KEGG   ORTHOLOGY: K00695
Entry
K00695                      KO                                     

Name
E2.4.1.13
Definition
sucrose synthase [EC:2.4.1.13]
Pathway
ko00500  Starch and sucrose metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00500 Starch and sucrose metabolism
    K00695  E2.4.1.13; sucrose synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00695  E2.4.1.13; sucrose synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.13  sucrose synthase
     K00695  E2.4.1.13; sucrose synthase
Glycosyltransferases [BR:ko01003]
 Others
  Other glycosyltransferases
   K00695  E2.4.1.13; sucrose synthase
Other DBs
RN: R00806
GO: 0016157
CAZy: GT4
Genes
ATH: AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY: 9301791 9304569 9308917 9310083 9311669 9324989
CRB: 17877054 17877643 17881746 17882355 17887544 17895033
CSAT: 104702036 104706429 104707872 104712951 104713942 104719340 104723601 104724082 104725413 104732612 104736154 104737553 104751189 104763273 104770460
EUS: EUTSA_v10003667mg EUTSA_v10012719mg EUTSA_v10018094mg EUTSA_v10027639mg EUTSA_v10028435mg
BRP: 103830752 103831821 103836763 103845641 103856465 103868315 103875021
BNA: 106345241 106348876 106353704 106354279 106355952 106365510 106371709 106376588 106383535 106386990 106402327 106406752 106407384 106434916 106451551 111210221 111211726
BOE: 106296231 106296386 106296521 106304017 106318311 106319066 106336052
RSZ: 108814119 108814255 108817509 108823863 108828189 108847491 108852315
THJ: 104799606 104805659 104810983 104812185 104825963 104827331
LJA: Lj0g3v0242009.1(Lj0g3v0242009.1) Lj1g3v4875640.1(Lj1g3v4875640.1) Lj1g3v4875640.2(Lj1g3v4875640.2) Lj2g3v2507780.1(Lj2g3v2507780.1) Lj3g3v1238910.1(Lj3g3v1238910.1) Lj4g3v2215210.1(Lj4g3v2215210.1) Lj6g3v1162830.1(Lj6g3v1162830.1) Lj6g3v1162830.2(Lj6g3v1162830.2) Lj6g3v1468270.2(Lj6g3v1468270.2)
DOSA: Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
ATS: 109740648(LOC109740648) 109744619(LOC109744619) 109746065(LOC109746065) 109749305(LOC109749305) 109759549(LOC109759549) 109766888(LOC109766888) 109779202(LOC109779202)
MNG: MNEG_8846
MMAI: sS8_2015
NOC: Noc_3068
NHL: Nhal_3940
NWA: Nwat_3123
TEE: Tel_14610
TGR: Tgr7_0177
NEU: NE1214(ss2)
NET: Neut_1079
SPLB: SFPGR_05660(spsA)
AFR: AFE_1552
ACU: Atc_1727
TEL: tlr1047
THN: NK55_01920(spsA)
AMR: AM1_6048
GVI: gvip490(spsA)
GLJ: GKIL_2834
ANA: all1059 all4985(susA)
NSH: GXM_00252
NAZ: Aazo_0215
ANB: ANA_C11946(susA)
CTHE: Chro_5323
MRO: MROS_1314
 » show all
Reference
PMID:8220487
  Authors
Martin T, Frommer WB, Salanoubat M, Willmitzer L
  Title
Expression of an Arabidopsis sucrose synthase gene indicates a role in metabolization of sucrose both during phloem loading and in sink organs.
  Journal
Plant J 4:367-77 (1993)
DOI:10.1046/j.1365-313X.1993.04020367.x
  Sequence
[ath:AT5G20830]
Reference
  Authors
Bieniawska Z, Paul Barratt DH, Garlick AP, Thole V, Kruger NJ, Martin C, Zrenner R, Smith AM
  Title
Analysis of the sucrose synthase gene family in Arabidopsis.
  Journal
Plant J 49:810-28 (2007)
DOI:10.1111/j.1365-313X.2006.03011.x

KEGG   ENZYME: 2.4.1.13
Entry
EC 2.4.1.13                 Enzyme                                 

Name
sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase;
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
NDP-alpha-D-glucose:D-fructose 2-alpha-D-glucosyltransferase (configuration-retaining)
Reaction(IUBMB)
NDP-alpha-D-glucose + D-fructose = NDP + sucrose [RN:R07256]
Reaction(KEGG)
R07256 > R00806 R06036(G) R08676
Substrate
NDP-alpha-D-glucose [CPD:C15541];
D-fructose [CPD:C00095]
Product
NDP [CPD:C00454];
sucrose [CPD:C00089]
Comment
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
History
EC 2.4.1.13 created 1961, modified 2003
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00695  sucrose synthase
Genes
ATH: AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY: 9301791 9304569 9308917 9310083 9311669 9324989
CRB: 17877054 17877643 17881746 17882355 17887544 17895033
CSAT: 104702036 104706429 104707872 104712951 104713942 104719340 104723601 104724082 104725413 104732612 104736154 104737553 104751189 104763273 104770460
EUS: EUTSA_v10003667mg EUTSA_v10012719mg EUTSA_v10018094mg EUTSA_v10027639mg EUTSA_v10028435mg
BRP: 103830752 103831821 103836763 103845641 103856465 103868315 103875021
BNA: 106345241 106348876 106353704 106354279 106355952 106365510 106371709 106376588 106383535 106386990 106402327 106406752 106407384 106434916 106451551 111210221 111211726
BOE: 106296231 106296386 106296521 106304017 106318311 106319066 106336052
RSZ: 108814119 108814255 108817509 108823863 108828189 108847491 108852315
THJ: 104799606 104805659 104810983 104812185 104825963 104827331
LJA: Lj0g3v0242009.1(Lj0g3v0242009.1) Lj1g3v4875640.1(Lj1g3v4875640.1) Lj1g3v4875640.2(Lj1g3v4875640.2) Lj2g3v2507780.1(Lj2g3v2507780.1) Lj3g3v1238910.1(Lj3g3v1238910.1) Lj4g3v2215210.1(Lj4g3v2215210.1) Lj6g3v1162830.1(Lj6g3v1162830.1) Lj6g3v1162830.2(Lj6g3v1162830.2) Lj6g3v1468270.2(Lj6g3v1468270.2)
DOSA: Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
ATS: 109740648(LOC109740648) 109744619(LOC109744619) 109746065(LOC109746065) 109749305(LOC109749305) 109759549(LOC109759549) 109766888(LOC109766888) 109779202(LOC109779202)
MNG: MNEG_8846
MMAI: sS8_2015
NOC: Noc_3068
NHL: Nhal_3940
NWA: Nwat_3123
TEE: Tel_14610
TGR: Tgr7_0177
NEU: NE1214(ss2)
NET: Neut_1079
SPLB: SFPGR_05660(spsA)
AFR: AFE_1552
ACU: Atc_1727
TEL: tlr1047
THN: NK55_01920(spsA)
AMR: AM1_6048
GVI: gvip490(spsA)
GLJ: GKIL_2834
ANA: all1059 all4985(susA)
NSH: GXM_00252
NAZ: Aazo_0215
ANB: ANA_C11946(susA)
CTHE: Chro_5323
MRO: MROS_1314
 » show all
Reference
1
  Authors
Avigad, G. and Milner, Y.
  Title
UDP-glucose:fructose transglucosylase from sugar beet roots.
  Journal
Methods Enzymol 8:341-345 (1966)
Reference
2  [PMID:14367373]
  Authors
CARDINI CE, LELOIR LF, CHIRIBOGA J.
  Title
The biosynthesis of sucrose.
  Journal
J Biol Chem 214:149-55 (1955)
Reference
3  [PMID:4624446]
  Authors
Delmer DP.
  Title
The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.
  Journal
J Biol Chem 247:3822-8 (1972)
Reference
4  [PMID:5941994]
  Authors
Murata T, Sugiyama T, Minamikawa T, Akazawa T.
  Title
Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.
  Journal
Arch Biochem Biophys 113:34-44 (1966)
DOI:10.1016/0003-9861(66)90153-6
Reference
5  [PMID:10050318]
  Authors
Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.
  Title
An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.
  Journal
Plant Cell Physiol 39:1337-41 (1998)
DOI:10.1093/oxfordjournals.pcp.a029339
Reference
6  [PMID:10592030]
  Authors
Porchia AC, Curatti L, Salerno GL.
  Title
Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.
  Journal
Planta 210:34-40 (1999)
DOI:10.1007/s004250050651
Reference
7  [PMID:16653008]
  Authors
Ross HA, Davies HV.
  Title
Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.
  Journal
Plant Physiol 100:1008-1013 (1992)
DOI:10.1104/pp.100.2.1008
Reference
8  [PMID:16661094]
  Authors
Silvius JE, Snyder FW.
  Title
Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.
  Journal
Plant Physiol 64:1070-1073 (1979)
DOI:10.1104/pp.64.6.1070
Reference
9  [PMID:10845453]
  Authors
Tanase K, Yamaki S.
  Title
Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.
  Journal
Plant Cell Physiol 41:408-14 (2000)
DOI:10.1093/pcp/41.4.408
Reference
10 [PMID:12773636]
  Authors
Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J.
  Title
Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.
  Journal
Plant Cell Physiol 44:500-9 (2003)
DOI:10.1093/pcp/pcg062
  Sequence
[sot:102577594]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.13
IUBMB Enzyme Nomenclature: 2.4.1.13
ExPASy - ENZYME nomenclature database: 2.4.1.13
BRENDA, the Enzyme Database: 2.4.1.13
CAS: 9030-05-1

KEGG   REACTION: R00806
Entry
R00806                      Reaction                               

Name
UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Definition
UDP-glucose + D-Fructose <=> UDP + Sucrose
Equation
Remark
Same as: R06036
Reaction class
RC00005  C00015_C00029
RC00028  C00089_C00095
RC02748  C00029_C00089
Enzyme
Pathway
rn00500  Starch and sucrose metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00695  sucrose synthase [EC:2.4.1.13]
Other DBs
RHEA: 55095

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