KEGG   ORTHOLOGY: K00744
Entry
K00744                      KO                                     

Name
MGAT5
Definition
alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]
Pathway
ko00510  N-Glycan biosynthesis
ko01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K00744  MGAT5; alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00744  MGAT5; alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.155  alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
     K00744  MGAT5; alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
Glycosyltransferases [BR:ko01003]
 Glycan extension
  N-Glycan
   K00744  MGAT5; alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
Other DBs
RN: R05991 R07622
GO: 0030144
CAZy: GT18
Genes
HSA: 4249(MGAT5)
PTR: 459625(MGAT5)
PPS: 100989629(MGAT5)
GGO: 101129003(MGAT5)
PON: 100445523(MGAT5)
NLE: 100597446(MGAT5)
MCC: 709108(MGAT5)
MCF: 102123398(MGAT5)
CSAB: 103216975(MGAT5)
RRO: 104654400(MGAT5)
RBB: 108539646(MGAT5)
CJC: 100414526(MGAT5)
SBQ: 101038866(MGAT5)
MMU: 107895(Mgat5)
MCAL: 110290015(Mgat5)
MPAH: 110321291(Mgat5)
RNO: 65271(Mgat5)
MUN: 110551079(Mgat5)
CGE: 100760162(Mgat5)
NGI: 103733594(Mgat5)
HGL: 101721991(Mgat5)
CCAN: 109689552 109689553
OCU: 100346879(MGAT5)
TUP: 102497975(MGAT5)
CFA: 483895(MGAT5)
VVP: 112932611(MGAT5)
AML: 100483104(MGAT5)
UMR: 103667662(MGAT5)
UAH: 113263431(MGAT5)
ORO: 101379628(MGAT5)
ELK: 111141394
FCA: 101088682(MGAT5)
PTG: 102969054(MGAT5)
PPAD: 109270081(MGAT5)
AJU: 106983003(MGAT5)
BTA: 537595(MGAT5)
BOM: 102275628(MGAT5)
BIU: 109568385(MGAT5)
BBUB: 102393516(MGAT5)
CHX: 102174983(MGAT5)
OAS: 101107672(MGAT5)
SSC: 100512563(MGAT5)
CFR: 102521418(MGAT5)
CDK: 105092441(MGAT5)
BACU: 102997655(MGAT5)
LVE: 103072240(MGAT5)
OOR: 101288542(MGAT5)
DLE: 111172696(MGAT5)
ECB: 100050356(MGAT5)
EPZ: 103555913(MGAT5)
EAI: 106836533(MGAT5)
MYB: 102246850(MGAT5)
MYD: 102761898(MGAT5)
MNA: 107531999(MGAT5)
HAI: 109374684(MGAT5)
DRO: 112313014(MGAT5)
PALE: 102884190(MGAT5)
RAY: 107520333(MGAT5)
MJV: 108395954 108406913
LAV: 100664057(MGAT5)
TMU: 101345363
MDO: 100011845(MGAT5)
SHR: 100929992(MGAT5)
PCW: 110223747(MGAT5)
OAA: 100091600(MGAT5)
GGA: 424286(MGAT5)
MGP: 100541307(MGAT5)
CJO: 107316876(MGAT5)
NMEL: 110399356(MGAT5)
APLA: 101797784(MGAT5)
ACYG: 106039337(MGAT5)
TGU: 100228988(MGAT5)
LSR: 110480631(MGAT5)
SCAN: 103814283(MGAT5)
GFR: 102042048(MGAT5)
FAB: 101814359(MGAT5)
PHI: 102101886(MGAT5)
PMAJ: 107207494(MGAT5)
CCAE: 111932311(MGAT5)
CCW: 104694065(MGAT5)
ETL: 114062071(MGAT5)
FPG: 101918414(MGAT5)
FCH: 102055854(MGAT5)
CLV: 102084918(MGAT5)
EGZ: 104129527(MGAT5)
NNI: 104009751(MGAT5)
ACUN: 113482013(MGAT5)
PADL: 103918490(MGAT5)
AAM: 106498453(MGAT5)
ASN: 102386992(MGAT5)
AMJ: 102563315(MGAT5)
PSS: 102455461(MGAT5)
CMY: 102946323(MGAT5)
CPIC: 101938965(MGAT5)
ACS: 100566008(mgat5)
PVT: 110071860(MGAT5)
PBI: 103063095(MGAT5) 103064781
PMUR: 107284397(MGAT5)
TSR: 106545857(MGAT5)
PMUA: 114604540(MGAT5)
GJA: 107108668(MGAT5) 107111387
XLA: 108701278 108702251
XTR: 100145551(mgat5)
NPR: 108792298(MGAT5)
DRE: 724006(mgat5)
SRX: 107739338 107745986
SANH: 107653587 107663499
SGH: 107586987 107593035(mgat5)
CCAR: 109047295 109083375 109087669
IPU: 108259240(mgat5)
PHYP: 113547435(mgat5)
AMEX: 103037113(mgat5)
EEE: 113581466(mgat5)
TRU: 101072031(mgat5) 101074995
TNG: GSTEN00006450G001 GSTEN00013473G001
LCO: 104925340(mgat5)
NCC: 104941679(mgat5) 104962910
MZE: 101481161(mgat5)
ONL: 100691248(mgat5)
OLA: 101168186(mgat5)
XMA: 102232481(mgat5) 102236488
XCO: 114140432(mgat5) 114148135
PRET: 103460330 103476254(mgat5)
CVG: 107094135 107094137(mgat5)
NFU: 107381041 107390173(mgat5)
KMR: 108238485 108246486(mgat5)
ALIM: 106519126 106519129 106529442
AOCE: 111562783 111582951
CSEM: 103389683(mgat5)
POV: 109631205 109639749(mgat5)
LCF: 108887100 108891873
SDU: 111218827 111222699(mgat5)
SLAL: 111646016(mgat5) 111667400
HCQ: 109514989(mgat5)
BPEC: 110153275(mgat5)
MALB: 109955689(mgat5) 109968552
SASA: 106574313 106575089
OTW: 112253925 112253994 112266585
SALP: 111953416 111971109
ELS: 105019667(mgat5)
SFM: 108929747 108941965(mgat5)
PKI: 111849087(mgat5) 111849468
LCM: 102363158(MGAT5)
CMK: 103180379(mgat5) 103184928(ccdc126)
RTP: 109917938 109920420 109923773
BFO: 118405638
CIN: 100175898 108949978
SPU: 100888694
APLC: 110989436
SKO: 100366560
CEL: CELE_C55B7.2(gly-2)
CBR: CBG12645(Cbr-gly-2)
BMY: Bm1_56690
NAI: NECAME_14592
TSP: Tsp_11593
HRO: HELRODRAFT_115589 HELRODRAFT_180890
LGI: LOTGIDRAFT_172419
PCAN: 112565538
CRG: 105330629
MYI: 110458649
OBI: 106880226
LAK: 106160238 106160396 106171734 106172929 106177233 106181457
SMM: Smp_040510 Smp_144260
SHX: MS3_04856
OVI: T265_04472
NVE: 5509104 5517864 5517897 5517929 5521677
EPA: 110232340 110232355 110232390 110241019 110241101 110244956
ADF: 107327239 107337307 107345019 107345720 107345743 107347453 107353933
AMIL: 114954488 114954490 114957136 114961709
PDAM: 113671483 113678068 113683774 113683775 113683780
SPIS: 111327556 111327561 111332554 111336901
DGT: 114517678 114520371 114522055 114527192
HMG: 100200937 100214696
 » show all
Reference
  Authors
Warren CE, Krizus A, Roy PJ, Culotti JG, Dennis JW
  Title
The Caenorhabditis elegans gene, gly-2, can rescue the N-acetylglucosaminyltransferase V mutation of Lec4 cells.
  Journal
J Biol Chem 277:22829-38 (2002)
DOI:10.1074/jbc.M201390200
  Sequence

  All links  
Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   CAZY (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Gene (956)   
   KEGG GENES (246)   
   KEGG MGENES (228)   
   RefGene (478)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (970)   

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KEGG   ORTHOLOGY: K09661
Entry
K09661                      KO                                     

Name
MGAT5B
Definition
mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]
Pathway
ko00510  N-Glycan biosynthesis
ko00515  Mannose type O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
   00515 Mannose type O-glycan biosynthesis
    K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-  
     K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Glycosyltransferases [BR:ko01003]
 Glycan extension
  Wide specificity
   K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Other DBs
RN: R05991 R07621 R07622 R07623 R07624 R07625
CAZy: GT18
Genes
HSA: 146664(MGAT5B)
PTR: 740411(MGAT5B)
PPS: 100988030(MGAT5B)
GGO: 101135753 115933466
PON: 103892903(MGAT5B)
NLE: 100583905(MGAT5B)
MCC: 708299(MGAT5B)
MCF: 102137306(MGAT5B)
CSAB: 103242981(MGAT5B)
RRO: 104681258(MGAT5B)
RBB: 108537447(MGAT5B)
CJC: 100411284(MGAT5B)
SBQ: 101050351(MGAT5B)
MMU: 268510(Mgat5b)
MCAL: 110304585(Mgat5b)
MPAH: 110331691(Mgat5b)
RNO: 303693(Mgat5b)
MUN: 110550545(Mgat5b)
CGE: 100771275(Mgat5b)
NGI: 103730646(Mgat5b)
HGL: 101721905(Mgat5b)
CCAN: 109685591(Mgat5b)
OCU: 103346454
TUP: 102498034(MGAT5B)
CFA: 483337(MGAT5B)
VVP: 112920839(MGAT5B)
AML: 100474282(MGAT5B)
UMR: 103665955(MGAT5B)
UAH: 113244582(MGAT5B)
ORO: 101370759(MGAT5B)
ELK: 111160316
FCA: 101087025(MGAT5B)
PTG: 102968409(MGAT5B)
PPAD: 109276880(MGAT5B)
AJU: 106988358(MGAT5B)
BTA: 785213(MGAT5B)
BOM: 102283069(MGAT5B)
BIU: 109574536(MGAT5B)
BBUB: 102392676(MGAT5B)
CHX: 102189620(MGAT5B)
OAS: 101115810(MGAT5B)
SSC: 100516218(MGAT5B)
CFR: 102515392(MGAT5B)
CDK: 105092171(MGAT5B)
BACU: 103007096(MGAT5B)
LVE: 103090911(MGAT5B)
OOR: 101282242(MGAT5B)
DLE: 111182774(MGAT5B)
PCAD: 102983477(MGAT5B)
ECB: 100058438(MGAT5B)
EPZ: 103557464(MGAT5B)
EAI: 106830345(MGAT5B)
MYB: 102255570(MGAT5B)
MYD: 102764507(MGAT5B)
MNA: 107536590(MGAT5B)
HAI: 109383762(MGAT5B)
DRO: 112298821(MGAT5B)
PALE: 102890069(MGAT5B)
RAY: 107510048(MGAT5B)
MJV: 108391124
LAV: 100672358(MGAT5B)
TMU: 101351581
MDO: 100027070(MGAT5B)
SHR: 100920566(MGAT5B)
PCW: 110193942(MGAT5B)
OAA: 100076017(MGAT5B)
GGA: 427801(MGAT5B)
MGP: 100538548(MGAT5B)
CJO: 107322123(MGAT5B)
NMEL: 110407368(MGAT5B)
APLA: 101789960(MGAT5B)
ACYG: 106034817(MGAT5B)
TGU: 100226604(MGAT5B)
LSR: 110479607(MGAT5B)
SCAN: 103820008(MGAT5B)
GFR: 102043857(MGAT5B)
FAB: 101814820(MGAT5B)
PHI: 102109000(MGAT5B)
PMAJ: 107212588(MGAT5B)
CCAE: 111937261(MGAT5B)
CCW: 104694398(MGAT5B)
ETL: 114058596(MGAT5B)
FPG: 101919407(MGAT5B)
FCH: 102048178(MGAT5B)
CLV: 102095388(MGAT5B)
EGZ: 104125302(MGAT5B)
NNI: 104022866(MGAT5B)
ACUN: 113486784(MGAT5B)
PADL: 103919074(MGAT5B)
AAM: 106489150(MGAT5B)
ASN: 102388497(MGAT5B)
AMJ: 102576237(MGAT5B)
PSS: 102454679(MGAT5B)
CMY: 102937846(MGAT5B)
CPIC: 101931772(MGAT5B)
ACS: 100558987(mgat5b)
PVT: 110085908(MGAT5B)
PBI: 103057281(MGAT5B)
PMUR: 107291755(MGAT5B)
TSR: 106543272(MGAT5B)
PMUA: 114590668(MGAT5B)
GJA: 107113485(MGAT5B)
XLA: 108701139(mgat5b.L) 108702220(mgat5b.S)
XTR: 100487001(mgat5b)
NPR: 108786412(MGAT5B)
DRE: 101884072(mgat5b)
SRX: 107731677 107743022
SANH: 107684593(mgat5b)
SGH: 107562046
CCAR: 109054006 109069092
IPU: 108272407 108274344
PHYP: 113528345 113538230
AMEX: 103031728
EEE: 113571430 113587790(mgat5b)
TRU: 101072839(mgat5b) 115253357
TNG: GSTEN00021837G001
LCO: 104925611 104926545
NCC: 104955866(mgat5b)
MZE: 101479752 101480711
ONL: 100696723 100708112
OLA: 101163172 101173907(mgat5b)
XMA: 102226673 102232182
XCO: 114145485 114160416
PRET: 103467751 103469134
CVG: 107089388
NFU: 107376702(mgat5b) 107382438
KMR: 108242732 108242934
ALIM: 106515282 106516503
AOCE: 111564240 111565363
CSEM: 103383590 103393196(mgat5b)
POV: 109627726 109639533
LCF: 108875950 108881055
SDU: 111230274 111236335
SLAL: 111647501 111659738
HCQ: 109514891
BPEC: 110172581
MALB: 109958853 109966254
SASA: 106564922 106588199 106601405 106607001
OTW: 112237970 112245787 112264697
SALP: 112069103
ELS: 105012891 105021617
SFM: 108939929(mgat5b)
PKI: 111847779(mgat5b)
LCM: 102345205(MGAT5B)
CMK: 103175452(mgat5b)
RTP: 109911752
 » show all
Reference
  Authors
Inamori K, Endo T, Ide Y, Fujii S, Gu J, Honke K, Taniguchi N
  Title
Molecular cloning and characterization of human GnT-IX, a novel beta1,6-N-acetylglucosaminyltransferase that is specifically expressed in the brain.
  Journal
J Biol Chem 278:43102-9 (2003)
DOI:10.1074/jbc.M308255200
  Sequence
[hsa:146664]

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   CAZY (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (6)   
   KEGG REACTION (6)   
Gene (736)   
   KEGG GENES (177)   
   KEGG MGENES (217)   
   RefGene (339)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (754)   

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KEGG   ENZYME: 2.4.1.155
Entry
EC 2.4.1.155                Enzyme                                 

Name
alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase;
MGAT5 (gene name);
N-acetylglucosaminyltransferase V;
alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase;
UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase;
alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase;
GnTV;
GlcNAc-T V;
UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-alpha-D-glucosamine:N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)-beta-D-mannosyl-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] = UDP + beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] [RN:R05991]
Reaction(KEGG)
R05991(G);
(other) R04665
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
Product
UDP [CPD:C00015];
beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
Comment
Requires Mg2+. The enzyme, found in vertebrates, participates in the processing of N-glycans in the Golgi apparatus. It catalyses the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides, and thus enables the synthesis of tri- and tetra-antennary complexes.
History
EC 2.4.1.155 created 1986, modified 2001, modified 2018
Pathway
ec00510  N-Glycan biosynthesis
ec01100  Metabolic pathways
Orthology
K00744  alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
Genes
HSA: 4249(MGAT5)
PTR: 459625(MGAT5)
PPS: 100989629(MGAT5)
GGO: 101129003(MGAT5)
PON: 100445523(MGAT5)
NLE: 100597446(MGAT5)
MCC: 709108(MGAT5)
MCF: 102123398(MGAT5)
CSAB: 103216975(MGAT5)
RRO: 104654400(MGAT5)
RBB: 108539646(MGAT5)
CJC: 100414526(MGAT5)
SBQ: 101038866(MGAT5)
MMU: 107895(Mgat5)
MCAL: 110290015(Mgat5)
MPAH: 110321291(Mgat5)
RNO: 65271(Mgat5)
MUN: 110551079(Mgat5)
CGE: 100760162(Mgat5)
NGI: 103733594(Mgat5)
HGL: 101721991(Mgat5)
CCAN: 109689552 109689553
OCU: 100346879(MGAT5)
TUP: 102497975(MGAT5)
CFA: 483895(MGAT5)
VVP: 112932611(MGAT5)
AML: 100483104(MGAT5)
UMR: 103667662(MGAT5)
UAH: 113263431(MGAT5)
ORO: 101379628(MGAT5)
ELK: 111141394
FCA: 101088682(MGAT5)
PTG: 102969054(MGAT5)
PPAD: 109270081(MGAT5)
AJU: 106983003(MGAT5)
BTA: 537595(MGAT5)
BOM: 102275628(MGAT5)
BIU: 109568385(MGAT5)
BBUB: 102393516(MGAT5)
CHX: 102174983(MGAT5)
OAS: 101107672(MGAT5)
SSC: 100512563(MGAT5)
CFR: 102521418(MGAT5)
CDK: 105092441(MGAT5)
BACU: 102997655(MGAT5)
LVE: 103072240(MGAT5)
OOR: 101288542(MGAT5)
DLE: 111172696(MGAT5)
ECB: 100050356(MGAT5)
EPZ: 103555913(MGAT5)
EAI: 106836533(MGAT5)
MYB: 102246850(MGAT5)
MYD: 102761898(MGAT5)
MNA: 107531999(MGAT5)
HAI: 109374684(MGAT5)
DRO: 112313014(MGAT5)
PALE: 102884190(MGAT5)
RAY: 107520333(MGAT5)
MJV: 108395954 108406913
LAV: 100664057(MGAT5)
TMU: 101345363
MDO: 100011845(MGAT5)
SHR: 100929992(MGAT5)
PCW: 110223747(MGAT5)
OAA: 100091600(MGAT5)
GGA: 424286(MGAT5)
MGP: 100541307(MGAT5)
CJO: 107316876(MGAT5)
NMEL: 110399356(MGAT5)
APLA: 101797784(MGAT5)
ACYG: 106039337(MGAT5)
TGU: 100228988(MGAT5)
LSR: 110480631(MGAT5)
SCAN: 103814283(MGAT5)
GFR: 102042048(MGAT5)
FAB: 101814359(MGAT5)
PHI: 102101886(MGAT5)
PMAJ: 107207494(MGAT5)
CCAE: 111932311(MGAT5)
CCW: 104694065(MGAT5)
ETL: 114062071(MGAT5)
FPG: 101918414(MGAT5)
FCH: 102055854(MGAT5)
CLV: 102084918(MGAT5)
EGZ: 104129527(MGAT5)
NNI: 104009751(MGAT5)
ACUN: 113482013(MGAT5)
PADL: 103918490(MGAT5)
AAM: 106498453(MGAT5)
ASN: 102386992(MGAT5)
AMJ: 102563315(MGAT5)
PSS: 102455461(MGAT5)
CMY: 102946323(MGAT5)
CPIC: 101938965(MGAT5)
ACS: 100566008(mgat5)
PVT: 110071860(MGAT5)
PBI: 103063095(MGAT5) 103064781
PMUR: 107284397(MGAT5)
TSR: 106545857(MGAT5)
PMUA: 114604540(MGAT5)
GJA: 107108668(MGAT5) 107111387
XLA: 108701278 108702251
XTR: 100145551(mgat5)
NPR: 108792298(MGAT5)
DRE: 724006(mgat5)
SRX: 107739338 107745986
SANH: 107653587 107663499
SGH: 107586987 107593035(mgat5)
CCAR: 109047295 109083375 109087669
IPU: 108259240(mgat5)
PHYP: 113547435(mgat5)
AMEX: 103037113(mgat5)
EEE: 113581466(mgat5)
TRU: 101072031(mgat5) 101074995
TNG: GSTEN00006450G001 GSTEN00013473G001
LCO: 104925340(mgat5)
NCC: 104941679(mgat5) 104962910
MZE: 101481161(mgat5)
ONL: 100691248(mgat5)
OLA: 101168186(mgat5)
XMA: 102232481(mgat5) 102236488
XCO: 114140432(mgat5) 114148135
PRET: 103460330 103476254(mgat5)
CVG: 107094135 107094137(mgat5)
NFU: 107381041 107390173(mgat5)
KMR: 108238485 108246486(mgat5)
ALIM: 106519126 106519129 106529442
AOCE: 111562783 111582951
CSEM: 103389683(mgat5)
POV: 109631205 109639749(mgat5)
LCF: 108887100 108891873
SDU: 111218827 111222699(mgat5)
SLAL: 111646016(mgat5) 111667400
HCQ: 109514989(mgat5)
BPEC: 110153275(mgat5)
MALB: 109955689(mgat5) 109968552
SASA: 106574313 106575089
OTW: 112253925 112253994 112266585
SALP: 111953416 111971109
ELS: 105019667(mgat5)
SFM: 108929747 108941965(mgat5)
PKI: 111849087(mgat5) 111849468
LCM: 102363158(MGAT5)
CMK: 103180379(mgat5) 103184928(ccdc126)
RTP: 109917938 109920420 109923773
BFO: 118405638
CIN: 100175898 108949978
SPU: 100888694
APLC: 110989436
SKO: 100366560
CEL: CELE_C55B7.2(gly-2)
CBR: CBG12645(Cbr-gly-2)
BMY: Bm1_56690
NAI: NECAME_14592
TSP: Tsp_11593
HRO: HELRODRAFT_115589 HELRODRAFT_180890
LGI: LOTGIDRAFT_172419
PCAN: 112565538
CRG: 105330629
MYI: 110458649
OBI: 106880226
LAK: 106160238 106160396 106171734 106172929 106177233 106181457
SMM: Smp_040510 Smp_144260
SHX: MS3_04856
OVI: T265_04472
NVE: 5509104 5517864 5517897 5517929 5521677
EPA: 110232340 110232355 110232390 110241019 110241101 110244956
ADF: 107327239 107337307 107345019 107345720 107345743 107347453 107353933
AMIL: 114954488 114954490 114957136 114961709
PDAM: 113671483 113678068 113683774 113683775 113683780
SPIS: 111327556 111327561 111332554 111336901
DGT: 114517678 114520371 114522055 114527192
HMG: 100200937 100214696
 » show all
Reference
1  [PMID:6216250]
  Authors
Cummings RD, Trowbridge IS, Kornfeld S.
  Title
A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc: alpha-D-mannoside beta 1,6 N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 257:13421-7 (1982)
Reference
2  [PMID:2834054]
  Authors
Hindsgaul O, Tahir SH, Srivastava OP, Pierce M.
  Title
The trisaccharide beta-D-GlcpNAc-(1----2)-alpha-D-Manp-(1----6)-beta-D-Manp, as its 8-methoxycarbonyloctyl glycoside, is an acceptor selective for N-acetylglucosaminyltransferase V.
  Journal
Carbohydr Res 173:263-72 (1988)
DOI:10.1016/S0008-6215(00)90822-X
Reference
3  [PMID:1531335]
  Authors
Shoreibah MG, Hindsgaul O, Pierce M
  Title
Purification and characterization of rat kidney UDP-N-acetylglucosamine: alpha-6-D-mannoside beta-1,6-N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 267:2920-7 (1992)
Reference
4  [PMID:8393437]
  Authors
Gu J, Nishikawa A, Tsuruoka N, Ohno M, Yamaguchi N, Kangawa K, Taniguchi N
  Title
Purification and characterization of UDP-N-acetylglucosamine: alpha-6-D-mannoside beta 1-6N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase V) from  a human lung cancer cell line.
  Journal
J Biochem 113:614-9 (1993)
DOI:10.1093/oxfordjournals.jbchem.a124091
Reference
5  [PMID:10395745]
  Authors
Park C, Jin UH, Lee YC, Cho TJ, Kim CH
  Title
Characterization of UDP-N-acetylglucosamine:alpha-6-d-mannoside beta-1,6-N-acetylglucosaminyltransferase V from a human hepatoma cell line Hep3B.
  Journal
Arch Biochem Biophys 367:281-8 (1999)
DOI:10.1006/abbi.1999.1252
  Sequence
[hsa:4249]
Reference
6  [PMID:11872751]
  Authors
Saito T, Miyoshi E, Sasai K, Nakano N, Eguchi H, Honke K, Taniguchi N
  Title
A secreted type of beta 1,6-N-acetylglucosaminyltransferase V (GnT-V) induces tumor angiogenesis without mediation of glycosylation: a novel function of GnT-V  distinct from the original glycosyltransferase activity.
  Journal
J Biol Chem 277:17002-8 (2002)
DOI:10.1074/jbc.M200521200
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.155
IUBMB Enzyme Nomenclature: 2.4.1.155
ExPASy - ENZYME nomenclature database: 2.4.1.155
BRENDA, the Enzyme Database: 2.4.1.155
CAS: 83588-90-3

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Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (4)   
   KEGG GLYCAN (4)   
Chemical reaction (4)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (953)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (246)   
   KEGG MGENES (228)   
   RefGene (478)   
Protein sequence (2101)   
   UniProt (2076)   
   SWISS-PROT (7)   
   RefSeq(pep) (15)   
   PDBSTR (3)   
DNA sequence (28)   
   RefSeq(nuc) (17)   
   GenBank (6)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   InterPro (2)   
All databases (3103)   

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KEGG   REACTION: R05991
Entry
R05991                      Reaction                               

Definition
UDP-N-acetyl-D-glucosamine + G00020 <=> UDP + G00021
Equation
Enzyme
Pathway
rn00510  N-Glycan biosynthesis
rn01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Orthology
K00744  alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]
K09661  mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]
Other DBs
RHEA: 56091

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG GLYCAN (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (425)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (423)   
All databases (437)   

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