KEGG ORTHOLOGY: K00725

ORTHOLOGY: K00725

Entry

K00725                      KO

Symbol

B4GALNT1, GALGT

Name

(N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92]

Pathway

map00600

Sphingolipid metabolism

map00604

Glycosphingolipid biosynthesis - ganglio series

map01100

Metabolic pathways

Reaction

R05938

R05939

R05946

R05952

R12962

UDP-N-acetyl-D-galactosamine:lactosylceramide-sulfate N-acetyl-D-galactrosaminyltransferase

Disease

H00266

Hereditary spastic paraplegia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
  09107 Glycan biosynthesis and metabolism
   00604 Glycosphingolipid biosynthesis - ganglio series
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.92  (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
     K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Glycosyltransferases [BR:ko01003]
Glycan extension
  Glycolipid
   K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase

Other DBs

GO:

0003947

CAZy:

GT12

Genes

HSA:	2583(B4GALNT1)

PTR:	452021(B4GALNT1)

PPS:	100977739(B4GALNT1)

GGO:	101142085(B4GALNT1)

PON:	100441953(B4GALNT1)

PPYG:

129009866(B4GALNT1)

NLE:	100596890(B4GALNT1)

HMH:	116480854(B4GALNT1)

SSYN:

129465668(B4GALNT1)

MCC:	715317(B4GALNT1)

MCF:	101926458(B4GALNT1)

MTHB:

126930376

MNI:	105474096(B4GALNT1)

CSAB:

103238575(B4GALNT1)

CATY:

105587249(B4GALNT1)

PANU:

101005418(B4GALNT1)

TGE:	112634643(B4GALNT1)

MLEU:

105545605(B4GALNT1)

RRO:	104682353(B4GALNT1)

RBB:	108519702(B4GALNT1)

TFN:	117089870(B4GALNT1)

PTEH:

111541797(B4GALNT1)

CANG:

105500499(B4GALNT1)

CJC:	100387150(B4GALNT1)

SBQ:	101035356(B4GALNT1)

CIMI:

108309735(B4GALNT1)

ANAN:

105729103(B4GALNT1)

CSYR:

103263166(B4GALNT1)

MMUR:

105877987(B4GALNT1)

LCAT:

123639596(B4GALNT1)

PCOQ:

105818113(B4GALNT1)

OGA:	100958711(B4GALNT1)

MMU:	14421(B4galnt1)

MCAL:

110302844(B4galnt1)

MPAH:

110326328(B4galnt1)

RNO:	64828(B4galnt1)

MCOC:

116075819(B4galnt1)

ANU:	117696826(B4galnt1)

MUN:	110561316(B4galnt1)

CGE:	100764682(B4galnt1)

MAUA:

101833950(B4galnt1)

PROB:

127215677(B4galnt1)

PLEU:

114704807(B4galnt1)

MORG:

121457348(B4galnt1)

MFOT:

126514729

AAMP:

119803561(B4galnt1)

NGI:	103742903(B4galnt1)

HGL:	101705101(B4galnt1)

CPOC:

100719351(B4galnt1)

CCAN:

109686096(B4galnt1)

DORD:

105988581(B4galnt1)

DSP:	122124387(B4galnt1)

PLOP:

125362144(B4galnt1)

NCAR:

124983376

MMMA:

107140121(B4galnt1)

OCU:

100340284

OPI:	101527960(B4GALNT1)

TUP:	102495908(B4GALNT1)

GVR:	103594212(B4GALNT1)

CFA:	481129(B4GALNT1)

CLUD:

112677966(B4GALNT1)

VVP:	112922336(B4GALNT1)

VLG:	121491928(B4GALNT1)

NPO:	129512209(B4GALNT1)

AML:	100466312(B4GALNT1)

UMR:	103656939(B4GALNT1)

UAH:	113256372(B4GALNT1)

UAR:	123787304(B4GALNT1)

ELK:

111160216

LLV:

125106163

MPUF:

101692331(B4GALNT1)

MNP:	132019847(B4GALNT1)

MLK:	131838547(B4GALNT1)

NVS:	122891153(B4GALNT1)

ORO:	101384792(B4GALNT1)

EJU:	114214987(B4GALNT1)

ZCA:	113921972(B4GALNT1)

MLX:	118008424(B4GALNT1)

NSU:	110577856(B4GALNT1)

LWW:	102747686(B4GALNT1)

FCA:	101082581(B4GALNT1)

PYU:	121040864(B4GALNT1)

PCOO:

112863779(B4GALNT1)

PBG:	122473825(B4GALNT1)

PVIV:

125170476(B4GALNT1)

LRUF:

124502179

PTG:	102953164(B4GALNT1)

PPAD:

109270387(B4GALNT1)

PUC:

125919254

AJU:

106975837

HHV:	120248004(B4GALNT1)

BTA:	520159(B4GALNT1)

BOM:	102280706(B4GALNT1)

BIU:	109559314(B4GALNT1)

BBUB:

102409613(B4GALNT1)

BBIS:

104988128(B4GALNT1)

CHX:	102173266(B4GALNT1)

OAS:	101119388(B4GALNT1)

BTAX:

128047491(B4GALNT1)

ODA:	120857502(B4GALNT1)

CCAD:

122427339(B4GALNT1)

MBEZ:

129536857(B4GALNT1)

SSC:	100516440(B4GALNT1)

CFR:	102520114(B4GALNT1)

CBAI:

105062135(B4GALNT1)

CDK:	105100336(B4GALNT1)

VPC:	102530081(B4GALNT1)

BACU:

103016988(B4GALNT1)

BMUS:

118902610(B4GALNT1)

LVE:	103088237(B4GALNT1)

OOR:	101281173(B4GALNT1)

DLE:	111173830(B4GALNT1)

PCAD:

102983599(B4GALNT1)

PSIU:

116760689(B4GALNT1)

NASI:

112394238(B4GALNT1)

ECB:	100053616(B4GALNT1)

EPZ:	103559776(B4GALNT1)

EAI:	106833013(B4GALNT1)

MYB:	102244087(B4GALNT1)

MYD:	102760120(B4GALNT1)

MMYO:

118651334(B4GALNT1)

MLF:	102434516(B4GALNT1)

PKL:	118730266(B4GALNT1)

EFUS:

103292474(B4GALNT1)

MNA:	107546159(B4GALNT1)

DRO:	112319125(B4GALNT1)

SHON:

118975962(B4GALNT1)

AJM:	119035675(B4GALNT1)

PDIC:

114513768(B4GALNT1)

PHAS:

123812944(B4GALNT1)

MMF:	118623520(B4GALNT1)

PPAM:

129076029(B4GALNT1)

HAI:	109390763(B4GALNT1)

RFQ:	117028118(B4GALNT1)

PALE:

102880239(B4GALNT1)

PGIG:

120604959(B4GALNT1)

PVP:	105307389(B4GALNT1)

RAY:	107501518(B4GALNT1)

MJV:	108409979(B4GALNT1)

TOD:	119248098(B4GALNT1)

SARA:

101557033(B4GALNT1)

SETR:

126022225(B4GALNT1)

LAV:	100656175(B4GALNT1)

TMU:

101357477

ETF:	101655324(B4GALNT1)

DNM:	101433475(B4GALNT1)

MDO:	100031466(B4GALNT1)

GAS:	123250467(B4GALNT1)

SHR:	100913439(B4GALNT1)

AFZ:

127538920

PCW:	110210985(B4GALNT1)

TVP:	118851807(B4GALNT1)

OAA:	114814766(B4GALNT1)

CJO:	107325778(B4GALNT1)

NMEL:

110392007

LSR:	110481834(B4GALNT1)

PMOA:

120499532(B4GALNT1)

OTC:	121334272(B4GALNT1)

PRUF:

121356353(B4GALNT1)

OMA:	130265786(B4GALNT1)

PHI:	102104849(B4GALNT1)

ZLE:	135459182(B4GALNT1)

SVG:	106862641(B4GALNT1)

TALA:

116959221 122153816

AGEN:

126037399

RTD:	128903865(B4GALNT1)

AROW:

112961595(B4GALNT1)

ASN:	102384074(B4GALNT1)

AMJ:	102576374(B4GALNT1)

CPOO:

109324403(B4GALNT1)

CMY:	102936553(B4GALNT1)

CCAY:

125627745(B4GALNT1)

DCC:	119845978(B4GALNT1)

CPIC:

101945852(B4GALNT1)

TST:	117889048(B4GALNT1)

CABI:

116818857(B4GALNT1)

MRV:	120391165(B4GALNT1)

ACS:	100553349(b4galnt1)

ASAO:

132767715(B4GALNT1)

PVT:	110070599(B4GALNT1)

SUND:

121921249(B4GALNT1)

PBI:	103067514(B4GALNT1)

PMUR:

107294728(B4GALNT1)

CTIG:

120303310(B4GALNT1)

TSR:	106553723(B4GALNT1)

PGUT:

117666505(B4GALNT1)

APRI:

131190792(B4GALNT1)

PTEX:

113444822(B4GALNT1)

NSS:	113416181(B4GALNT1)

VKO:	123029881(B4GALNT1)

PMUA:

114592946(B4GALNT1)

PRAF:

128404881(B4GALNT1)

ZVI:	118078702(B4GALNT1)

HCG:	128342243(B4GALNT1)

GJA:	107120713(B4GALNT1)

STOW:

125428050(B4GALNT1)

EMC:	129346127(B4GALNT1)

XLA:	108709867(b4galnt1.S) 379299(b4galnt1.L)

XTR:	100145208(b4galnt1)

NPR:	108802621(B4GALNT1)

RTEM:

120929452(B4GALNT1)

BBUF:

120996074(B4GALNT1)

BGAR:

122932266(B4GALNT1)

MUO:	115465835(B4GALNT1)

GSH:	117356330(B4GALNT1)

DRE:	558684(b4galnt1a) 793635(b4galnt1b)

SRX:	107708855 107711068 107716216 107717192 107733607

SANH:

107667298 107667748 107673615 107681939 107695798

SGH:	107570598 107582708 107582953 107585207 107586541

CCAR:

109047493 109056959 109062280 109062741 109064114 109076424

CAUA:

113046700 113046702 113047614 113050355 113066542 113085425 113094168

CGIB:

127960243 128015731

PTET:

122329311(b4galnt1a) 122347215(b4galnt1b)

LROH:

127154383(b4galnt1a) 127167364(b4galnt1b)

OMC:	131531907(b4galnt1a) 131542433(b4galnt1b)

PPRM:

120463589(b4galnt1a) 120491381(b4galnt1b)

RKG:	130073611(b4galnt1a) 130087557(b4galnt1b)

MAMB:

125259537(b4galnt1a) 125273705(b4galnt1b)

CIDE:

127505109 127514749

MASI:

127420175 127446676 127448647

TROS:

130556534(b4galnt1b) 130571996(b4galnt1a)

TDW:	130409795(b4galnt1a) 130425150(b4galnt1b)

MANU:

129431030(b4galnt1a) 129450290(b4galnt1b)

IPU:	108272210(b4galnt1b) 108276385 108276386 108276500

IFU:	128614781(b4galnt1b) 128619252 128619300

PHYP:

113530618 113530674 113530881 113545817(b4galnt1)

SMEO:

124390265(b4galnt1b)

TFD:	113658252(b4galnt1a) 113660538(b4galnt1b)

TVC:	132844148(b4galnt1b) 132862228(b4galnt1a)

TRN:	134316624(b4galnt1b) 134333845(b4galnt1a)

AMEX:

103039726(b4galnt1b) 103043708(b4galnt1a)

CMAO:

118808252(b4galnt1b) 118822707(b4galnt1a)

EEE:	113567787(b4galnt1) 113589183

CHAR:

105897319(b4galnt1a)

TRU:	101063785 101064428(b4galnt1)

TFS:	130524298(b4galnt1b) 130530174(b4galnt1a)

TNG:	GSTEN00027252G001 GSTEN00027254G001 GSTEN00028095G001

LCO:	104931956(b4galnt1) 104932572

NCC:	104942127 104956934

TBEN:

117490021(b4galnt1b) 117494271(b4galnt1a)

CGOB:

115008865(b4galnt1) 115010627

PGEO:

117447391(b4galnt1b) 117449311(b4galnt1a)

GACU:

117541879(b4galnt1a) 117551053(b4galnt1b)

EMAC:

134871250(b4galnt1a) 134882602(b4galnt1b)

ELY:	117257558(b4galnt1b) 117258938(b4galnt1a)

EFO:	125889274(b4galnt1b) 125891661(b4galnt1a)

PLEP:

121939030 121946469(b4galnt1a) 121950679(b4galnt1b)

SLUC:

116039006(b4galnt1a) 116041660(b4galnt1b)

ECRA:

117943914(b4galnt1b) 117947769(b4galnt1a)

ESP:	116688378(b4galnt1) 116692690

PFLV:

114554065(b4galnt1) 114559465

GAT:	120829097(b4galnt1a) 120835599(b4galnt1b)

PPUG:

119223254 119229857(b4galnt1b)

AFB:	129099881(b4galnt1a) 129105782(b4galnt1b)

CLUM:

117731019(b4galnt1b) 117734202(b4galnt1a)

PSWI:

130199399(b4galnt1a) 130208867(b4galnt1b)

MSAM:

119886148(b4galnt1b) 119905488(b4galnt1a)

SCHU:

122867054(b4galnt1b) 122883091(b4galnt1a)

CUD:	121504305 121506149(b4galnt1b) 121518213(b4galnt1a)

ALAT:

119020492(b4galnt1b) 119023434(b4galnt1a)

MZE:	101478170 101483501 112434815

ONL:	100701263(b4galnt1) 100705425

OAU:	116325820(b4galnt1a) 116333850(b4galnt1b)

OLA:	101155420(b4galnt1) 101171003

OML:	112145405(b4galnt1b) 112159647(b4galnt1a)

CSAI:

133448753(b4galnt1b) 133457191(b4galnt1a)

XMA:	102222577 102228614 102235034

XCO:	114135118 114135952 114148900

XHE:	116710988 116710989 116727168

PRET:

103465386(b4galnt1) 103467344

PFOR:

103132481 103133123 103141140 103147665

PLAI:

106939363 106941044 106950804

PMEI:

106908770 106909689 106920821 106920822

GAF:	122832697(b4galnt1a) 122834697 122834726(b4galnt1b)

PPRL:

129357775(b4galnt1b) 129372481(b4galnt1a)

CVG:	107082147(b4galnt1) 107086793

CTUL:

119776671(b4galnt1b) 119782168

GMU:	124856483(b4galnt1b) 124861330(b4galnt1a)

NFU:	107385684(b4galnt1) 107390873

KMR:	108228644(b4galnt1a) 108235553(b4galnt1b)

ALIM:

106518031(b4galnt1) 106524945

NWH:	119412559(b4galnt1b) 119416969(b4galnt1a)

AOCE:

111566651(b4galnt1) 111587243

MCEP:

124996938(b4galnt1a) 125007198(b4galnt1b)

CSEM:

103385079 103385954(b4galnt1)

POV:	109629415(b4galnt1) 109630534

SSEN:

122768416(b4galnt1b) 122777098(b4galnt1a)

HHIP:

117761296(b4galnt1b) 117765024(b4galnt1a)

HSP:	118105510(b4galnt1b) 118111613(b4galnt1a)

PPLT:

128441744(b4galnt1a) 128452214(b4galnt1b)

SMAU:

118308945(b4galnt1b) 118316827(b4galnt1a)

LCF:	108876488(b4galnt1a) 108881464(b4galnt1b)

SDU:	111219289 111221963(b4galnt1)

SLAL:

111667834(b4galnt1) 111668982

XGL:	120783424(b4galnt1b) 120804023(b4galnt1a)

HCQ:	109522137(b4galnt1) 109531384

SSCV:

125976677 125988023

SBIA:

133505580(b4galnt1a) 133507139(b4galnt1b)

PEE:	133402341(b4galnt1a) 133409129(b4galnt1b)

PTAO:

133478538(b4galnt1a) 133483763(b4galnt1b)

BPEC:

110164780 110168375(b4galnt1)

MALB:

109968366 109972083

BSPL:

114856333(b4galnt1b) 114859002(b4galnt1a)

SJO:	128356009(b4galnt1b) 128357945(b4galnt1a)

SASA:

100306792(b4gn1) 106565528 106572659

STRU:

115150577 115165495 115207831

OTW:	112216357 112217564(b4galnt1b) 112254603

OMY:	110494320 110528114(b4galnt1b) 110532694

OGO:	124003500 124019822(b4galnt1b) 124032285

ONE:	115125666 115139823 115143172

OKI:	109891138 109904750 109907071

OKE:	118376214 118388567 118400293(b4galnt1b)

SALP:

111966771 111966811 111970082(b4galnt1)

SNH:	120058804 120061253 120065186

CCLU:

121537887 121575259 121577619

ELS:	105005742 105013542 105017218(b4galnt1)

SFM:	108918587(b4galnt1) 108939037

PKI:	111851086 111854415(b4galnt1) 111860628

AANG:

118207800 118211247(b4galnt1b)

LOC:	102693606(b4galnt1)

PSPA:

121308998(b4galnt1b)

ARUT:

117401004 117967072

PSEX:

120524830(b4galnt1b)

LCM:	102353417 102354362(B4GALNT1)

CMK:	103189519 103189521

CPLA:

122543394 122543431

HOC:	132805703 132805729

LERI:

129714719 129714721(b4galnt1b)

PMRN:

116944255 116946880 116946891 116951224

LRJ:	133344966 133344967 133345076

BFO:	118403673 118404274 118409104 118410769 118413253 118413880 118413881 118416384 118420990 118423730 118424548 118427545 118429972 118431016 118431239

BBEL:

109462277 109467557 109468930 109469051 109469639 109470355 109471463 109472103 109472932 109473331 109474378 109474463 109475330 109478673 109482281 109484300 109486291

SKO:	100366571 100366802 100367188 100367258 100367410 100367566 100368131 100369117 100369900 100372465 100374186 100377850 100377910 100378876 102804391

LAK:

106162682

» show all

Reference

PMID:7980468

Authors

Hidari JK, Ichikawa S, Furukawa K, Yamasaki M, Hirabayashi Y

Title

beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F.

Journal

Biochem J 303 ( Pt 3):957-65 (1994)
DOI:10.1042/bj3030957

Sequence

[rno:64828]

DBGET integrated database retrieval system