KEGG   GLYCAN: G00046Help
Entry
G00046                      Glycan                                 

Name
Fuc-Lc4Cer;
III4-a-Fuc-Lc4Cer;
Lea glycolipid
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1
Mass
835.8 (Cer)
Structure
KCF fileKCaMSNFG
Reaction
Pathway
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map01100  Metabolic pathways
Enzyme
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0504 Galb1-3GlcNAcb1-3Galb1-4Glc- (Lacto series)
    G00046  Fuc-alpha1->4(Gal-beta1->3)GlcNAc-beta1->3LacCer
BRITE hierarchy
Reference
1  [PMID:3392043]
  Authors
Larson G, Falk P, Hoskins LC.
  Title
Degradation of human intestinal glycosphingolipids by extracellular glycosidases from mucin-degrading bacteria of the human fecal flora.
  Journal
J Biol Chem 263:10790-8 (1988)
Reference
2  [PMID:9111138]
  Authors
Henry S, Jovall PA, Ghardashkhani S, Elmgren A, Martinsson T, Larson G, Samuelsson B.
  Title
Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of a group O Le(a-b-) nonsecretor.
  Journal
Glycoconj J 14:209-23 (1997)
Reference
3  [PMID:2960671]
  Authors
Holmes EH, Hakomori S, Ostrander GK.
  Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 262:15649-58 (1987)
Other DBs
KCF data Show

NODE        6
            1   Cer        15     0
            2   Glc         8     0
            3   Gal         1     0
            4   GlcNAc     -7     0
            5   LFuc      -15     5
            6   Gal       -15    -5
EDGE        5
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:3  
            4     5:a1    4:4  
            5     6:b1    4:3

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