KEGG   ORTHOLOGY: K00300
Entry
K00300                      KO                                     
Symbol
mtdA
Name
methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+) [EC:1.5.1.5 1.5.1.-]
Pathway
map00670  One carbon pool by folate
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01240  Biosynthesis of cofactors
Module
M00140  C1-unit interconversion, prokaryotes
Reaction
R01220  5,10-methylenetetrahydrofolate:NADP+ oxidoreductase
R08059  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     K00300  mtdA; methylenetetrahydrofolate/methylenetetrahydromethanopterin dehydrogenase (NADP+)
Other DBs
GO: 0004488
Genes
MCA: MCA0508
METU: GNH96_13770
MMEO: OOT43_08830
MMT: Metme_2715
MDN: JT25_018050
MDH: AYM39_08875
MKO: MKLM6_1850
METL: U737_08940
MPAD: KEF85_02440
MELL: IVG45_03000
MRP: NM686_010320
MMOT: QZJ86_11930
MAH: MEALZ_3221(mtdA)
MBUR: EQU24_04570
MPSY: CEK71_10730
MMAI: sS8_1023
MSZE: MSZNOR_0597(mtdA)
MMOB: F6R98_09875
MEIN: methR_P0717
MOZ: MoryE10_26120(mtdA)
MISZ: MishRS11D_20060(mtdA)
MESL: KKZ03_00280
MEIY: MIN45_P1256
MCAU: MIT9_P1269
MEJ: Q7A_616
MEC: Q7C_2202
MPIN: LGT42_000030
MMAF: GCM100_12060(mtdA)
MTHA: VSX76_03940
NHL: Nhal_3872
NWR: E3U44_04695
MPT: Mpe_A3259
METP: C1M51_05920
METR: BSY238_260(mtdA)
FMY: HO273_02495
MEA: Mex_1p1728(mtdA)
MDI: METDI2480(mtdA)
MEX: Mext_1797
MCH: Mchl_2133
MPO: Mpop_1749
MZA: B2G69_16645
MRD: Mrad2831_3668
MET: M446_6554
MNO: Mnod_7114
MOR: MOC_4192
META: Y590_08590
MAQU: Maq22A_c19275(mtdA)
MPHY: MCBMB27_03150
MEE: DA075_26530
METD: C0214_10355
METX: A3862_13145
METS: DK389_15335
METI: DK427_15530
MMES: MMSR116_21290
MTEA: DK419_14265
MIND: mvi_28910(mtdA)
MOG: MMB17_01125
MTAD: M6G65_20445
MLG: CWB41_15800
MEDK: QEV83_17980
MCG: GL4_3376
METG: HT051_02820
MSC: BN69_1176
MBRY: B1812_17515
MROS: EHO51_12210
MHEY: H2LOC_011830
MPAR: F7D14_09150
MIWA: SS37A_07140(mtdA)
MTW: CQW49_12210
MECQ: MSC49_04660(mtdA)
CMET: K6K41_15055
GBE: GbCGDNIH1_0050
GBH: GbCGDNIH2_0050
GBC: GbCGDNIH3_0050
GBS: GbCGDNIH4_0050
CMIC: caldi_15590(mtdA)
FWA: DCMF_03880
HAS: Halsa_0940
RBA: RB10295(mtdA)
PSL: Psta_2659
PIR: VN12_15785(mtdA)
RUL: UC8_11070(mtdA)
RML: FF011L_55010(mtdA)
MFF: MFFC18_24480(mtdA)
ROL: CA51_24720(mtdA)
RUV: EC9_20900(mtdA)
RCF: Poly24_24120(mtdA)
AHEL: Q31a_40210(mtdA)
LCRE: Pla8534_42860(mtdA)
AAGG: ETAA8_15630(mtdA)
BVO: Pan97_44440(mtdA)
BREM: PSR63_16255
RLC: K227x_52060(mtdA)
SMAM: Mal15_51970(mtdA)
SNEP: Enr13x_11870(mtdA)
LPAV: PLANPX_0555
LLH: I41_06160(mtdA)
AMUC: Pan181_45490(mtdA)
PND: Pla175_50930(mtdA)
AMOB: HG15A2_07270(mtdA)
PLM: Plim_3754
PEH: Spb1_04100(mtdA)
PBS: Plabr_0088
PLS: VT03_31910(mtdA)
PLH: VT85_19965(mtdA)
FMR: Fuma_03860(mtdA)
GMR: GmarT_10990(mtdA)
GIM: F1728_09270
GPN: Pan110_10790(mtdA)
GFM: Enr17x_11800(mtdA)
MRI: Mal4_08500(mtdA)
SDYN: Mal52_22850(mtdA)
PLON: Pla110_21490(mtdA)
ACAF: CA12_34250(mtdA)
SVP: Pan189_25060(mtdA)
TPOL: Mal48_43430(mtdA)
CHYA: V22_25580(mtdA)
CCOS: Pan44_04630(mtdA)
PVAR: SH412_003218
CCOP: Mal65_19270(mtdA)
GES: VT84_01765(mtdA)
GOG: C1280_25115
GMS: SOIL9_75900
TIM: GMBLW1_35630
LRS: PX52LOC_00082
FTJ: FTUN_3065
ULI: ETAA1_52350(mtdA)
TSPH: KIH39_14270
IPA: Isop_1012
SACI: Sinac_4955
PBOR: BSF38_04914(mtdA)
AGV: OJF2_60600(mtdA)
AMO: Anamo_1147
ARAM: KAR29_10190
 » show all
Reference
PMID:8144463
  Authors
Chistoserdova LV, Lidstrom ME
  Title
Genetics of the serine cycle in Methylobacterium extorquens AM1: identification of sgaA and mtdA and sequences of sgaA, hprA, and mtdA.
  Journal
J Bacteriol 176:1957-68 (1994)
DOI:10.1128/JB.176.7.1957-1968.1994
  Sequence
[mea:Mex_1p1728]
Reference
PMID:9765566
  Authors
Vorholt JA, Chistoserdova L, Lidstrom ME, Thauer RK
  Title
The NADP-dependent methylene tetrahydromethanopterin dehydrogenase in Methylobacterium extorquens AM1.
  Journal
J Bacteriol 180:5351-6 (1998)
DOI:10.1128/JB.180.20.5351-5356.1998
  Sequence
[mea:Mex_1p1728]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (516)   
   KEGG GENES (133)   
   KEGG MGENES (382)   
   OC (1)   
All databases (533)   

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