KEGG   DRUG: PiperacillinHelp
Entry
D08380                      Drug                                   

Name
Piperacillin (INN);
PIPC;
Peracin (TN)
Formula
C23H27N5O7S
Exact mass
517.1631
Mol weight
517.5548
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
 DG01939  Acylaminopenicillin antibiotic
Remark
Same as: C14034
ATC code: J01CA12
Chemical structure group: DG00526
Product (DG00526): D00466<JP>
Product (mixture): D02505<JP/US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
map07011  Penicillins
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA12 Piperacillin
      D08380  Piperacillin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Piperacillin
    D08380  Piperacillin (INN)
BRITE hierarchy
Other DBs
CAS: 61477-96-1
PubChem: 96025066
ChEBI: 8232
ChEMBL: CHEMBL702
DrugBank: DB00319
PDB-CCD: WPP[PDBj]
LigandBox: D08380
NIKKAJI: J18.442J
KCF data Show

ATOM        36
            1   C1y C    30.1219  -18.6342
            2   C5x C    30.1219  -20.0353
            3   N1y N    31.5230  -20.0353
            4   C1y C    31.5230  -18.6342
            5   C1y C    32.8540  -20.4557
            6   C1z C    33.6947  -19.3348
            7   S2x S    32.8540  -18.2139
            8   C1a C    34.6754  -20.3156
            9   C1a C    34.6754  -18.3540
            10  C6a C    33.3444  -21.8568
            11  O6a O    34.7455  -21.8568
            12  O6a O    32.5037  -22.9776
            13  N1b N    28.9309  -17.9337
            14  C5a C    27.7400  -18.6342
            15  O5x O    28.9309  -20.7359
            16  O5a O    27.7400  -20.0353
            17  C1c C    26.4790  -17.9337
            18  C8y C    26.4790  -16.5326
            19  C8x C    27.7400  -15.8321
            20  C8x C    27.7400  -14.4310
            21  C8x C    26.4790  -13.7304
            22  C8x C    25.2881  -14.4310
            23  C8x C    25.2881  -15.8321
            24  N1b N    25.2881  -18.6342
            25  C5a C    24.0972  -17.9337
            26  O5a O    24.0972  -16.5326
            27  N1y N    22.8362  -18.6342
            28  C5x C    21.6452  -17.9337
            29  C5x C    20.3842  -18.6342
            30  N1y N    20.3842  -20.0353
            31  C1x C    21.6452  -20.7359
            32  C1x C    22.8362  -20.0353
            33  C1b C    19.1933  -20.7359
            34  C1a C    18.0024  -20.1054
            35  O5x O    19.1933  -17.9337
            36  O5x O    21.6452  -16.6027
BOND        39
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1 #Down
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   24  25 1
            27   17  24 1
            28   25  26 2
            29   25  27 1
            30   27  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   31  32 1
            35   27  32 1
            36   30  33 1
            37   33  34 1
            38   29  35 2
            39   28  36 2

» Japanese version   » Back

KEGG   DRUG: Piperacillin sodiumHelp
Entry
D00466                      Drug                                   

Name
Piperacillin sodium (JP17/USP);
Pentcillin (TN);
Pipracil (TN)
Formula
C23H26N5O7S. Na
Exact mass
539.1451
Mol weight
539.5366
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
 DG01939  Acylaminopenicillin antibiotic
Remark
Same as: C07361
Therapeutic category: 6131
ATC code: J01CA12
Chemical structure group: DG00526
Product (DG00526): D00466<JP>
Product (mixture): D02505<JP/US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
map07011  Penicillins
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA12 Piperacillin
      D00466  Piperacillin sodium (JP17/USP) <JP>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Piperacillin
    D00466  Piperacillin sodium (JP17/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D00466  Piperacillin sodium (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00466  Piperacillin sodium
  D00466  Piperacillin sodium for injection
Antiinfectives [br08350.html]
 Antibacterials
  D00466
BRITE hierarchy
Other DBs
CAS: 59703-84-3
PubChem: 7847532
ChEBI: 8233
ChEMBL: CHEMBL1200820
DrugBank: DB00319
LigandBox: D00466
NIKKAJI: J18.443H
KCF data Show

ATOM        37
            1   C1y C    29.3047  -18.6324
            2   C5x C    29.3047  -20.0318
            3   N1y N    30.7041  -20.0318
            4   C1y C    30.7041  -18.6324
            5   C1y C    32.0337  -20.4516
            6   C1z C    32.8732  -19.3322
            7   S2x S    32.0337  -18.2127
            8   C1a C    33.8528  -20.3117
            9   C1a C    33.8528  -18.3525
            10  C6a C    32.5234  -21.8509
            11  O6a O    33.9227  -21.8509 #-
            12  O6a O    31.6838  -22.9704
            13  N1b N    28.1153  -17.9328
            14  C5a C    26.9259  -18.6324
            15  O5x O    28.1153  -20.7315
            16  O5a O    26.9259  -20.0318
            17  C1c C    25.6665  -17.9328
            18  C8y C    25.6665  -16.5333
            19  C8x C    26.9259  -15.8337
            20  C8x C    26.9259  -14.4343
            21  C8x C    25.6665  -13.7345
            22  C8x C    24.4769  -14.4343
            23  C8x C    24.4769  -15.8337
            24  N1b N    24.4769  -18.6324
            25  C5a C    23.2875  -17.9328
            26  O5a O    23.2875  -16.5333
            27  N1y N    22.0424  -18.6445
            28  C5x C    20.8274  -17.9430
            29  C5x C    19.6123  -18.6445
            30  N1y N    19.6123  -20.0475
            31  C1x C    20.8274  -20.7490
            32  C1x C    22.0424  -20.0475
            33  C1b C    18.3952  -20.7501
            34  C1a C    17.2149  -20.0686
            35  O5x O    18.4141  -17.9528
            36  O5x O    20.8272  -16.5619
            37  Z   Na   35.4764  -21.8233 #+
BOND        39
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1 #Down
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   24  25 1
            27   17  24 1
            28   25  26 2
            29   25  27 1
            30   27  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   31  32 1
            35   27  32 1
            36   30  33 1
            37   33  34 1
            38   29  35 2
            39   28  36 2

» Japanese version   » Back

KEGG   DRUG: PiperacillinHelp
Entry
D02251                      Drug                                   

Name
Piperacillin (USP);
Piperacillin hydrate (JP17);
PIPC
Formula
C23H27N5O7S. H2O
Exact mass
535.1737
Mol weight
535.5701
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
 DG01939  Acylaminopenicillin antibiotic
Remark
ATC code: J01CA12
Chemical structure group: DG00526
Product (DG00526): D00466<JP>
Product (mixture): D02505<JP/US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Drug interaction
Structure map
map07011  Penicillins
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA12 Piperacillin
      D02251  Piperacillin (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Piperacillin
    D02251  Piperacillin (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02251  Piperacillin hydrate
BRITE hierarchy
Other DBs
CAS: 66258-76-2
PubChem: 7849310
DrugBank: DB00319
LigandBox: D02251
KCF data Show

ATOM        37
            1   O0  O    36.6333  -19.2267
            2   C1y C    28.1846  -18.6323
            3   C5x C    28.1846  -20.0317
            4   N1y N    29.5840  -20.0317
            5   C1y C    29.5840  -18.6323
            6   C1y C    30.9136  -20.4515
            7   C1z C    31.7531  -19.3321
            8   S2x S    30.9136  -18.2126
            9   C1a C    32.7327  -20.3116
            10  C1a C    32.7327  -18.3524
            11  C6a C    31.4033  -21.8508
            12  O6a O    32.8026  -21.8508
            13  O6a O    30.5637  -22.9703
            14  N1b N    26.9952  -17.9327
            15  C5a C    25.8058  -18.6323
            16  O5x O    26.9952  -20.7314
            17  O5a O    25.8058  -20.0317
            18  C1c C    24.5464  -17.9327
            19  C8y C    24.5464  -16.5332
            20  C8x C    25.8058  -15.8336
            21  C8x C    25.8058  -14.4343
            22  C8x C    24.5464  -13.7345
            23  C8x C    23.3568  -14.4343
            24  C8x C    23.3568  -15.8336
            25  N1b N    23.3568  -18.6323
            26  C5a C    22.1674  -17.9327
            27  O5a O    22.1674  -16.5332
            28  N1y N    20.9223  -18.6444
            29  C5x C    19.7073  -17.9429
            30  C5x C    18.4922  -18.6444
            31  N1y N    18.4922  -20.0474
            32  C1x C    19.7073  -20.7489
            33  C1x C    20.9223  -20.0474
            34  C1b C    17.2751  -20.7500
            35  C1a C    16.0948  -20.0685
            36  O5x O    17.2940  -17.9527
            37  O5x O    19.7071  -16.5618
BOND        39
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     2   5 1
            5     4   6 1
            6     6   7 1
            7     7   8 1
            8     5   8 1
            9     7   9 1
            10    7  10 1
            11    6  11 1 #Down
            12   11  12 1
            13   11  13 2
            14    2  14 1 #Up
            15   14  15 1
            16    3  16 2
            17   15  17 2
            18   15  18 1
            19   18  19 1 #Down
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   19  24 1
            26   25  26 1
            27   18  25 1
            28   26  27 2
            29   26  28 1
            30   28  29 1
            31   29  30 1
            32   30  31 1
            33   31  32 1
            34   32  33 1
            35   28  33 1
            36   31  34 1
            37   34  35 1
            38   30  36 2
            39   29  37 2

» Japanese version   » Back

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