KEGG   ORTHOLOGY: K01330
Entry
K01330                      KO                                     

Name
C1R
Definition
complement component 1, r subcomponent [EC:3.4.21.41]
Pathway
ko04145  Phagosome
ko04610  Complement and coagulation cascades
ko05133  Pertussis
ko05150  Staphylococcus aureus infection
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H02240  Ehlers-Danlos syndrome periodontal type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K01330  C1R; complement component 1, r subcomponent
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01330  C1R; complement component 1, r subcomponent
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K01330  C1R; complement component 1, r subcomponent
  09171 Infectious disease: bacterial
   05133 Pertussis
    K01330  C1R; complement component 1, r subcomponent
   05150 Staphylococcus aureus infection
    K01330  C1R; complement component 1, r subcomponent
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01330  C1R; complement component 1, r subcomponent
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K01330  C1R; complement component 1, r subcomponent
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.41  complement subcomponent C_overbar_1r_
     K01330  C1R; complement component 1, r subcomponent
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01330  C1R; complement component 1, r subcomponent
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K01330  C1R; complement component 1, r subcomponent
Genes
HSA: 715(C1R)
PTR: 466939(C1R)
PPS: 100991297(C1R)
GGO: 101148245(C1R)
PON: 100173855(C1R) 112135770
NLE: 100591142(C1R)
MCC: 722133 722144
MCF: 101866354(C1R) 102135038
CSAB: 103218858(C1R)
RRO: 104681686
RBB: 108542014(C1R)
CJC: 100386784(C1R)
SBQ: 101033061(C1R)
MMU: 50909(C1ra) 667277(C1rb)
MPAH: 110314999 110316472(C1r)
RNO: 312705(C1r)
MUN: 110548593(C1r)
CGE: 100768476(C1r)
NGI: 103727485(C1r)
HGL: 101717538(C1r)
CCAN: 109682779(C1r)
OCU: 100342793(C1R)
TUP: 102496021(C1R)
CFA: 477707(C1R)
VVP: 112917317(C1R)
AML: 100472269(C1R)
UMR: 103656175(C1R)
UAH: 113257944(C1R)
ORO: 101377329(C1R)
ELK: 111159719
FCA: 101088940 111561323(C1R)
PTG: 102972961(C1R)
PPAD: 109276088(C1R)
AJU: 106965334(C1R)
BTA: 511581(C1R)
CHX: 102188569 102188835(C1R)
OAS: 101107430(C1R)
SSC: 445464(C1R)
CDK: 105098187(C1R)
BACU: 103014234(C1R)
LVE: 103085319(C1R)
OOR: 101269650(C1R)
DLE: 111176709(C1R)
PCAD: 102987961(C1R)
ECB: 100060297(C1R)
EPZ: 103563701(C1R)
EAI: 106847307(C1R)
MYB: 102255103(C1R)
MYD: 102754399(C1R)
MNA: 107544003(C1R)
HAI: 109373632(C1R)
DRO: 112321892(C1R)
PALE: 102897527(C1R)
RAY: 107519842(C1R)
MJV: 108384823(C1R)
LAV: 100658090(C1R)
TMU: 101359146
MDO: 100016799(C1R) 100016836
SHR: 100925028(C1R)
PCW: 110213817(C1R) 110213855(C1RL)
OAA: 100090998(C1R)
GGA: 418295(C1R)
MGP: 100549554(C1R)
CJO: 107318585(C1R)
NMEL: 110398250(C1R)
APLA: 101791982(C1R)
ACYG: 106047869(C1R)
TGU: 100224962(C1R)
LSR: 110480854(C1R)
SCAN: 103812469(C1R)
GFR: 102043291(C1R)
FAB: 101809091(C1R)
PHI: 102111934(C1R)
PMAJ: 107207095(C1R)
CCAE: 111938131(C1R)
CCW: 104687137(C1R)
ETL: 114058183(C1R)
FPG: 101920055(C1R)
FCH: 102054607(C1R)
CLV: 102093497(C1R)
EGZ: 104126607(C1R)
NNI: 104009783(C1R)
ACUN: 113479831(C1R)
PADL: 103921890(C1R)
AAM: 106497213(C1R)
ASN: 102373027(C1R)
AMJ: 102572656(C1R)
PSS: 102453764(C1R)
CMY: 102947496(C1R)
ACS: 100558220(c1r)
PVT: 110084645(C1R)
PBI: 103064088(C1R)
PMUR: 107285781(C1R)
TSR: 106553558(C1R)
PMUA: 114587897(C1R)
GJA: 107111991(C1R)
XLA: 735208
XTR: 613057(c1r)
NPR: 108784393(C1R)
SRX: 107724791
SANH: 107671893
IPU: 108263468(C1R) 108268478
PHYP: 113525156
EEE: 113574789
LCO: 104932556
NCC: 104941465
MZE: 101486209
OLA: 101173495
XMA: 102236483(c1r)
XCO: 114142160(c1r)
CVG: 107082193
NFU: 107379532
KMR: 108235398
ALIM: 106529165
AOCE: 111586786
LCF: 108880662
SDU: 111230024
SLAL: 111669859
HCQ: 109515279
MALB: 109966183
ELS: 105019078
SFM: 108924259
PKI: 111835375
LCM: 102354841(C1R)
CMK: 103172446
SPU: 105445673
 » show all
Reference
PMID:3021205
  Authors
Leytus SP, Kurachi K, Sakariassen KS, Davie EW
  Title
Nucleotide sequence of the cDNA coding for human complement C1r.
  Journal
Biochemistry 25:4855-63 (1986)
DOI:10.1021/bi00365a020
  Sequence
[hsa:715]
Reference
  Authors
Sim RB, Tsiftsoglou SA
  Title
Proteases of the complement system.
  Journal
Biochem Soc Trans 32:21-7 (2004)
DOI:10.1042/bst0320021

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