KEGG   ORTHOLOGY: K00217
Entry
K00217                      KO                                     

Name
E1.3.1.32
Definition
maleylacetate reductase [EC:1.3.1.32]
Pathway
ko00361  Chlorocyclohexane and chlorobenzene degradation
ko00362  Benzoate degradation
ko00364  Fluorobenzoate degradation
ko00623  Toluene degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00364 Fluorobenzoate degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00361 Chlorocyclohexane and chlorobenzene degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00623 Toluene degradation
    K00217  E1.3.1.32; maleylacetate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.32  maleylacetate reductase
     K00217  E1.3.1.32; maleylacetate reductase
Other DBs
RN: R02988 R02989 R05355 R06848 R07781 R09137 R09138 R09223 R09224
GO: 0018506
Genes
OTW: 112243693
EBT: EBL_c11390
EAME: GXP68_22270
PLU: plu0145
PLUM: A4R40_00720
PAP: PSPA7_3908
PRE: PCA10_31800(macA)
PCQ: PcP3B5_26700(tfdF_1) PcP3B5_37670(tfdF_2)
PPUN: PP4_21460(macA)
PPUD: DW66_3577 DW66_3594
PFE: PSF113_2029(pnpD2) PSF113_3443(pnpF)
PPUU: PputUW4_02735(tftE)
PKC: PKB_3277(clce1) PKB_3293(tftE) PKB_3626(clce3)
GPS: C427_5376
HBE: BEI_0305
REH: H16_A1786(h16_A1786) H16_B0970(pcpE)
RME: Rmet_5063(macA)
CGD: CR3_2774
BUT: X994_6298
BCJ: BCAL1340(tftE) BCAM0470(macA)
BCEW: DM40_4057
BMJ: BMULJ_05457(linF) BMULJ_05466(linF)
BMK: DM80_6512(tfdF) DM80_6522(tfdF)
BCED: DM42_369(tfdF) DM42_4687
BCON: NL30_23585
BUB: BW23_4753
BLAT: WK25_22600
BTEI: WS51_01150
BPSL: WS57_19040
BMEC: WJ16_21305
BGO: BM43_4097(macA) BM43_5583(macA)
BXE: Bxe_A1126(clcE)
BXB: DR64_3286(tfdF)
BPH: Bphy_5623
BFN: OI25_125
PPNO: DA70_09455
PPNM: LV28_21355
CABA: SBC2_60140(tfdF_1) SBC2_78330(tfdF_2)
BPAR: BN117_2567
BBR: BB2791
BHO: D560_0365(tfdF)
BHM: D558_0361(tfdF)
BHZ: ACR54_02377(fucO)
AXY: AXYL_04103(tftE1) AXYL_06557(tftE2)
AXX: ERS451415_00932(mdh_1)
PUT: PT7_2250
POL: Bpro_2063
PNA: Pnap_3908
AAA: Acav_4142
VEI: Veis_4611
HYR: BSY239_460(tfdF)
HYB: Q5W_08530
HSE: Hsero_3721(macA)
HRB: Hrubri_3689(macA)
LCH: Lcho_0837
RBS: RHODOSMS8_02733(tfdF)
SMI: BN406_06708(tftE)
SIX: BSY16_5880(macA)
SAME: SAMCFNEI73_pC1524(tftE)
ARA: Arad_7158
AVI: Avi_7440(macA)
AGR: AGROH133_08583(macA)
AGC: BSY240_3589(macA)
RLE: pRL120100(tftE2) pRL120215(tftE1)
RLG: Rleg_5540
SHZ: shn_17055
BJA: bll0995 bll2682(macA)
BRA: BRADO2265
BBT: BBta_5141
BRS: S23_46790(macA) S23_68120
AOL: S58_16210
RPB: RPB_4699
RPD: RPD_4409
RPE: RPE_4908
RPT: Rpal_5309
AZC: AZC_1411
MET: M446_1960
PLEO: OHA_1_04037(tfdF)
MMED: Mame_00354(tfdF)
CAK: Caul_0444
PGD: Gal_04190
CID: P73_0379
AHT: ANTHELSMS3_01792(tfdF)
NAR: Saro_2455
SGI: SGRAN_3164(macr)
STAX: MC45_16655
SJP: SJA_C2-04820(linF)
SINB: SIDU_11255
SAMI: SAMIE_4000330(hqdD)
SMIC: SmB9_21830
AAY: WYH_01880(tfdF)
PGV: SL003B_1104(tftE)
MVA: Mvan_4405
CGL: NCgl1112(Cgl1159)
CGB: cg1310(tfdF) cg3386(tcbF)
CGU: WA5_1112(TfdF) WA5_2952(TcbF)
CGM: cgp_1310(tfdF) cgp_3386(tcbF)
CGJ: AR0_14805
CEF: CE2892
CGY: CGLY_10705(tfdF)
CDX: CDES_03620(tftE)
CAMG: CAMM_03445
NFA: NFA_43640
NFR: ERS450000_05551(tfdF)
NAD: NCTC11293_03316(tfdF)
RER: RER_08770(macA)
ROP: ROP_42960(macA)
REQ: REQ_45250
RFA: A3L23_03380(tfdF)
RRT: 4535765_01090(tfdF)
RCR: NCTC10994_01650(tfdF)
SHY: SHJG_8538
SDV: BN159_1527(tfdF)
SPRI: SPRI_6546
SLE: sle_04020(sle_04020)
SGE: DWG14_00024(tfdF_1) DWG14_00033(tfdF_2) DWG14_00197(tfdF_3) DWG14_01102(tfdF_4)
ART: Arth_1936
SERJ: SGUI_0655
NML: Namu_4672
AMYY: YIM_23070(tfdF)
PSEE: FRP1_17125
PSEH: XF36_06620
SESP: BN6_46840
KAL: KALB_5077
ACTI: UA75_15105
ACAD: UA74_14515
AHG: AHOG_13655(tfdF)
ACTN: L083_5618
AFS: AFR_25340
RXY: Rxyl_1051
CWO: Cwoe_1982
EYY: EGYY_06660(EutG)
DFC: DFI_13885
CDIV: CPM_0796
SSO: SSO2490(clcE)
SAI: Saci_1087
SID: M164_0300
SII: LD85_0288
SIH: SiH_0289
SIR: SiRe_0287
SIC: SiL_0273
MSE: Msed_1062
 » show all
Reference
PMID:9171435
  Authors
Kasberg T, Seibert V, Schlomann M, Reineke W
  Title
Cloning, characterization, and sequence analysis of the clcE gene encoding the maleylacetate reductase of Pseudomonas sp. strain B13.
  Journal
J Bacteriol 179:3801-3 (1997)
DOI:10.1128/jb.179.11.3801-3803.1997
  Sequence

KEGG   ENZYME: 1.3.1.32
Entry
EC 1.3.1.32                 Enzyme                                 

Name
maleylacetate reductase;
maleolylacetate reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
3-oxoadipate:NAD(P)+ oxidoreductase
Reaction(IUBMB)
3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+ [RN:R02988 R02989]
Reaction(KEGG)
Substrate
3-oxoadipate [CPD:C00846];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
2-maleylacetate [CPD:C02222];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.3.1.32 created 1983
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00362  Benzoate degradation
ec00364  Fluorobenzoate degradation
ec00623  Toluene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00217  maleylacetate reductase
Genes
OTW: 112243693
EBT: EBL_c11390
EAME: GXP68_22270
PLU: plu0145
PLUM: A4R40_00720
PAP: PSPA7_3908
PRE: PCA10_31800(macA)
PCQ: PcP3B5_26700(tfdF_1) PcP3B5_37670(tfdF_2)
PPUN: PP4_21460(macA)
PPUD: DW66_3577 DW66_3594
PFE: PSF113_2029(pnpD2) PSF113_3443(pnpF)
PPUU: PputUW4_02735(tftE)
PKC: PKB_3277(clce1) PKB_3293(tftE) PKB_3626(clce3)
GPS: C427_5376
HBE: BEI_0305
REH: H16_A1786(h16_A1786) H16_B0970(pcpE)
RME: Rmet_5063(macA)
CGD: CR3_2774
BUT: X994_6298
BCJ: BCAL1340(tftE) BCAM0470(macA)
BCEW: DM40_4057
BMJ: BMULJ_05457(linF) BMULJ_05466(linF)
BMK: DM80_6512(tfdF) DM80_6522(tfdF)
BCED: DM42_369(tfdF) DM42_4687
BCON: NL30_23585
BUB: BW23_4753
BLAT: WK25_22600
BTEI: WS51_01150
BPSL: WS57_19040
BMEC: WJ16_21305
BGO: BM43_4097(macA) BM43_5583(macA)
BXE: Bxe_A1126(clcE)
BXB: DR64_3286(tfdF)
BPH: Bphy_5623
BFN: OI25_125
PPNO: DA70_09455
PPNM: LV28_21355
CABA: SBC2_60140(tfdF_1) SBC2_78330(tfdF_2)
BPAR: BN117_2567
BBR: BB2791
BHO: D560_0365(tfdF)
BHM: D558_0361(tfdF)
BHZ: ACR54_02377(fucO)
AXY: AXYL_04103(tftE1) AXYL_06557(tftE2)
AXX: ERS451415_00932(mdh_1)
PUT: PT7_2250
POL: Bpro_2063
PNA: Pnap_3908
AAA: Acav_4142
VEI: Veis_4611
HYR: BSY239_460(tfdF)
HYB: Q5W_08530
HSE: Hsero_3721(macA)
HRB: Hrubri_3689(macA)
LCH: Lcho_0837
RBS: RHODOSMS8_02733(tfdF)
SMI: BN406_06708(tftE)
SIX: BSY16_5880(macA)
SAME: SAMCFNEI73_pC1524(tftE)
ARA: Arad_7158
AVI: Avi_7440(macA)
AGR: AGROH133_08583(macA)
AGC: BSY240_3589(macA)
RLE: pRL120100(tftE2) pRL120215(tftE1)
RLG: Rleg_5540
SHZ: shn_17055
BJA: bll0995 bll2682(macA)
BRA: BRADO2265
BBT: BBta_5141
BRS: S23_46790(macA) S23_68120
AOL: S58_16210
RPB: RPB_4699
RPD: RPD_4409
RPE: RPE_4908
RPT: Rpal_5309
AZC: AZC_1411
MET: M446_1960
PLEO: OHA_1_04037(tfdF)
MMED: Mame_00354(tfdF)
CAK: Caul_0444
PGD: Gal_04190
CID: P73_0379
AHT: ANTHELSMS3_01792(tfdF)
NAR: Saro_2455
SGI: SGRAN_3164(macr)
STAX: MC45_16655
SJP: SJA_C2-04820(linF)
SINB: SIDU_11255
SAMI: SAMIE_4000330(hqdD)
SMIC: SmB9_21830
AAY: WYH_01880(tfdF)
PGV: SL003B_1104(tftE)
MVA: Mvan_4405
CGL: NCgl1112(Cgl1159)
CGB: cg1310(tfdF) cg3386(tcbF)
CGU: WA5_1112(TfdF) WA5_2952(TcbF)
CGM: cgp_1310(tfdF) cgp_3386(tcbF)
CGJ: AR0_14805
CEF: CE2892
CGY: CGLY_10705(tfdF)
CDX: CDES_03620(tftE)
CAMG: CAMM_03445
NFA: NFA_43640
NFR: ERS450000_05551(tfdF)
NAD: NCTC11293_03316(tfdF)
RER: RER_08770(macA)
ROP: ROP_42960(macA)
REQ: REQ_45250
RFA: A3L23_03380(tfdF)
RRT: 4535765_01090(tfdF)
RCR: NCTC10994_01650(tfdF)
SHY: SHJG_8538
SDV: BN159_1527(tfdF)
SPRI: SPRI_6546
SLE: sle_04020(sle_04020)
SGE: DWG14_00024(tfdF_1) DWG14_00033(tfdF_2) DWG14_00197(tfdF_3) DWG14_01102(tfdF_4)
ART: Arth_1936
SERJ: SGUI_0655
NML: Namu_4672
AMYY: YIM_23070(tfdF)
PSEE: FRP1_17125
PSEH: XF36_06620
SESP: BN6_46840
KAL: KALB_5077
ACTI: UA75_15105
ACAD: UA74_14515
AHG: AHOG_13655(tfdF)
ACTN: L083_5618
AFS: AFR_25340
RXY: Rxyl_1051
CWO: Cwoe_1982
EYY: EGYY_06660(EutG)
DFC: DFI_13885
CDIV: CPM_0796
SSO: SSO2490(clcE)
SAI: Saci_1087
SID: M164_0300
SII: LD85_0288
SIH: SiH_0289
SIR: SiRe_0287
SIC: SiL_0273
MSE: Msed_1062
 » show all
Reference
1  [PMID:7387635]
  Authors
Gaal AB, Neujahr HY.
  Title
Maleylacetate reductase from Trichosporon cutaneum.
  Journal
Biochem J 185:783-6 (1980)
DOI:10.1042/bj1850783
Reference
2  [PMID:7305599]
  Authors
Gaal A, Neujahr HY
  Title
Induction of phenol-metabolizing enzymes in Trichosporon cutaneum.
  Journal
Arch Microbiol 130:54-8 (1981)
DOI:10.1007/bf00527072
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.32
IUBMB Enzyme Nomenclature: 1.3.1.32
ExPASy - ENZYME nomenclature database: 1.3.1.32
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.32
BRENDA, the Enzyme Database: 1.3.1.32
CAS: 69669-65-4

KEGG   REACTION: R02988
Entry
R02988                      Reaction                               

Name
3-oxoadipate:NAD+ oxidoreductase
Definition
3-Oxoadipate + NAD+ <=> 2-Maleylacetate + NADH + H+
Equation
Comment
NADP+ (see R02989)
Reaction class
RC00001  C00003_C00004
RC00107  C00846_C02222
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K00217  maleylacetate reductase [EC:1.3.1.32]
Other DBs
RHEA: 16984

KEGG   REACTION: R02989
Entry
R02989                      Reaction                               

Name
3-oxoadipate:NADP+ oxidoreductase
Definition
3-Oxoadipate + NADP+ <=> 2-Maleylacetate + NADPH + H+
Equation
Comment
NAD+ (see R02988)
Reaction class
RC00001  C00005_C00006
RC00107  C00846_C02222
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K00217  maleylacetate reductase [EC:1.3.1.32]
Other DBs
RHEA: 16988

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