KEGG ORTHOLOGY: K02216

ORTHOLOGY: K02216

Entry

K02216                      KO

Symbol

CHEK1

Name

serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]

Pathway

map04110

Cell cycle

map04111

Cell cycle - yeast

map04113

Meiosis - yeast

map04115

p53 signaling pathway

map04218

Cellular senescence

map05166

Human T-cell leukemia virus 1 infection

map05170

Human immunodeficiency virus 1 infection

map05203

Viral carcinogenesis

Disease

H01897

Oocyte/zygote/embryo maturation arrest

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04111 Cell cycle - yeast
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04113 Meiosis - yeast
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04115 p53 signaling pathway
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   04218 Cellular senescence
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
   05170 Human immunodeficiency virus 1 infection
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K02216  CHEK1; serine/threonine-protein kinase CHEK1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K02216  CHEK1; serine/threonine-protein kinase CHEK1
Protein kinases [BR:ko01001]
Serine/threonine kinases: CAMK group
  CAMKL family
   K02216  CHEK1; serine/threonine-protein kinase CHEK1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Check point factors
   Other check point factors
    K02216  CHEK1; serine/threonine-protein kinase CHEK1

Other DBs

COG:

COG0515

Genes

HSA:	1111(CHEK1)

PTR:	739836(CHEK1)

PPS:	100982317(CHEK1)

GGO:	101131993(CHEK1)

PON:	100436550(CHEK1)

PPYG:

129007121(CHEK1)

NLE:	100596673(CHEK1)

HMH:	116477131(CHEK1)

SSYN:

129479838(CHEK1)

MCC:	713358(CHEK1)

MCF:	101926004(CHEK1)

MTHB:

126934853

MNI:	105476258(CHEK1)

CSAB:

103248769(CHEK1)

CATY:

105582604(CHEK1)

PANU:

101019580(CHEK1)

TGE:	112606274(CHEK1)

MLEU:

105554711(CHEK1)

RRO:	104653937(CHEK1)

RBB:	108542336(CHEK1)

TFN:	117080890(CHEK1)

PTEH:

111540298(CHEK1)

CANG:

105506457(CHEK1)

CJC:	100405400(CHEK1)

SBQ:	101044792(CHEK1)

CIMI:

108300793(CHEK1)

ANAN:

105717868(CHEK1)

CSYR:

103273961(CHEK1)

MMUR:

105881584(CHEK1)

LCAT:

123641207(CHEK1)

PCOQ:

105821450(CHEK1)

OGA:	100942218(CHEK1)

MMU:	12649(Chek1)

MCAL:

110301495(Chek1)

MPAH:

110327308(Chek1)

RNO:	140583(Chek1)

MCOC:

116071915(Chek1)

ANU:	117699162(Chek1)

MUN:	110549439(Chek1)

CGE:	100751099(Chek1)

MAUA:

101843181(Chek1)

PROB:

127231512(Chek1)

PLEU:

114684003(Chek1)

MORG:

121451627(Chek1)

MFOT:

126490587

AAMP:

119809693(Chek1)

NGI:	103735579(Chek1)

HGL:	101701035(Chek1)

CPOC:

100719613(Chek1)

CCAN:

109700303(Chek1)

DORD:

105980875(Chek1)

DSP:	122104226(Chek1) 122123350

PLOP:

125349506(Chek1)

NCAR:

124958320

MMMA:

107153495(Chek1)

OCU:

100345729

OPI:	101533794(CHEK1)

TUP:	102480757(CHEK1)

GVR:	103583154 103608913(CHEK1)

CFA:	609767(CHEK1)

CLUD:

112671112(CHEK1)

VVP:	112920276(CHEK1)

VLG:	121500173(CHEK1)

NPO:	129497889(CHEK1)

AML:	100467858(CHEK1)

UMR:	103660629(CHEK1)

UAH:	113259903(CHEK1)

UAR:	123792711(CHEK1)

ELK:

111153780

LLV:

125110264

MPUF:

101685590(CHEK1)

MNP:	132026435(CHEK1)

MLK:	131838215(CHEK1)

NVS:	122912413(CHEK1)

ORO:	101362614(CHEK1)

EJU:	114226008(CHEK1)

ZCA:	113915303(CHEK1)

MLX:	118013370(CHEK1)

NSU:	110586234(CHEK1)

LWW:	102731543(CHEK1)

FCA:	101083365(CHEK1)

PYU:	121035597(CHEK1)

PCOO:

112865240(CHEK1)

PBG:	122483117(CHEK1)

PVIV:

125146989(CHEK1)

LRUF:

124505184

PTG:	102948766(CHEK1)

PPAD:

109257420(CHEK1)

PUC:

125939340

AJU:

106976641

HHV:	120243919(CHEK1)

BTA:	513678(CHEK1)

BOM:

102266500

BIU:	109554657(CHEK1)

BBUB:

102398478(CHEK1)

BBIS:

104980692(CHEK1)

CHX:	102184881(CHEK1)

OAS:	101111403(CHEK1)

BTAX:

128068939(CHEK1)

ODA:	120874428(CHEK1)

CCAD:

122430784(CHEK1)

MBEZ:

129548956(CHEK1)

SSC:	100511709(CHEK1)

CFR:	102505566(CHEK1)

CBAI:

105074175(CHEK1)

CDK:	105094454(CHEK1)

VPC:	102526561(CHEK1)

BACU:

103015970(CHEK1)

BMUS:

118900280(CHEK1)

LVE:	103073805(CHEK1)

OOR:	101270160(CHEK1)

DLE:	111167465(CHEK1)

PCAD:

102989266(CHEK1)

PSIU:

116757609(CHEK1)

NASI:

112396826(CHEK1)

ECB:	100064353(CHEK1)

EPZ:	103557005(CHEK1)

EAI:	106835962(CHEK1)

MYB:	102255905(CHEK1)

MYD:	102751668(CHEK1)

MMYO:

118678155(CHEK1)

MLF:	102437641(CHEK1)

MDT:	132221590(CHEK1)

PKL:	118725741(CHEK1)

EFUS:

103286938(CHEK1)

MNA:	107530590(CHEK1)

DRO:	112301845(CHEK1)

SHON:

118981405(CHEK1)

AJM:	119041045(CHEK1)

PDIC:

114509510(CHEK1)

PHAS:

123832554(CHEK1)

MMF:	118639911(CHEK1)

PPAM:

129086390(CHEK1)

HAI:	109391372(CHEK1)

RFQ:	117017223(CHEK1)

PALE:

102882405(CHEK1)

PGIG:

120610459(CHEK1)

PVP:	105296813(CHEK1)

RAY:	107498938(CHEK1)

MJV:	108401047(CHEK1)

TOD:	119240818(CHEK1)

SARA:

101540894(CHEK1) 105943527

SETR:

126016046(CHEK1)

LAV:	100658513(CHEK1)

TMU:

101345463

ETF:	101640005(CHEK1)

DNM:	101441252(CHEK1)

MDO:	100016170(CHEK1)

GAS:	123238925(CHEK1)

SHR:	100933648(CHEK1)

AFZ:

127554847

PCW:	110218134(CHEK1)

TVP:	118838477(CHEK1)

OAA:	100090345(CHEK1)

GGA:	374260(CHEK1)

PCOC:

116233040(CHEK1)

MGP:	100547861(CHEK1)

CJO:	107324224(CHEK1)

TPAI:

128087515(CHEK1)

LMUT:

125703744(CHEK1)

NMEL:

110387692(CHEK1)

APLA:

101790669(CHEK1)

ACYG:

106040556(CHEK1)

CATA:

118252468(CHEK1)

AFUL:

116497895(CHEK1)

TGU:	100219597(CHEK1)

LSR:	110468180(CHEK1)

SCAN:

103822842(CHEK1)

PMOA:

120508383(CHEK1)

OTC:	121340821(CHEK1)

PRUF:

121360614(CHEK1)

GFR:	102039036(CHEK1)

FAB:	101815748(CHEK1)

OMA:	130262435(CHEK1)

PHI:	102103508(CHEK1)

PMAJ:

107214301(CHEK1)

CCAE:

111939252(CHEK1)

CCW:	104692217(CHEK1)

CBRC:

103618545(CHEK1)

ETL:	114064599(CHEK1)

ZAB:	102064035(CHEK1)

ZLE:	135457438(CHEK1)

ACHL:

103807438(CHEK1)

SVG:	106860748(CHEK1)

MMEA:

130583027(CHEK1)

HRT:	120762582(CHEK1)

SATI:

136370965(CHEK1)

FPG:	101911598(CHEK1)

FCH:	102048652(CHEK1)

NNT:	104400295(CHEK1)

SHAB:

115616326(CHEK1)

ACUN:

113488427(CHEK1)

TALA:

116961442(CHEK1)

ACHC:

115344766(CHEK1)

HLE:	104840506(CHEK1)

AGEN:

126038521

GCL:

127025784

DPUB:

104308049(CHEK1)

EGZ:	104129228(CHEK1)

NNI:	104016679(CHEK1)

CLV:	102094428(CHEK1)

MUI:

104539884

PGUU:

104464013(CHEK1)

CUCA:

104066084(CHEK1)

CPEA:

104398046(CHEK1)

RTD:

128918724

AROW:

112968927(CHEK1)

ASN:	102385348(CHEK1)

AMJ:	102574519(CHEK1)

CPOO:

109317977(CHEK1)

GGN:	109291782(CHEK1)

PSS:	102451245(CHEK1)

CMY:	102945662(CHEK1)

CCAY:

125625503(CHEK1)

DCC:	119846783(CHEK1)

CPIC:

101933610(CHEK1)

TST:	117868633(CHEK1)

CABI:

116818797(CHEK1)

MRV:	120375393(CHEK1)

ACS:	100564808(chek1)

ASAO:

132782654(CHEK1)

PVT:	110070287(CHEK1)

PBI:	103064116(CHEK1)

PMUR:

107296402 107296403

CTIG:

120313956(CHEK1)

TSR:	106545333(CHEK1)

PGUT:

117668192(CHEK1)

APRI:

131203972(CHEK1)

PTEX:

113451811(CHEK1)

NSS:	113427162(CHEK1)

VKO:	123027171(CHEK1) 123033920

PMUA:

114585208(CHEK1)

PRAF:

128402660(CHEK1)

ZVI:	118097373(CHEK1)

HCG:	128333804(CHEK1)

GJA:	107117803(CHEK1)

STOW:

125442177(CHEK1)

EMC:	129342148(CHEK1)

XLA:	108696394(chek1.L) 398191(chek1.S)

XTR:	100038224(chek1)

NPR:	108783681(CHEK1) 108792688

RTEM:

120915700(CHEK1)

BBUF:

121000276(CHEK1)

BGAR:

122926812(CHEK1)

MUO:	115474693(CHEK1)

GSH:	117361002(CHEK1)

DRE:	393162(chek1)

SRX:	107706535 107719013

SANH:

107681196 107703487

SGH:	107548125 107551636

CCAR:

109069289 109099921(chek1)

CAUA:

113038615 113064276

CGIB:

127941762 127985384

PTET:

122326226(chek1)

LROH:

127152033(chek1)

OMC:	131529448(chek1)

PPRM:

120494746(chek1)

RKG:	130096492(chek1)

MAMB:

125253492(chek1)

CIDE:

127504163

CERY:

137012864(chek1)

MASI:

127429224

TROS:

130570377(chek1)

TDW:	130408027(chek1)

MANU:

129423375(chek1)

IPU:

108278491

IFU:	128622434(chek1)

PHYP:

113541633(chek1)

SMEO:

124398465(chek1)

TFD:	113634915(chek1)

TVC:	132859790(chek1)

TRN:	134330383(chek1)

AMEX:

103021956(chek1)

CMAO:

118820153(chek1)

EEE:	113573544(chek1)

CHAR:

105895358(chek1)

TRU:	101069769(chek1)

TFS:	130537480(chek1)

TNG:	GSTEN00018969G001

LCO:	104929933(chek1)

NCC:	104964655(chek1)

TBEN:

117490151(chek1)

CGOB:

115018952(chek1)

PGEO:

117458706(chek1)

GACU:

117535558(chek1)

EMAC:

134872535(chek1)

ELY:	117262759(chek1)

EFO:	125898268(chek1)

PLEP:

121952155(chek1)

SLUC:

116064872(chek1)

ECRA:

117955169(chek1)

ESP:	116700025(chek1)

PFLV:

114566919(chek1)

GAT:	120822688(chek1)

PPUG:

119215834(chek1)

AFB:	129113508(chek1)

CLUM:

117743221(chek1)

PSWI:

130189448(chek1)

MSAM:

119895100(chek1)

SCHU:

122888650(chek1)

CUD:	121518410(chek1)

ALAT:

119031422(chek1)

MZE:	101487018(chek1)

ONL:	100707719(chek1)

OAU:	116313090(chek1)

OLA:	101170780(chek1)

OML:	112140828(chek1)

CSAI:

133460279(chek1)

XMA:	102238315(chek1)

XCO:	114152470(chek1)

XHE:	116729004(chek1)

PRET:

103475471(chek1)

PFOR:

103142157(chek1)

PLAI:

106956156(chek1)

PMEI:

106921319(chek1)

GAF:	122844415(chek1)

PPRL:

129368826(chek1)

CVG:	107098496(chek1)

CTUL:

119775819(chek1)

GMU:	124875974(chek1) 124876660

NFU:	107386371(chek1)

KMR:	108236904(chek1)

ALIM:

106514075(chek1)

NWH:	119420041(chek1)

AOCE:

111580652(chek1)

MCEP:

125021744(chek1)

CSEM:

103395155(chek1)

POV:	109628292(chek1)

SSEN:

122779755(chek1)

HHIP:

117774183(chek1)

HSP:	118122685(chek1)

PPLT:

128456608(chek1)

SMAU:

118301186(chek1)

LCF:

108893136

SDU:	111234478(chek1)

SLAL:

111666155(chek1)

XGL:	120802605(chek1)

HCQ:	109517900(chek1)

SSCV:

125982679

SBIA:

133491952(chek1)

PEE:	133415819(chek1)

PTAO:

133467490(chek1)

BPEC:

110158508(chek1)

MALB:

109959175(chek1)

BSPL:

114869608(chek1)

SJO:	128371820(chek1)

SASA:

106563964(chek1)

STRU:

115204711(chek1)

OTW:	112236999(chek1)

OMY:	110510298(chek1)

OGO:	124007528(chek1)

ONE:	115123283(chek1)

OKI:	109881514(chek1)

OKE:	118371844(chek1)

SALP:

112078987(chek1)

SNH:	120041456(chek1)

CCLU:

121557942 123484461

ELS:	105009476(chek1)

SFM:	108924764(chek1)

PKI:	111837953(chek1)

AANG:

118235259(chek1)

LOC:	102696807(chek1)

PSPA:

121309546

ARUT:

117397432 117966660

LCM:	102357495(CHEK1)

CMK:	103180289(chek1)

RTP:	109921452(chek1)

CPLA:

122540735(chek1)

HOC:	132829610(chek1)

LERI:

129712431(chek1)

PMRN:

116948227(CHEK1)

LRJ:	133342135 133342142

BFO:

BBEL:

CIN:

SCLV:

SPU:	115921093 592974(Chk1)

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG17161(grp)

DER:

6547505

DSE:

6614402

DSI:	Dsimw501_GD24070(Dsim_GD24070)

DYA:	Dyak_GE12755

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17268

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108367897 108374399

AOQ:

129249321

TDA:

119688010

MDE:	101887980 101891848

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ005290

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105679793(grp)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209439

MJU:

VCD:

PMAC:

PXU:

PRAP:

ZCE:	119834269 119834698

LSIN:

AAGE:

HZE:

TNL:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

113375207 113375955 113375956

CCRN:

123291117

API:	100167829 100168998

DNX:	107161441 107166946

AGS:	114132433 114132783

RMD:	113552906 113556596

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106678732(grp)

NLU:

111063362

HVI:

124356593

MQU:	128985485 128986913

PHU:	Phum_PHUM346290

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_43327

DMK:

116930871

DPZ:

124348976

PVM:	113828085 113828090

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

ESN:

MNZ:

HAZT:

EAF:	111697548 111714424

LSM:

121114857

TCF:

131884332

PPOI:

119094268

DSV:	119456143 119456145

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:	124489978 124493819

CSCU:

111620828

CVS:	136975935(grp)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_Y39H10A.7(chk-1)

CBR:	CBG_06670(Cbr-chk-1) CBG_10664 CBG_10679 CBG_15809 CBG_16303

CRQ:	GCK72_007516 GCK72_007517 GCK72_019159

NAI:	NECAME_09582 NECAME_14937 NECAME_14939

LOA:	LOAG_12066

TSP:

Tsp_05158

HRO:	HELRODRAFT_189278

LGI:	LOTGIDRAFT_173967

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_077180

SHX:	MS3_00004470(CHEK1)

LLON:

135495982

NVE:	5501525 5502980

EPA:

110232258

ATEN:

116303765

ADF:	107336044 107355729

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_24287

AQU:

100640078

SCE:	YBR274W(CHK1)

SEUB:

DI49_1298

SPAO:

SPAR_B03700

AGO:	AGOS_AEL185C

ERC:

Ecym_6307

KLA:	KLLA0_F01276g

KMX:	KLMA_50053(CHK1)

LTH:	KLTH0H10318g

VPO:	Kpol_1035p17

ZRO:	ZYRO0B09196g

CGR:	2888933(GVI51_I09361)

NCS:	NCAS_0B07380(NCAS0B07380)

NDI:	NDAI_0B04700(NDAI0B04700)

TPF:	TPHA_0O01400(TPHA0O01400)

TGB:	HG536_0F02180

TDL:	TDEL_0D02040(TDEL0D02040)

KAF:	KAFR_0C04280(KAFR0C04280)

KNG:	KNAG_0C01820(KNAG0C01820)

ZMK:	HG535_0C04790

SLUD:

SCDLUD_003576

DHA:	DEHA2C08272g

PIC:	PICST_33177(CHK1)

PPA:	PAS_chr4_0585

PKZ:	C5L36_0B06200

BNN:	FOA43_003336

BBRX:

BRETT_004182

OPA:	HPODL_02468

SLB:	AWJ20_2911(CHK1)

NCR:	NCU08346(un-1)

NTE:	NEUTE1DRAFT114358(NEUTE1DRAFT_114358)

SMP:	10810403(SMAC4_01615)

PAN:	PODANSg09646

PBEL:

QC761_103950(chk1)

PPSD:

QC762_103950(chk1)

PPSP:

QC763_103950(chk1)

PPSA:

QC764_103950(chk1)

TTT:	THITE_2121159

MTM:	MYCTH_2294445

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_3639

SSCK:

SPSK_04135

FGR:	FGSG_01506

FPU:	FPSE_05009

FPOA:

FPOAC1_001616

FVN:	FVRRES_01825

FVR:	FVEG_09569

FOX:	FOXG_11222

NHE:	NECHADRAFT_29794

FFC:	NCS54_00034600

FKR:	NCS57_00032700

FMU:	J7337_000394

TRE:	TRIREDRAFT_78309

TRR:	M419DRAFT_94781

TATV:

25786232(TrAtP1_006010)

TASP:

36617061(TrAFT101_005314)

MAW:	19251924(chk1)

MAJ:

MAA_00521

MBRN:

26242721(chk1)

PCHM:

VFPPC_01168

CMT:

CCM_05529

AMUS:

LMH87_005970

PLJ:	28891115(PLICBS_004573)

PTKZ:

JDV02_009433(chk1)

VAL:	VDBG_03742

VDA:	VDAG_00976

CFJ:	CFIO01_11006

CLUP:

CLUP02_13958

CHIG:

CH63R_05995

ELA:	UCREL1_9719

PFY:	PFICI_13672

SSL:	SS1G_12179

BFU:	BCIN_05g06110(Bcchk1)

MBE:

MBM_03411

PSCO:

LY89DRAFT_703354

GLZ:	GLAREA_08424

ANI:	ANIA_05494

AFM:	AFUA_6G13160

ACT:	ACLA_086410

NFI:	NFIA_059080

AOR:	AO090003000441

ANG:	An08g10320

AFV:	AFLA_001250

ALUC:

AKAW2_51828S(CHK1)

ACHE:

ACHE_10546A(CHK1)

APUU:

APUU_40831A(CHK1)

PCS:	N7525_005968

PDP:	PDIP_45050

POU:	POX_a01816

TMF:	EYB26_003859

TRG:	TRUGW13939_10504

CIM:	CIMG_01668

CPW:	CPC735_048120

URE:	UREG_05390

ABE:

ARB_07449

TVE:

TRV_03991

PBL:	PAAG_04978

PBN:	PADG_04831

BGH:	BDBG_03611

PNO:	SNOG_05179

PTE:

PTT_09831

PTRR:

6342420(PtrM4_090710)

BZE:	COCCADRAFT_4193

BSC:	COCSADRAFT_126193

BOR:	COCMIDRAFT_27857

AALT:

CC77DRAFT_993861

ARAB:

EKO05_0007208

ZTR:	MYCGRDRAFT_64195

PFJ:	MYCFIDRAFT_202945

FFU:	CLAFUR5_13969

CBET:

CB0940_04954

BCOM:

BAUCODRAFT_436646

NPA:	UCRNP2_9008

TML:	GSTUM_00001636001

SPO:	2539087(chk1)

SOM:	SOMG_03044(chk1)

CNE:

CNG04000

CNB:

CNBG0730

CNG:	CNAG_03167

CGI:	CGB_G1060W

CDEU:

CNBG_2417

CDEP:

91089408(L203_105199)

KMG:	30163672(I203_102885)

KNE:	92182323(IAR55_005065)

TMS:	TREMEDRAFT_27276

TASA:

A1Q1_03668

CCAC:

CcaHIS019_0404340(chk1)

TVS:	TRAVEDRAFT_66216

DSQ:	DICSQDRAFT_86244

PCO:	PHACADRAFT_175408

SHS:	STEHIDRAFT_82972

HIR:	HETIRDRAFT_331300

PSQ:	PUNSTDRAFT_107114

ADL:	AURDEDRAFT_79137

FME:	FOMMEDRAFT_16344

GTR:	GLOTRDRAFT_48573

RSX:	RhiXN_00514

LBC:	LACBIDRAFT_304059

CCI:	CC1G_02812

ABP:	AGABI1DRAFT122426(AGABI1DRAFT_122426) AGABI1DRAFT132921(AGABI1DRAFT_132921)

ABV:	AGABI2DRAFT120023(AGABI2DRAFT_120023) AGABI2DRAFT122240(AGABI2DRAFT_122240)

PCUB:

JR316_0001487

MRR:	Moror_10767

E1B28_002201 E1B28_005677

CPUT:

CONPUDRAFT_113983

SLA:	SERLADRAFT_453634

UMA:	UMAG_11087

PFP:	PFL1_02244

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_00714

PTRC:

PtA15_1A599

PSTR:

Pst134EA_000319

MLR:	MELLADRAFT_102390

ECU:	ECU03_0620

EHE:	EHEL_030530

NCE:	NCER_101336

VNX:	VNE69_10075

MBR:	MONBRDRAFT_25225

SRE:	PTSG_00462

PTM:	GSPATT00018223001

» show all

Reference

PMID:18451105

Authors

Yang XH, Shiotani B, Classon M, Zou L

Title

Chk1 and Claspin potentiate PCNA ubiquitination.

Journal

Genes Dev 22:1147-52 (2008)
DOI:10.1101/gad.1632808

Sequence

[hsa:1111]

Reference

PMID:18566216

Authors

Huang M, Miao ZH, Zhu H, Cai YJ, Lu W, Ding J

Title

Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins.

Journal

Mol Cancer Ther 7:1440-9 (2008)
DOI:10.1158/1535-7163.MCT-07-2116

Sequence

[hsa:1111]

Reference

PMID:9278511

Authors

Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ

Title

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.

Journal

Science 277:1497-501 (1997)
DOI:10.1126/science.277.5331.1497

Sequence

[hsa:1111]

DBGET integrated database retrieval system