KEGG   ORTHOLOGY: K00431Help
Entry
K00431                      KO                                     

Name
TPO
Definition
thyroid peroxidase [EC:1.11.1.8]
Pathway
ko00350  Tyrosine metabolism
ko01100  Metabolic pathways
ko04918  Thyroid hormone synthesis
ko05320  Autoimmune thyroid disease
Module
M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Disease
H00251  Thyroid dyshormonogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K00431  TPO; thyroid peroxidase
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    K00431  TPO; thyroid peroxidase
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K00431  TPO; thyroid peroxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     K00431  TPO; thyroid peroxidase
BRITE hierarchy
Other DBs
RN: R03208 R03539 R03953 R03973
GO: 0004447
Genes
HSA: 7173(TPO)
PTR: 112208205(TPO)
PPS: 100996140(TPO)
GGO: 101154382(TPO)
PON: 100456793(TPO)
NLE: 100600125(TPO) 115834294
MCC: 721610(TPO)
MCF: 102125126(TPO)
CSAB: 103220948(TPO)
RRO: 104680243(TPO)
RBB: 108520786(TPO)
CJC: 100386952(TPO)
SBQ: 101037216(TPO)
MMU: 22018(Tpo)
MCAL: 110307221(Tpo)
MPAH: 110324682(Tpo)
RNO: 54314(Tpo)
CGE: 100774668(Tpo)
NGI: 103747657(Tpo)
HGL: 101704548(Tpo)
CCAN: 109698840(Tpo)
OCU: 100358662(TPO)
TUP: 102498362(TPO)
CFA: 403521(TPO)
VVP: 112927779(TPO)
AML: 100482359(TPO)
UMR: 103659385(TPO)
UAH: 113269244(TPO)
ORO: 101386003(TPO)
ELK: 111154148
FCA: 101098706(TPO)
PTG: 102968585(TPO)
PPAD: 109258749(TPO)
AJU: 106970832(TPO)
BTA: 525013(TPO)
BOM: 102270919(TPO)
BBUB: 102407971(TPO) 112582646
CHX: 102182976(TPO)
OAS: 105606468(TPO)
SSC: 445522(TPO)
CFR: 102509347(TPO)
CDK: 105105788(TPO)
BACU: 103019738(TPO)
LVE: 103068590(TPO)
OOR: 101277595(TPO)
DLE: 111167991(TPO)
PCAD: 102992243(TPO)
ECB: 100072955(TPO)
EPZ: 103558875(TPO)
EAI: 106831426(TPO)
MYB: 102261673(TPO)
MYD: 102752073(TPO)
MNA: 107526670(TPO)
HAI: 109384713(TPO)
DRO: 112298003(TPO)
PALE: 102894645(TPO)
RAY: 107516248(TPO)
MJV: 108410043(TPO)
LAV: 100654315(TPO)
TMU: 101356790
MDO: 100032350(TPO)
SHR: 100914346(TPO) 100922174
PCW: 110193820(TPO)
OAA: 100080616(TPO)
GGA: 776120(TPO)
MGP: 100547103(TPO)
CJO: 107312163(TPO)
NMEL: 110396710(TPO)
APLA: 101799650(TPO)
ACYG: 106030804(TPO)
TGU: 100218312(TPO)
LSR: 110482186(TPO)
SCAN: 103822861(TPO)
GFR: 102035753(TPO)
FAB: 101810932(TPO)
PHI: 102101957(TPO)
PMAJ: 107202328(TPO)
CCAE: 111926044(TPO)
CCW: 104685517(TPO)
ETL: 114069616(TPO)
FPG: 101922364(TPO)
FCH: 102045733(TPO)
CLV: 102095211(TPO)
EGZ: 104122160(TPO)
NNI: 104013841(TPO)
ACUN: 113477604(TPO)
PADL: 103921358(TPO)
AAM: 106492987(TPO)
ASN: 102375780(TPO)
AMJ: 106736998(TPO)
PSS: 102447524(TPO)
CMY: 102940210(TPO)
CPIC: 101932866(TPO)
ACS: 100562991(tpo)
PVT: 110073409(TPO)
PBI: 103055216(TPO)
PMUR: 107288276(TPO)
TSR: 106551315(TPO)
PMUA: 114593754(TPO) 114600521
GJA: 107108843 107120374(TPO)
XLA: 100049788(tpo.S)
XTR: 100036738(tpo)
NPR: 108789262(TPO)
DRE: 100331172(epx) 569363(tpo)
SRX: 107707791(tpo)
SANH: 107678715(tpo) 107701038
SGH: 107594129
IPU: 108269580(tpo) 108274988
PHYP: 113529680 113538844(tpo)
AMEX: 103026466 103032699(tpo)
EEE: 113572650(tpo) 113583564
LCO: 104928854 104934649(tpo)
MZE: 101470734(tpo) 101472649
ONL: 100692514 100700906(tpo)
OLA: 101167362 105356959(tpo)
CVG: 107100628
NFU: 107388669 107392598(tpo)
KMR: 108230067 108241739(tpo)
ALIM: 106521174 106521219(tpo)
AOCE: 111562581(tpo) 111584102
CSEM: 103379991(tpo) 103380299
POV: 109624077 109627948(tpo)
SDU: 111226032(tpo)
BPEC: 110155374(tpo) 110169467
MALB: 109965011(tpo) 109972931
SASA: 106584777 106611389(tpo)
OTW: 112256946(tpo)
SALP: 112069494(tpo)
ELS: 105028745(tpo) 105029701
SFM: 108942507(tpo)
PKI: 111848005 111857914(tpo)
LCM: 102362813(TPO)
CMK: 103175078 103185975(tpo)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1497352
  Authors
Rawitch AB, Pollock G, Yang SX, Taurog A
  Title
Thyroid peroxidase glycosylation: the location and nature of the N-linked oligosaccharide units in porcine thyroid peroxidase.
  Journal
Arch Biochem Biophys 297:321-7 (1992)
DOI:10.1016/0003-9861(92)90679-Q
  Sequence
[ssc:445522]
Reference
  Authors
Ruf J, Carayon P
  Title
Structural and functional aspects of thyroid peroxidase.
  Journal
Arch Biochem Biophys 445:269-77 (2006)
DOI:10.1016/j.abb.2005.06.023

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