KEGG   ORTHOLOGY: K00093
Entry
K00093                      KO                                     
Symbol
mdh
Name
methanol dehydrogenase [EC:1.1.1.244]
Pathway
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R00605  methanol:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00093  mdh; methanol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.244  methanol dehydrogenase
     K00093  mdh; methanol dehydrogenase
Other DBs
GO: 0050093
Genes
APES: FOC84_29750
MESS: ABSY17_07035
BMET: BMMGA3_17200(mdh)
AG: AAA22593(mdh)
Reference
PMID:2673121
  Authors
Arfman N, Watling EM, Clement W, van Oosterwijk RJ, de Vries GE, Harder W, Attwood MM, Dijkhuizen L
  Title
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.
  Journal
Arch Microbiol 152:280-8 (1989)
DOI:10.1007/BF00409664
Reference
PMID:1644761
  Authors
de Vries GE, Arfman N, Terpstra P, Dijkhuizen L
  Title
Cloning, expression, and sequence analysis of the Bacillus methanolicus C1 methanol dehydrogenase gene.
  Journal
J Bacteriol 174:5346-53 (1992)
DOI:10.1128/JB.174.16.5346-5353.1992
  Sequence
[ag:AAA22593]

  All links  
Ontology (1)   
   GO (1)   
Gene (1)   
   OC (1)   
All databases (2)   

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KEGG   ENZYME: 1.1.1.244
Entry
EC 1.1.1.244                Enzyme                                 
Name
methanol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
methanol:NAD+ oxidoreductase
Reaction(IUBMB)
methanol + NAD+ = formaldehyde + NADH + H+ [RN:R00605]
Reaction(KEGG)
R00605
Substrate
methanol [CPD:C00132];
NAD+ [CPD:C00003]
Product
formaldehyde [CPD:C00067];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.244 created 1992
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00093  methanol dehydrogenase
Genes
APES: FOC84_29750
MESS: ABSY17_07035
BMET: BMMGA3_17200(mdh)
Reference
1  [PMID:2673121]
  Authors
Arfman N, Watling EM, Clement W, van Oosterwijk RJ, de Vries GE, Harder W, Attwood MM, Dijkhuizen L
  Title
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.
  Journal
Arch Microbiol 152:280-8 (1989)
DOI:10.1007/BF00409664
  Sequence
[ag:AAA22593]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.244
IUBMB Enzyme Nomenclature: 1.1.1.244
ExPASy - ENZYME nomenclature database: 1.1.1.244
BRENDA, the Enzyme Database: 1.1.1.244
CAS: 74506-37-9

  All links  
Protein sequence (1357)   
   UniProt (453)   
   SWISS-PROT (1)   
   RefSeq(pep) (882)   
   PDBSTR (20)   
   PMD (1)   
DNA sequence (16821)   
   RefSeq(nuc) (15882)   
   GenBank (513)   
   EMBL (426)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   InterPro (4)   
   PROSITE(DOC) (1)   
All databases (18185)   

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KEGG   REACTION: R00605
Entry
R00605                      Reaction                               
Name
methanol:NAD+ oxidoreductase
Definition
Methanol + NAD+ <=> Formaldehyde + NADH + H+
Equation
C00132 + C00003 <=> C00067 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00034  C00067_C00132
Enzyme
1.1.1.244
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.244
     R00605  Methanol + NAD+ <=> Formaldehyde + NADH + H+
Orthology
K00093  methanol dehydrogenase [EC:1.1.1.244]
Other DBs
RHEA: 19404

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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