KEGG   ORTHOLOGY: K00731
Entry
K00731                      KO                                     

Name
C1GALT1
Definition
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]
Pathway
ko00512  Mucin type O-glycan biosynthesis
ko00514  Other types of O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00056  O-glycan biosynthesis, mucin type core
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00512 Mucin type O-glycan biosynthesis
    K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
   00514 Other types of O-glycan biosynthesis
    K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.122  N-acetylgalactosaminide beta-1,3-galactosyltransferase
     K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
Glycosyltransferases [BR:ko01003]
 Glycan extension
  Type 3 chain
   K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
Other DBs
RN: R05908
GO: 0016263
CAZy: GT31
Genes
HSA: 56913(C1GALT1)
PTR: 472288(C1GALT1)
PPS: 100977740(C1GALT1)
GGO: 101145951(C1GALT1)
PON: 100452461(C1GALT1)
NLE: 100583301(C1GALT1)
MCC: 696870(C1GALT1)
MCF: 102137839(C1GALT1)
CSAB: 103226504(C1GALT1)
RRO: 104668754(C1GALT1)
RBB: 108543414(C1GALT1)
CJC: 100406487(C1GALT1)
SBQ: 101029936(C1GALT1)
MMU: 94192(C1galt1)
MCAL: 110296408(C1galt1)
MPAH: 110316313(C1galt1)
RNO: 65044(C1galt1)
MUN: 110554784(C1galt1)
CGE: 100761169(C1galt1)
NGI: 103751705(C1galt1)
HGL: 101704643(C1galt1)
CCAN: 109703122(C1galt1)
OCU: 100359047(C1GALT1)
TUP: 102479007(C1GALT1)
CFA: 482314(C1GALT1)
VVP: 112923919(C1GALT1)
AML: 100483848(C1GALT1)
UMR: 103658758(C1GALT1)
UAH: 113260469(C1GALT1)
ORO: 101378420(C1GALT1)
ELK: 111147376
FCA: 101096459(C1GALT1)
PTG: 102965358(C1GALT1)
PPAD: 109263732(C1GALT1)
AJU: 106970015(C1GALT1)
BTA: 539417(C1GALT1)
BOM: 102287025(C1GALT1)
BIU: 109558238(C1GALT1)
BBUB: 102406993(C1GALT1)
CHX: 102169248(C1GALT1)
OAS: 101120567(C1GALT1)
SSC: 100525767(C1GALT1)
CFR: 102514986(C1GALT1)
CDK: 105088713(C1GALT1)
BACU: 103001219(C1GALT1)
LVE: 103071088(C1GALT1)
OOR: 101282789(C1GALT1)
DLE: 111181388(C1GALT1)
PCAD: 102983236(C1GALT1)
ECB: 100063865(C1GALT1)
EPZ: 103540682(C1GALT1)
EAI: 106839569(C1GALT1)
MYB: 102244854(C1GALT1) 102250159
MYD: 102754234(C1GALT1)
MNA: 107541729(C1GALT1)
HAI: 109394810(C1GALT1)
DRO: 112319804(C1GALT1)
PALE: 102883390(C1GALT1)
RAY: 107504471(C1GALT1)
MJV: 108406054(C1GALT1)
LAV: 100670784(C1GALT1)
TMU: 101357588
SHR: 100932643(C1GALT1)
PCW: 110217609(C1GALT1)
OAA: 103169736(C1GALT1)
GGA: 420575(C1GALT1)
MGP: 100542429(C1GALT1)
CJO: 107309116(C1GALT1)
NMEL: 110394018(C1GALT1)
APLA: 101797632(C1GALT1)
ACYG: 106037532(C1GALT1)
TGU: 100221974(C1GALT1)
LSR: 110474721(C1GALT1)
SCAN: 103812837(C1GALT1)
GFR: 102032158(C1GALT1)
FAB: 101810221(C1GALT1)
PHI: 102103229(C1GALT1) 102104490
PMAJ: 107199204 107200786(C1GALT1)
CCAE: 111924251(C1GALT1) 111944042
CCW: 104689153(C1GALT1)
ETL: 114073121(C1GALT1)
FPG: 101923797(C1GALT1)
FCH: 102059381(C1GALT1)
CLV: 102088254(C1GALT1)
EGZ: 104129130(C1GALT1)
ACUN: 113476756(C1GALT1)
PADL: 103922365(C1GALT1)
AAM: 106483404(C1GALT1) 106492776
AMJ: 102558826(C1GALT1) 102575907
PSS: 102460792(C1GALT1)
CPIC: 101931210 101942937(C1GALT1) 101945118
ACS: 100554192 100562160(c1galt1)
PVT: 110070539 110073023(C1GALT1)
PBI: 103050549(C1GALT1) 103063573
PMUR: 107283657(C1GALT1) 107288525
TSR: 106539635 106540395(C1GALT1)
PMUA: 114586421 114607087(C1GALT1)
XLA: 108707741 108708597 108708598 108709868 108709869 108718847(c1galt1.L) 108719911(c1galt1.S) 444326(LOC100496837.L)
DRE: 337131(c1galt1b) 555344(si:dkey-202e17.1) 557675(c1galt1a)
IPU: 108272220(c1galt1b) 108276279
PHYP: 113530505 113532793(c1galt1) 113545818
PRET: 103465384 103467345 103471939(c1galt1)
AOCE: 111566642 111575167(c1galt1) 111587244
CSEM: 103385080 103385956 103394502(c1galt1)
SLAL: 111667825 111668780(c1galt1) 111668905
BPEC: 110161213(c1galt1) 110164964 110168386
SFM: 108918317 108935659(c1galt1)
RTP: 109910639(c1galt1) 109927325
CIN: 100182788
DME: Dmel_CG2975(CG2975) Dmel_CG2983(CG2983) Dmel_CG3119(CG3119) Dmel_CG34056(CG34056) Dmel_CG34057(CG34057) Dmel_CG34451(CG34451) Dmel_CG34452(CG34452) Dmel_CG7440(tgy) Dmel_CG8708(CG8708) Dmel_CG9520(C1GalTA)
DSI: Dsimw501_GD10181(Dsim_GD10181) Dsimw501_GD12540(Dsim_GD12540) Dsimw501_GD12541(Dsim_GD12541) Dsimw501_GD13582(Dsim_GD13582) Dsimw501_GD22375(Dsim_GD22375) Dsimw501_GD22798(Dsim_GD22798) Dsimw501_GD23186(Dsim_GD23186) Dsimw501_GD23187(Dsim_GD23187) Dsimw501_GD24465(Dsim_GD24465) Dsimw501_GD27301(Dsim_GD27301)
PGC: 109856374
NVI: 100120600
BMOR: 101746328
PMAC: 106709178
PRAP: 110993263
HAW: 110374915
TNL: 113498994
API: 100168660
DNX: 107167669
AGS: 114122443
RMD: 113549883
BTAB: 109042199
ZNE: 110837984
CEL: CELE_C38H2.2(C38H2.2)
CBR: CBG18398
TSP: Tsp_00464
ADF: 107348169
AMIL: 114954137
PDAM: 113668011
SPIS: 111340814
DGT: 114516537
SMIN: v1.2.011019.t1(symbB.v1.2.011019.t1)
NGD: NGA_0449900(C1GALT1)
 » show all
Reference
  Authors
Ju T, Brewer K, D'Souza A, Cummings RD, Canfield WM
  Title
Cloning and expression of human core 1 beta1,3-galactosyltransferase.
  Journal
J Biol Chem 277:178-86 (2002)
DOI:10.1074/jbc.M109060200
  Sequence
[hsa:56913] [mmu:94192] [rno:65044] [cel:CELE_C38H2.2] [dme:Dmel_CG9520 Dmel_CG8708]

KEGG   ORTHOLOGY: K09653
Entry
K09653                      KO                                     

Name
C1GALT2, C1GALT1C1
Definition
C1GALT1-specific chaperone 1
Pathway
ko00512  Mucin type O-glycan biosynthesis
ko00514  Other types of O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00056  O-glycan biosynthesis, mucin type core
Disease
H01188  Tn syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00512 Mucin type O-glycan biosynthesis
    K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
   00514 Other types of O-glycan biosynthesis
    K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
Glycosyltransferases [BR:ko01003]
 Glycan extension
  Type 3 chain
   K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1
Other DBs
RN: R05908
CAZy: GT31
Genes
HSA: 29071(C1GALT1C1) 728819(C1GALT1C1L)
PTR: 465837(C1GALT1C1) 470362(C1GALT1C1L)
PPS: 100969207(C1GALT1C1) 100993655(C1GALT1C1L)
GGO: 101153425(C1GALT1C1L) 101154347(C1GALT1C1)
PON: 100441547(C1GALT1C1) 100455277(C1GALT1C1L)
NLE: 100594094(C1GALT1C1) 100600573(C1GALT1C1L)
MCC: 696662(C1GALT1C1) 704348(C1GALT1C1L)
MCF: 102121635(C1GALT1C1) 102123662(C1GALT1C1L)
CSAB: 103220384(C1GALT1C1L) 103247362(C1GALT1C1)
RRO: 104655320(C1GALT1C1) 104677528(C1GALT1C1L)
RBB: 108522508(C1GALT1C1L) 108534997(C1GALT1C1)
CJC: 100397132(C1GALT1C1) 100407249(C1GALT1C1L)
SBQ: 101029155(C1GALT1C1) 101033048
MMU: 59048(C1galt1c1)
MCAL: 110287544(C1galt1c1) 110295384
MPAH: 110313761(C1galt1c1) 110331014
RNO: 302499(C1galt1c1)
MUN: 110540456 110542264(C1galt1c1)
CGE: 100751243(C1galt1c1) 100770484 107978234(C1galt1c1l)
NGI: 103734858(C1galt1c1) 103738647
HGL: 101713150(C1galt1c1) 101721187(C1galt1c1l)
CCAN: 109682265(C1galt1c1l) 109697980(C1galt1c1)
OCU: 100340186(C1GALT1C1)
TUP: 102468879 102491240(C1GALT1C1)
CFA: 100685864(C1GALT1C1) 106559390(C1GALT1C1L)
VVP: 112915360(C1GALT1C1L) 112934431(C1GALT1C1)
AML: 100477728(C1GALT1C1) 105241450(C1GALT1C1L)
UMR: 103680219(C1GALT1C1)
UAH: 113246365(C1GALT1C1L) 113270915(C1GALT1C1)
ORO: 101379245(C1GALT1C1) 105757396(C1GALT1C1L)
FCA: 101088470(C1GALT1C1) 105260436(C1GALT1C1L)
PTG: 102964672(C1GALT1C1) 107181133(C1GALT1C1L)
PPAD: 109245084(C1GALT1C1L) 109250734(C1GALT1C1)
AJU: 106976946(C1GALT1C1L) 106986123(C1GALT1C1)
BTA: 523130 531644(C1GALT1C1)
BOM: 102277714 102280471(C1GALT1C1)
BIU: 109555431(C1GALT1C1)
BBUB: 102393574 102396728(C1GALT1C1)
CHX: 102178896 102191681(C1GALT1C1) 106502602(C1GALT1C1L)
OAS: 101114753(C1GALT1C1) 101116443 105606947(C1GALT1C1L) 114113876
SSC: 100511613(C1GALT1C1) 100622121
CFR: 102505035(C1GALT1C1L) 102514172(C1GALT1C1)
CDK: 105098889(C1GALT1C1) 105103553(C1GALT1C1L)
BACU: 103004134(C1GALT1C1)
LVE: 103086761(C1GALT1C1)
OOR: 101288367 101289050(C1GALT1C1) 105748970(C1GALT1C1L)
DLE: 111168238(C1GALT1C1)
PCAD: 102975797(C1GALT1C1)
ECB: 100055183(C1GALT1C1) 106781672(C1GALT1C1L)
EPZ: 103564259(C1GALT1C1)
EAI: 106824852(C1GALT1C1)
MYB: 102247302(C1GALT1C1)
MYD: 102758844(C1GALT1C1)
MNA: 107527927 107530353(C1GALT1C1L) 107537939(C1GALT1C1) 107541221
HAI: 109377056(C1GALT1C1)
DRO: 112310610(C1GALT1C1)
PALE: 102893352(C1GALT1C1)
MJV: 108395199(C1GALT1C1L) 108404399(C1GALT1C1)
LAV: 100657957 100659442(C1GALT1C1) 100661085(C1GALT1C1L)
MDO: 100012412(C1GALT1C1)
SHR: 100934128(C1GALT1C1)
PCW: 110200039(C1GALT1C1)
OAA: 100078534(C1GALT1C1)
GGA: 422362(C1GALT1C1)
MGP: 100543008(C1GALT1C1)
CJO: 107312958(C1GALT1C1)
NMEL: 110403151(C1GALT1C1)
ACYG: 106038520(C1GALT1C1)
TGU: 100226069(C1GALT1C1)
LSR: 110480433(C1GALT1C1)
SCAN: 103816390(C1GALT1C1)
GFR: 102039236(C1GALT1C1)
FAB: 101822119(C1GALT1C1)
PHI: 102113760(C1GALT1C1)
PMAJ: 107203805(C1GALT1C1)
CCAE: 111928667(C1GALT1C1)
CCW: 104694438(C1GALT1C1)
ETL: 114064876(C1GALT1C1)
FPG: 101910597(C1GALT1C1)
FCH: 102058870(C1GALT1C1)
CLV: 102088872(C1GALT1C1)
EGZ: 104124097(C1GALT1C1)
NNI: 104019093(C1GALT1C1)
ACUN: 113479905(C1GALT1C1)
PADL: 103922646(C1GALT1C1)
AAM: 106487564(C1GALT1C1)
ASN: 102373998(C1GALT1C1)
AMJ: 102570067(C1GALT1C1)
PSS: 102451481(C1GALT1C1)
CMY: 102939289(C1GALT1C1)
CPIC: 101934734(C1GALT1C1)
ACS: 100564289(c1galt1c1)
PVT: 110089992(C1GALT1C1)
PBI: 103055150(C1GALT1C1)
PMUR: 107302753(C1GALT1C1)
TSR: 106556084(C1GALT1C1)
PMUA: 114589001(C1GALT1C1)
GJA: 107123730
XLA: 108700090(c1galt1c1.S) 495031(c1galt1c1.L)
XTR: 448225(c1galt1c1)
NPR: 108789936(C1GALT1C1)
DRE: 324052(c1galt1c1)
SGH: 107550742(c1galt1c1) 107561475
IPU: 108269324(c1galt1c1)
PHYP: 113528710(c1galt1c1)
AMEX: 103021755(c1galt1c1)
EEE: 113582674(c1galt1c1)
TRU: 101078099(c1galt1c1)
LCO: 104919863(c1galt1c1)
NCC: 104941336(c1galt1c1)
MZE: 101481901(c1galt1c1)
ONL: 100694593(c1galt1c1)
OLA: 101161898(c1galt1c1)
XMA: 102236738(c1galt1c1)
XCO: 114139080(c1galt1c1)
PRET: 103471558(c1galt1c1)
CVG: 107093337(c1galt1c1)
NFU: 107378007(c1galt1c1)
KMR: 108231219(c1galt1c1)
ALIM: 106514755(c1galt1c1)
AOCE: 111570112(c1galt1c1)
CSEM: 103390551(c1galt1c1)
POV: 109627113(c1galt1c1)
LCF: 108895421(c1galt1c1)
SDU: 111232603(c1galt1c1)
SLAL: 111648273(c1galt1c1)
HCQ: 109518784(c1galt1c1)
BPEC: 110158967(c1galt1c1)
ELS: 105025618(c1galt1c1)
SFM: 108923010(c1galt1c1) 108930988
PKI: 111838014 111855479(c1galt1c1)
LCM: 102362156(C1GALT1C1)
CMK: 103178564(c1galt1c1)
API: 100570371
DNX: 107170403
 » show all
Reference
  Authors
Kudo T, Iwai T, Kubota T, Iwasaki H, Takayma Y, Hiruma T, Inaba N, Zhang Y, Gotoh M, Togayachi A, Narimatsu H
  Title
Molecular cloning and characterization of a novel UDP-Gal:GalNAc(alpha) peptide beta 1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan.
  Journal
J Biol Chem 277:47724-31 (2002)
DOI:10.1074/jbc.M205839200
  Sequence
[hsa:29071]

KEGG   ENZYME: 2.4.1.122
Entry
EC 2.4.1.122                Enzyme                                 

Name
N-acetylgalactosaminide beta-1,3-galactosyltransferase;
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase;
uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase;
UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase;
UDP-Gal:alpha-D-GalNAc-1,3-alpha-D-GalNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase;
wbnJ (gene name);
wbiP (gene name);
C1GALT1 (gene name);
UDP-alpha-D-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-galactose:N-acetyl-alpha-D-galactosaminyl-R beta-1,3-galactosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-alpha-D-galactose + N-acetyl-alpha-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R [RN:R05908]
Reaction(KEGG)
R05908(G);
(other) R10436
Substrate
UDP-alpha-D-galactose [CPD:C00052];
N-acetyl-alpha-D-galactosaminyl-R [CPD:C04387]
Product
UDP [CPD:C00015];
beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R [CPD:C04750]
Comment
The eukaryotic enzyme can act on non-reducing O-serine-linked N-acetylgalactosamine residues in mucin glycoproteins, forming the T-antigen. The bacterial enzyme, found in some pathogenic strains, is involved in biosynthesis of the O-antigen repeating unit.
History
EC 2.4.1.122 created 1984 (EC 2.4.1.307 created 2013, incorporated 2016), modified 2016
Pathway
ec00512  Mucin type O-glycan biosynthesis
ec00514  Other types of O-glycan biosynthesis
ec01100  Metabolic pathways
Orthology
K00731  glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase
K21366  O-antigen biosynthesis beta-1,3-galactosyltransferase
Genes
HSA: 56913(C1GALT1)
PTR: 472288(C1GALT1)
PPS: 100977740(C1GALT1)
GGO: 101145951(C1GALT1)
PON: 100452461(C1GALT1)
NLE: 100583301(C1GALT1)
MCC: 696870(C1GALT1)
MCF: 102137839(C1GALT1)
CSAB: 103226504(C1GALT1)
RRO: 104668754(C1GALT1)
RBB: 108543414(C1GALT1)
CJC: 100406487(C1GALT1)
SBQ: 101029936(C1GALT1)
MMU: 94192(C1galt1)
MCAL: 110296408(C1galt1)
MPAH: 110316313(C1galt1)
RNO: 65044(C1galt1)
MUN: 110554784(C1galt1)
CGE: 100761169(C1galt1)
NGI: 103751705(C1galt1)
HGL: 101704643(C1galt1)
CCAN: 109703122(C1galt1)
OCU: 100359047(C1GALT1)
TUP: 102479007(C1GALT1)
CFA: 482314(C1GALT1)
VVP: 112923919(C1GALT1)
AML: 100483848(C1GALT1)
UMR: 103658758(C1GALT1)
UAH: 113260469(C1GALT1)
ORO: 101378420(C1GALT1)
ELK: 111147376
FCA: 101096459(C1GALT1)
PTG: 102965358(C1GALT1)
PPAD: 109263732(C1GALT1)
AJU: 106970015(C1GALT1)
BTA: 539417(C1GALT1)
BOM: 102287025(C1GALT1)
BIU: 109558238(C1GALT1)
BBUB: 102406993(C1GALT1)
CHX: 102169248(C1GALT1)
OAS: 101120567(C1GALT1)
SSC: 100525767(C1GALT1)
CFR: 102514986(C1GALT1)
CDK: 105088713(C1GALT1)
BACU: 103001219(C1GALT1)
LVE: 103071088(C1GALT1)
OOR: 101282789(C1GALT1)
DLE: 111181388(C1GALT1)
PCAD: 102983236(C1GALT1)
ECB: 100063865(C1GALT1)
EPZ: 103540682(C1GALT1)
EAI: 106839569(C1GALT1)
MYB: 102244854(C1GALT1) 102250159
MYD: 102754234(C1GALT1)
MNA: 107541729(C1GALT1)
HAI: 109394810(C1GALT1)
DRO: 112319804(C1GALT1)
PALE: 102883390(C1GALT1)
RAY: 107504471(C1GALT1)
MJV: 108406054(C1GALT1)
LAV: 100670784(C1GALT1)
TMU: 101357588
SHR: 100932643(C1GALT1)
PCW: 110217609(C1GALT1)
OAA: 103169736(C1GALT1)
GGA: 420575(C1GALT1)
MGP: 100542429(C1GALT1)
CJO: 107309116(C1GALT1)
NMEL: 110394018(C1GALT1)
APLA: 101797632(C1GALT1)
ACYG: 106037532(C1GALT1)
TGU: 100221974(C1GALT1)
LSR: 110474721(C1GALT1)
SCAN: 103812837(C1GALT1)
GFR: 102032158(C1GALT1)
FAB: 101810221(C1GALT1)
PHI: 102103229(C1GALT1) 102104490
PMAJ: 107199204 107200786(C1GALT1)
CCAE: 111924251(C1GALT1) 111944042
CCW: 104689153(C1GALT1)
ETL: 114073121(C1GALT1)
FPG: 101923797(C1GALT1)
FCH: 102059381(C1GALT1)
CLV: 102088254(C1GALT1)
EGZ: 104129130(C1GALT1)
ACUN: 113476756(C1GALT1)
PADL: 103922365(C1GALT1)
AAM: 106483404(C1GALT1) 106492776
AMJ: 102558826(C1GALT1) 102575907
PSS: 102460792(C1GALT1)
CPIC: 101931210 101942937(C1GALT1) 101945118
ACS: 100554192 100562160(c1galt1)
PVT: 110070539 110073023(C1GALT1)
PBI: 103050549(C1GALT1) 103063573
PMUR: 107283657(C1GALT1) 107288525
TSR: 106539635 106540395(C1GALT1)
PMUA: 114586421 114607087(C1GALT1)
XLA: 108707741 108708597 108708598 108709868 108709869 108718847(c1galt1.L) 108719911(c1galt1.S) 444326(LOC100496837.L)
DRE: 337131(c1galt1b) 555344(si:dkey-202e17.1) 557675(c1galt1a)
IPU: 108272220(c1galt1b) 108276279
PHYP: 113530505 113532793(c1galt1) 113545818
PRET: 103465384 103467345 103471939(c1galt1)
AOCE: 111566642 111575167(c1galt1) 111587244
CSEM: 103385080 103385956 103394502(c1galt1)
SLAL: 111667825 111668780(c1galt1) 111668905
BPEC: 110161213(c1galt1) 110164964 110168386
SFM: 108918317 108935659(c1galt1)
RTP: 109910639(c1galt1) 109927325
CIN: 100182788
DME: Dmel_CG2975(CG2975) Dmel_CG2983(CG2983) Dmel_CG3119(CG3119) Dmel_CG34056(CG34056) Dmel_CG34057(CG34057) Dmel_CG34451(CG34451) Dmel_CG34452(CG34452) Dmel_CG7440(tgy) Dmel_CG8708(CG8708) Dmel_CG9520(C1GalTA)
DSI: Dsimw501_GD10181(Dsim_GD10181) Dsimw501_GD12540(Dsim_GD12540) Dsimw501_GD12541(Dsim_GD12541) Dsimw501_GD13582(Dsim_GD13582) Dsimw501_GD22375(Dsim_GD22375) Dsimw501_GD22798(Dsim_GD22798) Dsimw501_GD23186(Dsim_GD23186) Dsimw501_GD23187(Dsim_GD23187) Dsimw501_GD24465(Dsim_GD24465) Dsimw501_GD27301(Dsim_GD27301)
PGC: 109856374
NVI: 100120600
BMOR: 101746328
PMAC: 106709178
PRAP: 110993263
HAW: 110374915
TNL: 113498994
API: 100168660
DNX: 107167669
AGS: 114122443
RMD: 113549883
BTAB: 109042199
ZNE: 110837984
CEL: CELE_C38H2.2(C38H2.2)
CBR: CBG18398
TSP: Tsp_00464
ADF: 107348169
AMIL: 114954137
PDAM: 113668011
SPIS: 111340814
DGT: 114516537
SMIN: v1.2.011019.t1(symbB.v1.2.011019.t1)
NGD: NGA_0449900(C1GALT1)
ECG: E2348C_2172(wbiP)
 » show all
Reference
1  [PMID:6789880]
  Authors
Hesford FJ, Berger EG, Van den Eijnden DH.
  Title
Identification of the product formed by human erythrocyte galactosyltransferase.
  Journal
Biochim Biophys Acta 659:302-11 (1981)
DOI:10.1016/0005-2744(81)90056-5
Reference
2  [PMID:6801057]
  Authors
Mendicino J, Sivakami S, Davila M, Chandrasekaran EV.
  Title
Purification and properties of UDP-gal:N-acetylgalactosaminide mucin: beta 1,3-galactosyltransferase from swine trachea mucosa.
  Journal
J Biol Chem 257:3987-94 (1982)
Reference
3  [PMID:6366476]
  Authors
Schachter H, Narasimhan S, Gleeson P, Vella G.
  Title
Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type.
  Journal
Methods Enzymol 98:98-134 (1983)
DOI:10.1016/0076-6879(83)98143-0
Reference
4  [PMID:11677243]
  Authors
Ju T, Brewer K, D'Souza A, Cummings RD, Canfield WM
  Title
Cloning and expression of human core 1 beta1,3-galactosyltransferase.
  Journal
J Biol Chem 277:178-86 (2002)
DOI:10.1074/jbc.M109060200
  Sequence
[hsa:56913] [mmu:94192] [rno:65044] [cel:CELE_C38H2.2] [dme:Dmel_CG9520 Dmel_CG8708]
Reference
5  [PMID:18179256]
  Authors
Yi W, Perali RS, Eguchi H, Motari E, Woodward R, Wang PG
  Title
Characterization of a bacterial beta-1,3-galactosyltransferase with application in the synthesis of tumor-associated T-antigen mimics.
  Journal
Biochemistry 47:1241-8 (2008)
DOI:10.1021/bi7020712
Reference
6  [PMID:20418877]
  Authors
Woodward R, Yi W, Li L, Zhao G, Eguchi H, Sridhar PR, Guo H, Song JK, Motari E, Cai L, Kelleher P, Liu X, Han W, Zhang W, Ding Y, Li M, Wang PG
  Title
In vitro bacterial polysaccharide biosynthesis: defining the functions of Wzy and Wzz.
  Journal
Nat Chem Biol 6:418-23 (2010)
DOI:10.1038/nchembio.351
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.122
IUBMB Enzyme Nomenclature: 2.4.1.122
ExPASy - ENZYME nomenclature database: 2.4.1.122
BRENDA, the Enzyme Database: 2.4.1.122
CAS: 97089-61-7

KEGG   REACTION: R05908
Entry
R05908                      Reaction                               

Definition
UDP-D-galactose + Tn antigen <=> UDP + T antigen
Equation
Enzyme
Pathway
rn00512  Mucin type O-glycan biosynthesis
rn00514  Other types of O-glycan biosynthesis
rn01100  Metabolic pathways
Module
M00056  O-glycan biosynthesis, mucin type core
Orthology
K00731  glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]
K09653  C1GALT1-specific chaperone 1
Other DBs
RHEA: 56203

DBGET integrated database retrieval system