KEGG   ORTHOLOGY: K01331
Entry
K01331                      KO                                     

Name
C1S
Definition
complement component 1, s subcomponent [EC:3.4.21.42]
Pathway
ko04610  Complement and coagulation cascades
ko05133  Pertussis
ko05150  Staphylococcus aureus infection
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H02240  Ehlers-Danlos syndrome periodontal type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01331  C1S; complement component 1, s subcomponent
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K01331  C1S; complement component 1, s subcomponent
  09171 Infectious disease: bacterial
   05133 Pertussis
    K01331  C1S; complement component 1, s subcomponent
   05150 Staphylococcus aureus infection
    K01331  C1S; complement component 1, s subcomponent
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01331  C1S; complement component 1, s subcomponent
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K01331  C1S; complement component 1, s subcomponent
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.42  complement subcomponent C_overbar_1s_
     K01331  C1S; complement component 1, s subcomponent
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01331  C1S; complement component 1, s subcomponent
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K01331  C1S; complement component 1, s subcomponent
Genes
HSA: 716(C1S)
PTR: 451808(C1S)
PPS: 100991971(C1S)
GGO: 101145266(C1S)
PON: 100432027 100455685(C1S)
NLE: 100599399(C1S)
MCC: 714589(C1S)
MCF: 102134687 102137207(C1S)
CSAB: 103218499 103218857(C1S)
RRO: 104664861 104680080(C1S)
RBB: 108542015
CJC: 100412274(C1S)
SBQ: 101034947(C1S)
MMU: 317677(C1s2) 50908(C1s1)
MPAH: 110314998 110316909(C1s)
RNO: 192262(C1s)
MUN: 110548590(C1s)
CGE: 100759777(C1s)
NGI: 103727488(C1s)
HGL: 101697979(C1s)
CCAN: 109682778(C1s)
OCU: 100348898(C1S)
TUP: 102487452 102496444(C1S)
CFA: 486714(C1S)
VVP: 112917318(C1S)
AML: 100472516(C1S)
UMR: 103656176(C1S)
UAH: 113257945(C1S)
ORO: 101377797(C1S)
ELK: 111159747
FCA: 101088676(C1S)
PTG: 102948650(C1S)
PPAD: 109276089(C1S)
AJU: 106965335(C1S)
BTA: 767827(C1S)
BOM: 102285301(C1S)
BIU: 109558903(C1S)
BBUB: 102392362(C1S)
CHX: 102189289(C1S)
OAS: 101107688(C1S)
SSC: 397274(C1S)
CFR: 102513921(C1S)
CDK: 105098188(C1S)
BACU: 103003533(C1S)
LVE: 103085588(C1S)
OOR: 101269409(C1S)
DLE: 111176708(C1S)
PCAD: 102987496(C1S)
ECB: 100060261(C1S)
EPZ: 103563702(C1S)
EAI: 106847309(C1S)
MYB: 102255615(C1S)
MYD: 102755154(C1S)
MNA: 107544114(C1S)
HAI: 109373658(C1S)
DRO: 112321891(C1S)
PALE: 102897110(C1S)
RAY: 107519836(C1S)
MJV: 108384826(C1S)
LAV: 100676140(C1S)
TMU: 101344169
MDO: 100016766(C1S)
SHR: 100917190(C1S)
PCW: 110213806(C1S)
OAA: 100085003(C1S)
GGA: 418294(C1S)
MGP: 100549400(C1S)
CJO: 107318599(C1S)
NMEL: 110398269(C1S)
APLA: 101791779(C1S)
ACYG: 106047861(C1S)
TGU: 100222051(C1S)
LSR: 110480852(C1S)
SCAN: 103812468(C1S)
GFR: 102043120(C1S)
FAB: 101809291(C1S)
PHI: 102112114(C1S)
PMAJ: 107207087(C1S)
CCAE: 111938155(C1S)
CCW: 104687135(C1S)
ETL: 114058181(C1S)
FPG: 101915039(C1S)
FCH: 102049047(C1S)
CLV: 102093208(C1S)
EGZ: 104126544(C1S)
NNI: 104009512(C1S)
ACUN: 113479841(C1S)
PADL: 103920878(C1S)
AAM: 106497286(C1S)
ASN: 102373441(C1S)
AMJ: 102572422(C1S)
PSS: 102460272
CMY: 102946599(C1S)
CPIC: 101944626(C1S)
ACS: 100558615(c1s) 100560720
PVT: 110084650(C1S)
PBI: 103065043(C1S)
PMUR: 107285780(C1S)
TSR: 106553465(C1S)
PMUA: 114587883(C1S)
XLA: 733422(c1s.L)
XTR: 613055(c1s)
NPR: 108784394(C1S)
AMEX: 103027368
EEE: 113574793
NCC: 104941464
MZE: 105940904
ONL: 100711586
CVG: 107082194
ALIM: 106529166
LCF: 108880738
BPEC: 110163037
SALP: 112074549
ELS: 105009774
PKI: 111835376
LCM: 102354579(C1S)
 » show all
Reference
PMID:3500856
  Authors
Mackinnon CM, Carter PE, Smyth SJ, Dunbar B, Fothergill JE
  Title
Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence.
  Journal
Eur J Biochem 169:547-53 (1987)
DOI:10.1111/j.1432-1033.1987.tb13644.x
  Sequence
[hsa:716]
Reference
  Authors
Sim RB, Tsiftsoglou SA
  Title
Proteases of the complement system.
  Journal
Biochem Soc Trans 32:21-7 (2004)
DOI:10.1042/bst0320021

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