KEGG ORTHOLOGY: K02223

ORTHOLOGY: K02223

Entry

K02223                      KO

Symbol

CLOCK, KAT13D

Name

circadian locomoter output cycles kaput protein [EC:2.3.1.48]

Pathway

map04710

Circadian rhythm

map04711

Circadian rhythm - fly

map04728

Dopaminergic synapse

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
  09159 Environmental adaptation
   04710 Circadian rhythm
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
   04711 Circadian rhythm - fly
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
   03036 Chromosome and associated proteins
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
Transcription factors [BR:ko03000]
Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein

Other DBs

GO:

0004402

Genes

HSA:	9575(CLOCK)

PTR:	461312(CLOCK)

PPS:	100986920(CLOCK)

GGO:	101140472(CLOCK)

PON:	100172630(CLOCK)

PPYG:

129034790(CLOCK)

NLE:	100606130(CLOCK)

HMH:	116467567(CLOCK)

SSYN:

129491009(CLOCK)

MCC:	697532(CLOCK)

MCF:	102131896(CLOCK)

MTHB:

126954737

MNI:	105463534(CLOCK)

CSAB:

103235664(CLOCK)

CATY:

105592012(CLOCK)

PANU:

101017477(CLOCK)

TGE:	112624744(CLOCK)

MLEU:

105548474(CLOCK)

RRO:	104662031(CLOCK)

RBB:	108531597(CLOCK)

TFN:	117085596(CLOCK)

PTEH:

111526472(CLOCK)

CANG:

105525912(CLOCK)

CJC:	100407407(CLOCK)

SBQ:	101035173(CLOCK)

CIMI:

108312351(CLOCK)

ANAN:

105709199(CLOCK)

CSYR:

103249187(CLOCK)

MMUR:

105867862(CLOCK)

LCAT:

123624845(CLOCK)

PCOQ:

105807668(CLOCK)

OGA:	100962800(CLOCK)

MMU:	12753(Clock)

MCAL:

110294104(Clock)

MPAH:

110330520(Clock)

RNO:	60447(Clock)

MCOC:

116071288(Clock)

ANU:	117712510(Clock)

MUN:	110556888(Clock)

CGE:	100770092(Clock)

MAUA:

101830807(Clock)

PROB:

127232282(Clock)

PLEU:

114682808(Clock)

MORG:

121460743(Clock)

MFOT:

126506597

AAMP:

119827642(Clock)

NGI:	103734387(Clock)

HGL:	101725536(Clock)

CPOC:

100728432(Clock)

CCAN:

109702259(Clock)

DORD:

105980293(Clock)

DSP:	122106772(Clock)

PLOP:

125364943(Clock)

NCAR:

124994065

MMMA:

107139243(Clock)

OCU:

100349684

OPI:	101536193(CLOCK)

TUP:	102478751(CLOCK)

GVR:	103597796(CLOCK)

CFA:	475145(CLOCK)

CLUD:

112652336(CLOCK)

VVP:	112923720(CLOCK)

VLG:	121472850(CLOCK)

NPO:	129519977(CLOCK)

AML:	100463987(CLOCK)

UMR:	103672743(CLOCK)

UAH:	113262508(CLOCK)

UAR:	123804050(CLOCK)

ELK:

111149069

LLV:

125093736

MPUF:

101674500(CLOCK)

MNP:	132006408(CLOCK)

MLK:	131823976(CLOCK)

NVS:	122890472(CLOCK)

ORO:	101369995(CLOCK)

EJU:	114206655(CLOCK)

ZCA:	113925712(CLOCK)

MLX:	118010514(CLOCK)

NSU:	110590743(CLOCK)

LWW:	102748823(CLOCK)

FCA:	101088483(CLOCK)

PYU:	121035444(CLOCK)

PCOO:

112858052(CLOCK)

PBG:	122478860(CLOCK)

PVIV:

125163356(CLOCK)

LRUF:

124520471

PTG:	102954901(CLOCK)

PPAD:

109278868(CLOCK)

PUC:

125922736

AJU:

106971676

HHV:	120243027(CLOCK)

BTA:	100300400(CLOCK)

BOM:	102284331(CLOCK)

BIU:	109560481(CLOCK)

BBUB:

102414002(CLOCK)

BBIS:

105002842(CLOCK)

CHX:	102175105(CLOCK)

OAS:	100171391(CLOCK)

BTAX:

128049703(CLOCK)

ODA:	120862132(CLOCK)

CCAD:

122428408(CLOCK)

MBEZ:

129561775(CLOCK)

SSC:	100628097(CLOCK)

CFR:	102520407(CLOCK)

CBAI:

105077732(CLOCK)

CDK:	105091544(CLOCK)

VPC:	102529531(CLOCK)

BACU:

103000125(CLOCK)

BMUS:

118895977(CLOCK)

LVE:	103086785(CLOCK)

OOR:	101289553(CLOCK)

DLE:	111169624(CLOCK)

PCAD:

102987634(CLOCK)

PSIU:

116754341(CLOCK)

NASI:

112400752(CLOCK)

ECB:	100034166(CLOCK)

EPZ:	103561742(CLOCK)

EAI:	106836920(CLOCK)

MYB:	102257849(CLOCK)

MYD:	102759548(CLOCK)

MMYO:

118668934(CLOCK)

MLF:	102440615(CLOCK)

MDT:	132218918(CLOCK)

PKL:	118706530(CLOCK)

EFUS:

103285047(CLOCK)

MNA:	107532833(CLOCK)

DRO:	112322438(CLOCK)

SHON:

118978606(CLOCK)

AJM:	119061663(CLOCK)

PDIC:

114493338(CLOCK)

PHAS:

123815714(CLOCK)

MMF:	118638437(CLOCK)

PPAM:

129065520(CLOCK)

HAI:	109381806(CLOCK)

RFQ:	117022236(CLOCK)

PALE:

102897617(CLOCK)

PGIG:

120588086(CLOCK)

PVP:	105293806(CLOCK)

RAY:	107520892(CLOCK)

MJV:	108398515(CLOCK)

TOD:	119261361(CLOCK)

SARA:

101546890(CLOCK)

SETR:

126032278(CLOCK)

LAV:	100656519(CLOCK)

TMU:

101347694

ETF:	101643504(CLOCK)

DNM:	101423732(CLOCK)

MDO:	100017022(CLOCK)

GAS:	123252396(CLOCK)

SHR:	100928316(CLOCK)

AFZ:

127540961

PCW:	110200139(CLOCK)

TVP:	118853262(CLOCK)

OAA:	100075694(CLOCK)

GGA:	373991(CLOCK)

PCOC:

116225920(CLOCK)

MGP:	100008576(CLOCK)

CJO:	107313727(CLOCK)

TPAI:

128079867(CLOCK)

LMUT:

125691570(CLOCK)

NMEL:

110397441(CLOCK)

APLA:

101797949(CLOCK)

ACYG:

106030790(CLOCK)

CATA:

118250878(CLOCK)

AFUL:

116488426(CLOCK)

TGU:	100219382(CLOCK)

LSR:	110470537(CLOCK)

SCAN:

103825235(CLOCK)

PMOA:

120497365(CLOCK)

OTC:	121334927(CLOCK)

PRUF:

121350921(CLOCK)

GFR:	102044439(CLOCK)

FAB:	101821455(CLOCK)

OMA:	130252534(CLOCK)

PHI:	102112793(CLOCK)

PMAJ:

107202959(CLOCK)

CCAE:

111928016(CLOCK)

CCW:	104690627(CLOCK)

CBRC:

103622464(CLOCK)

ETL:	114058328(CLOCK)

ZAB:	102066123(CPEB2) 102071580(CLOCK)

ZLE:	135446535(CLOCK)

ACHL:

103803546(CLOCK)

SVG:	106851469(CLOCK)

MMEA:

130573951(CLOCK)

HRT:	120752627(CLOCK)

SATI:

136360056(CLOCK)

FPG:	101913246(CLOCK)

FCH:	102054484(CLOCK)

CCRI:

104158991(CLOCK)

NNT:

104409500

SHAB:

115610951(CLOCK)

ACUN:

113479085(CLOCK)

TALA:

104358378(CLOCK)

ACHC:

115340608(CLOCK)

HALD:

104322714(CLOCK)

HLE:	104836129(CLOCK)

AGEN:

126051789

GCL:

127015682

LDI:	104345175(CLOCK)

MNB:

103778008

DPUB:

104299133(CLOCK)

AVIT:

104274434(CLOCK)

BRHI:

104496995(CLOCK)

EGZ:	104129500(CLOCK)

NNI:	104020777(CLOCK)

PCRI:

104031820

PCAO:

104044514(CLOCK)

PADL:

103926286(CLOCK)

AFOR:

103897400(CLOCK)

FGA:

104070553

GSTE:

104252543(CLOCK)

CLV:	102087081(CLOCK)

MUI:	104536434(CLOCK)

PGUU:

104461901(CLOCK)

PLET:

104628520(CLOCK)

EHS:	104508981(CLOCK)

CMAC:

104482777(CLOCK)

CUCA:

104067137(CLOCK)

TEO:	104375180(CLOCK)

BREG:

104631100(CLOCK)

OHA:	104334895(CLOCK)

ACAR:

104523448(CLOCK)

CPEA:

104393036(CLOCK)

CVF:	104286394(CLOCK)

RTD:	128909793(CLOCK)

AAM:	106490149(CLOCK)

AROW:

112975831(CLOCK)

NPD:	112942560(CLOCK)

TGT:	104565612(CLOCK)

DNE:	112979428(CLOCK)

SCAM:

104138540(CLOCK)

ASN:	102379511(CLOCK)

AMJ:	102567584(CLOCK)

CPOO:

109322228(CLOCK)

GGN:	109304031(CLOCK)

PSS:	102444504(CLOCK)

CMY:	102941363(CLOCK)

CCAY:

125635905(CLOCK)

DCC:	119854340(CLOCK)

CPIC:

101937929(CLOCK)

TST:	117878593(CLOCK)

CABI:

116826033(CLOCK)

MRV:	120406110(CLOCK)

ACS:	100552330(clock)

ASAO:

132776656(CLOCK)

PVT:	110078394(CLOCK)

SUND:

121931061(CLOCK)

PBI:	103063171(CLOCK)

PMUR:

107292122(CLOCK) 107300605

CTIG:

120316817(CLOCK)

TSR:	106548317(CLOCK)

PGUT:

117662095(CLOCK)

APRI:

131202886(CLOCK)

PTEX:

113435830(CLOCK)

NSS:	113417942(CLOCK)

VKO:	123016932(CLOCK)

PMUA:

114604715(CLOCK)

PRAF:

128421431(CLOCK)

ZVI:	118083328(CLOCK)

HCG:	128326641(CLOCK)

GJA:	107106037(CLOCK)

STOW:

125440403(CLOCK)

EMC:	129337097(CLOCK)

XLA:	108706595(clock.S) 399157(clock.L)

XTR:	100038163(clock)

NPR:	108803914(CLOCK)

RTEM:

120922786(CLOCK)

BBUF:

120990203(CLOCK)

BGAR:

122941807(CLOCK)

MUO:	115462190(CLOCK)

GSH:	117360772(CLOCK)

DRE:	30140(clocka) 352927(clockb)

SRX:	107718423 107746006 107754154 107755212

SANH:

107656111 107683961 107701480 107702364

SGH:	107551585 107568120 107573987 107591535 107601911(clock)

CCAR:

109044823(clock) 109066967

CAUA:

113044203 113063324 113106618 113106984 113120992

CGIB:

127938573 127963180 127983949 127987525

PTET:

122341736(clockb) 122342750(clocka)

LROH:

127166259(clockb) 127183139(clocka)

OMC:	131526823(clocka) 131532529(clockb)

PPRM:

120493483(clocka) 120493503(clockb)

RKG:	130089510(clockb) 130097538(clocka)

MAMB:

125272587(clockb) 125277991(clocka)

CIDE:

127501867 127510739

CERY:

137018879(clocka) 137031955(clockb)

MASI:

127409862 127415739 127443356 127444702

TROS:

130552695(clockb) 130565648(clocka)

TDW:	130434071(clocka) 130440088(clockb)

MANU:

129429221(clocka) 129444734(clockb)

IPU:	108257920(clocka) 108260793(clockb)

IFU:	128600860(clocka) 128604214(clockb)

PHYP:

113544362 113545188(clock)

SMEO:

124377028(clocka) 124381437(clockb)

TFD:	113642579(clocka) 113660732(clockb)

TVC:	132841886(clockb) 132843452(clocka)

TRN:	134319988(clocka) 134326341(clockb)

AMEX:

103025395(clockb) 103040704(clocka)

CMAO:

118815394(clocka) 118816584(clockb)

EEE:	113567705 113586381(clock) 113591593

CHAR:

105895219(clocka) 105908495(clockb)

TRU:	101072867 101078879

TFS:	130527084(clockb) 130528420(clocka)

TNG:	GSTEN00006765G001 GSTEN00032758G001

LCO:	104919094(clock) 104939547

NCC:	104947079(clock) 104968026

TBEN:

117481678 117496173(clocka)

CGOB:

115006717(clock) 115009851

PGEO:

117445733(clockb) 117445826(clocka)

GACU:

117537954(clockb) 117555237(clocka)

EMAC:

134864825 134869282(clocka)

ELY:	117253325(clocka) 117255396(clockb)

EFO:	125886623 125895638(clocka)

PLEP:

121940342(clocka) 121941889

SLUC:

116040458(clockb) 116058742(clocka)

ECRA:

117936516(clockb) 117950152(clocka)

ESP:	116695599 116706880

PFLV:

114561591(clock) 114572646

GAT:	120824892(clockb)

PPUG:

119217783(clockb)

AFB:	129094564(clocka) 129095343(clockb)

CLUM:

117729242(clocka) 117730508(clockb)

PSWI:

130190007(clockb)

MSAM:

119894693(clocka) 119899138

SCHU:

122873230(clockb) 122877333(clocka)

CUD:	121508281 121512592(clocka)

ALAT:

119020669(clockb) 119028119(clocka)

MZE:	101473932 101478070

ONL:	100690629 100703460

OAU:	116325997(clockb) 116331167(clocka)

OLA:	101163159(clock) 101165450

OML:	112136976 112157001(clockb)

CSAI:

133456933(clockb) 133458272(clocka)

XMA:	102219340 102234992(clock)

XCO:	114144178 114150659(clock)

XHE:	116719796 116726021(clock)

PRET:

103463833(clock) 103468951

PFOR:

103137111(clock) 103137774

PLAI:

106954374 106963416(clock)

PMEI:

106918699 106924117

GAF:	122829536(clockb) 122838025(clocka)

PPRL:

129376630(clocka)

CVG:	107091551(clock) 107093492

CTUL:

119780636(clocka) 119788452(clockb)

GMU:	124868635(clockb) 124874039(clocka)

NFU:	107382188 107393399(clock)

KMR:	108241552(clockb) 108243364(clocka)

ALIM:

106515206(clock)

NWH:

119430791

AOCE:

111569579(clock) 111569807

MCEP:

125003667(clockb) 125009080(clocka)

CSEM:

103376701(clock) 103383760

POV:	109625881(clock) 109637843

SSEN:

122760329(clockb) 122769730(clocka)

HHIP:

117759683(clocka) 117760301(clockb)

HSP:	118120305 118121615(clocka)

PPLT:

128433966(clockb) 128447698(clocka)

SMAU:

118312519(clockb) 118318589(clocka)

LCF:	108879109(clocka) 108896436

SDU:	111226339(clock) 111231527

SLAL:

111644362(clock) 111664538

XGL:	120790866(clocka) 120800034(clockb)

HCQ:	109511238 109532108

SSCV:

125967141 125968581

SBIA:

133503369(clocka) 133505792

PEE:	133403773 133406054(clocka)

PTAO:

133477075(clockb) 133481405(clocka)

BPEC:

110154690(clock) 110172558

MALB:

109958403 109961996

BSPL:

114852972(clockb) 114853927(clocka)

SJO:	128362113(clocka) 128368896(clockb)

SASA:

106560272 106584123(clock) 106594386

STRU:

115158534 115190785 115190786 115192380(clock)

OTW:	112249169(clocka) 112251141

OMY:	100135915 110513597 110521676(clocka) 118936633

OGO:	123996813 124018469 124037863(clocka)

ONE:	115108538 115145135(clock)

OKI:	109887115 109898030(clock) 109902721

OKE:	118359030(clocka) 118383006 118392568

SALP:

111972321(clock) 111975703

SNH:	120036034(clockb) 120051867 120054929

CCLU:

121533952 121540149(clocka) 121551709

ELS:	105011842(clock) 105020861

SFM:	108922741(clock)

PKI:	111850120(clock)

AANG:

118225583(clocka)

LOC:

102696965

PSPA:

121298178 121320081(clocka)

ARUT:

117409483 117421158

PSEX:

120528719(clocka)

LCM:	102363676(CLOCK)

CMK:	103178171(clocka)

RTP:	109934781(clocka)

CPLA:

122550104(clocka)

HOC:	132819300(clocka)

PMRN:

116942863

LRJ:

133342891

BFO:

118418936

SPU:	100889647 576191

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG7391(Clk)

DER:

6543946

DSE:

6604777

DSI:	Dsimw501_GD13034(Dsim_GD13034)

DYA:	Dyak_GE20389

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI12195

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101889860 131805379

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ002146 CpipJ_CPIJ002147

CPII:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:	105182101 105190712

DQU:

106742585

CFO:	105251019 105257275

FEX:

115237720

LHU:	105676055(Clk) 105678065

PGC:	109852004 109861318

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100114103 100123168

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	655469(Clk)

DPA:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_206046

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PGW:

LGLY:

CCRN:

API:	100163752(clk)

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM426300

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_346996(CLOCK)

DMK:

DPZ:

PVM:

PJA:

PCHN:

PTRU:

EAF:

LSM:

VJA:

TUT:

CVS:	136974085(Clk)

PTEP:

ABRU:

UDV:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

NVE:	5506840 5519866

EPA:	110232062 110251036 110252532

ATEN:

116307440

ADF:	107345125 107348463 107349953

AMIL:

114964640 114969846

PDAM:

113667617 113681287

SPIS:

111321901 111322834 111326918

» show all

Reference

PMID:9630223

Authors

Allada R, White NE, So WV, Hall JC, Rosbash M

Title

A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless.

Journal

Cell 93:791-804 (1998)
DOI:10.1016/s0092-8674(00)81440-3

Sequence

[dme:Dmel_CG7391]

Reference

PMID:16448219

Authors

Kaeffer B, Pardini L

Title

Clock genes of Mammalian cells: practical implications in tissue culture.

Journal

In Vitro Cell Dev Biol Anim 41:311-20 (2005)
DOI:10.1007/s11626-005-0001-7

Reference

PMID:14769864

Authors

Isojima Y, Okumura N, Nagai K

Title

Molecular mechanism of mammalian circadian clock.

Journal

J Biochem 134:777-84 (2003)
DOI:10.1093/jb/mvg219

All links

Ontology (5)   
   KEGG BRITE (4)   
   GO (1)   
Pathway (6)   
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Chemical reaction (1)   
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Gene (1437)   
   KEGG GENES (763)   
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Literature (3)   
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All databases (1452)   

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