KEGG   ORTHOLOGY: K00064
Entry
K00064                      KO                                     

Name
E1.1.1.122
Definition
D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]
Pathway
ko00051  Fructose and mannose metabolism
ko00053  Ascorbate and aldarate metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K00064  E1.1.1.122; D-threo-aldose 1-dehydrogenase
   00053 Ascorbate and aldarate metabolism
    K00064  E1.1.1.122; D-threo-aldose 1-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.122  D-threo-aldose 1-dehydrogenase
     K00064  E1.1.1.122; D-threo-aldose 1-dehydrogenase
Other DBs
RN: R07675 R08926
COG: COG0667
GO: 0047834
Genes
DSR: 110180731
LCQ: 111688131
ECOO: ECRM13514_5689
ECOH: ECRM13516_5429
EUM: ECUMN_5020
ECLS: LI67_001195
EBG: FAI37_06285
EAE: EAE_12040
EAR: CCG31537
CYO: CD187_10450
SERF: L085_03455
ECA: ECA0250
PATR: EV46_01375
PATO: GZ59_02810
DDQ: DDI_0877
XCI: XCAW_00111(tas) XCAW_00552(tas)
XOM: XOO4276(XOO4276)
XOO: XOO4539(Tas)
XOP: PXO_03262
XAL: XALC_0444
XPH: XppCFBP6546_11135(XppCFBP6546P_11135) XppCFBP6546_13450(XppCFBP6546P_13450)
SML: Smlt1679
VNI: VIBNI_B0418(pld)
PFS: PFLU_2568
PFC: PflA506_2323(pld1)
PFB: VO64_0794
PMAN: OU5_6061
PSA: PST_2004
PSTT: CH92_11250
PSEM: TO66_18440
PANR: A7J50_2453
PSIL: PMA3_10780
ABY: ABAYE1312
ABN: AB57_2577
ABB: ABBFA_01207(pld1)
PART: PARC_b0008
CJA: CJA_1135
LHA: LHA_3083
LLG: 44548918_01690(pld1)
LCJ: NCTC11976_01732(pld1)
LWA: SAMEA4504053_1259(pld1)
GAI: IMCC3135_03275(pld1_1) IMCC3135_04530(fdh) IMCC3135_09520(pld1_2) IMCC3135_12580(pld1_3) IMCC3135_19460(pld1_4)
CSA: Csal_0369
SALN: SALB1_2489
REH: H16_A1691(h16_A1691)
CNC: CNE_2c21340(pld2)
RME: Rmet_5014
BPSE: BDL_4018(pld1)
BPSM: BBQ_5407(pld1)
BPSU: BBN_4189(pld1)
BPSD: BBX_5856(pld1)
BPK: BBK_3703(pld1)
BPSO: X996_3970(pld1)
BUT: X994_3829(pld1)
BCJ: BCAS0159
BCEW: DM40_5652
BMUL: NP80_5200
BCT: GEM_4640
BDL: AK34_5058(pld1)
BLAT: WK25_18475
BTEI: WS51_30150
BSTG: WT74_27295
BGU: KS03_4084(pld1)
BGO: BM43_3348 BM43_4447(pld1)
BXB: DR64_4344(pld1) DR64_5290(pld1)
BFN: OI25_5368(pld1)
PPUL: RO07_16975
CABA: SBC2_54830(pld1)
POL: Bpro_2212
AAA: Acav_1659
VEI: Veis_0846
HYB: Q5W_24350
JAG: GJA_3273
CARE: LT85_3072
CPRA: CPter91_0381(pld1)
MXA: MXAN_0697
MES: Meso_1609
SFD: USDA257_c58770(pld)
AVI: Avi_5131 Avi_6096(fdh)
RLE: RL0520
RLG: Rleg_0159
SHZ: shn_02850
OAN: Oant_0357
OAH: DR92_2583(pld1)
OCH: CES85_0301(pld1)
BJA: blr1124
BRS: S23_66950
XAU: Xaut_1060
AZC: AZC_2780
MAQU: Maq22A_c15790(tas)
MSL: Msil_0205
PLEO: OHA_1_00229(fdh) OHA_1_01099(pld1_1) OHA_1_01758(pld1_2)
MMED: Mame_04204(pld1_1) Mame_04375(pld1_2) Mame_04711(pld1_3)
HDI: HDIA_0473(pld1_1) HDIA_2064(pld1_2) HDIA_3111(pld1_3)
CAK: Caul_1547
RUT: FIU92_02900(pld1)
RSP: RSP_0351
JAN: Jann_2111
PSF: PSE_5072
OAR: OA238_c17010(pld1) OA238_c17920(pld2) OA238_c24200(pld3)
OTM: OSB_06460(pld1)
LABT: FIU93_25405(pld1) FIU93_29135(pld2)
MARU: FIU81_02325(pld1)
MALU: KU6B_44100
HNE: HNE_2134
HBA: Hbal_2682
GAK: X907_2339
NAR: Saro_2433
STAX: MC45_18180
SPHI: TS85_17835
SINB: SIDU_14910
ELI: ELI_09965
GOH: B932_2844
KSC: CD178_00258(pld1)
ASZ: ASN_3382 ASN_866(fdh)
SHUM: STHU_34150
BCE: BC3410
BCZ: BCE33L3116(fdh)
BCQ: BCQ_3213(fdh)
BNC: BCN_3231
BTK: BT9727_3188(fdh)
BTM: MC28_4111
BTG: BTB_c34760(pld)
BTI: BTG_02535
BTW: BF38_4571
BMQ: BMQ_3843
BMD: BMD_3834
BMH: BMWSH_1380(fdh)
BMEG: BG04_758
BEO: BEH_26555
BCL: ABC1415
OIH: OB0307
HLI: HLI_12635
JEO: JMA_10050
MPA: MAP_0955
MAO: MAP4_2905
MAVI: RC58_14420
MAVU: RE97_14445
MIT: OCO_10100
MIA: OCU_10110
MID: MIP_01662
MYO: OEM_10270
MIR: OCQ_10200
MMM: W7S_05030
MSHG: MSG_04026
ROP: ROP_21180
TPR: Tpau_0762
SCO: SCO0349(SCF41.08) SCO7162(SC9A4.24c)
SGB: WQO_33030
SFA: Sfla_0438
SVE: SVEN_0070
SALS: SLNWT_0634
STRP: F750_6560
SFI: SFUL_52
SALU: DC74_2136
SALL: SAZ_11255
SLD: T261_6573
SAMB: SAM23877_7134(fdh)
SPRI: SPRI_0778
SRW: TUE45_00156(fdh) TUE45_06264(pld1)
SLE: sle_17780(sle_17780)
SLAU: SLA_3544
SGE: DWG14_01188(fdh_1) DWG14_07240(fdh_2) DWG14_08164(fdh_3)
MTS: MTES_2573
MOO: BWL13_02385(fdh)
MLV: CVS47_00586(fdh) CVS47_02926(pld1)
MOY: CVS54_03332(fdh_2)
ART: Arth_1922
ARR: ARUE_c39320(pld)
ARM: ART_3287
BCV: Bcav_4072
LMOI: VV02_06950
XCE: Xcel_2224
CFL: Cfla_3459
CFI: Celf_0193
MPH: MLP_07540
NDA: Ndas_1187
SRO: Sros_8210
ACE: Acel_1596
KRA: Krad_4195
SEN: SACE_3934
AMYY: YIM_39845(fdh)
AORI: SD37_29585
AMI: Amir_0396
SESP: BN6_04340(pld1)
KAL: KALB_480
ACTI: UA75_11960
ACAD: UA74_11875
AHG: AHOG_11200(fdh)
ASE: ACPL_4160(hpcE)
ACTN: L083_5672
AFS: AFR_29090
ACTS: ACWT_4031
RXY: Rxyl_3006
RCA: Rcas_4422
TRO: trd_0246
TTR: Tter_0272
RBA: RB5820(fucO)
ABAS: ACPOL_2911
SMIZ: 4412673_01909(fdh)
SDJ: NCTC13534_02670(fdh)
GFL: GRFL_2858
ZPR: ZPR_1994
RAI: RA0C_1703
RAR: RIA_0787
RAG: B739_0451
RAE: G148_0129
RAT: M949_0898
CTAK: 4412677_00569(pld1)
 » show all

KEGG   ORTHOLOGY: K18333
Entry
K18333                      KO                                     

Name
K18333
Definition
L-fucose dehydrogenase
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K18333  K18333; L-fucose dehydrogenase
Other DBs
RN: R08926
COG: COG1028
Genes
CCON: AFK62_18615
EAE: EAE_05260
EAR: CCG32946
PGE: LG71_02970
IZH: FEM41_03690
SMAR: SM39_4975
SMAC: SMDB11_4718
SMW: SMWW4_v1c05980
SPE: Spro_0642
SRR: SerAS9_0578
SRL: SOD_c05100(fabG2)
SPLY: Q5A_002680(linC_1)
SMAF: D781_0588
SERF: L085_01110
SFJ: SAMEA4384070_0669(lvr_1)
SOF: NCTC11214_00914(lvr)
RAA: Q7S_23601
EBI: EbC_34960
SALN: SALB1_1054
BMA: BMAA0644
BMAL: DM55_4782
BMAE: DM78_3207
BMAQ: DM76_3736
BMAI: DM57_12325
BMAF: DM51_4360
BMAZ: BM44_4772
BMAB: BM45_4960
BPS: BPSS0794
BPSE: BDL_4076
BPSM: BBQ_5348
BPSU: BBN_4248
BPSD: BBX_5914
BPK: BBK_3651
BPSH: DR55_4547
BPSA: BBU_5242
BPSO: X996_4023
BUT: X994_3775
BTQ: BTQ_4889
BTJ: BTJ_3514
BTZ: BTL_4362
BTD: BTI_5612
BTV: BTHA_3594
BTHE: BTN_4014
BTHM: BTRA_4079
BTHA: DR62_4049
BTHL: BG87_4345
BOK: DM82_4915
BOC: BG90_5680
BVE: AK36_3378
BCN: Bcen_3327
BCJ: BCAM2283
BCEN: DM39_6870
BCEW: DM40_4983
BCEO: I35_6174
BAM: Bamb_4448
BMJ: BMULJ_04919(fabG)
BMU: Bmul_3598
BMK: DM80_4983
BMUL: NP80_4942
BCT: GEM_3407
BCED: DM42_5708
BDL: AK34_3516
BCON: NL30_01145
BUB: BW23_3447
BLAT: WK25_27395
BTEI: WS51_08435
BSEM: WJ12_31305
BPSL: WS57_14830
BMEC: WJ16_29755
BSTG: WT74_30135
BGU: KS03_2653
BUK: MYA_3001
BUL: BW21_5300
AMIM: MIM_c09600
RFR: Rfer_3136
CFU: CFU_2101(sdr3)
CARE: LT85_1598
CJE: Cj0485
CJI: CJSA_0456
CJS: CJS3_0477
CJEJ: N564_00472
CJEU: N565_00521
CJEN: N755_00520
CJEI: N135_00537
CJER: H730_03005
CJY: QZ67_00496(fabG_2)
CJQ: UC78_0473(xecE)
CJR: CJE0535
CFZ: CSG_9300
CCF: YSQ_07415
CCY: YSS_02240
CCOI: YSU_06425
CCOF: VC76_02555(ped)
CCOO: ATE51_03232(ped)
CIS: CINS_1511
AMIH: CO731_01018(linC)
SSAN: NX02_10175
ACR: Acry_1855
GDI: GDI2664
GDJ: Gdia_0877
CAMG: CAMM_07790
BBRC: B7019_1909
BKS: BBKW_1836
BPSC: BBPC_1773
BSCA: BBSC_0457
GVG: HMPREF0421_20694(fabG)
OBG: Verru16b_01340(fabG_3)
PIR: VN12_09565(tsaC1)
PEH: Spb1_34800(tsaC1_2)
FMR: Fuma_05288(ydaD_2)
GMR: GmarT_50410(tsaC1)
ACA: ACP_3287
CPI: Cpin_1993
FLN: FLA_0504
SMIZ: 4412673_01332(fabG_1)
SDJ: NCTC13534_02085(srlD)
MUC: MuYL_3109
MGOT: MgSA37_02345(lvr)
DFE: Dfer_5643
SLI: Slin_0310
LBY: Lbys_2061
FAE: FAES_4384
GFO: GFO_1703
FJO: Fjoh_4118
FJG: BB050_01492(cpnA_1) BB050_03317(cpnA_3)
ZPR: ZPR_4360
MARF: CJ739_935
EAO: BD94_3584
ELB: VO54_03061(fabG_3)
 » show all
Reference
  Authors
Hobbs ME, Vetting M, Williams HJ, Narindoshvili T, Kebodeaux DM, Hillerich B, Seidel RD, Almo SC, Raushel FM
  Title
Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.
  Journal
Biochemistry 52:239-53 (2013)
DOI:10.1021/bi3015554
  Sequence

KEGG   ENZYME: 1.1.1.122
Entry
EC 1.1.1.122                Enzyme                                 

Name
D-threo-aldose 1-dehydrogenase;
L-fucose dehydrogenase;
(2S,3R)-aldose dehydrogenase;
dehydrogenase, L-fucose;
L-fucose (D-arabinose) dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-threo-aldose:NAD+ 1-oxidoreductase
Reaction(IUBMB)
a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH + H+ [RN:R07148]
Reaction(KEGG)
R07148 > R08926;
(other) R07675
Substrate
D-threo-aldose [CPD:C02143];
NAD+ [CPD:C00003]
Product
D-threo-aldono-1,5-lactone [CPD:C16581];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on L-fucose, D-arabinose and L-xylose; the animal enzyme was also shown to act on L-arabinose, and the enzyme from Pseudomonas caryophylli on L-glucose.
History
EC 1.1.1.122 created 1972
Pathway
ec00051  Fructose and mannose metabolism
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K00064  D-threo-aldose 1-dehydrogenase
Genes
DSR: 110180731
LCQ: 111688131
ECOO: ECRM13514_5689
ECOH: ECRM13516_5429
EUM: ECUMN_5020
ECLS: LI67_001195
EBG: FAI37_06285
EAE: EAE_12040
EAR: CCG31537
CYO: CD187_10450
SERF: L085_03455
ECA: ECA0250
PATR: EV46_01375
PATO: GZ59_02810
DDQ: DDI_0877
XCI: XCAW_00111(tas) XCAW_00552(tas)
XOM: XOO4276(XOO4276)
XOO: XOO4539(Tas)
XOP: PXO_03262
XAL: XALC_0444
XPH: XppCFBP6546_11135(XppCFBP6546P_11135) XppCFBP6546_13450(XppCFBP6546P_13450)
SML: Smlt1679
VNI: VIBNI_B0418(pld)
PFS: PFLU_2568
PFC: PflA506_2323(pld1)
PFB: VO64_0794
PMAN: OU5_6061
PSA: PST_2004
PSTT: CH92_11250
PSEM: TO66_18440
PANR: A7J50_2453
PSIL: PMA3_10780
ABY: ABAYE1312
ABN: AB57_2577
ABB: ABBFA_01207(pld1)
PART: PARC_b0008
CJA: CJA_1135
LHA: LHA_3083
LLG: 44548918_01690(pld1)
LCJ: NCTC11976_01732(pld1)
LWA: SAMEA4504053_1259(pld1)
GAI: IMCC3135_03275(pld1_1) IMCC3135_04530(fdh) IMCC3135_09520(pld1_2) IMCC3135_12580(pld1_3) IMCC3135_19460(pld1_4)
CSA: Csal_0369
SALN: SALB1_2489
REH: H16_A1691(h16_A1691)
CNC: CNE_2c21340(pld2)
RME: Rmet_5014
BPSE: BDL_4018(pld1)
BPSM: BBQ_5407(pld1)
BPSU: BBN_4189(pld1)
BPSD: BBX_5856(pld1)
BPK: BBK_3703(pld1)
BPSO: X996_3970(pld1)
BUT: X994_3829(pld1)
BCJ: BCAS0159
BCEW: DM40_5652
BMUL: NP80_5200
BCT: GEM_4640
BDL: AK34_5058(pld1)
BLAT: WK25_18475
BTEI: WS51_30150
BSTG: WT74_27295
BGU: KS03_4084(pld1)
BGO: BM43_3348 BM43_4447(pld1)
BXB: DR64_4344(pld1) DR64_5290(pld1)
BFN: OI25_5368(pld1)
PPUL: RO07_16975
CABA: SBC2_54830(pld1)
POL: Bpro_2212
AAA: Acav_1659
VEI: Veis_0846
HYB: Q5W_24350
JAG: GJA_3273
CARE: LT85_3072
CPRA: CPter91_0381(pld1)
MXA: MXAN_0697
MES: Meso_1609
SFD: USDA257_c58770(pld)
AVI: Avi_5131 Avi_6096(fdh)
RLE: RL0520
RLG: Rleg_0159
SHZ: shn_02850
OAN: Oant_0357
OAH: DR92_2583(pld1)
OCH: CES85_0301(pld1)
BJA: blr1124
BRS: S23_66950
XAU: Xaut_1060
AZC: AZC_2780
MAQU: Maq22A_c15790(tas)
MSL: Msil_0205
PLEO: OHA_1_00229(fdh) OHA_1_01099(pld1_1) OHA_1_01758(pld1_2)
MMED: Mame_04204(pld1_1) Mame_04375(pld1_2) Mame_04711(pld1_3)
HDI: HDIA_0473(pld1_1) HDIA_2064(pld1_2) HDIA_3111(pld1_3)
CAK: Caul_1547
RUT: FIU92_02900(pld1)
RSP: RSP_0351
JAN: Jann_2111
PSF: PSE_5072
OAR: OA238_c17010(pld1) OA238_c17920(pld2) OA238_c24200(pld3)
OTM: OSB_06460(pld1)
LABT: FIU93_25405(pld1) FIU93_29135(pld2)
MARU: FIU81_02325(pld1)
MALU: KU6B_44100
HNE: HNE_2134
HBA: Hbal_2682
GAK: X907_2339
NAR: Saro_2433
STAX: MC45_18180
SPHI: TS85_17835
SINB: SIDU_14910
ELI: ELI_09965
GOH: B932_2844
KSC: CD178_00258(pld1)
ASZ: ASN_3382 ASN_866(fdh)
SHUM: STHU_34150
BCE: BC3410
BCZ: BCE33L3116(fdh)
BCQ: BCQ_3213(fdh)
BNC: BCN_3231
BTK: BT9727_3188(fdh)
BTM: MC28_4111
BTG: BTB_c34760(pld)
BTI: BTG_02535
BTW: BF38_4571
BMQ: BMQ_3843
BMD: BMD_3834
BMH: BMWSH_1380(fdh)
BMEG: BG04_758
BEO: BEH_26555
BCL: ABC1415
OIH: OB0307
HLI: HLI_12635
JEO: JMA_10050
MPA: MAP_0955
MAO: MAP4_2905
MAVI: RC58_14420
MAVU: RE97_14445
MIT: OCO_10100
MIA: OCU_10110
MID: MIP_01662
MYO: OEM_10270
MIR: OCQ_10200
MMM: W7S_05030
MSHG: MSG_04026
ROP: ROP_21180
TPR: Tpau_0762
SCO: SCO0349(SCF41.08) SCO7162(SC9A4.24c)
SGB: WQO_33030
SFA: Sfla_0438
SVE: SVEN_0070
SALS: SLNWT_0634
STRP: F750_6560
SFI: SFUL_52
SALU: DC74_2136
SALL: SAZ_11255
SLD: T261_6573
SAMB: SAM23877_7134(fdh)
SPRI: SPRI_0778
SRW: TUE45_00156(fdh) TUE45_06264(pld1)
SLE: sle_17780(sle_17780)
SLAU: SLA_3544
SGE: DWG14_01188(fdh_1) DWG14_07240(fdh_2) DWG14_08164(fdh_3)
MTS: MTES_2573
MOO: BWL13_02385(fdh)
MLV: CVS47_00586(fdh) CVS47_02926(pld1)
MOY: CVS54_03332(fdh_2)
ART: Arth_1922
ARR: ARUE_c39320(pld)
ARM: ART_3287
BCV: Bcav_4072
LMOI: VV02_06950
XCE: Xcel_2224
CFL: Cfla_3459
CFI: Celf_0193
MPH: MLP_07540
NDA: Ndas_1187
SRO: Sros_8210
ACE: Acel_1596
KRA: Krad_4195
SEN: SACE_3934
AMYY: YIM_39845(fdh)
AORI: SD37_29585
AMI: Amir_0396
SESP: BN6_04340(pld1)
KAL: KALB_480
ACTI: UA75_11960
ACAD: UA74_11875
AHG: AHOG_11200(fdh)
ASE: ACPL_4160(hpcE)
ACTN: L083_5672
AFS: AFR_29090
ACTS: ACWT_4031
RXY: Rxyl_3006
RCA: Rcas_4422
TRO: trd_0246
TTR: Tter_0272
RBA: RB5820(fucO)
ABAS: ACPOL_2911
SMIZ: 4412673_01909(fdh)
SDJ: NCTC13534_02670(fdh)
GFL: GRFL_2858
ZPR: ZPR_1994
RAI: RA0C_1703
RAR: RIA_0787
RAG: B739_0451
RAE: G148_0129
RAT: M949_0898
CTAK: 4412677_00569(pld1)
 » show all
Reference
1  [PMID:40609]
  Authors
Sasajima KI, Sinskey AJ.
  Title
Oxidation of L-glucose by a Pseudomonad.
  Journal
Biochim Biophys Acta 571:120-6 (1979)
DOI:10.1016/0005-2744(79)90232-8
Reference
2  [PMID:4309152]
  Authors
Schachter H, Sarney J, McGuire EJ, Roseman S.
  Title
Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver.
  Journal
J Biol Chem 244:4785-92 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.122
IUBMB Enzyme Nomenclature: 1.1.1.122
ExPASy - ENZYME nomenclature database: 1.1.1.122
BRENDA, the Enzyme Database: 1.1.1.122
CAS: 9082-70-6

KEGG   REACTION: R08926
Entry
R08926                      Reaction                               

Name
L-fucose:NAD+ 1-oxidoreductase
Definition
6-Deoxy-L-galactose + NAD+ <=> L-Fucono-1,5-lactone + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00066  C01019_C18028
Enzyme
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K00064  D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]
K18333  L-fucose dehydrogenase

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