KEGG   ORTHOLOGY: K00399Help
Entry
K00399                      KO                                     

Name
mcrA
Definition
methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00399  mcrA; methyl-coenzyme M reductase alpha subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.1  coenzyme-B sulfoethylthiotransferase
     K00399  mcrA; methyl-coenzyme M reductase alpha subunit
BRITE hierarchy
Other DBs
RN: R04541
GO: 0050524
Genes
MJA: MJ_0083 MJ_0846
MFE: Mefer_0938
MVU: Metvu_0149 Metvu_1194
MFS: MFS40622_0424 MFS40622_1315
MIF: Metin_0281
MJH: JH146_0503 JH146_1056
MIG: Metig_0445 Metig_1237
MMP: MMP1559(mcrA)
MMQ: MmarC5_0017
MMX: MmarC6_1111
MMD: GYY_08645
MAE: Maeo_1268
MVO: Mvol_1128
MMG: MTBMA_c15120(mrtA) MTBMA_c15480(mcrA)
MWO: MWSIV6_1521(mrtA) MWSIV6_1556(mcrA)
MST: Msp_0321(mrtA)
MRU: mru_1924(mcrA)
MEB: Abm4_1526(mcrA)
MMIL: sm9_1353(mrtA) sm9_2027(mcrA)
MEYE: TL18_09320
METH: MBMB1_1682(mcrA) MBMB1_1825(mrtA)
MFC: BRM9_0935(mcrA) BRM9_2156(mrtA)
MFI: DSM1535_0905(mcrA) DSM1535_1095(mrtA)
MCUB: MCBB_1985(mcrA)
METT: CIT01_01115(mcrA) CIT01_03630(mcrA)
METO: CIT02_08450(mcrA) CIT02_09480(mcrA)
MKA: MK0655(mcrA)
MEAR: Mpt1_c02010(mcrA)
MARC: AR505_1396
MAC: MA_4546
MBAR: MSBR2_2279
MBAK: MSBR3_2340
MMA: MM_1240
MMAC: MSMAC_0072
METM: MSMTP_0100
MTHE: MSTHC_1645
MTHR: MSTHT_1644
MHOR: MSHOH_0084
MFZ: AOB57_007335(mcrA)
MBU: Mbur_2417(mcrA)
MMET: MCMEM_0559
MMH: Mmah_0612
MPY: Mpsy_0828
MTP: Mthe_0569
MCJ: MCON_0759(mcrA)
MHI: Mhar_0498
MHU: Mhun_2148
MBG: BN140_1521(mcrA1) BN140_1738(mcrA3)
MEMA: MMAB1_1952(mcrA) MMAB1_2235(mcrA)
MBN: Mboo_0582
MPL: Mpal_2309
MPD: MCP_0516(mcrA)
MEZ: Mtc_0908(mcrA)
RCI: RCIX2063(mcrA)
BARC: AOA65_0408(mcrA)
BARB: AOA66_1761(mcrA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9367957
  Authors
Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK
  Title
Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.
  Journal
Science 278:1457-62 (1997)
DOI:10.1126/science.278.5342.1457
  Sequence

KEGG   ORTHOLOGY: K00401Help
Entry
K00401                      KO                                     

Name
mcrB
Definition
methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00401  mcrB; methyl-coenzyme M reductase beta subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.1  coenzyme-B sulfoethylthiotransferase
     K00401  mcrB; methyl-coenzyme M reductase beta subunit
BRITE hierarchy
Other DBs
RN: R04541
GO: 0050524
Genes
MJA: MJ_0081 MJ_0842
MFE: Mefer_0934
MVU: Metvu_0145 Metvu_1192
MFS: MFS40622_0426 MFS40622_1319
MIF: Metin_0285
MJH: JH146_0505 JH146_1060
MIG: Metig_0442 Metig_1233
MMP: MMP1555(mcrB)
MMQ: MmarC5_0021
MMX: MmarC6_1115
MMD: GYY_08625
MAE: Maeo_1264
MVO: Mvol_1124
MMG: MTBMA_c15150(mrtB) MTBMA_c15520(mcrB)
MWO: MWSIV6_1524(mrtB) MWSIV6_1560(mcrB)
MST: Msp_0318(mrtB)
MRU: mru_1928(mcrB)
MEB: Abm4_1530(mcrB)
MMIL: sm9_1356(mrtB) sm9_2031(mcrB)
MEYE: TL18_09340
METH: MBMB1_1686(mcrB) MBMB1_1822(mrtB)
MFC: BRM9_0939(mcrB) BRM9_2153(mrtB)
MFI: DSM1535_0909(mcrB) DSM1535_1092(mrtB)
MCUB: MCBB_1989(mcrB)
METT: CIT01_01100(mcrB) CIT01_03650(mcrB)
METO: CIT02_08465(mcrB) CIT02_09460(mcrB)
MKA: MK0651(mcrB)
MEAR: Mpt1_c01980(mcrB)
MARC: AR505_1399
MAC: MA_4550
MBAR: MSBR2_2283
MBAK: MSBR3_2344
MMA: MM_1244
MMAC: MSMAC_0068
METM: MSMTP_0096
MTHE: MSTHC_1649
MTHR: MSTHT_1640
MHOR: MSHOH_0080
MFZ: AOB57_007315(mcrB)
MBU: Mbur_2421(mcrB)
MMET: MCMEM_0563
MMH: Mmah_0616
MPY: Mpsy_0832
MTP: Mthe_0572
MCJ: MCON_0762(mcrB)
MHI: Mhar_0495
MHU: Mhun_2144
MBG: BN140_1524(mcrB1) BN140_1734(mcrB3)
MBN: Mboo_0586
MPL: Mpal_2305
MPD: MCP_0512(mcrB)
MEZ: Mtc_0904(mcrB)
RCI: RCIX2059(mcrB)
BARC: AOA65_0406(mrtB)
BARB: AOA66_1769(mrtB)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9367957
  Authors
Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK
  Title
Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.
  Journal
Science 278:1457-62 (1997)
DOI:10.1126/science.278.5342.1457
  Sequence

KEGG   ORTHOLOGY: K00402Help
Entry
K00402                      KO                                     

Name
mcrG
Definition
methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00402  mcrG; methyl-coenzyme M reductase gamma subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.1  coenzyme-B sulfoethylthiotransferase
     K00402  mcrG; methyl-coenzyme M reductase gamma subunit
BRITE hierarchy
Other DBs
RN: R04541
GO: 0050524
Genes
MJA: MJ_0082 MJ_0845
MFE: Mefer_0937
MVU: Metvu_0148 Metvu_1193
MFS: MFS40622_0425 MFS40622_1316
MIF: Metin_0282
MJH: JH146_0504 JH146_1057
MIG: Metig_0444 Metig_1236
MMP: MMP1558(mcrG)
MMQ: MmarC5_0018
MMX: MmarC6_1112
MMD: GYY_08640
MAE: Maeo_1267
MVO: Mvol_1127
MMG: MTBMA_c15130(mrtG) MTBMA_c15490(mcrG)
MWO: MWSIV6_1522(mrtG) MWSIV6_1557(mcrG)
MST: Msp_0320(mrtG)
MRU: mru_1925(mcrG)
MEB: Abm4_1527(mcrG)
MMIL: sm9_1354(mrtG) sm9_2028(mcrG)
MEYE: TL18_09325
METH: MBMB1_1683(mcrG) MBMB1_1824(mrtG)
MFC: BRM9_0936(mcrG) BRM9_2155(mrtG)
MFI: DSM1535_0906(mcrG) DSM1535_1094(mrtG)
MCUB: MCBB_1986(mcrG)
METT: CIT01_01110(mcrG) CIT01_03635(mcrG)
METO: CIT02_08455(mcrG) CIT02_09475(mcrG)
MKA: MK0654(mcrG)
MEAR: Mpt1_c02000(mrtG)
MARC: AR505_1397
MAC: MA_4547
MBAR: MSBR2_2280
MBAK: MSBR3_2341
MMA: MM_1241
MMAC: MSMAC_0071
METM: MSMTP_0099
MTHE: MSTHC_1646
MTHR: MSTHT_1643
MHOR: MSHOH_0083
MFZ: AOB57_007330(mcrG)
MBU: Mbur_2418(mcrG)
MMET: MCMEM_0560
MMH: Mmah_0613
MPY: Mpsy_0829
MTP: Mthe_0570
MCJ: MCON_0760(mcrG)
MHI: Mhar_0497
MHU: Mhun_2147
MBG: BN140_1522(mcrG1) BN140_1737(mcrG3)
MEMA: MMAB1_1953(mcrG) MMAB1_2234(mcrG)
MBN: Mboo_0583
MPL: Mpal_2308
MPD: MCP_0515(mcrG)
MEZ: Mtc_0907(mcrG)
RCI: RCIX2062(mcrG)
BARC: AOA65_0407(mcrG)
BARB: AOA66_1770(mcrG)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9367957
  Authors
Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK
  Title
Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation.
  Journal
Science 278:1457-62 (1997)
DOI:10.1126/science.278.5342.1457
  Sequence

KEGG   REACTION: R04541Help
Entry
R04541                      Reaction                               

Name
2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase
Definition
Coenzyme B + 2-(Methylthio)ethanesulfonate <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Methane
Equation
Reaction class
RC00011  C04628_C04832
RC01542  C01438_C03920
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Orthology
K00399  methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
K00401  methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
K00402  methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
Other DBs
RHEA: 12535

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