KEGG   DRUG: VidarabineHelp
Entry
D06298                      Drug                                   

Name
Vidarabine (JAN);
Vidarabine anhydrous;
ARA-A;
Armes (TN)
Formula
C10H13N5O4
Exact mass
267.0968
Mol weight
267.2413
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
 DG01440  Arabinofuranosyl type antiviral
Remark
Therapeutic category: 6250
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Drug interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D06298  Vidarabine (JAN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D06298  Vidarabine (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D06298  Vidarabine (JAN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  91 Antivirals
   D06298  Vidarabine (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Vidarabine
    D06298  Vidarabine (JAN)
Rx-to-OTC switch list in Japan [br08314.html]
 D06298
BRITE hierarchy
Other DBs
CAS: 5536-17-4
PubChem: 47207955
ChEMBL: CHEMBL1090 CHEMBL20247
DrugBank: DB00194
PDB-CCD: RAB[PDBj]
LigandBox: D06298
NIKKAJI: J3.415K
KCF data Show

ATOM        19
            1   N4y N    24.4593  -17.9096
            2   C8y C    25.5947  -18.7423
            3   C1y C    23.1374  -18.3465
            4   C8x C    24.8960  -16.5880
            5   C8y C    26.7243  -17.9213
            6   N5x N    25.7286  -20.1282
            7   O2x O    22.0020  -17.5196
            8   C1y C    22.6949  -19.6798
            9   N5x N    26.2992  -16.5880
            10  C8y C    27.9995  -18.4978
            11  C8x C    27.0039  -20.6989
            12  C1y C    20.8606  -18.3465
            13  C1y C    21.2972  -19.6798
            14  O1a O    23.5218  -20.8095
            15  N5x N    28.1393  -19.8896
            16  N1a N    29.1409  -17.6768
            17  C1b C    19.5272  -17.9096
            18  O1a O    20.4762  -20.8095
            19  O1a O    18.4907  -18.8531
BOND        21
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    8  14 1 #Up
            14   10  15 2
            15   10  16 1
            16   12  17 1 #Up
            17   13  18 1 #Down
            18   17  19 1
            19    5   9 1
            20   11  15 1
            21   12  13 1

» Japanese version   » Back

KEGG   DRUG: VidarabineHelp
Entry
D00406                      Drug                                   

Name
Vidarabine (USAN);
Vidarabine monohydrate;
Vira-A (TN)
Formula
C10H13N5O4. H2O
Exact mass
285.1073
Mol weight
285.2566
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
 DG01440  Arabinofuranosyl type antiviral
Remark
Same as: C07195
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Drug interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D00406  Vidarabine (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D00406  Vidarabine (USAN)
BRITE hierarchy
Other DBs
CAS: 24356-66-9
PubChem: 7847472
ChEBI: 9978
DrugBank: DB00194
LigandBox: D00406
NIKKAJI: J1.592.461F
KCF data Show

ATOM        20
            1   N4y N    24.1094  -17.9097
            2   C8y C    25.2448  -18.7424
            3   C1y C    22.7875  -18.3466
            4   C8x C    24.5461  -16.5881
            5   C8y C    26.3744  -17.9214
            6   N5x N    25.3787  -20.1283
            7   O2x O    21.6521  -17.5197
            8   C1y C    22.3450  -19.6799
            9   N5x N    25.9493  -16.5881
            10  C8y C    27.6496  -18.4979
            11  C8x C    26.6540  -20.6990
            12  C1y C    20.5107  -18.3466
            13  C1y C    20.9473  -19.6799
            14  O1a O    23.1719  -20.8096
            15  N5x N    27.7894  -19.8897
            16  N1a N    28.7910  -17.6769
            17  C1b C    19.1773  -17.9097
            18  O1a O    20.1263  -20.8096
            19  O1a O    18.1408  -18.8532
            20  O0  O    30.8800  -19.5252
BOND        21
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    8  14 1 #Up
            14   10  15 2
            15   10  16 1
            16   12  17 1 #Up
            17   13  18 1 #Down
            18   17  19 1
            19    5   9 1
            20   11  15 1
            21   12  13 1

» Japanese version   » Back

KEGG   DRUG: Vidarabine sodium phosphateHelp
Entry
D06300                      Drug                                   

Name
Vidarabine sodium phosphate (USAN)
Formula
C10H12N5O7P. 2Na
Exact mass
391.027
Mol weight
391.1849
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
 DG01440  Arabinofuranosyl type antiviral
Remark
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase ihibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Drug interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D06300  Vidarabine sodium phosphate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D06300  Vidarabine sodium phosphate (USAN)
BRITE hierarchy
Other DBs
CAS: 71002-10-3
PubChem: 47207957
ChEMBL: CHEMBL3989651
DrugBank: DB00194
LigandBox: D06300
NIKKAJI: J19.191D
KCF data Show

ATOM        25
            1   N4y N    26.9305  -17.8935
            2   C8y C    27.9744  -18.6590
            3   C1y C    25.6084  -18.3110
            4   C8x C    27.3481  -16.5017
            5   C8y C    29.1574  -17.7544
            6   N5x N    28.1135  -20.0508
            7   O2x O    24.4950  -17.4760
            8   C1y C    25.1909  -19.5636
            9   N5x N    28.8094  -16.5017
            10  C8y C    30.4100  -18.3110
            11  C8x C    29.4358  -20.6075
            12  C1y C    23.3815  -18.2415
            13  C1y C    23.7991  -19.5636
            14  N5x N    30.6188  -19.7724
            15  N1a N    31.5234  -17.4760
            16  C1b C    22.0594  -17.8239
            17  O1a O    23.3815  -20.8858
            18  O2b O    21.0155  -18.7981
            19  P1b P    19.6238  -18.7981
            20  O1c O    18.2320  -18.7981 #-
            21  O1c O    19.6238  -20.1899 #-
            22  O1c O    19.6238  -17.3368
            23  O1a O    26.0185  -20.7126
            24  Z   Na   19.2500  -21.4900 #+
            25  Z   Na   15.8900  -18.7600 #+
BOND        25
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13   10  14 2
            14   10  15 1
            15   12  16 1 #Up
            16   13  17 1 #Down
            17   16  18 1
            18   18  19 1
            19   19  20 1
            20   19  21 1
            21   19  22 2
            22    5   9 1
            23   11  14 1
            24   12  13 1
            25    8  23 1 #Up

» Japanese version   » Back

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