K00049                      KO                                     

glyoxylate/hydroxypyruvate reductase [EC:]
ko00260  Glycine, serine and threonine metabolism
ko00620  Pyruvate metabolism
ko00630  Glyoxylate and dicarboxylate metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
H00117  Primary hyperoxaluria
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K00049  GRHPR; glyoxylate/hydroxypyruvate reductase
   00630 Glyoxylate and dicarboxylate metabolism
    K00049  GRHPR; glyoxylate/hydroxypyruvate reductase
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    K00049  GRHPR; glyoxylate/hydroxypyruvate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor  glyoxylate reductase (NADP+)
     K00049  GRHPR; glyoxylate/hydroxypyruvate reductase  hydroxypyruvate reductase
     K00049  GRHPR; glyoxylate/hydroxypyruvate reductase
Other DBs
RN: R00465 R01388 R01392 R02527
GO: 0030267 0016618
HSA: 9380(GRHPR)
PTR: 465099(GRHPR)
PPS: 100986688(GRHPR)
GGO: 101130665(GRHPR)
PON: 100171680(GRHPR)
NLE: 100583603(GRHPR)
MCC: 694185(GRHPR)
MCF: 102144581(GRHPR)
CSAB: 103219183(GRHPR)
RRO: 104667514(GRHPR)
RBB: 108516211(GRHPR)
CJC: 100391044(GRHPR)
SBQ: 101048292(GRHPR)
MMU: 76238(Grhpr)
MCAL: 110292456(Grhpr)
MPAH: 110338833(Grhpr)
RNO: 680021(Grhpr)
MUN: 110558830(Grhpr)
CGE: 100752744(Grhpr)
NGI: 103745721(Grhpr)
HGL: 101701531(Grhpr)
CCAN: 109682753(Grhpr)
OCU: 100347792(GRHPR)
TUP: 102477381(GRHPR)
CFA: 612041(GRHPR)
VVP: 112930803(GRHPR)
AML: 100475145(GRHPR)
UMR: 103678479(GRHPR)
UAH: 113260446(GRHPR)
ORO: 101369961(GRHPR)
ELK: 111145704
FCA: 100302391(GRHPR)
PTG: 102967428(GRHPR)
PPAD: 109270134(GRHPR)
AJU: 106981283(GRHPR)
BTA: 504764(GRHPR)
BOM: 102267118(GRHPR)
BIU: 109563042(GRHPR)
BBUB: 102416142(GRHPR)
CHX: 102183324(GRHPR)
OAS: 101108191(GRHPR)
SSC: 100154014(GRHPR)
CFR: 102524449(GRHPR)
CDK: 105102265(GRHPR)
BACU: 103010948(GRHPR)
LVE: 103071384(GRHPR)
OOR: 101280139(GRHPR)
DLE: 111187951(GRHPR)
ECB: 100066566(GRHPR)
EPZ: 103560692(GRHPR)
EAI: 106843901(GRHPR)
MYB: 102254963(GRHPR)
MYD: 102768028(GRHPR)
MNA: 107544991(GRHPR)
HAI: 109386378(GRHPR)
DRO: 112304422(GRHPR)
PALE: 102888080(GRHPR)
RAY: 107511665(GRHPR)
MJV: 108397497(GRHPR)
LAV: 100653729(GRHPR)
TMU: 101344280
MDO: 100018478(GRHPR)
SHR: 100928696(GRHPR)
PCW: 110220544(GRHPR)
OAA: 100078890 107546808(GRHPR)
GGA: 426806(GRHPR)
MGP: 100549242(GRHPR)
CJO: 107306744(GRHPR)
NMEL: 110389952(GRHPR)
APLA: 101789544(GRHPR)
ACYG: 106048866
TGU: 100229871(GRHPR)
LSR: 110482528(GRHPR)
FAB: 101813929(GRHPR)
PHI: 102114621(GRHPR)
PMAJ: 107215710(GRHPR)
CCAE: 111942935
CCW: 104695842(GRHPR)
ETL: 114055219(GRHPR)
CLV: 102096371(GRHPR)
EGZ: 104129511(GRHPR)
NNI: 104012536(GRHPR)
ACUN: 113490425(GRHPR)
PADL: 103914609(GRHPR)
AMJ: 102561417 102562816(GRHPR)
CMY: 102937531 102937755(GRHPR)
CPIC: 101939051(GRHPR) 101940973
ACS: 100558748(grhpr)
PVT: 110077846(GRHPR)
PBI: 103059051(GRHPR)
PMUR: 107291253(GRHPR)
TSR: 106537446(GRHPR)
PMUA: 114587374(GRHPR)
GJA: 107107231(GRHPR)
XLA: 398508(grhpr.2.L) 398631 414606(grhpr.1.L)
XTR: 493279(grhpr.2) 594879 780243(grhpr.1)
DRE: 402985(grhprb) 497183(grhpra)
CCAR: 109086669(grhpr)
IPU: 100528185(grhpr) 108260755
PHYP: 113544290 113547165(grhpr)
AMEX: 103027682 103046658(grhpr)
EEE: 113582659(grhpr) 113586468
TRU: 101071406(grhpr) 101076742
LCO: 104924345 104933258(grhpr)
NCC: 104945892 104947241(grhpr)
ONL: 100699147(grhpr) 100707614
PRET: 103466594 103471304(grhpr)
KMR: 108231960(grhprb) 108242403(grhpra)
CSEM: 103383717(grhpr) 103390973
HCQ: 109518759 109519752(grhpr)
ELS: 105009649(grhpr) 105026161
PKI: 111833437(grhpr) 111844225
CMK: 103182154(grhpr)
RTP: 109917484(grhpr)
BFO: 118412687
CIN: 100178763
APLC: 110984951
SKO: 100375265
DME: Dmel_CG1236(CG1236)
DSE: 6614018
DSI: Dsimw501_GD19816(Dsim_GD19816) Dsimw501_GD24283(Dsim_GD24283) Dsimw501_GD24284(Dsim_GD24284) Dsimw501_GD24286(Dsim_GD24286)
DAN: 6499141
AME: 410042
CSOL: 105366286
CLEC: 106660939
ZNE: 110831039
FCD: 110862584
PVM: 113806196
DPTE: 113789079
EGL: EGR_05219
AMIL: 114955132
PDAM: 113665004
SPIS: 111329423
PTE: PTT_17661
CNE: CNC02760
MGL: MGL_3541
MRT: MRET_0894
 » show all
Booth MP, Conners R, Rumsby G, Brady RL
Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase.
J Mol Biol 360:178-89 (2006)

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