| Entry |
|
|---|
| Name |
Procaterol hydrochloride (USAN);
Pro-Air (TN) |
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| Formula |
C16H22N2O3. HCl
|
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| Exact mass |
326.1397
|
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| Mol weight |
326.8184
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
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| Remark |
| Product (DG01055): | D05366<JP> |
|
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| Efficacy |
Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
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| Interaction |
|
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| Structure map |
| map07214 | beta-Adrenergic receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AC Selective beta-2-adrenoreceptor agonists
R03AC16 Procaterol
D02404 Procaterol hydrochloride (USAN)
R03C ADRENERGICS FOR SYSTEMIC USE
R03CC Selective beta-2-adrenoreceptor agonists
R03CC08 Procaterol
D02404 Procaterol hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01055 Procaterol
D02404 Procaterol hydrochloride
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01055 Procaterol
D02404 Procaterol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D02404 Procaterol hydrochloride (USAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02404
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01055 Procaterol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01055 Procaterol
|
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| Other DBs |
|
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| KCF data |
ATOM 22
1 X Cl 28.2236 -18.2902
2 C8y C 18.4797 -14.4198
3 C8y C 18.4797 -15.8198
4 C8y C 19.6920 -16.5197
5 C8y C 20.9044 -15.8198
6 C8x C 20.9044 -14.4198
7 C8x C 19.6920 -13.7199
8 N4x N 17.2673 -16.5197
9 C8y C 17.2673 -17.9197
10 C8x C 18.4797 -18.6196
11 C8x C 19.6920 -17.9197
12 C1c C 22.1419 -16.5197
13 C1c C 23.3543 -15.8198
14 N1b N 24.5666 -16.5197
15 C1c C 25.7790 -15.8198
16 C1a C 26.9914 -16.5197
17 O1a O 22.1481 -17.9194
18 C1b C 23.3543 -14.4200
19 C1a C 25.7790 -14.4199
20 C1a C 22.1420 -13.7201
21 O1a O 17.2673 -13.7199
22 O5x O 16.0719 -18.6100
BOND 22
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 3 8 1
8 8 9 1
9 9 10 1
10 10 11 2
11 4 11 1
12 5 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 12 17 1
18 13 18 1
19 15 19 1
20 18 20 1
21 2 21 1
22 9 22 2
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