KEGG   ORTHOLOGY: K02150
Entry
K02150                      KO                                     

Symbol
ATPeV1E, ATP6E
Name
V-type H+-transporting ATPase subunit E
Pathway
map00190  Oxidative phosphorylation
map01100  Metabolic pathways
map04145  Phagosome
map04150  mTOR signaling pathway
map04721  Synaptic vesicle cycle
map04966  Collecting duct acid secretion
map05110  Vibrio cholerae infection
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05165  Human papillomavirus infection
map05323  Rheumatoid arthritis
Module
M00160  V-type ATPase, eukaryotes
Disease
H00557  Cutis laxa
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
  09156 Nervous system
   04721 Synaptic vesicle cycle
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
  09163 Immune disease
   05323 Rheumatoid arthritis
    K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
Other DBs
COG: COG1390
TC: 3.A.2.2
Genes
HSA: 529(ATP6V1E1) 90423(ATP6V1E2)
PTR: 100612241(ATP6V1E2) 458633(ATP6V1E1)
PPS: 100978055(ATP6V1E2) 100988766(ATP6V1E1)
GGO: 101136791(ATP6V1E2) 101140519(ATP6V1E1)
PON: 100439059(ATP6V1E2) 100442385(ATP6V1E1)
NLE: 100593410(ATP6V1E1) 100607588(ATP6V1E2)
MCC: 709739(ATP6V1E1) 714746(ATP6V1E2)
MCF: 101866302(ATP6V1E1) 102121520(ATP6V1E2)
CSAB: 103220345(ATP6V1E2) 103222872(ATP6V1E1)
CATY: 105590594(ATP6V1E2) 105591260(ATP6V1E1)
PANU: 101010034(ATP6V1E1) 101023443(ATP6V1E2)
RRO: 104663179(ATP6V1E2) 104676301(ATP6V1E1)
RBB: 108522482(ATP6V1E2) 108541724(ATP6V1E1)
TFN: 117062361(ATP6V1E2) 117092750 117094413 117096074(ATP6V1E1)
PTEH: 111526403(ATP6V1E1) 111531945 111535640 111550447(ATP6V1E2)
CJC: 100396342(ATP6V1E2) 100402779(ATP6V1E1)
SBQ: 101050200(ATP6V1E1) 101052229(ATP6V1E2)
MMUR: 105861868(ATP6V1E1) 105867065(ATP6V1E2)
MMU: 11973(Atp6v1e1) 74915(Atp6v1e2)
MCAL: 110284052(Atp6v1e2) 110295768(Atp6v1e1)
MPAH: 110316108(Atp6v1e1) 110335958(Atp6v1e2)
RNO: 297566(Atp6v1e1) 366545(Atp6v1e2)
MCOC: 116079860(Atp6v1e2) 116099516(Atp6v1e1)
MUN: 110546059(Atp6v1e1) 110552341(Atp6v1e2)
CGE: 100755187(Atp6v1e1) 100765179(Atp6v1e2)
PLEU: 114700740(Atp6v1e1) 114709621(Atp6v1e2)
NGI: 103725755(Atp6v1e2) 103745895(Atp6v1e1)
HGL: 101713169(Atp6v1e1) 101715155(Atp6v1e2)
CPOC: 100722091(Atp6v1e2) 100725691(Atp6v1e1)
CCAN: 109678224(Atp6v1e1) 109700148(Atp6v1e2)
OCU: 100353383(ATP6V1E1) 100354167(ATP6V1E2)
OPI: 101520811(ATP6V1E2) 101530705(ATP6V1E1)
TUP: 102477361(ATP6V1E1) 102477755 102500238(ATP6V1E2)
CFA: 477740(ATP6V1E1) 481359(ATP6V1E2)
VVP: 112915335(ATP6V1E2) 112917436(ATP6V1E1)
VLG: 121480260(ATP6V1E1) 121490545(ATP6V1E2) 121500085
AML: 100464522(ATP6V1E1) 100469216(ATP6V1E2)
UMR: 103671228(ATP6V1E2) 103675697(ATP6V1E1)
UAH: 113246115(ATP6V1E2) 113258061(ATP6V1E1)
ORO: 101363332(ATP6V1E2) 101370142(ATP6V1E1) 101383455
MPUF: 101680354(ATP6V1E2) 101684224(ATP6V1E1)
EJU: 114209667(ATP6V1E2) 114216207 114222483(ATP6V1E1) 114223638 114226472
MLX: 118007470(ATP6V1E2) 118025820(ATP6V1E1)
FCA: 101081815(ATP6V1E1) 101101208(ATP6V1E2)
PYU: 121016331(ATP6V1E2) 121022068(ATP6V1E1)
PBG: 122473778(ATP6V1E1) 122496802(ATP6V1E2)
PTG: 102953832(ATP6V1E1) 102957768(ATP6V1E2)
PPAD: 109276273(ATP6V1E1) 109279220(ATP6V1E2)
AJU: 106965419(ATP6V1E1) 106977229(ATP6V1E2)
HHV: 120241028(ATP6V1E2) 120243760(ATP6V1E1)
BTA: 287017(ATP6V1E1) 540113(ATP6V1E2)
BOM: 102264759(ATP6V1E2) 102278885(ATP6V1E1)
BIU: 109559780(ATP6V1E1) 109566047(ATP6V1E2)
BBUB: 102401682(ATP6V1E1) 102405483(ATP6V1E2)
CHX: 102169483(ATP6V1E2) 102174547(ATP6V1E1)
OAS: 101110043(ATP6V1E2) 494438(ATP6V1E1)
ODA: 120851738(ATP6V1E2) 120857833(ATP6V1E1)
CCAD: 122423035(ATP6V1E1) 122427754 122441639(ATP6V1E2) 122453727
SSC: 100156112(ATP6V1E1) 100736975(ATP6V1E2)
CFR: 102510520(ATP6V1E1) 106729767(ATP6V1E2)
CBAI: 105076098(ATP6V1E1) 105079023(ATP6V1E2)
CDK: 105100739(ATP6V1E1) 105103567(ATP6V1E2)
BACU: 103003818(ATP6V1E2) 103014368(ATP6V1E1)
LVE: 103085259(ATP6V1E2) 103088078(ATP6V1E1)
OOR: 101275163(ATP6V1E1) 101275901(ATP6V1E2)
DLE: 111176589(ATP6V1E1)
PCAD: 102987448(ATP6V1E1) 102989820(ATP6V1E2)
PSIU: 116760545(ATP6V1E1) 116764541(ATP6V1E2)
ECB: 100049854(ATP6V1E1) 100053341(ATP6V1E2)
EPZ: 103559200(ATP6V1E1) 103565438(ATP6V1E2)
EAI: 106826415(ATP6V1E2) 106839440(ATP6V1E1)
MYB: 102240804(ATP6V1E1) 102258315(ATP6V1E2)
MYD: 102754411(ATP6V1E2) 102759586(ATP6V1E1)
MMYO: 118650310(ATP6V1E1) 118669485(ATP6V1E2)
MLF: 102420621(ATP6V1E1) 102425122 102438262(ATP6V1E2)
MNA: 107537725(ATP6V1E1) 107540259(ATP6V1E2)
PKL: 118710782 118717811(ATP6V1E2) 118728791(ATP6V1E1)
HAI: 109374955(ATP6V1E1) 109389902(ATP6V1E2)
DRO: 112298088(ATP6V1E2) 112311685(ATP6V1E1)
SHON: 118995132(ATP6V1E1) 119001257(ATP6V1E2)
AJM: 119044376(ATP6V1E1) 119045594 119049378 119060918(ATP6V1E2)
PDIC: 114500463(ATP6V1E2) 114508618(ATP6V1E1)
MMF: 118624122(ATP6V1E1) 118631000(ATP6V1E2)
RFQ: 117021067 117028887(ATP6V1E1) 117032756(ATP6V1E2)
PALE: 102886616(ATP6V1E1) 102893649(ATP6V1E2)
PGIG: 120607358(ATP6V1E1) 120622103(ATP6V1E2)
RAY: 107500465(ATP6V1E1) 107509568(ATP6V1E2)
MJV: 108400236(ATP6V1E1) 108406402(ATP6V1E2)
TOD: 119247862(ATP6V1E1) 119259340(ATP6V1E2)
LAV: 100654530(ATP6V1E2) 100662195(ATP6V1E1)
MDO: 100017871(ATP6V1E1)
GAS: 123234917 123248936(ATP6V1E1)
SHR: 100927023(ATP6V1E1)
PCW: 110218717(ATP6V1E1)
OAA: 103169025(ATP6V1E1)
GGA: 418162(ATP6V1E1)
PCOC: 116226874(ATP6V1E1)
MGP: 100545200(ATP6V1E1)
CJO: 107315125(ATP6V1E1)
NMEL: 110395645(ATP6V1E1)
APLA: 101793897(ATP6V1E1)
ACYG: 106031039(ATP6V1E1)
TGU: 100190066(ATP6V1E1)
SCAN: 103820466(ATP6V1E1)
PMOA: 120501638(ATP6V1E1)
OTC: 121332880(ATP6V1E1)
PRUF: 121362722(ATP6V1E1)
GFR: 102032230(ATP6V1E1)
FAB: 101822037(ATP6V1E1)
PHI: 102106830(ATP6V1E1)
PMAJ: 107205080(ATP6V1E1)
CCAE: 111928065(ATP6V1E1)
CCW: 104692248(ATP6V1E1)
ETL: 114069024(ATP6V1E1)
FPG: 101914050(ATP6V1E1)
FCH: 102047807(ATP6V1E1)
CLV: 102094154(ATP6V1E1)
EGZ: 104134396(ATP6V1E1)
NNI: 104020205(ATP6V1E1)
ACUN: 113488370(ATP6V1E1)
PADL: 103924361(ATP6V1E1)
AAM: 106488704(ATP6V1E1)
AROW: 112968313(ATP6V1E1)
NPD: 112958318(ATP6V1E1)
DNE: 112993369(ATP6V1E1)
ASN: 102376182(ATP6V1E1)
AMJ: 102574584(ATP6V1E1)
CPOO: 109316450(ATP6V1E1)
GGN: 109296240(ATP6V1E1)
PSS: 102452276(ATP6V1E1)
CMY: 102941447(ATP6V1E1)
CPIC: 101935237(ATP6V1E1)
TST: 117882696(ATP6V1E1)
CABI: 116830088(ATP6V1E1)
MRV: 120408891(ATP6V1E1)
ACS: 100563341(atp6v1e1)
PVT: 110076694(ATP6V1E1)
SUND: 121931098(ATP6V1E1)
PBI: 103057053(ATP6V1E1)
PMUR: 107292280(ATP6V1E1)
TSR: 106542420(ATP6V1E1)
PGUT: 117655877(ATP6V1E1)
VKO: 123016521(ATP6V1E1)
PMUA: 114605954(ATP6V1E1)
ZVI: 118090947(ATP6V1E1)
GJA: 107115455(ATP6V1E1)
XLA: 108712570(atp6v1e1.S) 379457(atp6v1e1.L)
XTR: 394728(atp6v1e1)
NPR: 108791578(ATP6V1E1)
DRE: 108179059(atp6v1e1a) 192335(atp6v1e1b)
IPU: 100528265(atp6v1e1) 108269194(ATP6V1E1)
TRU: 101061664 101071129(atp6v1e1)
LCO: 104940272 109141503(atp6v1e1)
NCC: 104950100(atp6v1e1) 104967770
ELY: 117249226(atp6v1e1b) 117261639(atp6v1e1a)
PLEP: 121949979(atp6v1e1a) 121961355(atp6v1e1b)
SLUC: 116040196(atp6v1e1a) 116060103(atp6v1e1b)
ECRA: 117938827(atp6v1e1b) 117949074(atp6v1e1a)
GAT: 120808731(atp6v1e1a) 120817712(atp6v1e1b)
PPUG: 119196419(atp6v1e1a) 119210390(atp6v1e1b)
MSAM: 119893029(atp6v1e1a) 119918378(atp6v1e1b)
CUD: 121505577(atp6v1e1b) 121514505(atp6v1e1a)
ONL: 100699660 100708725(atp6v1e1)
OAU: 116309391(atp6v1e1a) 116334878(atp6v1e1b)
OML: 112152541(atp6v1e1a) 112158324(atp6v1e1b)
PRET: 103459166 103481182(atp6v1e1)
GAF: 122826206(atp6v1e1b) 122835134(atp6v1e1a)
CVG: 107085735 107097962(atp6v1e1)
CTUL: 119776896(atp6v1e1b)
KMR: 108233293(atp6v1e1b) 108237511(atp6v1e1a)
AOCE: 111567814(atp6v1e1) 111581867
SSEN: 122765725(atp6v1e1b) 122775444(atp6v1e1a)
HHIP: 117757199(atp6v1e1b) 117763255(atp6v1e1a)
XGL: 120793047(atp6v1e1a) 120803307(atp6v1e1b)
HCQ: 109523686 109530352(atp6v1e1)
BPEC: 110161719(atp6v1e1) 110169605
SASA: 106561370(VATE1) 106576269(VATE1) 106609471
ELS: 105018114(atp6v1e1) 105030149
LOC: 102694025(atp6v1e1)
LCM: 102358474(ATP6V1E1)
CMK: 103186128(atp6v1e1b)
RTP: 109932372(atp6v1e1)
BFO: 118406807
BBEL: 109467474
CIN: 100178177
SCLV: 120336440
SPU: 594178
APLC: 110973051
SKO: 100376886
DME: Dmel_CG1088(Vha26)
DER: 6552726
DSE: 6613973
DSI: Dsimw501_GD19797(Dsim_GD19797)
DAN: 6503392
DSR: 110177120
DPE: 6591718
DMN: 108155675
DWI: 6649405
DGR: 6568351
DAZ: 108621520
DNV: 108649886
DHE: 111598511
DVI: 6629563
CCAT: 101462736
BOD: 106622965
MDE: 101899906
SCAC: 106093790
LCQ: 111685233
ACOZ: 120948496
AARA: 120902102
AAG: 5575718
AALB: 109431782
CPII: 120412961
AME: 552720
ACER: 108001305
BIM: 100740337
BBIF: 117205563
BVK: 117232661
BVAN: 117156340
BTER: 100648858
BPYO: 122567316
CCAL: 108631035
OBB: 114872911
MGEN: 117220070
NMEA: 116426498
CGIG: 122398684
SOC: 105194985
MPHA: 105837802
AEC: 105155000
ACEP: 105626877
PBAR: 105426346
VEM: 105566824
HST: 105184977
DQU: 106748317
CFO: 105255988
FEX: 115243794
LHU: 105669829
PGC: 109857885
OBO: 105284472
PCF: 106785558
PFUC: 122520565
VPS: 122637573
NVI: 100115358
CSOL: 105362132
TPRE: 106658986
MDL: 103576148
CGLO: 123259593
FAS: 105263781
DAM: 107037574
AGIF: 122858158
CCIN: 107273366
TCA: 659201
DPA: 109539375
AGB: 108909363
LDC: 111516570
NVL: 108567515
PPYR: 116173804
OTU: 111423183
BMOR: 732990
BMAN: 114239390
MSEX: 115448230
BANY: 112047362
PPOT: 106104299
PRAP: 110995368
ZCE: 119829125
HAW: 110377195
TNL: 113499397
FOC: 113218069
ZNE: 110833370
CSEC: 111863919
FCD: 110846151
PVM: 113815659
PJA: 122253849
HAZT: 108679798
EAF: 111704957
RMP: 119163995
VDE: 111252847
VJA: 111267355
TUT: 107370305
DPTE: 113798004
CSCU: 111633568
PTEP: 107440117
SDM: 118186897
CEL: CELE_C17H12.14(vha-8)
CBR: CBG_05372(Cbr-vha-8)
BMY: BM_BM13886(Bma-vha-8)
TSP: Tsp_00958
PCAN: 112565692
BGT: 106071441
GAE: 121372599
MYI: 110464086
PMAX: 117328229
OBI: 106878891
OSN: 115215132
LAK: 106178177
EGL: EGR_05567
NVE: 5510801
EPA: 110232990
ATEN: 116298582
ADF: 107336265
AMIL: 114968256
PDAM: 113673510
SPIS: 111326741
DGT: 114531728
HMG: 100209716
AQU: 100634675
ATH: AT1G64200(VHA-E3) AT3G08560(VHA-E2) AT4G11150(TUF)
CPAP: 110809449
LJA: Lj0g3v0349569.1(Lj0g3v0349569.1) Lj4g3v3002500.1(Lj4g3v3002500.1)
MNT: 21395317
CSV: 101217221
CMO: 103491820
BHJ: 120069691
MCHA: 111023388
RCU: 8287721
JCU: 105629139
DOSA: Os01t0222500-01(Os01g0222500) Os01t0659200-01(Os01g0659200) Os05t0480700-01(Os05g0480700)
DCT: 110104928
PEQ: 110022312
VCN: VOLCADRAFT_75406(atpve1)
APRO: F751_2021
SCE: YOR332W(VMA4)
ERC: Ecym_5062
KMX: KLMA_50109(VMA4)
NCS: NCAS_0F01750(NCAS0F01750)
NDI: NDAI_0H02600(NDAI0H02600)
TPF: TPHA_0N00500(TPHA0N00500)
TBL: TBLA_0E01860(TBLA0E01860)
TDL: TDEL_0H03880(TDEL0H03880)
KAF: KAFR_0E02370(KAFR0E02370)
PIC: PICST_60924(VMA4)
CAL: CAALFM_CR01970CA(VMA4)
CDU: CD36_26910(VMA4)
SLB: AWJ20_4906(VMA4)
BNN: FOA43_001494(VMA4)
BBRX: BRETT_001429(VMA4)
NCR: NCU07446(vma-4)
NTE: NEUTE1DRAFT149253(NEUTE1DRAFT_149253)
MGR: MGG_02770
SSCK: SPSK_09729
MAW: MAC_00858
MAJ: MAA_07382
CMT: CCM_03295
BFU: BCIN_09g06160(Bcvma4)
MBE: MBM_07316
ANI: AN8674.2
ANG: ANI_1_1056104(An12g08760)
ABE: ARB_02018
TVE: TRV_05848
PTE: PTT_12808
SPO: SPAC11E3.07(vma4)
CNE: CNA05420
CNB: CNBA5250
TASA: A1Q1_05013
ABP: AGABI1DRAFT86556(AGABI1DRAFT_86556)
ABV: AGABI2DRAFT195316(AGABI2DRAFT_195316)
MGL: MGL_2643
MRT: MRET_0444
DDI: DDB_G0275701(vatE)
DFA: DFA_03992(vatE)
EHI: EHI_182550(9.t00013) EHI_182560(9.t00012)
PCB: PCHAS_083560(PC000234.01.0)
TAN: TA17420
TPV: TP03_0853
BBO: BBOV_I000090(16.m00774)
CPV: cgd8_360
SMIN: v1.2.024271.t1(symbB.v1.2.024271.t1)
EHX: EMIHUDRAFT_433060(ATPVE)
 » show all
Reference
  Authors
Sun-Wada GH, Imai-Senga Y, Yamamoto A, Murata Y, Hirata T, Wada Y, Futai M
  Title
A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.
  Journal
J Biol Chem 277:18098-105 (2002)
DOI:10.1074/jbc.M111567200
  Sequence
[mmu:74915]
Reference
PMID:8250920
  Authors
van Hille B, Vanek M, Richener H, Green JR, Bilbe G
  Title
Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.
  Journal
Biochem Biophys Res Commun 197:15-21 (1993)
DOI:10.1006/bbrc.1993.2434
  Sequence
[hsa:529]
Reference
  Authors
Imai-Senga Y, Sun-Wada GH, Wada Y, Futai M
  Title
A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E.
  Journal
Gene 289:7-12 (2002)
DOI:10.1016/S0378-1119(02)00542-5
  Sequence
[hsa:90423]

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