 27.8670 -19.1171
12 O5a O 29.0574 -17.0162
13 C8x C 26.6765 -18.4168
14 C8x C 25.4160 -19.1171
15 C8y C 25.4160 -20.5176
16 C8x C 26.6765 -21.2179
17 C8x C 27.8670 -20.5176
18 X F 24.2256 -21.1478
19 N1y N 37.5307 -16.3160
20 C1x C 38.7912 -17.0162
21 C1x C 39.9817 -16.3160
22 C1x C 39.9817 -14.9154
23 C1x C 38.7912 -14.2152
24 C1x C 37.5307 -14.9154
25 C5a C 37.0405 -18.2067
26 N1a N 38.4411 -18.2067
27 O5a O 36.3403 -19.3972
28 X Cl 38.2200 -21.1400
29 X Cl 38.2200 -21.1400
BOND 29
1 6 1 1
2 4 7 1
3 11 13 2
4 13 14 1
5 14 15 2
6 15 16 1
7 16 17 2
8 17 11 1
9 15 18 1
10 7 8 1
11 1 19 1
12 8 9 1
13 1 2 1
14 9 10 1
15 2 3 1
16 19 20 1
17 20 21 1
18 21 22 1
19 22 23 1
20 23 24 1
21 24 19 1
22 10 11 1
23 3 4 1
24 10 12 2
25 4 5 1
26 5 6 1
27 25 26 1
28 25 1 1
29 25 27 2
BRACKET 1 36.4700 -22.0500 36.4700 -20.3700
1 39.2000 -20.3700 39.2000 -22.0500
1 2
ORIGINAL 1 28
REPEAT 1 29
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