KEGG   ORTHOLOGY: K00093
Entry
K00093                      KO                                     

Name
mdh
Definition
methanol dehydrogenase [EC:1.1.1.244]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00093  mdh; methanol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.244  methanol dehydrogenase
     K00093  mdh; methanol dehydrogenase
Other DBs
RN: R00605
GO: 0050093
Genes
BMET: BMMGA3_17200(mdh)
AG: AAA22593(mdh)
Reference
PMID:2673121
  Authors
Arfman N, Watling EM, Clement W, van Oosterwijk RJ, de Vries GE, Harder W, Attwood MM, Dijkhuizen L
  Title
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.
  Journal
Arch Microbiol 152:280-8 (1989)
DOI:10.1007/BF00409664
Reference
PMID:1644761
  Authors
de Vries GE, Arfman N, Terpstra P, Dijkhuizen L
  Title
Cloning, expression, and sequence analysis of the Bacillus methanolicus C1 methanol dehydrogenase gene.
  Journal
J Bacteriol 174:5346-53 (1992)
DOI:10.1128/JB.174.16.5346-5353.1992
  Sequence

KEGG   ENZYME: 1.1.1.244
Entry
EC 1.1.1.244                Enzyme                                 

Name
methanol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
methanol:NAD+ oxidoreductase
Reaction(IUBMB)
methanol + NAD+ = formaldehyde + NADH + H+ [RN:R00605]
Reaction(KEGG)
R00605
Substrate
methanol [CPD:C00132];
NAD+ [CPD:C00003]
Product
formaldehyde [CPD:C00067];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.244 created 1992
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00093  methanol dehydrogenase
Genes
BMET: BMMGA3_17200(mdh)
Reference
1  [PMID:2673121]
  Authors
Arfman N, Watling EM, Clement W, van Oosterwijk RJ, de Vries GE, Harder W, Attwood MM, Dijkhuizen L
  Title
Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme.
  Journal
Arch Microbiol 152:280-8 (1989)
DOI:10.1007/BF00409664
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.244
IUBMB Enzyme Nomenclature: 1.1.1.244
ExPASy - ENZYME nomenclature database: 1.1.1.244
BRENDA, the Enzyme Database: 1.1.1.244
CAS: 74506-37-9

KEGG   REACTION: R00605
Entry
R00605                      Reaction                               

Name
methanol:NAD+ oxidoreductase
Definition
Methanol + NAD+ <=> Formaldehyde + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00034  C00067_C00132
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K00093  methanol dehydrogenase [EC:1.1.1.244]
Other DBs
RHEA: 19404

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