KEGG   ORTHOLOGY: K01363
Entry
K01363                      KO                                     

Name
CTSB
Definition
cathepsin B [EC:3.4.22.1]
Pathway
ko04140  Autophagy - animal
ko04142  Lysosome
ko04210  Apoptosis
ko04612  Antigen processing and presentation
ko04621  NOD-like receptor signaling pathway
ko04924  Renin secretion
Disease
H00932  Tropical calcific pancreatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K01363  CTSB; cathepsin B
   04140 Autophagy - animal
    K01363  CTSB; cathepsin B
  09143 Cell growth and death
   04210 Apoptosis
    K01363  CTSB; cathepsin B
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K01363  CTSB; cathepsin B
   04612 Antigen processing and presentation
    K01363  CTSB; cathepsin B
  09152 Endocrine system
   04924 Renin secretion
    K01363  CTSB; cathepsin B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01363  CTSB; cathepsin B
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K01363  CTSB; cathepsin B
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K01363  CTSB; cathepsin B
   00536 Glycosaminoglycan binding proteins
    K01363  CTSB; cathepsin B
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.1  cathepsin B
     K01363  CTSB; cathepsin B
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C1: papain family
   K01363  CTSB; cathepsin B
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Papain family
   K01363  CTSB; cathepsin B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   K01363  CTSB; cathepsin B
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Others
   K01363  CTSB; cathepsin B
Genes
HSA: 1508(CTSB)
PTR: 463993(CTSB)
PPS: 100987583(CTSB)
GGO: 101152544(CTSB)
PON: 100173564(CTSB)
NLE: 100604807(CTSB)
MCC: 100424758(CTSB)
MCF: 101865017(CTSB)
CSAB: 103215319(CTSB)
RRO: 104679114(CTSB)
RBB: 108536689(CTSB)
CJC: 100389833(CTSB)
SBQ: 101047879(CTSB)
MMU: 13030(Ctsb)
MCAL: 110309044(Ctsb)
MPAH: 110325177(Ctsb)
RNO: 64529(Ctsb)
MUN: 110541758(Ctsb)
CGE: 100756995(Ctsb)
NGI: 103729973(Ctsb)
HGL: 101709008(Ctsb)
CCAN: 109682023(Ctsb)
OCU: 100101593(CTSB)
TUP: 102483590(CTSB)
CFA: 486077(CTSB)
VVP: 112926754(CTSB)
AML: 100476830(CTSB)
UMR: 103675931(CTSB)
UAH: 113269920(CTSB)
ORO: 101375531(CTSB)
ELK: 111154231
FCA: 101084873(CTSB)
PTG: 102968829(CTSB)
PPAD: 109262395(CTSB)
AJU: 106975817(CTSB)
BTA: 281105(CTSB)
BOM: 102284921(CTSB)
BIU: 109562776(CTSB)
BBUB: 102410738(CTSB)
CHX: 102173295(CTSB)
OAS: 780470(CTSB)
SSC: 100037961(CTSB)
CFR: 102522938(CTSB)
CDK: 105101888(CTSB)
BACU: 102999231(CTSB)
LVE: 103090468(CTSB)
OOR: 101283436(CTSB)
DLE: 111185365(CTSB)
PCAD: 102983822(CTSB)
ECB: 100060963(CTSB)
EPZ: 103558180(CTSB)
EAI: 106822582(CTSB)
MYB: 102240887(CTSB)
MYD: 102761828 102771390(CTSB)
MNA: 107527504(CTSB)
HAI: 109379548(CTSB)
DRO: 112312250(CTSB)
PALE: 102883622(CTSB)
RAY: 107507224(CTSB)
MJV: 108402364(CTSB)
LAV: 100663899(CTSB)
TMU: 101341172
MDO: 100032681(CTSB)
SHR: 100920513(CTSB)
PCW: 110207612(CTSB)
OAA: 100082449(CTSB)
GGA: 396329(CTSB)
MGP: 100544902(CTSB)
CJO: 107312410(CTSB)
NMEL: 110395601(CTSB)
APLA: 101794268(CTSB)
ACYG: 106038130(CTSB)
TGU: 100190482(CTSB)
LSR: 110481443(CTSB)
SCAN: 103821275(CTSB)
GFR: 102045641(CTSB)
FAB: 101815778(CTSB)
PHI: 102102206(CTSB)
PMAJ: 107202448(CTSB)
CCAE: 111927375(CTSB)
CCW: 104696872(CTSB)
ETL: 114069201(CTSB)
FPG: 101920597(CTSB)
FCH: 102059814(CTSB)
CLV: 102084749(CTSB)
EGZ: 104127263(CTSB)
NNI: 104014687(CTSB)
ACUN: 113478278(CTSB)
PADL: 103913274(CTSB)
AAM: 106483924(CTSB)
ASN: 102378401(CTSB)
AMJ: 102573171(CTSB)
PSS: 102453723(CTSB)
CMY: 102930234(CTSB)
CPIC: 101943093(CTSB)
ACS: 100563878(ctsb)
PVT: 110070450(CTSB)
PBI: 103051970(CTSB)
PMUR: 107289312(CTSB) 107301213
PMUA: 114594906(CTSB)
GJA: 107112866(CTSB)
XLA: 379257(ctsb.S) 380102(ctsb.L)
XTR: 394833(ctsb)
NPR: 108797919(CTSB)
DRE: 406645(ctsba) 569298(ctsbb)
SANH: 107661356 107674100(ctsb)
IPU: 108269890(ctsb)
PHYP: 113533939(ctsb)
EEE: 113571882 113583676(ctsb)
OLA: 101160638(ctsb) 101165526
PRET: 103457574(ctsb) 103462835
CVG: 107083374(ctsb) 107092135
NFU: 107377587(ctsb) 107381178
KMR: 108237382(ctsba) 108240069
ALIM: 106516844 106523671(ctsb)
AOCE: 111589113
CSEM: 103379409 103380823(ctsb)
HCQ: 109528616(ctsb)
BPEC: 110172821(ctsb)
MALB: 109953279 109954568(ctsb)
SASA: 100195493(catb) 106607936(ctsb) 106611360(CATB)
ELS: 105015425(ctsb)
LCM: 102351271(CTSB)
CMK: 103171629(ctsb)
RTP: 109925170(ctsb)
BFO: 118404562
CIN: 100176002
SPU: 582922
SKO: 100373078
DME: Dmel_CG10992(CtsB1)
DER: 6550867
DSE: 6618459
DSI: Dsimw501_GD15875(Dsim_GD15875)
DAN: 6505053
DSR: 110183232
DPE: 6598439
DMN: 108164733
DWI: 6644681
DAZ: 108619787
DNV: 108656605
DHE: 111603094
DVI: 6632024
MDE: 101887961
LCQ: 111690963
NVL: 108557216
BMOR: 692390
BMAN: 114240639
PMAC: 106710142
PRAP: 111001540
HAW: 110376576
PXY: 105390633
API: 100144775(Catb-348) 100144778(Catb-1852) 100144780(Catb-912) 100144781(Catb-2744) 100144782(Catb-1418) 100144784(Catb-1674) 100144785(Catb-16a) 100144787(Catb-84) 100144788(Catb-5880) 100144790(Catb-3098) 100144791(Catb-16d2) 100144792 100144794(Catb-1874) 100144795(Catb-3483) 100144796(Catb-10270) 100159094 100159833 100159850 100159943 100160743 100161139 100162979 100164098 100164982 100169466 103307611
ZNE: 110830373
PVM: 113808173
PTEP: 107439411
CEL: CELE_C25B8.3(cpr-6) CELE_C52E4.1(cpr-1) CELE_F32H5.1(F32H5.1) CELE_F36D3.9(cpr-2) CELE_F44C4.3(cpr-4) CELE_F57F5.1(F57F5.1) CELE_T10H4.12(cpr-3) CELE_W07B8.1(cpr-8) CELE_W07B8.4(W07B8.4) CELE_W07B8.5(cpr-5)
BMY: Bm1_33735
CRG: 105328916
OBI: 106873643
LAK: 106173360
EGL: EGR_00222
DGT: 114527506
CPAP: 110814176
CIT: 102614215
TCC: 18613845
GAB: 108453748
EGR: 104434154
VRA: 106757800
VAR: 108329369
VUN: 114178665
CCAJ: 109797052
LJA: Lj0g3v0055079.1(Lj0g3v0055079.1) Lj1g3v4819970.1(Lj1g3v4819970.1)
ADU: 107492262
AIP: 107646004
FVE: 101292935
RCN: 112193527
PPER: 18788067
PMUM: 103327235
PAVI: 110764573
MDM: 103405978
PXB: 103933562
ZJU: 107426196
CSV: 101206928
CMO: 103502979
MCHA: 111025675
CMAX: 111470792
CMOS: 111439194
CPEP: 111800718
RCU: 8270811
JCU: 105642738
VVI: 100267480
INI: 109152432
SIND: 105162975
DCR: 108203066
BVG: 104908565
SOE: 110794569
NNU: 104590324
OSA: 9267789
SBI: 110432844
ZMA: 100283781(cl31697_1)
PDA: 103696640
EGU: 105034333
AOF: 109831962
ATR: 18430031
SMIN: v1.2.004193.t1(symbB.v1.2.004193.t1) v1.2.027715.t1(symbB.v1.2.027715.t1) v1.2.034047.t1(symbB.v1.2.034047.t1)
 » show all
Reference
PMID:8112600
  Authors
Cao L, Taggart RT, Berquin IM, Moin K, Fong D, Sloane BF
  Title
Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene.
  Journal
Gene 139:163-9 (1994)
DOI:10.1016/0378-1119(94)90750-1
Reference
  Authors
Aggarwal N, Sloane BF
  Title
Cathepsin B: multiple roles in cancer.
  Journal
Proteomics Clin Appl 8:427-37 (2014)
DOI:10.1002/prca.201300105
  Sequence
[hsa:1508]

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