KEGG   DRUG: Candesartan cilexetil and anmlodipine besylateHelp
Entry
D07569            Mixture   Drug                                   

Name
Candesartan cilexetil and anmlodipine besylate (JP17);
Unisia (TN)
Component
Candesartan cilexetil [DR:D00626], Amlodipine besilate [DR:D00615]
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
Metabolizing enzyme substrate
 DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2149
ATC code: C09DB07
Product: D07569<JP>
Efficacy
Antihypertensive
Comment
Anmlodipine is metabolized by CYP3A4.
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
    C09DB Angiotensin II receptor blockers (ARBs) and calcium channel blockers
     C09DB07 Candesartan and amlodipine
      D07569  Candesartan cilexetil and anmlodipine besylate (JP17) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D07569  Candesartan cilexetil and anmlodipine besylate (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D07569  Candesartan cilexetil and anmlodipine besylate tablets
BRITE hierarchy
Other DBs
PubChem: 124490299

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