KEGG   ORTHOLOGY: K00141Help
Entry
K00141                      KO                                     

Name
xylC
Definition
benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]
Pathway
ko00622  Xylene degradation
ko00623  Toluene degradation
ko00627  Aminobenzoate degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Module
M00537  Xylene degradation, xylene => methylbenzoate
M00538  Toluene degradation, toluene => benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K00141  xylC; benzaldehyde dehydrogenase (NAD)
   00623 Toluene degradation
    K00141  xylC; benzaldehyde dehydrogenase (NAD)
   00622 Xylene degradation
    K00141  xylC; benzaldehyde dehydrogenase (NAD)
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00538  Toluene degradation, toluene => benzoate
     K00141  xylC; benzaldehyde dehydrogenase (NAD)
    M00537  Xylene degradation, xylene => methylbenzoate
     K00141  xylC; benzaldehyde dehydrogenase (NAD)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.28  benzaldehyde dehydrogenase (NAD+)
     K00141  xylC; benzaldehyde dehydrogenase (NAD)
BRITE hierarchy
Other DBs
RN: R01293 R01419 R05289 R05663 R05664 R07667
COG: COG1012
GO: 0018479
Genes
KOE: A225_2826
KOY: J415_17845
KOM: HR38_18115
KOK: KONIH1_13855
KOC: AB185_21965
EAE: EAE_20110
EAR: CCG29859
XCC: XCC0354(xylC)
XCB: XC_0366
XCA: xcc-b100_0380
XCP: XCR_4161
XCV: XCV0367
XAX: XACM_0342
XAC: XAC0354(xylC)
XCI: XCAW_00760(xylC)
XOR: XOC_4559
XAL: XALC_3040
SMT: Smal_3490
PSD: DSC_14830
PPI: YSA_10876
PPX: T1E_5479(xylC) T1E_5480
PST: PSPTO_2950(xylcC)
PSB: Psyr_2734
PSYR: N018_13560
PSP: PSPPH_2427(xylC)
PFS: PFLU_3306
PSES: PSCI_4651(xylC)
ACI: ACIAD1430(areC)
SALN: SALB1_1081
RSO: RSp0229
RSL: RPSI07_mp0182(xylC)
RSN: RSPO_m00219(xylC)
RSM: CMR15_mp10201(xylC)
RSE: F504_3669
REH: H16_A1114(h16_A1114) H16_A1772(h16_A1772)
CNC: CNE_1c10580(doxF)
BMA: BMA0347
BMAL: DM55_1742
BMAE: DM78_251
BMAQ: DM76_1718
BMAI: DM57_2374
BMAF: DM51_142
BMAZ: BM44_2881
BMAB: BM45_665
BPS: BPSL0843
BPM: BURPS1710b_1049(vdh)
BPSE: BDL_1184
BPSM: BBQ_2605
BPSU: BBN_2728
BPSD: BBX_3131
BPK: BBK_663
BPSH: DR55_277
BPSA: BBU_1337
BPSO: X996_3359
BUT: X994_1893
BTE: BTH_I0706
BTQ: BTQ_724
BTJ: BTJ_1716
BTZ: BTL_2995
BTD: BTI_2978
BTV: BTHA_3215
BTHE: BTN_1714
BTHM: BTRA_3310
BTHA: DR62_1904
BTHL: BG87_3190
BOK: DM82_232
BOC: BG90_792
BCJ: BCAL2795
BCEN: DM39_2666 DM39_5087(xylC)
BCEW: DM40_216
BMU: Bmul_0715
BMJ: BMULJ_02545(xylC)
BMK: DM80_2383
BMUL: NP80_2723
BCT: GEM_0848
BCED: DM42_2487 DM42_7068(xylC)
BLAT: WK25_12530
BTEI: WS51_23350
BMEC: WJ16_13250
BGU: KS03_5261
BUL: BW21_3120
BXE: Bxe_C0302
BXB: DR64_8131(xylC)
BPH: Bphy_6158
BFN: OI25_5083
PPNO: DA70_15165
PPNM: LV28_15515
PPUL: RO07_09560
PSPU: NA29_05475
PAPI: SG18_10060
BPT: Bpet1388
AJS: Ajs_2827
AAA: Acav_1926
ACRA: BSY15_3509
HYB: Q5W_24285
CBAA: SRAA_2263
CBAB: SMCB_2280
EBA: ebA5642(ald)
AZO: azo2473(xylC)
AOA: dqs_2617
AMIH: CO731_00658(xylC)
AGC: BSY240_7
RIR: BN877_p0367(nahF)
BJA: blr6417(vdh)
BBT: BBta_6645(xylC)
CCR: CC_2397
CSE: Cseg_1739
SPHR: BSY17_3075
RER: RER_55880(xylC)
REY: O5Y_26650
SCO: SCO7436(SC6D11.32c)
SVE: SVEN_0497
SDV: BN159_1191(xylC)
SALU: DC74_6069
SALL: SAZ_31310
SLV: SLIV_02130(xylC)
STRE: GZL_02781
STRM: M444_29625
SAMB: SAM23877_0769(xylC)
SPRI: SPRI_3478
SRW: TUE45_01158(xylC_1)
SLE: sle_66310(sle_66310)
STRD: NI25_35465
SLX: SLAV_06040(xylC)
BLIN: BLSMQ_0791
GOB: Gobs_2192
MMAR: MODMU_4266
SEN: SACE_3144(mdlD)
AMD: AMED_6566(xylC)
AMN: RAM_33675
AMM: AMES_6469(xylC)
AMZ: B737_6469(xylC)
AOI: AORI_0924(xylC)
AJA: AJAP_34945(xylC)
AMQ: AMETH_4192(xylC)
PSEE: FRP1_10305
AMI: Amir_2506
ASE: ACPL_5481(xylC)
ACTS: ACWT_5350
CAI: Caci_4885
AG: AAA66218(xylC)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7868591
  Authors
Inoue J, Shaw JP, Rekik M, Harayama S
  Title
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas putida.
  Journal
J Bacteriol 177:1196-201 (1995)
DOI:10.1128/JB.177.5.1196-1201.1995
  Sequence

KEGG   ENZYME: 1.2.1.28Help
Entry
EC 1.2.1.28                 Enzyme                                 

Name
benzaldehyde dehydrogenase (NAD+);
benzaldehyde (NAD+) dehydrogenase;
benzaldehyde dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
benzaldehyde:NAD+ oxidoreductase
Reaction(IUBMB)
benzaldehyde + NAD+ + H2O = benzoate + NADH + 2 H+ [RN:R01419]
Reaction(KEGG)
Substrate
benzaldehyde [CPD:C00261];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
benzoate [CPD:C00180];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.2.1.28 created 1972
Pathway
ec00622  Xylene degradation
ec00623  Toluene degradation
ec00627  Aminobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00141  benzaldehyde dehydrogenase (NAD)
K22417  benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
Genes
ATH: AT1G04580(AO4)
ALY: ARALYDRAFT_470440
CRB: 17900582
CSAT: 104738981
EUS: EUTSA_v10006570mg
BRP: 103844240
BNA: 106402186
BOE: 106295510
KOE: A225_2826
KOY: J415_17845
EAE: EAE_20110
EAR: CCG29859
XCC: XCC0354(xylC)
XCB: XC_0366
XCP: XCR_4161
XCV: XCV0367
XAX: XACM_0342
XAC: XAC0354(xylC)
XCI: XCAW_00760(xylC)
XOR: XOC_4559
XAL: XALC_3040
SMT: Smal_3490
PSD: DSC_14830
PPI: YSA_10876
PPX: T1E_5479(xylC) T1E_5480
PST: PSPTO_2950(xylcC)
PSB: Psyr_2734
PSYR: N018_13560
PSP: PSPPH_2427(xylC)
PFS: PFLU_3306
PSES: PSCI_4651(xylC)
ACI: ACIAD1430(areC)
SALN: SALB1_1081
RSO: RSp0229
RSL: RPSI07_mp0182(xylC)
RSN: RSPO_m00219(xylC)
RSM: CMR15_mp10201(xylC)
RSE: F504_3669
REH: H16_A1114(h16_A1114) H16_A1772(h16_A1772)
CNC: CNE_1c10580(doxF)
BMA: BMA0347
BMAL: DM55_1742
BMAE: DM78_251
BMAQ: DM76_1718
BMAI: DM57_2374
BMAF: DM51_142
BMAZ: BM44_2881
BMAB: BM45_665
BPS: BPSL0843
BPM: BURPS1710b_1049(vdh)
BPSE: BDL_1184
BPSM: BBQ_2605
BPSU: BBN_2728
BPSD: BBX_3131
BPK: BBK_663
BPSH: DR55_277
BPSA: BBU_1337
BPSO: X996_3359
BUT: X994_1893
BTE: BTH_I0706
BTQ: BTQ_724
BTJ: BTJ_1716
BTZ: BTL_2995
BTD: BTI_2978
BTV: BTHA_3215
BTHE: BTN_1714
BTHM: BTRA_3310
BTHA: DR62_1904
BTHL: BG87_3190
BOK: DM82_232
BOC: BG90_792
BCJ: BCAL2795
BCEN: DM39_2666 DM39_5087(xylC)
BCEW: DM40_216
BMU: Bmul_0715
BMJ: BMULJ_02545(xylC)
BMK: DM80_2383
BMUL: NP80_2723
BCT: GEM_0848
BCED: DM42_2487 DM42_7068(xylC)
BLAT: WK25_12530
BTEI: WS51_23350
BMEC: WJ16_13250
BGU: KS03_5261
BUL: BW21_3120
BXE: Bxe_C0302
BXB: DR64_8131(xylC)
BPH: Bphy_6158
BFN: OI25_5083
PPNO: DA70_15165
PPNM: LV28_15515
PPUL: RO07_09560
PSPU: NA29_05475
PAPI: SG18_10060
BPT: Bpet1388
AJS: Ajs_2827
AAA: Acav_1926
ACRA: BSY15_3509
HYB: Q5W_24285
CBAA: SRAA_2263
CBAB: SMCB_2280
EBA: ebA5642(ald)
AZO: azo2473(xylC)
AOA: dqs_2617
AMIH: CO731_00658(xylC)
AGC: BSY240_7
RIR: BN877_p0367(nahF)
BJA: blr6417(vdh)
BBT: BBta_6645(xylC)
CCR: CC_2397
CSE: Cseg_1739
SPHR: BSY17_3075
RER: RER_55880(xylC)
REY: O5Y_26650
SCO: SCO7436(SC6D11.32c)
SVE: SVEN_0497
SDV: BN159_1191(xylC)
SALU: DC74_6069
SALL: SAZ_31310
SLV: SLIV_02130(xylC)
STRE: GZL_02781
STRM: M444_29625
SAMB: SAM23877_0769(xylC)
SPRI: SPRI_3478
SRW: TUE45_01158(xylC_1)
SLE: sle_66310(sle_66310)
STRD: NI25_35465
SLX: SLAV_06040(xylC)
BLIN: BLSMQ_0791
GOB: Gobs_2192
MMAR: MODMU_4266
SEN: SACE_3144(mdlD)
AMD: AMED_6566(xylC)
AMN: RAM_33675
AMM: AMES_6469(xylC)
AMZ: B737_6469(xylC)
AOI: AORI_0924(xylC)
AJA: AJAP_34945(xylC)
AMQ: AMETH_4192(xylC)
PSEE: FRP1_10305
AMI: Amir_2506
ASE: ACPL_5481(xylC)
ACTS: ACWT_5350
CAI: Caci_4885
 » show all
Taxonomy
Reference
1  [PMID:13108854]
  Authors
GUNSALUS CF, STANIER RY, GUNSALUS IC.
  Title
The enzymatic conversion of mandelic acid to benzoic acid. III. Fractionation and properties of the soluble enzymes.
  Journal
J Bacteriol 66:548-53 (1953)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.28
IUBMB Enzyme Nomenclature: 1.2.1.28
ExPASy - ENZYME nomenclature database: 1.2.1.28
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.28
BRENDA, the Enzyme Database: 1.2.1.28
CAS: 37250-93-4

KEGG   REACTION: R07667Help
Entry
R07667                      Reaction                               

Name
3-hydroxybenzaldehyde:NAD+ oxidoreductase
Definition
3-Hydroxybenzaldehyde + NAD+ + H2O <=> 3-Hydroxybenzoate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00075  C00587_C03067
Enzyme
1.2.1.28        1.2.1.64
Pathway
rn00623  Toluene degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K00141  benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]

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