KEGG ORTHOLOGY: K01165

ORTHOLOGY: K01165

Entry

K01165                      KO

Symbol

RNASEL

Name

ribonuclease L

Pathway

map04621

NOD-like receptor signaling pathway

map05160

Hepatitis C

map05164

Influenza A

map05168

Herpes simplex virus 1 infection

Disease

H02530

Hereditary prostate cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K01165  RNASEL; ribonuclease L
09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K01165  RNASEL; ribonuclease L
   05164 Influenza A
    K01165  RNASEL; ribonuclease L
   05168 Herpes simplex virus 1 infection
    K01165  RNASEL; ribonuclease L

Genes

HSA:	6041(RNASEL)

PTR:	469607(RNASEL)

PPS:	100977181(RNASEL)

GGO:	101124891(RNASEL)

PON:	100174437(RNASEL)

PPYG:

129041977(RNASEL)

NLE:	100604656(RNASEL)

HMH:	116457570(RNASEL)

SSYN:

129458480(RNASEL)

MCC:	715647(RNASEL)

MCF:	102143958(RNASEL)

MTHB:

126940643

MNI:	105484553(RNASEL)

CSAB:

103230468(RNASEL)

CATY:

105580392(RNASEL)

PANU:

101012661(RNASEL)

TGE:	112631975(RNASEL)

MLEU:

105550414(RNASEL)

RRO:	104666789(RNASEL)

RBB:	108512746(RNASEL)

TFN:	117074768(RNASEL)

PTEH:

111536958(RNASEL)

CANG:

105511900(RNASEL)

CJC:	100405212(RNASEL)

SBQ:	101039040(RNASEL)

CIMI:

108301342(RNASEL)

ANAN:

105711803(RNASEL)

CSYR:

103276958(RNASEL)

MMUR:

105854989(RNASEL)

LCAT:

123626913(RNASEL)

PCOQ:

105806767(RNASEL)

OGA:	100961822(RNASEL)

MMU:	24014(Rnasel)

MCAL:

110299705(Rnasel)

MPAH:

110321873(Rnasel)

RNO:	359726(Rnasel)

MCOC:

116101429(Rnasel)

ANU:	117716320(Rnasel)

MUN:	110546181(Rnasel)

CGE:	100763013(Rnasel)

MAUA:

101825053(Rnasel)

PROB:

127223421(Rnasel)

MORG:

121455139 121455273

MFOT:

126497364

AAMP:

119827862 119827863

NGI:	103738491(Rnasel)

HGL:	101723907(Rnasel)

CPOC:

100192397(Rnasel)

CCAN:

109679313(Rnasel)

DORD:

105985004(Rnasel)

DSP:	122103844(Rnasel)

PLOP:

125359656(Rnasel)

NCAR:

124961813

MMMA:

107147318(Rnasel)

OCU:

100343787

OPI:	101524605(RNASEL)

TUP:	102494136(RNASEL)

GVR:	103600200(RNASEL)

CFA:	490310(RNASEL)

CLUD:

112648464(RNASEL)

VVP:	112921799(RNASEL)

VLG:	121499129(RNASEL)

NPO:	129505978(RNASEL)

AML:	100469504(RNASEL)

UMR:	103672422(RNASEL)

UAH:	113262726(RNASEL)

UAR:	123801383(RNASEL)

ELK:

111150728

LLV:

125085907

MPUF:

101680642(RNASEL)

MNP:	132025442(RNASEL)

MLK:	131814592(RNASEL)

NVS:	122918600(RNASEL)

ORO:	101366276(RNASEL)

EJU:	114222877(RNASEL)

ZCA:	113933373(RNASEL)

MLX:	118014362(RNASEL)

NSU:	110574199(RNASEL)

LWW:	102728083(RNASEL)

FCA:	101101102(RNASEL)

PYU:	121011815(RNASEL)

PCOO:

112857855(RNASEL)

PBG:	122476591(RNASEL)

PVIV:

125155730(RNASEL)

LRUF:

124510142

PTG:	102963811(RNASEL)

PPAD:

109254076(RNASEL)

PUC:

125925247

AJU:

106966736

HHV:	120245847(RNASEL)

BTA:	100048947(RNASEL)

BOM:	102269338(RNASEL)

BIU:	109570705(RNASEL)

BBUB:

102416386(RNASEL)

BBIS:

104998092(RNASEL)

CHX:	102191823(RNASEL)

OAS:	101103495(RNASEL)

BTAX:

128061820(RNASEL)

ODA:	120880484(RNASEL)

CCAD:

122452244(RNASEL)

MBEZ:

129551309(RNASEL)

SSC:	100048946(RNASEL)

CFR:	102512334(RNASEL)

CBAI:

105068943(RNASEL)

CDK:	105096236(RNASEL)

VPC:	102524962(RNASEL)

BACU:

103002285(RNASEL)

BMUS:

118885519(RNASEL)

LVE:	103087881(RNASEL)

OOR:	101286130(RNASEL)

DLE:	111184628(RNASEL)

PCAD:

102982973(RNASEL)

PSIU:

116760295(RNASEL)

NASI:

112391174(RNASEL)

ECB:	100048950(RNASEL)

EPZ:	103551879(RNASEL)

EAI:	106847453(RNASEL)

MYB:	102257262(RNASEL)

MYD:	102754018(RNASEL)

MMYO:

118673060(RNASEL)

MLF:	102435418(RNASEL)

MDT:	132220898(RNASEL)

PKL:	118721312(RNASEL)

EFUS:

103290117(RNASEL)

MNA:	107546295(RNASEL)

DRO:	112296814(RNASEL)

SHON:

118979149(RNASEL)

AJM:	119049606(RNASEL)

PDIC:

114512128(RNASEL)

PHAS:

123818537(RNASEL)

MMF:	118637844(RNASEL)

PPAM:

129081878(RNASEL)

HAI:	109379163(RNASEL)

RFQ:	117015254(RNASEL)

PALE:

102894053(RNASEL)

PGIG:

120617587(RNASEL)

PVP:	105292873(RNASEL)

RAY:	107511282(RNASEL)

MJV:	108390019(RNASEL)

TOD:	119241205(RNASEL)

SARA:

101549296(RNASEL)

SETR:

126013383(RNASEL)

LAV:	100662757(RNASEL)

TMU:

101358385

ETF:	101662447(RNASEL)

DNM:	101411252(RNASEL)

MDO:	100023689(RNASEL)

GAS:	123244356(RNASEL)

SHR:	116419074(RNASEL)

AFZ:

127562824

PCW:	110206836(RNASEL)

TVP:	118848773(RNASEL)

OAA:	100085631(RNASEL)

GGA:	424410(RNASEL)

PCOC:

116230459(RNASEL)

MGP:	100547585(RNASEL)

CJO:	107317269(RNASEL)

TPAI:

128072462(RNASEL)

LMUT:

125693451(RNASEL)

NMEL:

110402536(RNASEL)

APLA:

101800595(RNASEL)

ACYG:

106047798(RNASEL)

CATA:

118243274(RNASEL)

AFUL:

116492212(RNASEL)

SCAN:

103823366(RNASEL)

PMOA:

120512243(RNASEL)

OTC:	121344297(RNASEL)

PRUF:

121359807(RNASEL)

GFR:	102040751(RNASEL)

FAB:	101812172(RNASEL)

OMA:	130256510(RNASEL)

PHI:	102109495(RNASEL)

PMAJ:

107208483(RNASEL)

CCAE:

111932624(RNASEL)

CCW:	104695477(RNASEL)

CBRC:

103612699(RNASEL)

ZAB:	102062612(RNASEL)

ZLE:	135451176(RNASEL)

ACHL:

103805685(RNASEL)

SVG:	106852306(RNASEL)

MMEA:

130583584(RNASEL)

HRT:	120756723(RNASEL)

SATI:

136364738(RNASEL)

FPG:	101918377(RNASEL)

FCH:	102058883(RNASEL)

CCRI:

104164376(RNASEL)

NNT:	104413072(RNASEL)

SHAB:

115611871(RNASEL)

ACUN:

113482612(RNASEL)

TALA:

104361868(RNASEL)

ACHC:

115348753(RNASEL)

HALD:

104314165(RNASEL)

HLE:	104839977(RNASEL)

AGEN:

126041549

GCL:

127019297

CSTI:

104556489(RNASEL)

LDI:	104344942(RNASEL)

MNB:	103770057(RNASEL)

DPUB:

104301598(RNASEL)

AVIT:

104279474(RNASEL)

BRHI:

104492562(RNASEL)

EGZ:	104132048(RNASEL)

NNI:	104010377(RNASEL)

PCRI:

104038560(RNASEL)

PCAO:

104041831(RNASEL)

PADL:

103914022(RNASEL)

AFOR:

103896110(RNASEL)

FGA:	104079201(RNASEL)

GSTE:

104262568(RNASEL)

CLV:	102084643(RNASEL)

MUI:	104547612(RNASEL)

PGUU:

104465002(RNASEL)

PLET:

104618130(RNASEL)

EHS:	104514079(RNASEL)

CMAC:

104478660(RNASEL)

CUCA:

104058144(RNASEL)

TEO:	104375054(RNASEL)

BREG:

104635656(RNASEL)

OHA:	104333706(RNASEL)

ACAR:

104522339(RNASEL)

CPEA:

104386093(RNASEL)

CVF:	104293338(RNASEL)

RTD:	128913777(RNASEL)

AAM:	106494077(RNASEL)

AROW:

112975073(RNASEL)

NPD:	112950418(RNASEL)

TGT:	104581078(RNASEL)

DNE:	112983748(RNASEL)

SCAM:

104142669(RNASEL)

ASN:	102387444(RNASEL)

AMJ:	102570105(RNASEL)

PSS:	102443675(RNASEL) 102452402

CMY:	102941408 102944966

CCAY:

125641356

DCC:	119859748 122455371

CPIC:

103305975

TST:	117881608 117881728

CABI:

116818489 116818490

MRV:	120370121 120370122(RNASEL)

ACS:	100553088(rnasel)

ASAO:

132774392(RNASEL)

PVT:	110077052(RNASEL)

SUND:

121928772 121928906

PBI:	103060542(RNASEL)

PMUR:

107284990(RNASEL)

CTIG:

120305370(RNASEL)

TSR:	106541233(RNASEL)

PGUT:

117661130(RNASEL)

APRI:

131196227(RNASEL)

PTEX:

113438074(RNASEL)

NSS:	113413171(RNASEL)

VKO:	123027844(RNASEL) 123027845

PMUA:

114598514(RNASEL)

PRAF:

128415207(RNASEL)

ZVI:	118088358(RNASEL)

HCG:	128323170 128323171 128323175 128323176 128324293 128325189(RNASEL) 128353043

GJA:	107121033(RNASEL)

STOW:

125425022(RNASEL)

EMC:	129331346(RNASEL)

MUO:	115472721(RNASEL)

GSH:	117346504(RNASEL)

LCM:

CMK:

RTP:

CPLA:

HOC:

LERI:

PTRU:

DGT:

XEN:

Reference

PMID:11585831

Authors

Le Roy F, Bisbal C, Silhol M, Martinand C, Lebleu B, Salehzada T

Title

The 2-5A/RNase L/RNase L inhibitor (RLI) [correction of (RNI)] pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells.

Journal

J Biol Chem 276:48473-82 (2001)
DOI:10.1074/jbc.M107482200

Reference

PMID:7680958

Authors

Zhou A, Hassel BA, Silverman RH

Title

Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action.

Journal

Cell 72:753-65 (1993)
DOI:10.1016/0092-8674(93)90403-D

Sequence

[hsa:6041]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (343)   
   KEGG GENES (286)   
   KEGG MGENES (18)   
   RefGene (38)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (355)   

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