| Entry |
|
|---|
| Name |
Chlorphenoxamine hydrochloride;
Allergex (TN) |
|---|
| Formula |
C18H22ClNO. HCl
|
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| Exact mass |
339.1157
|
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| Mol weight |
340.2873
|
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| Structure |
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| Simcomp |
|
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
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| Remark |
|
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| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Diphenhydramine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA34 Chlorphenoxamine
D07684 Chlorphenoxamine hydrochloride
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA06 Chlorphenoxamine
D07684 Chlorphenoxamine hydrochloride
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00391 Chlorphenoxamine
D07684 Chlorphenoxamine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07684 Chlorphenoxamine hydrochloride
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00391 Chlorphenoxamine
|
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| Other DBs |
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| KCF data |
ATOM 22
1 X Cl 29.6101 -24.5000
2 C8x C 20.1600 -23.6600
3 C8y C 20.1600 -25.0600
4 C8x C 21.4200 -25.7600
5 C8x C 22.6100 -25.0600
6 C8y C 22.6100 -23.6600
7 C8x C 21.4200 -22.9600
8 C1d C 23.8700 -22.8900
9 C8y C 25.0600 -23.5900
10 C8x C 25.0600 -25.0600
11 C8x C 26.2500 -25.7600
12 C8x C 27.5100 -25.0600
13 C8x C 27.5100 -23.5900
14 C8x C 26.2500 -22.8900
15 O2a O 23.8700 -21.5600
16 C1b C 25.0600 -20.8600
17 C1b C 26.2500 -21.4900
18 N1c N 27.4400 -20.8600
19 C1a C 28.6300 -21.4900
20 C1a C 27.4400 -19.3900
21 C1a C 22.6100 -22.1900
22 X Cl 18.9700 -25.7600
BOND 22
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 8 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 9 14 1
15 8 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 18 20 1
21 8 21 1
22 3 22 1
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