KEGG   ENZYME: 2.3.1.42Help
Entry
EC 2.3.1.42                 Enzyme                                 

Name
glycerone-phosphate O-acyltransferase;
dihydroxyacetone phosphate acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:glycerone-phosphate O-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate [RN:R01013]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
glycerone phosphate [CPD:C00111]
Product
CoA [CPD:C00010];
acylglycerone phosphate [CPD:C03372]
Comment
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.
History
EC 2.3.1.42 created 1972
Pathway
ec00564  Glycerophospholipid metabolism
Orthology
K00649  glyceronephosphate O-acyltransferase
K13507  glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase
Genes
HSA: 8443(GNPAT)
PTR: 741681(GNPAT)
PPS: 100994430(GNPAT)
GGO: 101145496(GNPAT)
PON: 100172931(GNPAT)
NLE: 100579846(GNPAT)
MCC: 713603(GNPAT)
MCF: 101925593(GNPAT)
CSAB: 103230751(GNPAT)
RRO: 104670714(GNPAT)
RBB: 108537840(GNPAT)
CJC: 100414247(GNPAT)
SBQ: 101041808(GNPAT)
MMU: 14712(Gnpat)
MCAL: 110299645(Gnpat)
MPAH: 110337185(Gnpat)
RNO: 84470(Gnpat)
MUN: 110555322(Gnpat)
CGE: 100765024(Gnpat)
NGI: 103744131(Gnpat)
HGL: 101712069(Gnpat)
CCAN: 109694600(Gnpat)
OCU: 100353451(GNPAT)
TUP: 102468980(GNPAT)
CFA: 479204(GNPAT)
VVP: 112927336(GNPAT)
AML: 100472094(GNPAT)
UMR: 103661874(GNPAT)
UAH: 113259036(GNPAT)
ORO: 101376734(GNPAT)
ELK: 111160483
FCA: 101090468(GNPAT)
PTG: 102968870(GNPAT)
PPAD: 109248934(GNPAT)
AJU: 106981646(GNPAT)
BTA: 538800(GNPAT)
BOM: 102286073(GNPAT)
BBUB: 102402038(GNPAT)
CHX: 102174721(GNPAT)
OAS: 101111422(GNPAT)
SSC: 100156253(GNPAT)
CFR: 102522815(GNPAT)
CDK: 105102149(GNPAT)
BACU: 103006358(GNPAT)
LVE: 103085307(GNPAT)
OOR: 101283114(GNPAT)
DLE: 111163980(GNPAT)
PCAD: 102987012(GNPAT)
ECB: 100060758(GNPAT)
EPZ: 103553993(GNPAT)
EAI: 106846717(GNPAT)
MYB: 102255922(GNPAT)
MYD: 102753196(GNPAT)
MNA: 107524215(GNPAT)
HAI: 109395072(GNPAT)
DRO: 112306022(GNPAT)
PALE: 102894429(GNPAT)
RAY: 107520038(GNPAT)
MJV: 108394888(GNPAT)
LAV: 100671847(GNPAT)
TMU: 101361755
MDO: 100029521(GNPAT)
SHR: 100934097(GNPAT)
OAA: 100085042(GNPAT)
GGA: 421548(GNPAT)
MGP: 100543913(GNPAT)
CJO: 107311436(GNPAT)
NMEL: 110395420(GNPAT)
APLA: 101799745(GNPAT)
ACYG: 106044570(GNPAT)
TGU: 100224202(GNPAT)
LSR: 110468902(GNPAT)
SCAN: 103818552(GNPAT)
GFR: 102044351(GNPAT)
FAB: 101815390(GNPAT)
PHI: 102103719(GNPAT)
PMAJ: 107201920(GNPAT)
CCAE: 111927077(GNPAT)
CCW: 104684319(GNPAT)
ETL: 114064626(GNPAT)
FPG: 101921172(GNPAT)
FCH: 102049765(GNPAT)
CLV: 102090227(GNPAT)
EGZ: 104131069(GNPAT)
NNI: 104018264(GNPAT)
ACUN: 113477753(GNPAT)
PADL: 103921300(GNPAT)
AAM: 106487366(GNPAT)
ASN: 102387492(GNPAT)
AMJ: 102573444(GNPAT)
PSS: 102447254(GNPAT)
CMY: 102940346(GNPAT)
CPIC: 101948121(GNPAT)
ACS: 100562202(gnpat)
PVT: 110083064(GNPAT)
PBI: 103063911(GNPAT)
PMUR: 107290180(GNPAT)
TSR: 106538562(GNPAT)
PMUA: 114594361(GNPAT)
GJA: 107113461(GNPAT)
XLA: 100158402(gnpat.S) 108700390 444573
XTR: 100494829 733943(gnpat)
DRE: 572335(gnpat)
IPU: 108257502 108260471(gnpat)
AMEX: 103026328(gnpat) 103043282
EEE: 113568113 113577045(gnpat)
LCO: 104923569 104932463(gnpat)
NCC: 104958965(gnpat) 104962070
OLA: 101155817(gnpat) 101166180
XMA: 102217607(gnpat) 102223376
XCO: 114158931 114159119(gnpat)
PRET: 103457317(gnpat) 103457687
CVG: 107082867(gnpat) 107082868
NFU: 107377758(gnpat) 107395976
ALIM: 106520056 106530861(gnpat)
CSEM: 103381071 103381134(gnpat)
POV: 109632313 109639971(gnpat)
SDU: 111216410 111239366(gnpat)
SLAL: 111672611(gnpat) 111672757
HCQ: 109516735 109523524(gnpat)
BPEC: 110153837 110164113(gnpat)
OTW: 112239009 112250169(gnpat)
SALP: 111954372(gnpat) 112076968
ELS: 105017719(gnpat) 105017985
SFM: 108923986 108928536(gnpat)
PKI: 111836156(gnpat) 111841285
LCM: 102366515(GNPAT)
CMK: 103180557(gnpat)
RTP: 109927044(gnpat)
CIN: 100180471
SPU: 590838
APLC: 110990116
SKO: 102808986
DME: Dmel_CG4625(Dhap-at)
DER: 6554725
DSI: Dsimw501_GD18193(Dsim_GD18193)
DSR: 110191940
DPE: 6591777
DMN: 108156292
DWI: 6650388
DNV: 108660070
DHE: 111602829
MDE: 101897697
LCQ: 111679279
AAG: 5576748
AALB: 109410407
AME: 412563
BIM: 100745376
BTER: 100646321
CCAL: 108628944
OBB: 114875807
SOC: 105199621
MPHA: 105830913
AEC: 105151630
ACEP: 105617458
PBAR: 105428473
VEM: 105570218
HST: 105180680
DQU: 106742466
CFO: 105252352
LHU: 105675563
PGC: 109852203
OBO: 105286237
PCF: 106791381
NVI: 100115025
CSOL: 105362995
MDL: 103571774
TCA: 660119
DPA: 109543825
ATD: 109602862
NVL: 108560511
BMOR: 101744539
BMAN: 114250889
PMAC: 106721520
PRAP: 110993079
HAW: 110380443
TNL: 113499078
PXY: 105380393
API: 100573870
AGS: 114132563
RMD: 113558127
BTAB: 109033108
CLEC: 106666885
ZNE: 110836717
FCD: 110843586
PVM: 113821045
TUT: 107372017
CSCU: 111629040
PTEP: 107439070
CEL: CELE_Y46G5A.21(acl-7)
CBR: CBG18430(Cbr-acl-7)
BMY: Bm1_40215
PCAN: 112570166
CRG: 105348074
MYI: 110455534
EPA: 110235657
ADF: 107357049
AMIL: 114956368
PDAM: 113671924
SPIS: 111343512
DGT: 114520233
HMG: 100205381
AQU: 100640070
SCE: YBL011W(SCT1) YKR067W(GPT2)
KMX: KLMA_30247(GPT2) KLMA_30327(SCT1)
NCS: NCAS_0B06810(NCAS0B06810) NCAS_0C05390(NCAS0C05390)
NDI: NDAI_0A03280(NDAI0A03280) NDAI_0H00720(NDAI0H00720)
TPF: TPHA_0J01260(TPHA0J01260) TPHA_0K01680(TPHA0K01680)
TBL: TBLA_0C04170(TBLA0C04170) TBLA_0J00910(TBLA0J00910)
TDL: TDEL_0B02750(TDEL0B02750) TDEL_0F02510(TDEL0F02510)
KAF: KAFR_0H00490(KAFR0H00490) KAFR_0I01020(KAFR0I01020)
SLB: AWJ20_1421(SCT1)
NCR: NCU05985
NTE: NEUTE1DRAFT132129(NEUTE1DRAFT_132129)
MGR: MGG_01291
SSCK: SPSK_07062
MAW: MAC_02640
MAJ: MAA_02162
CMT: CCM_05062
MBE: MBM_01050
ANI: AN5599.2
ANG: ANI_1_490124(An14g03360)
ABE: ARB_02331
TVE: TRV_04690
PTE: PTT_06646
CNE: CNC02160
CNB: CNBC5070
ABP: AGABI1DRAFT126773(AGABI1DRAFT_126773) AGABI1DRAFT34488(AGABI1DRAFT_34488) AGABI1DRAFT61355(AGABI1DRAFT_61355)
ABV: AGABI2DRAFT117770(AGABI2DRAFT_117770) AGABI2DRAFT228041(AGABI2DRAFT_228041) AGABI2DRAFT64815(AGABI2DRAFT_64815)
MGL: MGL_2378
MRT: MRET_3273
DFA: DFA_05553
PYO: PY17X_1430600(PY06015)
PCB: PCHAS_143030(PC000822.04.0)
SMIN: v1.2.008197.t1(symbB.v1.2.008197.t1)
PTI: PHATRDRAFT_54709(GPT1)
LMA: LMJF_03_0080(GAT) LMJF_34_1090(DAT)
LIF: LINJ_03_0070(GAT) LINJ_34_1170(DAT)
 » show all
Taxonomy
Reference
1  [PMID:6271231]
  Authors
Ballas LM, Bell RM.
  Title
Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles.
  Journal
Biochim Biophys Acta 665:586-95 (1981)
DOI:10.1016/0005-2760(81)90274-5
Reference
2  [PMID:6746639]
  Authors
Declercq PE, Haagsman HP, Van Veldhoven P, Debeer LJ, Van Golde LM, Mannaerts GP.
  Title
Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.
  Journal
J Biol Chem 259:9064-75 (1984)
Reference
3  [PMID:5656381]
  Authors
Hajra AK.
  Title
Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria.
  Journal
J Biol Chem 243:3458-65 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.42
IUBMB Enzyme Nomenclature: 2.3.1.42
ExPASy - ENZYME nomenclature database: 2.3.1.42
BRENDA, the Enzyme Database: 2.3.1.42
CAS: 37257-19-5

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