KEGG   GLYCAN: G00037Help
Entry
G00037                      Glycan                                 

Name
Lc4Cer
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (Cer)1
Mass
689.6 (Cer)
Structure
KCF fileKCaMSNFG
Remark
Same as: C04910
Reaction
Pathway
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map01100  Metabolic pathways
Module
M00070  Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
Enzyme
2.4.1.65        2.4.1.69        2.4.1.86        2.4.1.87        
2.4.99.6
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0504 Galb1-3GlcNAcb1-3Galb1-4Glc- (Lacto series)
    G00037  Gal-beta1->3GlcNAc-beta-1->3Gal-beta1->4Glc-beta1->1'Cer (Lc4Cer)
BRITE hierarchy
Reference
1  [PMID:9111138]
  Authors
Henry S, Jovall PA, Ghardashkhani S, Elmgren A, Martinsson T, Larson G, Samuelsson B.
  Title
Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of a group O Le(a-b-) nonsecretor.
  Journal
Glycoconj J 14:209-23 (1997)
Reference
2  [PMID:2960671]
  Authors
Holmes EH, Hakomori S, Ostrander GK.
  Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 262:15649-58 (1987)
Other DBs
KCF data Show

NODE        5
            1   Cer        16     0
            2   Glc         7     0
            3   Gal        -1     0
            4   GlcNAc     -9     0
            5   Gal       -17     0
EDGE        4
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:3  
            4     5:b1    4:3

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