Entry |
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Symbol |
MMP9
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Name |
matrix metalloproteinase-9 (gelatinase B) [EC: 3.4.24.35]
|
Pathway |
map04670 | Leukocyte transendothelial migration |
map05202 | Transcriptional misregulation in cancer |
map05418 | Fluid shear stress and atherosclerosis |
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Disease |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09150 Organismal Systems
09151 Immune system
04657 IL-17 signaling pathway
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
04670 Leukocyte transendothelial migration
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09152 Endocrine system
04915 Estrogen signaling pathway
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
04926 Relaxin signaling pathway
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05202 Transcriptional misregulation in cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05206 MicroRNAs in cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05205 Proteoglycans in cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09162 Cancer: specific types
05219 Bladder cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05215 Prostate cancer
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09172 Infectious disease: viral
05161 Hepatitis B
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05418 Fluid shear stress and atherosclerosis
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
05415 Diabetic cardiomyopathy
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
Enzymes [BR:ko01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.35 gelatinase B
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
Family M10
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B)
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Genes |
» show all
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Reference |
|
Authors |
Wilhelm SM, Collier IE, Marmer BL, Eisen AZ, Grant GA, Goldberg GI |
Title |
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. |
Journal |
J Biol Chem 264:17213-21 (1989) |
Sequence |
|
Reference |
|
Authors |
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C |
Title |
Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models. |
Journal |
|
Reference |
|
Authors |
Amalinei C, Caruntu ID, Balan RA |
Title |
Biology of metalloproteinases. |
Journal |
Rom J Morphol Embryol 48:323-34 (2007) |
Reference |
|
Authors |
Hua H, Li M, Luo T, Yin Y, Jiang Y |
Title |
Matrix metalloproteinases in tumorigenesis: an evolving paradigm. |
Journal |
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