Entry |
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Name |
methenyltetrahydromethanopterin cyclohydrolase;
5,10-methenyltetrahydromethanopterin cyclohydrolase;
N5,N10-methenyltetrahydromethanopterin cyclohydrolase;
methenyl-H4MPT cyclohydrolase;
5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)
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Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
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Sysname |
5,10-methenyltetrahydromethanopterin 10-hydrolase (ring-opening)
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Reaction(IUBMB) |
5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = 5-formyl-5,6,7,8-tetrahydromethanopterin [RN: R03464]
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Reaction(KEGG) |
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Substrate |
5,10-methenyl-5,6,7,8-tetrahydromethanopterin [CPD: C04330];
H2O [CPD: C00001]
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Product |
5-formyl-5,6,7,8-tetrahydromethanopterin [CPD: C01274]
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Comment |
Methanopterin is a pterin analogue. The enzyme is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.
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History |
EC 3.5.4.27 created 1989
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Pathway |
ec01120 | Microbial metabolism in diverse environments |
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Orthology |
K01499 | methenyltetrahydromethanopterin cyclohydrolase |
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Genes |
» show all
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Reference |
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Authors |
Donnelly MI, Escalante-Semerena JC, Rinehart KL Jr, Wolfe RS. |
Title |
Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 3.5.4.27 |
ExPASy - ENZYME nomenclature database: | 3.5.4.27 |
UM-BBD (Biocatalysis/Biodegradation Database): | 3.5.4.27 |
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