KEGG   ORTHOLOGY: K01404
Entry
K01404                      KO                                     

Name
GP63
Definition
leishmanolysin [EC:3.4.24.36]
Pathway
ko05140  Leishmaniasis
ko05143  African trypanosomiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K01404  GP63; leishmanolysin
   05143 African trypanosomiasis
    K01404  GP63; leishmanolysin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01404  GP63; leishmanolysin
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K01404  GP63; leishmanolysin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.36  leishmanolysin
     K01404  GP63; leishmanolysin
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M8: leishmanolysin family
   K01404  GP63; leishmanolysin
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Antigens
  K01404  GP63; leishmanolysin
Genes
ATH: AT5G42620
ALY: 9299837
CRB: 17875516
CSAT: 104725219 104760706 104771388
EUS: EUTSA_v10022547mg
BRP: 103828018
BNA: 106349526 111198782
BOE: 106342481
RSZ: 108855134 108855135
THJ: 104806880 104809128
CPAP: 110813552
CIT: 102621178
TCC: 18591336
EGR: 104416623
LJA: Lj5g3v2297750.1(Lj5g3v2297750.1) Lj5g3v2297750.2(Lj5g3v2297750.2)
ADU: 107495963
AIP: 107605731
FVE: 101308254
RCN: 112172746
PPER: 18791128
PMUM: 103320808
PAVI: 110762610
MDM: 103420931
ZJU: 107420265
CSV: 101217702
CMO: 103487946
MCHA: 111013969
RCU: 8260940
JCU: 105633745
QSU: 112011988
VVI: 100257368
SLY: 101248771
SPEN: 107017811
SOT: 102596537
CANN: 107867059
NSY: 104212740
NTO: 104091581
NAU: 109208548
INI: 109170300
BVG: 104898653
SOE: 110785245
NNU: 104595772
OSA: 4334001
DOSA: Os03t0731500-01(Os03g0731500)
OBR: 102704227
BDI: 100831389
ATS: 109780249
SBI: 8059951
ZMA: 103643963
SITA: 101779712
PDA: 103707501
EGU: 105055836
DCT: 110100801
PEQ: 110031986
AOF: 109822512
ATR: 18445929
DFA: DFA_06007(sigB)
EHI: EHI_042870(111.t00003) EHI_200230(30.t00006)
SPAR: SPRG_12195
LPAN: LPMP_100410(GP63-1) LPMP_100420(GP63-2) LPMP_100430(GP63-3) LPMP_100440(GP63-4) LPMP_311850
 » show all
Reference
PMID:3346625
  Authors
Button LL, McMaster WR
  Title
Molecular cloning of the major surface antigen of leishmania.
  Journal
J Exp Med 167:724-9 (1988)
DOI:10.1084/jem.167.2.724
  Sequence
Reference
  Authors
Joshi PB, Kelly BL, Kamhawi S, Sacks DL, McMaster WR
  Title
Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor.
  Journal
Mol Biochem Parasitol 120:33-40 (2002)
DOI:10.1016/S0166-6851(01)00432-7

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